Clinical trials: Visual Acuity
CLN3
Study With Batten-1 (Miglustat Liquid Formulation) to Treat Ceroid Lipofuscinosis Neuronal 3 (CLN3) Disease
The goal of this open-label, single-arm, multicenter study is to assess the efficacy and safety of Batten-1 (oral liquid formulation of miglustat) (15 mg/kg up to 600 mg/day) in approximately 27 pediatric subjects with CLN3…
- Trial name
- NCT07882290
- Testing
- Miglustat oral liquid formulation (250 mg/mL)
- Where
- 10 sites in United States, Denmark and 6 more
- Volunteers
- 27 people
- Sponsor
- Beyond Batten Disease Foundation
Visual Acuity, Comfort
Senofilcon A Investigational Manufacturing Process
To evaluate the impact of a new contact lens hydration process
- Conditions
- Visual Acuity, Comfort, Overall Vision
- Trial name
- NCT01951703
- Testing
- senofilcon A
- Where
- 4 sites in United States
- Volunteers
- 136 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity at Near, Accuracy of Accommodation
The Effect of Bifocals in Children With Down Syndrome
Visual acuity at near improves in children with Down syndrome using bifocals
- Conditions
- Visual Acuity at Near, Accuracy of Accommodation, Prevention of Strabismus, Task Readiness
- Trial name
- NCT02241356
- Testing
- bifocals, single vision glasses
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Radboud University Medical Center
Visual Impairment
Cell Phone Application for Vision Assessment
The purpose of this study is to evaluate how visual acuity assessed with Peek Acuity (a cell phone application to check visual acuity) among preschool and school-aged children 3 to less than18 years of age (1) compares to the…
- Trial name
- NCT03212222
- Testing
- Peek Acuity, Standard Visual Screening
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Duke University
Congenital Cataract
Relationship of Retinal and Visual Cortex Structure and Visual Acuity After Congenital Cataract Surgery
To evaluate the influence of the visual acuity after congenital surgery on the retinal and visual cortex structure.
- Trial name
- NCT04976608
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Wenzhou Medical University
Visual Acuity, Refractive Errors
Pre-symptomatic Screening of Visual Acuity in Pre-school Students
The present research process is a prospective, non-interventional clinical study that will be conducted -under the auspices of the Democritus University of Thrace (DUTH)- in the pre-school students of the city of Alexandroupolis…
- Conditions
- Visual Acuity, Refractive Errors, Low Vision, Vision Disorders
- Trial name
- NCT05835193
- Testing
- Diagnostic Test: Distance Visual Acuity Examination
- Where
- Greece
- Volunteers
- 1,098 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Macular Edema
Comparison of the Effects of Bevacizumab Before vs After Pattern Panretinal Photocoagulation
Compare the effect of an intravitreal injection of bevacizumab previous or posterior of panretinal laser photocoagulation (PRLP) with a pattern laser; to prevent and reduce diabetic macular edema (DME) in patients with…
- Trial name
- NCT00804206
- Testing
- bevacizumab
- Where
- Mexico
- Volunteers
- 15 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Visual Acuity
Clinical Performance of Three Daily Disposable Silicone Hydrogel Contact Lenses
This is a subject-masked, randomized, prospective, bilateral, 3x3 crossover dispensing clinical investigation to assess the clinical performance of a new lens type comparison.
- Trial name
- NCT06778057
- Testing
- Test Lens 1, Test Lens 2, Test Lens 3
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Assessment of Contact Lens Wettability Using Wavefront Aberrometry
This study will test the feasibility that differences in contact lens wettability can be measured with a wavefront sensor.
- Trial name
- NCT02349438
- Testing
- senofilcon A, lotrafilcon B
- Where
- Australia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Investigation of Visual Acuity in Contact Lens Wearers After Instillation of a Lipid- Based Lubricating Eye Drop
This is a single visit, randomized, double masked, bilateral, non-dispensing, 2×2 crossover study to assess visual acuity.
- Trial name
- NCT06131476
- Testing
- Blink® Tears eye drops, Investigational lipid eye drops
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Diabetic Macular Edema
Brolucizumab Efficacy and Safety Single-Arm Descriptive Trial in Patients With Persistent Diabetic Macular Edema
The goal of this clinical trial is to evaluate the efficacy of brolucizumab 6 mg in Chinese patients with persistent diabetic macular edema (DME). It will also learn about the safety of brolucizumab 6 mg.
- Trial name
- BEST (NCT06498050)
- Testing
- intravitreal injection of Brolucizumab 6 mg in study eye
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Guangdong Provincial People's Hospital
Visual Acuity
Effect of Action Video Games and Stroboscopic Glasses on Dynamic Visual Acuity.
The study aims to observe the possible improvement of performance in dynamic visual acuity (DVA), in terms of speed and trajectory, comparing training using action video games and strobe glasses.
- Trial name
- NCT05956938
- Testing
- Stroboscopic Glasses, Action Video Game
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Politècnica de Catalunya
Dry Eye, Eye Strain
Effects of Gunnar Computer Glasses on Viewing Comfort and Performance
The proposed study aims to test if Gunnar computer glasses provide any advantages, in comparison to no glasses, on the following aspects in computer-related office work: Any enhancement on the visual performance of the basic…
- Conditions
- Dry Eye, Eye Strain, Visual Acuity, Color Perception
- Trial name
- NCT02925884
- Testing
- Gunnar OTC Glasses
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Pacific University
Branch Retinal Vein Occlusion, Macular Edema
Ranibizumab for Macular Edema Secondary to Branch Retinal Vein Occlusion in Patients With Fair Vision
The purpose of this study is to determine the effect of ranibizumab for the treatment of macular edema (ME) secondary to branch retinal vein occlusion (BRVO) in patients with initial fair visual acuity.
- Trial name
- RVOFV (NCT01795209)
- Testing
- Ranibizumab, Rescue laser
- Where
- 2 sites in South Korea
- Volunteers
- 19 people
- Sponsor
- Seoul National University Bundang Hospital
Visual Acuity, Visual Disturbance
Intra Ocular Pressure During Robotic Prostatectomy
Our goal is to study the relationship between intraocular pressure during robotic prostatectomy surgery and visual deficiencies/vision loss after surgery.
- Conditions
- Visual Acuity, Visual Disturbance, Intraocular Pressure
- Trial name
- NCT00369057
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Weill Medical College of Cornell University
Diabetic Retinopathy
Effects of a Therapy With INTRAVIT® Tablets in Patients With Diabetic Retinopathy
Evaluation of the effect of a therapy with INTRAVIT® tablets, on retinal edema considering also the central retinal sensitivity (Microperimetry) and the visual acuity in course of diabetic retinopathy.
- Trial name
- NCT04742829
- Testing
- INTRAVIT ®
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Molise
Visual Acuity
Evaluation of Electronic LogMar Visual Acuity and Contrast Sensitivity in a Population of Contact Lens Wearers
This is a bilateral, non-dispensing, randomized, cross-over, single-masked study. There are a total of 3 visits where all study endpoints will be measured in all subjects at baseline with habitual lenses and under the two testing…
- Trial name
- NCT03222037
- Testing
- senofilcon A, Control
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Age - Related Macular Degeneration (AMD)
Study to Assess Best Corrected Visual Acuity (BCVA) in Patients With Neovascular Age-Related Macular Degeneration (AMD) Who Are Administered VEGF Trap-Eye (Intravitreal Aflibercept Injection)
This is a phase 4, open-label, single arm, multicenter, clinical study in patients with neovascular AMD designed to evaluate the efficacy and safety of Intravitreal Aflibercept Injection (IAI) administered over 2 years , and to…
- Trial name
- RE-VIEW (NCT01722045)
- Testing
- Intravitreal Aflibercept Injection (IAI)
- Where
- 49 sites in United States
- Volunteers
- 154 people
- Sponsor
- Regeneron Pharmaceuticals
Diabetic Macular Edema (DME)
Comparison of Bevacizumab and Aflibercept in Treatment of Diabetic Macular Edema
Diabetic macular edema is a frequent complication of long-standing diabetes mellitus in which fluid leaks into the central part of the retina (macula), leading to reduced vision.
- Trial name
- NCT07338097
- Testing
- Aflibercept (2.0 mg), Bevacizumab
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- CMH Multan Institute of Medical Sciences
Intraocular Lens
Distance and Intermediate Visual Acuity in Patients With Implanted Monofocal Negative Aspheric Intraocular Lens
To get the visual outcomes for distance and intermediate and binocular defocus curve in patients with implanted monofocal intraocular lens Clareon (IOL; model SY60CL; Alcon Vision LLC) at 3 months after the surgery.
- Trial name
- CLAINT (NCT05697978)
- Testing
- Monofocal intraocular lens Clareon (Alcon LLC)
- Where
- 3 sites in Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Faculty Hospital Kralovske Vinohrady