Clinical trials: Vision Correction
Myopia
Pilot Study of Neurovision to Improve Vision and Slow Myopia Progression in Children With Myopia
This is a pilot study to assess the effectiveness of Neurovision treatment in the improvement of vision in children being under-corrected and to assess the effectiveness of Neurovision treatment in slowing down myopia progression…
- Trial name
- NCT00348218
- Testing
- NeuroVision
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore National Eye Centre
Presbyopia
Safety and Efficacy of an Intrastromal Transform™ Corneal Allograft (TCA) for Presbyopia Correction
The objective of this clinical study is to evaluate the safety and effectiveness of intrastromal implantation of the Allotex TransForm corneal allograft (TCA) for improving near vision in presbyopic subjects.
- Trial name
- NCT03671135
- Testing
- TCA Intrastromal Inlay
- Where
- 4 sites in Belgium, Ireland and 1 more
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Allotex, Inc.
Refractive Errors
Clinical Evaluation of a Daily Wear Monthly Replacement Silicone Hydrogel Lens
The purpose of this clinical study is to evaluate the safety and effectiveness of an investigational soft contact lens compared to a commercially available soft contact lens when worn for daily wear and replaced monthly.
- Trial name
- NCT04178720
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 8 sites in United States
- Volunteers
- 119 people
- Sponsor
- Alcon Research
Cerebral Visual Impairment, Refractive and Accommodative Disorders
Babies in Glasses; a Feasibility Study.
This is a feasibility study to begin investigating the possibility that early use of near vision glasses will improve vision in infants at risk of Cerebral Visual Impairment (CVI), leading to further improvement in other areas of…
- Conditions
- Cerebral Visual Impairment, Refractive and Accommodative Disorders, Hypoxic-Ischemic Encephalopathy, Premature Birth
- Trial name
- BiG (NCT05048550)
- Testing
- Near vision spectacles
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Myopia, Refractive Errors
A Clinical Trial to Evaluate the Vision Correction Safety and Efficacy of MSiHy Silicone Hydrogel Soft Contact Lens
This is a prospective, randomized, double-blind, parallel, active-controlled, multi-center clinical study. The purpose is to evaluate the safety and effectiveness wearing "MSiHy Silicone Hydrogel Soft Contact Lens".
- Trial name
- NCT06716385
- Testing
- MSiHy Silicone Hydrogel Soft Contact Lens, Monthly Silicone Hydrogel Contact Lenses (oA)
- Where
- 3 sites in Taiwan
- Volunteers
- 134 people
- Sponsor
- Visco Vision Inc.
Strabismus
Basic Intermittent Exotropia and Risk Factors for Postoperative Overcorrection and Under Correction
To evaluate preoperative risk factors for overcorrection and undercorrection following surgery for basic intermittent exotropia such as axial length of the globe, refractive error, age and sex
- Trial name
- NCT03153423
- Testing
- Strabismus surgery
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Minia University
Presbyopia
PROductivity Study of Presbyopia Elimination in Rural-dwellers (PROSPER)
This trial seeks to establish, using a randomized, controlled design, the impact of near eyesight correction on the productivity of presbyopic agricultural workers in India, as measured by weight of tea picked.
- Trial name
- PROSPER (NCT03228199)
- Testing
- Intervention group, Control Group
- Where
- India
- Volunteers
- 751 people, healthy volunteers welcome
- Sponsor
- Congdon Nathan
Psychological Stress, Anesthesia
RELIEF OF PSYCHOEMOTIONAL STRESS USING XENON SEDATION
The goal of this clinical trial is to propose for implementation and evaluate the effectiveness of xenon sedation for the relief of psychoemotional stress disorder before the operation of refractive laser vision correction…
- Conditions
- Psychological Stress, Anesthesia, Anxiety, Xenon
- Trial name
- NCT06080100
- Testing
- Xenon, premedication hydroxyzine 25 mg
- Where
- Russia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Myopia
A Singapore Study to Assess How Neurovision Improve the Vision of Adults With Low to Moderate Myopia
To evaluate the efficacy of NeuroVision NVC vision correction technology to improve the vision of subjects with Low and Moderate Myopia in Asian eyes in Singapore
- Trial name
- NCT00348075
- Testing
- Neurovision
- Where
- Singapore
- Sponsor
- Singapore National Eye Centre
Presbyopia
An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-2)
This is a 4-visit, multi-center, randomized, double-masked, vehicle-controlled study evaluating the safety and efficacy of CSF-1 in the temporary correction of presbyopia.
