Clinical trials: Visual Hallucination
Lewy Body Disease, Lewy Body Dementia
Visual Hallucinations in Lewy Body Diseases
The goal of this basic experimental study involving humans (BESH) protocol is to improve the understanding of neural mechanisms underlying visual hallucinations in Lewy Body diseases to inform future treatment developments.
- Conditions
- Lewy Body Disease, Lewy Body Dementia, Parkinson Disease, Parkinson Disease Dementia
- Trial name
- NCT07849413
- Testing
- Behavioral Tasks, MRI/MEG Scans
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Bilateral Cataract, Charles Bonnet Syndrome
Patient Reported Visual Satisfaction Following Same Day or Delayed Bilateral Cataract Surgery
Cataract is currently the leading cause of visual impairment worldwide with age being the most common cause of lenticular opacification.
- Trial name
- CatquestCBS (NCT05069753)
- Testing
- Immediate sequential bilateral cataract surgery (ISBCS), Delayed sequential bilateral cataract surgery (DSBCS)
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Charles Bonnet Syndrome
Neuroscience of Charles Bonnet Syndrome
Charles Bonnet Syndrome (CBS) is a condition in which people experience complex visual hallucinations, such as 'Acrobats balancing on bicycles' or 'Spiders crossing meals'.
- Trial name
- NCT04777630
- Testing
- None, neuroimaging
- Where
- 2 sites in United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Oxford
Parkinson's Disease, Visual Hallucinations
Role of Retina in Mechanisms of Illusions and Visual Hallucinations Observed in Idiopathic Parkinson's Disease
Parkinson's disease is characterized not only by motor symptoms but also by psycho-behavioral symptoms including Visual Hallucinations (VH) and illusions (I), that are generally associated with a severe functional impairment and…
- Trial name
- NCT03454269
- Testing
- Optical Coherence Tomography
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Clermont-Ferrand
Audio Visual Hallucinations, Neurofeedback
Rt-fMRI Neurofeedback and AH in Schizophrenia
Auditory hallucinations in schizophrenia are one of the major symptoms of this disease and a major source of psychological discomfort. They are often difficult or impossible to treat with existing methods.
- Conditions
- Audio Visual Hallucinations, Neurofeedback, Schizophrenia, Superior Temporal Gyrus
- Trial name
- NCT03504579
- Testing
- rt-fMRI neurofeedback
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Prevalence, Psychiatrist Intervention
A Trial of Patients With a Charles Bonnet Syndrome
Charles Bonnet Syndrome (CBS) is defined by the occurence of visual hallucinations (VH) in the absence of any mental disorder. Elderly patients with reduced visual acuity due to ophthalmic diseases are most affected.
- Trial name
- CBS (NCT03148249)
- Testing
- interview
- Volunteers
- 34 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Parkinson's Disease, Hallucinations, Visual
Apomorphine in Parkinson's Disease Patients With Visual Hallucinations
This randomised, double-blind, placebo-controlled trial will evaluate the efficacy of continuous apomorphine infusion compared to placebo in PD patients with visual hallucinations, inadequately controlled with clozapine and…
- Trial name
- NCT02702076
- Testing
- Apomorphine
- Where
- Netherlands
- Volunteers
- 35 people
- Sponsor
- University Medical Center Groningen
Schizophrenia, Visual Hallucination
Visual Information Processing in Schizophrenia Patients With Visual Hallucinations
Occurrence of visual hallucinations (VHs) in schizophrenia depend in part on disorders in the processing of late visual information (Top-Down).
- Conditions
- Schizophrenia, Visual Hallucination, Auditory Hallucination, False Perception
- Trial name
- SHALL (NCT03188133)
- Testing
- behavioral task : emotional priming
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Schizophrenia, Hallucinations, Auditory
fMRI-based Neurofeedback to Relieve Drug-resistant Auditory Hallucinations
The INTRUDE trial aims at assessing the efficacy of an fMRI-based neurofeedback procedure on drug-resistant auditory hallucinations.
