Clinical trials: Visual Impairments
Visual Impairment Due to Diabetic Macular Edema
24 Week Study to Compare Systemic VEGF-levels of Ranibizumab and Aflibercept in DME.
The purpose of the study is to compare the effect of intravitreal injections of ranibizumab and aflibercept on systemic VEGF levels in DME patients in a detailed time course.
- Trial name
- TIDE DME (NCT02878681)
- Testing
- Ranibizumab, Aflibercept
- Sponsor
- Novartis Pharmaceuticals
Concussion, Eye
The Effects of Concussion on Gait and Posture in Individuals With Peripheral Vision Loss
Changes in gait and balance often occur in individuals who have suffered a concussion. In addition, a subset of concussed individuals also experience peripheral vision loss.
- Trial name
- NCT05948501
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gaylord Hospital, Inc
Retinopathy of Prematurity (ROP), Prematurity Complications
Retinopathy of Prematurity - Visual Function and Retinal Structure
Children born prematurely may develop a characteristic retinal disease named retinopathy of prematurity (ROP). This disease could lead to retinal detachment and blindness.
- Conditions
- Retinopathy of Prematurity (ROP), Prematurity Complications, Cerebral Visual Impairment, Visual Field Defect
- Trial name
- NCT07427719
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Ocular Conditions Resulting in Visual Impairment
Low Vision Patients' Preference for Colored Filters and Illumination for Near Reading Determined by the LuxIQ/2
The effect of tinted filters and illumination on the visual performance of patients with low vision (i.e., individuals with reduced vision that is uncorrectable with glasses, surgery or treatments) has been a topic of research…
- Trial name
- NCT03192722
- Testing
- Colored near reading glasses, Lighting as determined by LuxIQ/2 or OttLite Cobra
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Nova Southeastern University
Hearing Loss, Hearing Loss, Age-Related
Sight and Hearing Investigation Into Effects on Delirium
The goal of this observational study is to learn about sensory loss in hospital patients with delirium. The main questions it aims to answer are: Are hearing and vision loss related to increased risk of having delirium? Do…
- Conditions
- Hearing Loss, Hearing Loss, Age-Related, Hearing Disability, Delirium
- Trial name
- SHIELD (NCT06176625)
- Testing
- Communication Signage, Amplifier Use
- Where
- United States
- Volunteers
- 1,543 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Age Related Macular Degeneration
Study of WA-NG Telescope Prosthesis in Patients With End-stage Age-related Macular Degeneration
This is a pilot study to evaluate the safety of the Model WA-NG telescope prosthesis in patients with bilateral moderate to profound central vision impairment due to end-stage age-related macular degeneration.
- Trial name
- NCT01731964
- Testing
- Telescope prosthesis, WA-NG Telescope Prothesis
- Where
- Israel
- Sponsor
- VisionCare, Inc.
Gait Disorders, Neurologic, Gait Disorders in Old Age
ExerG: Video Game-based Physical Cognitive Training for Patients: a Usability Study
Video game-based training programs, in the following referred to as "exergames" are an innovative digital training approach to simultaneously train physical and cognitive functions and increase training motivation for various…
- Conditions
- Gait Disorders, Neurologic, Gait Disorders in Old Age, Gait Disorder, Sensorimotor, Balance; Distorted
- Trial name
- ExerGetic (NCT05967078)
- Testing
- ExerG
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Frank Behrendt
Pathological Myopia
Efficacy and Safety of Ranibizumab in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia
This study is designed to evaluate the efficacy and safety of two different dosing regimens of 0.5 mg ranibizumab given as intravitreal injection in comparison to verteporfin PDT in patients with visual impairment due to…
- Trial name
- NCT01217944
- Testing
- Ranibizumab, Verteporfin PDT
- Where
- 74 sites in Austria, Canada and 18 more
- Volunteers
- 277 people
- Sponsor
- Novartis Pharmaceuticals
Accidental Fall, Visual Impairment
Falls Prevention for Visually Impaired Older People
This study aims to examine the effectiveness of an intensive five day falls prevention training programme with a home evaluation and a home exercise programme, compared with a home evaluation and exercise programme alone for…
- Conditions
- Accidental Fall, Visual Impairment, Fall
- Trial name
- NCT04078529
- Testing
- 5 day falls prevention training, Home exercise programme, Environmental Assessment
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Blind Veterans UK
Mild Cognitive Impairment
Olfactory Training in Mild Cognitive Impairment
Sense of smell tends to decline in individuals with early Alzheimer's disease, typically earlier than when other senses and thinking abilities begin to decline.
- Trial name
- OTMCI (NCT06825403)
- Testing
- Olfactory Memory Training, Visual Memory Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Jeffrey Motter
Hypoxia, Altitude
Colour Vision Impairment During Acute Hypobaric Hypoxia
This study analyses the impairment of colour vision during hypobaric hypoxia in volunteers of different groups.
- Trial name
- NCT05584813
- Testing
- Hypobaric Hypoxia
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Köln
Neovascular Age-related Macular Degeneration
Study of Innovative Multimodal Imaging Biomarkers to Predict Anatomical Outcome in Naive Patients With wAMD Treated With Brolucizumab.
The purpose of this study was to identify innovative early imaging parameters as predictors of the long-term clinical response to brolucizumab in terms of fluid resolution in patients with wet Age-related Macular Degeneration…
- Trial name
- IMAGINE (NCT04774926)
- Testing
- Brolucizumab
- Where
- 20 sites in Italy
- Volunteers
- 122 people
- Sponsor
- Novartis Pharmaceuticals
Visual Impairment
Randomized Controlled Trial Evaluating an Incentive-based Community Eye-care Programme
Elderly with visual impairment (VI) who undergo community eye screening often do not attend tertiary follow-up even if significant eye diseases are detected.
- Trial name
- NCT03264885
- Testing
- Incentive Care
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Hemianopia, Visual Field Defect Following Cerebrovascular Accident
Screening and Rehabilitation of Visual Field Defects in Post-Stroke Patients
In this study, the investigators will use a wearable device capable of performing this bedside assessment to evaluate the incidence of visual field loss in post-stroke patients.
- Trial name
- SCRiCaViPS (NCT07317739)
- Testing
- Early multisensory audio-visual stimulation training, Early visual field test
- Volunteers
- 300 people
- Sponsor
- Fondazione David Chiossone - Impresa Sociale
Wet Macular Degeneration
Sub-tenon Triamcinolone Acetonide in Age-Related Macular Degeneration as Adjunct to Ranibizumab
In the Western World, Age Related Macular Degeneration (ARMD) is a leading cause of blindness. This disease was once thought to be a natural part of aging, but recent research has introduced effective treatments.
- Trial name
- STAR (NCT01249937)
- Testing
- Ranibizumab, Triamcinolone Acetonide
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Amblyopia
Early Detection and Prevention of Amblyopia and Visual Impairment Through Systematic Pediatric Vision Screening
Amblyopia, characterized by reduced visual acuity, develops in childhood due to insufficient sensory stimulation of the affected eye.
- Trial name
- FALSSE (NCT07112560)
- Testing
- Standard screening procedure for amblyopia, New amblyopia screening method using a virtual reality headset.
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Visual Impairment
Influence of Low Vision Assistive Technology on Mobility Among Visually Impaired Individuals
This study investigates the influence of low vision assistive technology (AT) on the mobility and independence of individuals with visual impairments.
- Trial name
- NCT07055646
- Testing
- Traditional Assistive Technology, Digital Assistive Technology, Combined Technology Users
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Superior University
Visual Field Defect, Peripheral, Stroke
Improving Visual Field Deficits With Noninvasive Brain Stimulation
This is a randomized, pilot interventional study in participants with visual field deficit (VFD) caused by cortical lesion. Damage to the primary visual cortex (V1) causes a contra-lesional, homonymous loss of conscious vision…
- Conditions
- Visual Field Defect, Peripheral, Stroke, Visual Impairment, Hemianopsia
- Trial name
- NCT05085210
- Testing
- transcranial random noise stimulation (tRNS), Computer Based Visual Training, Virtual Reality Based Visual Training
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Beth Israel Deaconess Medical Center
Corneal Neovascularisation
Strategies for Management of Corneal Neovascularisation
The cornea is the transparent window of the eye, which allows light to enter into the eye and also contributes to the focusing of the light rays.
- Trial name
- NCT02594423
- Testing
- Fine Needle Diathermy, Bevacizumab
- Volunteers
- 40 people
- Sponsor
- University of Nottingham
Focus: Surgical Smoke During Laparoscopic Surgery
Assessment of a New Surgical Smoke Clearing Technology in Laparoscopic Cholecystectomy
The study will examine the safety and performance of a new surgical smoke clearance system designed for use during laparoscopic surgery.
- Trial name
- Innervision (NCT01534832)
- Testing
- Innervision Surgical Smoke Removal System
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Asalus Medical Instruments Limited