Clinical trials: Vision Disorders
Open-angle Glaucoma
Efficacy and Safety of XEN® Gel Stent and Post-operative Management in Patients With Open Angle Glaucoma
To evaluate the efficacy of postoperative management with 5-fluorouracil injections after XEN Gel Stent implantation.
- Trial name
- NCT03904381
- Testing
- 5-fluorouracil, Transconjunctival needling, Transconjunctival revision
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Wroclaw Medical University
Low Back Pain, Visual Impairment
Development of a Tele-Physiotherapy Tool for the Early Management of Muskuloskeletal Pain in People With Visual Impairement (TeleEDxPhysio)
Chronic NonSpecific Low Back Pain (CNSLBP) is a common musculoskeletal condition often resulting in physical inactivity and disability.
- Trial name
- TeleEDxPhysio (NCT05478200)
- Testing
- physical exercise, Manual therapy
- Where
- 2 sites in Spain
- Volunteers
- 128 people
- Sponsor
- Escuela Universitaria de Fisioterapia de la Once
Craniofacial Differences
Positive Exposure: A Photography and Video Intervention for Individuals With Craniofacial Differences
This study will describe the use of an intervention, developed by an organization called Positive Exposure, to improve self-perceptions among adolescents and young adults who may encounter the stigma, or negative effect, of…
- Trial name
- NCT00340964
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Keratoconus, Glaucoma
Optic Nerve Head Structural Response to IOP Elevation in Patients With Keratoconus
The mechanism by which vision loss in glaucoma occurs is still unknown, but it is clear that increased Intraocular Pressure (IOP) is a major risk factor.
- Trial name
- NCT03560609
- Testing
- Ophthalmodynamometer, Goldmann applanation tonometer, Pentacam
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- NYU Langone Health
SUSAC's Syndrome, Encephalopathy
Epidemiological, Clinical and Etiological Features of SUSAC's Syndrome
SUSAC's Syndrome (SS) is characterized by the clinical triad of encephalopathy, hearing loss, and retinal artery branch occlusions.
- Conditions
- SUSAC's Syndrome, Encephalopathy, Hearing Loss, Retinal Artery Branch Occlusions
- Trial name
- CARESS (NCT01481662)
- Testing
- Diffusion tensor magnetic resonance imaging of the brain
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Primary Angle Closure Glaucoma
Comparison of Phaco Surgery With Goniosynechialysis Versus Trabeculectomy in Glaucoma Treatment
The goal of this clinical trial is to learn whether phacoemulsification combined with goniosynechialysis (Phaco-GSL) is as effective and safe as trabeculectomy in treating patients with primary angle-closure glaucoma.
- Trial name
- NCT06952153
- Testing
- Phacoemulsification with Goniosynechialysis, Trabeculectomy with 5FU
- Where
- Vietnam
- Volunteers
- 82 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Progressive Supranuclear Palsy
Administration of GV1001 for the Treatment of Progressive Supranuclear Palsy Who Completed Study GV1001-PSP-CL2-011
The study will be conducted by the Sponsor to evaluate Twelve-months Long-Term Safety and Efficacy of GV1001 (1.12 mg) administered subcutaneously as a treatment for Progressive Supranuclear Palsy(PSP).
- Trial name
- NCT06235775
- Testing
- GV1001 1.12mg
- Where
- 5 sites in South Korea
- Volunteers
- 67 people
- Sponsor
- GemVax & Kael
Amblyopia
Efficacy of Intermittent Occlusion Therapy Glasses for Amblyopia
This study is designed to evaluate the effectiveness of a novel amblyopia treatment - Intermittent occlusion therapy (IO-therapy) glasses (AmblyzTM) in treating severe amblyopia.
- Trial name
- NCT02687581
- Testing
- IO-therapy Glasses, patch
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Salus University
Macular Degeneration
Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration (AMD)
This study is a phase III, double-masked, randomized, study of the efficacy and safety of VEGF Trap-Eye in patients with neovascular age-related macular degeneration.
- Trial name
- VIEW 2 (NCT00637377)
- Testing
- Ranibizumab, Aflibercept Injection (EYLEA, VEGF Trap-Eye, BAY86-5321)
- Where
- 189 sites in Argentina, Australia and 24 more
- Volunteers
- 1,240 people
- Sponsor
- Bayer
Intraocular Pressure, Delivery
The Effect of Labor on Intraocular Pressure Fluctuation in Healthy Eyes
Glaucoma is a multifactorial disease, an important risk factor of which is increased intraocular pressure. Fluctuations in intraocular pressure are often associated with vaginal birth, although intraocular pressure during active…
- Trial name
- ELIPFHE (NCT06016712)
- Testing
- SENSIMED Triggerfish Eye Lenses
- Where
- Czechia
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Non-proliferative Diabetic Retinopathy
A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Non-proliferative Diabetic Retinopathy (NPDR)
This Phase 3 Study will evaluate the efficacy and safety of KSI-301 in participants with moderately severe to severe non-proliferative diabetic retinopathy (NPDR).
- Trial name
- GLOW (NCT05066230)
- Testing
- KSI-301
- Where
- 61 sites in United States, Czechia and 5 more
- Volunteers
- 253 people
- Sponsor
- Kodiak Sciences Inc
Sleep Apnea, Glaucoma
Long-term Observation of Ophthalmic Changes in Patients With Obstructive Sleep Apnea
The ophthalmic changes during long-lasting sleep apnea are lacking in description and assessment. The investigators intend to observe patients for a long time and observe if the changes in eye tissues are progressing over the…
- Conditions
- Sleep Apnea, Glaucoma, Ocular Hypertension
- Trial name
- NCT03928665
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Wroclaw Medical University
Optic Neuritis
Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)
The main purpose of this study is to assess clemastine as a remyelinating agent in patients with acute optic neuritis.The study will also evaluate the tolerability of clemastine, originally approved as first-generation…
- Trial name
- ReCOVER (NCT02521311)
- Testing
- Clemastine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, San Francisco
Schizophenia Disorder, Virtual Reality
Virtual Reality for Visual Perception on Schizophrenia
Researchers have stated in the literature that visual perception is negatively affected in schizophrenia. In recent years, virtual reality interventions have become popular in the treatment of schizophrenia.
- Conditions
- Schizophenia Disorder, Virtual Reality, Visual Perception
- Trial name
- NCT06718556
- Testing
- Virtual reality, Client-centered
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Glaucoma Open-Angle Primary
OCTA Study of Choroidal Vasculature in Open Angle Glaucoma Patients
The aim of the present study was to examine and measure SFCT and CCVD using respectively EDI-OCT and OCTA in preperimetric and advanced glaucomatous eyes, in order to shed light on the vascular pathogenesis of glaucoma disease.
- Trial name
- NCT05455567
- Testing
- OCTA
- Where
- Italy
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Federico II University
Amblyopia
Increasing Patching for Amblyopia in Children 3 to < 8 Years Old
This study is designed to evaluate the effectiveness of increasing prescribed patching treatment from 2 to 6 daily hours after visual acuity has stabilized with initial treatment and amblyopia is still present.
- Trial name
- ATS15 (NCT00945100)
- Testing
- Eye Patch
- Where
- 2 sites in United States
- Volunteers
- 169 people
- Sponsor
- Jaeb Center for Health Research
Visual Impairment, Macular Edema
A Clinical Study in Current Medical Practice of the Efficacy and Safety of Ranibizumab 0.5mg in Diabetic Patients Presenting a Visual Impairment Due to Macular Edema
The purpose of this study is to evaluate the proportion of patients with a 10 letters gain on Best Corrected Visual Acuity (BCVA) at 6 months in current medical practice.
- Trial name
- LUDIC (NCT01315275)
- Testing
- Ranibizumab
- Where
- 43 sites in France
- Volunteers
- 394 people
- Sponsor
- Novartis Pharmaceuticals
Glaucoma
Blood Flow Regulation in Glaucoma
Glaucoma is one of the leading causes for blindness in industrialized countries. It is characterized by a progressive loss of retinal ganglion cells, morphological changes in the optic nerve head and a characteristic loss of…
- Trial name
- NCT02292381
- Testing
- Isometric exercise
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
ADHD, Convergence Insufficiency
Study of Eyes and Attention Deficit (SEAD)
Attention-Deficit Hyperactivity Disorder (ADHD) is considered to be one of the most prevalent chronic health conditions in children. It affects between 4% and 12% of young children.
- Conditions
- ADHD, Convergence Insufficiency, Accommodative Insufficiency
- Trial name
- NCT00472511
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Primary Open Angle Glaucoma, Obstructive Sleep Apnea
Glaucoma Respsosne to Lifestyle Corrections in Sleep Apnea
glaucoma is prevalent among obstructive sleep apnea (OSA). contnous passive airway pressure is main treatment of OSA. lifestyle corrections also recommended
- Conditions
- Primary Open Angle Glaucoma, Obstructive Sleep Apnea, Obesity
- Trial name
- NCT07447011
- Testing
- lifetyle corrections and CPAP, CPAP
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University