- Conditions
- Schizophrenia, Hallucinations, Auditory, Hallucinations, Visual
- Trial name
- INTRUDE (NCT04798131)
- Testing
- Active neurofeedback procedure
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Lille
Lewy Body Dementia, Dementia With Lewy Bodies
Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder
This study seeks to evaluate the long-term safety and effectiveness of nelotanserin for the treatment of visual hallucinations (VHs) and Rapid Eye Movement (REM) Sleep Behavior Disorder (RBD) in subjects with Lewy body dementia…
- Conditions
- Lewy Body Dementia, Dementia With Lewy Bodies, Parkinson's Disease Dementia, Visual Hallucinations
- Trial name
- NCT02871427
- Testing
- Nelotanserin
- Where
- 19 sites in United States
- Volunteers
- 80 people
- Sponsor
- Axovant Sciences Ltd.
Parkinson's Disease
Cholinesterase Inhibitors to Slow Progression of Visual Hallucinations in Parkinson&Apos;s Disease
Rationale: Visual hallucinations (VH) are the most common non-motor symptoms in Parkinson's disease (PD). As an independent predictor for cognitive decline and nursing home placement they form an important disability milestone in…
- Trial name
- CHEVAL (NCT01856738)
- Testing
- Rivastigmine
- Where
- 4 sites in Netherlands
- Volunteers
- 91 people
- Sponsor
- Amsterdam UMC, location VUmc
Visual Hallucinations, Psychotic Disorders
Cognitive Therapy for Distressing Visual Hallucinations: A Pilot Study
The study is a pilot study of Cognitive therapy for people with psychosis who have distressing visual hallucinations. The aim is to evaluate whether this is an acceptable, feasible and effective treatment.
- Trial name
- NCT02782507
- Testing
- CBT for Distressing visual hallucinations
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Newcastle University
Alzheimer Disease, Cataract
Life From Vision in Alzheimer Disease
The VIVA study is focused on Alzheimer's disease patients with a low vision due to a bilateral cataract. The aim is to study cataract surgery results on patients' autonomy, behaviour, and mood.
- Trial name
- VIVA (NCT00838942)
- Testing
- Questionaries
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Schizophrenia, Schizoaffective Disorder
Feasibility Electrical Stimulation Study for Visual Hallucinations
The visual system has increasingly been recognized as an important site of injury in patients with schizophrenia and other psychoses.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- NCT04870710
- Testing
- transcranial electrical stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Beth Israel Deaconess Medical Center
Parkinson's Disease, Perception
Perception in Parkinson's Disease
The investigators plan to examine the relation of perceptual variables-basic vision, unusual perceptual experiences(including but not limited to visual hallucinations)-to relevant functional variables such as cognition, mood, and…
- Conditions
- Parkinson's Disease, Perception, Visual Hallucination
- Trial name
- NCT05483036
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Boston University Charles River Campus
Lewy Body Dementia, Visual Hallucinations
Study Evaluating Nelotanserin for Treatment of Visual Hallucinations in Subjects With Lewy Body Dementia
This study seeks to evaluate safety and efficacy of Nelotanserin for the treatment of visual hallucinations in subjects with Lewy body dementia.
- Trial name
- NCT02640729
- Testing
- Nelotanserin
- Where
- 10 sites in United States
- Volunteers
- 30 people
- Sponsor
- Axovant Sciences Ltd.
Parkinson Disease
Pimavanserin for Sleep in Parkinson Disease
This pilot, self-control study is for patients with Parkinson's Disease (PD) psychosis (e.g., visual hallucinations, delusions) and sleep problems.
- Trial name
- NCT05796167
- Testing
- Pimavanserin
- Where
- United States
- Sponsor
- State University of New York - Downstate Medical Center
Charles Bonnet Syndrome
Charles Bonnet Syndrome in Low Vision Patients
Among patients with chronic and degenerative ocular diseases that cause visual limitations, the presence of Charles Bonnet Syndrome (CBS) may be detected as a comorbidity.
- Trial name
- CBS (NCT07563101)
- Where
- Italy
- Volunteers
- 640 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS