Clinical trials: Visual Functions
Macular Pucker, Macular Hole
Membrane Blue Versus Infracyanine Green
To compare possible toxicities of membrane blue and infracyanine green in vivo by macular function and peripheral visual field.
- Trial name
- NCT00555269
- Volunteers
- 30 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Retinal Vein Occlusion
Radial Optic Neurotomy in Central Retinal Vein Occlusion : a Randomized Trial
Natural evolution of severe central retinal vein occlusion with low visual acuity is very poor. A randomized clinical trial will compare troxerutin and platelet anti-aggregating agents (drug treatment) versus surgery and drug…
- Trial name
- OVCR (NCT00379223)
- Testing
- vitrectomy with radial optic neurotomy
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Bordeaux
Dry Eye Disease (DED)
Randomized Single Center Study to Evaluate Tolerability, Symptoms, and Visual Functional Outcomes With the Use of OTC Lubricating Eye Drops in Subjects With Dry Eye Disease
A study to evaluate the effect of over- the- counter (OTC) lubricating eye drops on tolerability, symptoms and visual outcomes in patients with dry eye disease (DED)
- Trial name
- NCT07676084
- Testing
- Preservative Free Polyethylene glycol 400 0.25%, Propylene Glycol (0.6%), Carboxymethylcellulose sodium 0.5%, Glycerin 1.0%, Polysorbate 80 0.5%
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Andover Research Eye Institute
Bilateral Cataract, Charles Bonnet Syndrome
Patient Reported Visual Satisfaction Following Same Day or Delayed Bilateral Cataract Surgery
Cataract is currently the leading cause of visual impairment worldwide with age being the most common cause of lenticular opacification.
- Trial name
- CatquestCBS (NCT05069753)
- Testing
- Immediate sequential bilateral cataract surgery (ISBCS), Delayed sequential bilateral cataract surgery (DSBCS)
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cataract
Assessment of Visual Function and Optics in Intraocular Lenses
The main objective of this research is to assess visual function and optical performance of CE marked, implanted intraocular lenses to understand the individual factors that affect their performance and how these may be improved…
- Trial name
- NCT01654159
- Testing
- Monofocal IOL, Multifocal IOL, Toric IOL
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Aston University
Autism Spectrum Disorder, Visual Function
Characteristics of Eye Diseases in Children and Adolescents With Autism Spectrum Disorders and the Effect of Corresponding Treatment on the Quality of Life of Children and Adolescents With Autism and Their Caregivers
This study mainly investigated the incidence of eye diseases in children with autism spectrum disorder(ASD) in Tianjin area, and analyzed related risk factors, so as to raise attention to eye diseases in children with ASD.
- Trial name
- NCT06122519
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Respiratory-Gated Imaging Techniques
Functional Respiratory Imaging After Neostigmine or Sugammadex
The use of neuromuscular blocking agents (NMBAs) is still associated with postoperative pulmonary complications. The investigators rely on acceleromyography (AMG) of a peripheral nerve/muscle to assess the patients' breathing…
- Trial name
- FRINeoS (NCT02284412)
- Testing
- Neostigmine, Sugammadex, Water for injection
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- Onze Lieve Vrouw Hospital
Knee Osteoarthritis (Knee OA), OA
Kinesiophobia and Its Impact on Pain and Function in Knee Osteoarthritis
Knee osteoarthritis (OA) is the most common chronic joint disorder, especially in older adults, and is a leading cause of pain, disability, and reduced quality of life.
- Conditions
- Knee Osteoarthritis (Knee OA), OA, Kinesiophobia
- Trial name
- KinesiOA (NCT07161895)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara Training and Research Hospital
Diabetes (DM), Diabetes Complication
Feasibility of Home Monitoring of Visual Function in DR
Diabetes is a serious condition where patients can develop complications in their body including their eyes which can lead to sight loss.
- Conditions
- Diabetes (DM), Diabetes Complication, Diabetes (Insulin-requiring, Type 1 or Type 2), Diabetic Retinopathy (DR)
- Trial name
- NCT07386613
- Testing
- Okko Health App
- Where
- 3 sites in United Kingdom
- Volunteers
- 55 people
- Sponsor
- Queen's University, Belfast
Knee Osteoarthritis, Visual Rehabilitation
Effects of Visual and Vestibular Rehabilitation in Individuals With Knee Osteoarthritis
This study aims to investigate the effects of visual rehabilitation and vestibular rehabilitation added to conventional physiotherapy on postural stability, pain, and functional status in individuals with knee osteoarthritis.
- Conditions
- Knee Osteoarthritis, Visual Rehabilitation, Vestibular Rehabilitation, Postural Stability
- Trial name
- NCT07888920
- Testing
- Conventional Physiotherapy, Visual Rehabilitation, Vestibular Rehabilitation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul Aydın University
Myopia
Comparison of LASIK and SBK
The objective of the study is to compare clinical outcomes from LASIK and SBK using FDA-approved laser technology on the same patient
- Trial name
- NCT00714363
- Testing
- LASIK, SBK
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Utah
Focal Lesions, Focal Brain Lesion
Attention and Visual Perception
The NIMH is conducting studies aimed at gaining a better understanding of the areas of the brain that are involved in different types of mental processes.
- Trial name
- NCT00111293
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Chronic Sinusitis
The Effect of Tranexamic Acid on Intraoperative and Post-Operative Bleeding in Functional Endoscopic Sinus Surgery
Sinus surgery is a common, day surgery procedure performed by general and subspecialty trained otolaryngologists. In most cases, this is a safe surgery with a low incidence of complications.
- Trial name
- NCT00671281
- Testing
- Tranexamic acid
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- University of Calgary
Myopia
Comparison of Conventional and Custom Photorefractive Keratectomy (PRK)
The study objective is to compare the clinical outcomes using wavefront guided PRK with iris registration and conventional laser PRK using FDA-approved laser technology on the same patient.
- Trial name
- NCT00713856
- Testing
- Custom PRK with iris registration, Conventional PRK
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Utah
Parkinson's Disease
Attentional Performance in Parkinson Disease
Background: Parkinson Disease (PD) is a nervous system disorder that affects movement. Dopamine is an important neurotransmitter in the brain. As PD progresses, there is less and less dopamine in the brain.
- Trial name
- NCT04428931
- Where
- United States
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dysphotopsia, Posterior Capsule Opacification
Clinical Evaluation of Low Contrast Visual Performance and Low Light Phenomena in Patients With Various Intraocular Lens Implants
The goal of this clinical investigation is to evaluate visual acuity and contrast sensitivity in low lighting conditions using several different testing devices, and measure nighttime side effects of intraocular lens (IOL)…
- Conditions
- Dysphotopsia, Posterior Capsule Opacification, Visual Acuity, Visual Function
- Trial name
- NCT07213167
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Dr. Daniel H. Chang, MD
Osteoporotic Vertebral Compression Fractures, Lung Function
Osteoporotic Vertebral Compression Fractures: Can Kyphoplasty Improve Lung Function? A Prospective Evaluation
Patients with vertebral fractures often have problems to straighten and as a consequence of impaired lung ventilation that leads to a impaired lung function.
- Trial name
- NCT01609712
- Testing
- Radiofrequency Kyphoplasty
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bonn
Cognitive Function, Academic Performance
Effect of Omega-3 LCPUFA Intervention on Learning, Cognition, Behaviour and Visual Processing.
The brain is primarily developed in the third trimester of pregnancy, but continues maturing through the late twenties, especially the prefrontal cortex.
- Conditions
- Cognitive Function, Academic Performance, Mental Health
- Trial name
- NCT02240264
- Testing
- Krill oil capsules
- Where
- 17 sites in Netherlands
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Open University
Acute Demylelinating Optic Neuritis
Fingolimod (FTY720) in Acute Demyelinating Optic Neuritis (ADON)
To evaluate the efficacy and safety of fingolimod 0.5mg versus placebo in patients with suspected acute demyelinating optic neuritis (ADON) receiving standard steroid treatment
- Trial name
- NCT01757691
- Testing
- Fingolimod 0.5mg/daily
- Where
- 2 sites in United States, Spain
- Volunteers
- 2 people
- Sponsor
- Novartis Pharmaceuticals
Pituitary Adenoma, Visual Impairment
Clinical Study of Structural and Functional Evaluation of the Visual Pathway
Sellar area tumors such as pituitary adenoma, craniopharyngioma and meningioma, etc, commonly lead to visual impairment symptoms.
- Conditions
- Pituitary Adenoma, Visual Impairment, Sellar Tumor, Neuroimaging
- Trial name
- NCT03591315
- Testing
- resting state fMRI, visual tasking state fMRI, diffusion tensor imaging
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University