Clinical trials: Vitamin B 12 Deficiency
Deficiency, Vitamin, Vegan's Anemia (Vitamin B12 Deficiency)
Supplementation of Critical Nutrients in a Plant-based Diet
500 participants of the vegan/vegetarian congress VegMed are to be included, which should answer once (cross-sectional study) a medicine socio-behaviorist questionnaire on the topic "supplementation of critical nutrients in a…
- Conditions
- Deficiency, Vitamin, Vegan's Anemia (Vitamin B12 Deficiency), Deficiencies Micronutrient
- Trial name
- NCT03542591
- Testing
- Questionnaire on the topic "Supplementation of critical nutrients in a plant-based diet"
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Charite University, Berlin, Germany
Anemia, Iron-deficiency
Preoperative Anaemia prevaLence In surgiCal patiEnts
Preoperative anaemia is common in surgery, with a prevalence between 10 and 50 %, and is an independent risk factor for morbidity and mortality.
- Conditions
- Anemia, Iron-deficiency, Folic Acid Deficiency, Vitamin B 12 Deficiency
- Trial name
- ALICE (NCT03978260)
- Where
- Germany
- Volunteers
- 2,500 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Vitamin B 12 Deficiency
Cobalamin Deficiency - Diagnosis and Therapy
In a retrospective study with existing values of vitamin B12 and holotranscobalamin 4 strategies are simulated and the results and costs are compared. Generally, cobalamin ist substituted by intramuscular administration.
- Trial name
- NCT04243707
- Where
- Switzerland
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Vitamin B12 Nutritional Deficiency
Effect of Methylcobalamin and Cyanocobalamin Consumption on Vitamin B12 Nutritional Status
Vitamin B12 (B12, Cobalamin) is an essential micronutrient that humans are not capable of synthesizing and therefore must be ingested through food. In nature, B12 is basically only present in foods of animal origin.
- Trial name
- NORMB12 (NCT05785585)
- Testing
- Methylcobalamin, Cyanocobalamin group, Control group
- Where
- 2 sites in Spain
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Vitamin A Deficiency, Iron-deficiency
Effect of Household Use of Multiple Micronutrient-fortified Bouillon on Micronutrient Status Among Women and Children in Two Districts in the Northern Region of Ghana
Background: Micronutrient (MN) deficiencies are severe and widespread in West Africa, particularly among young children and women of reproductive age.
- Conditions
- Vitamin A Deficiency, Iron-deficiency, Folate Deficiency, Vitamin B 12 Deficiency
- Trial name
- NCT05178407
- Testing
- Multiple micronutrient-fortified bouillon cube, Control bouillon cube (iodine-only)
- Where
- Ghana
- Volunteers
- 2,372 people
- Sponsor
- University of California, Davis
COVID, Zinc Deficiency
Evaluation of the Relationship Between Zinc Vitamin D and b12 Levels in the Covid-19 Positive Pregnant Women
Zinc d vitamin and b12 serum levels in covid-19 positive pregnants will be compared in terms of patients' responses to computed tomography and treatment.
- Conditions
- COVID, Zinc Deficiency, Vitamin D Deficiency
- Trial name
- NCT04407572
- Testing
- Serum zinc, vitamin d vitamin b12 levels .
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Anemia in Pregnancy, Pre-eclampsia
A Retrospective Analysis of Neevo® and NeevoDHA® Compared to a Standard Prenatal Vitamin in Anemia During Pregnancy
This study is a multi-site, retrospective chart review to determine the effect of Neevo® or NeevoDHA® (with higher folate and B12) versus standard prenatal vitamins on hemoglobin (Hgb) levels in pregnant women throughout the…
- Trial name
- NCT01193192
- Testing
- Neevo®, Prenatal vitamins
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pamlab, L.L.C.
Alopecia Areata, Alopecia Totalis
The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic
The study series consists of three studies with the aim to assess the incidence, prevalence, risk factors, comorbidities and management of patients with alopecia areata in Czech Republic based on the patients and registry of a…
- Conditions
- Alopecia Areata, Alopecia Totalis, Alopecia Universalis, Alopecia Areata (& Ophiasis)
- Trial name
- NCT05098600
- Testing
- Exposure of interest
- Where
- Czechia
- Volunteers
- 123 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Vitamin B12 Deficiency
How Many Patients Are in Need of Vitamin B12 Injections?
The clinical consequences of vitamin B12 deficiency include megaloblastic anemia and neurological disorders. Therefore, a proper and timely diagnosis and treatment is important.
- Trial name
- NCT00326833
- Testing
- vitamin B12
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Cobalamin Deficiency
Effect of Toothpaste Fortified With Cyanocobalamin on Vitamin B12 Status
A 3 months randomized, placebo-controlled study on the effect of toothpaste fortified with vitamin B12 on vitamin B12 status markers and related metabolic markers.
- Trial name
- NCT02679833
- Testing
- Cyanocobalamin
- Where
- 2 sites in Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universität des Saarlandes
Methylmalonic Acidemia (MMA)
A Study to Evaluate the Effects and Safety of Hydroxocobalamin in Participants With Combined Methylmalonic Academia (cblC Type)
This study is a Single-Center, Single-Arm, open-label, Phase III clinical study to evaluate the efficacy, safety characteristics of Hydroxocobalamin Chloride Injection (20 mg/mL) for Maintenance Therapy in participants with…
- Trial name
- NCT07163364
- Testing
- Hydroxocobalamin Chloride Injection
- Volunteers
- 20 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Organic Acidemia, Methylmalonic Acidemia
Clinical and Laboratory Study of Methylmalonic Acidemia
Methylmalonic acidemia (MMA), one of the most common inborn errors of organic acid metabolism, is heterogeneous in etiology and clinical manifestations.
- Conditions
- Organic Acidemia, Methylmalonic Acidemia, Inborn Errors of Metabolism
- Trial name
- NCT00078078
- Where
- 3 sites in United States
- Volunteers
- 2,275 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Vitamin B-12 Deficiency
THE B-BABIES STUDY: An Observational Study of Group B Vitamins in Preterm Infants
Infancy may be associated with a risk of micronutrient depletion due to the high demands of rapid growth. This is particularly true when preterm birth occurs, as the period before term exhibits the highest rate of bodily growth…
- Trial name
- B-BABIES (NCT07163962)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Nutritional Status, Nutrient Deficiency
Challenges in Achieving Adequate Dietary Status of Women
The aim of the study is to investigate the dietary habits of women of reproductive age (20-49 years). We aim to obtain epidemiological data on the intake and adequacy of key macronutrients and micronutrients, as well as to…
- Conditions
- Nutritional Status, Nutrient Deficiency, Micronutrient Deficiency, Vitamin D Deficiency
- Trial name
- NutriFem (NCT06745817)
- Testing
- Assessement of nutritional status, Dermis density and thickness, Skin elasticity
- Where
- 3 sites in Slovenia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Anemia, Folate Deficiency
Quadruple Fortified Salt Trial in India
Women of reproductive age are at an increased risk of anemia and micronutrient deficiencies. Evidence supports the role of periconceptional nutrition in the development of neural tube defects and other pregnancy complications.
- Conditions
- Anemia, Folate Deficiency, Vitamin B 12 Deficiency
- Trial name
- QFS (NCT03853304)
- Testing
- + Folic acid, + Vitamin B12, DFS
- Where
- India
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cornell University
Vitamin B 12 Deficiency
Cobalamin Status in Young Children With Developmental Delay
During fetal life and infancy, an adequate cobalamin status is important for normal growth and central nervous system development.
- Trial name
- NCT00710138
- Testing
- Hydroxycobalamin (Vitamin B12 Depot, Nycomed Pharma)
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Haukeland University Hospital
Diabetes Mellitus Type 2
Study to Identify Adequate Biomarker to Detect Vitamin B12 Deficiency in Type 2 Diabetic Patients Treated With Metformin
In this study we compare the vitamin B12 status by measuring serum vitamin B12 and holotranscobalamin in type 2 diabetic patients with and without metformin treatment.
- Trial name
- NCT02111967
- Testing
- Questionnaire administration, Laboratory biomarker analysis
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Basel, Switzerland
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
Vitamin B 12 Deficiency
Efficacy and Safety Study of Oral Eligen® B12 in Subjects With Low Serum Cobalamin
The purpose of this study is to compare the efficacy and safety profile of a new oral vitamin B12 formulation (Eligen® B12) with intramuscular B12 in restoring normal B12 (cobalamin) concentrations in subjects with low cobalamin…
- Trial name
- NCT01312831
- Testing
- Vitamin B12 (cyanocobalamin)
- Volunteers
- 49 people
- Sponsor
- Emisphere Technologies, Inc.
Iron Deficiency Anemia, B12 Deficiency Anemia
Do Iron And Vitamin B12 Injections Given Together, Improve Hemoglobin In Patients On Hemodialysis?
A parallel group, quadruple blind, placebo-controlled, randomized control trial with 2x2 factorial design to determine the effect of simultaneous IV ferric carboxymaltose and IM hydroxycobalamin supplementation in anemic Indian…
- Trial name
- ALOHA (NCT04627181)
- Testing
- Ferric carboxymaltose, Hydroxycobalamin
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Christian Medical College, Vellore, India