- Trial name
- NEAR-2 (NCT04599972)
- Testing
- CSF-1, Vehicle
- Where
- 18 sites in United States
- Volunteers
- 304 people
- Sponsor
- Orasis Pharmaceuticals Ltd.
Refractive Errors
Clinical Evaluation of a Daily Wear Frequent Replacement Silicone Hydrogel Lens
The purpose of this clinical study is to demonstrate the safety and performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn in a daily wear modality.
- Trial name
- NCT03920280
- Testing
- LID015385 contact lenses, Comfilcon A soft contact lenses, CLEAR CARE
- Where
- 8 sites in United States
- Volunteers
- 120 people
- Sponsor
- Alcon Research
Vision Loss
First-Sight Refractive Error Correction in the Developing World
The aim of this study is to test the efficacy of the First-Sight refractive kit designed to provide refractive correction of simple hyperopia, myopia and astigmatism with autorefraction.
- Trial name
- NCT01598818
- Where
- 2 sites in United States, Haiti
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Dry Eye
A Prospective, Randomized, Double-Masked, Single Center, Clinical Comparison of the Use of Systane Ultra in the Management of Dry Eyes in Bilateral Eyes
The primary objective of this study is to compare two post operative drop regimens for the management of dry eye and control of healing using FDA-approved ophthalmic solutions.
- Trial name
- NCT00781092
- Testing
- Systane Ultra, Bausch and Lomb Sensitive Eyes
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Durrie Vision
Post Laser Vision Correction Pain and Discomfort
Laser Vision Correction Use of an Eye Shield for Maintaining Vision and Mitigating Pain
The purpose of this research is to determine if an investigational thin shield can effectively reduce discomfort following Laser Vision Correction.
- Trial name
- NCT01675375
- Testing
- Eye Shield
- Where
- 5 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- FORSIGHT Vision3
Esotropia, Exotropia
Comparison of Two Treatments for Strabismus Correction: Botulinum Toxin A Associated to Surgery and Surgery Alone
Two different treatments were given to large angle horizontal strabismus (eso and exotropia) adult patients who agree to participate of the study. Inform consents were required for participants.
- Trial name
- NCT01460355
- Testing
- Botulinum Toxin Type A, saline solution
- Where
- Brazil
- Volunteers
- 23 people
- Sponsor
- University of Campinas, Brazil
Cataract and IOL Surgery, IOL Implantation
Head-to-Head Comparison of Five Enhanced Depth of Focus IOLs and One Monofocal IOL
Study Goal The goal of this clinical trial is to compare how well four different types of artificial lenses (called intraocular lenses or IOLs) help people see after cataract surgery.
- Conditions
- Cataract and IOL Surgery, IOL Implantation, Presbyopia Correction, Extended Depth of Focus
- Trial name
- AKA-Reports (NCT07051720)
- Testing
- Bilateral implantation of CT ASPHINA 409M, Bilateral implantation of TECNIS Eyhance ICB00, Bilateral implantation of AcrySof® IQ Vivity®
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Augenklinik Ahaus G + H GmbH & Co. KG
Presbyopia
PROductivity Study of Presbyopia Elimination in Rural-dwellers II
The investigators will conduct a randomized-controlled trial. The participants will be textile workers aged 35 years and above with uncorrected presbyopia who are employed by a single Indian garment manufacturer - employed by…
- Trial name
- PROSPERII (NCT04629820)
- Testing
- Spectacles
- Where
- India
- Volunteers
- 682 people
- Sponsor
- Queen's University, Belfast
Refractive Errors
Clinical Evaluation of a Silicone Hydrogel Daily Wear Monthly Replacement Contact Lens
The purpose of this clinical study is to evaluate the safety and performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn in a daily wear modality.
- Trial name
- NCT04422990
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 14 sites in United States
- Volunteers
- 158 people
- Sponsor
- Alcon Research
Nearsightedness, Farsightedness
Advanced Surface Ablation (ASA) vs Laser-Assisted In Situ Keratomileusis (LASIK)
The purpose of this combined retrospective and prospective chart review analysis is to investigate the safety, efficacy, and predictability obtained via Laser-Assisted In Situ Keratomileusis (LASIK) and Advanced Surface Ablation…
- Conditions
- Nearsightedness, Farsightedness, Astigmatism
- Trial name
- NCT00778570
- Where
- Canada
- Volunteers
- 4,000 people
- Sponsor
- Ottawa Hospital Research Institute
Presbyopia
Assessment of Near Vision Capacity in Different Light Intensities
Patients who underwent presbyopic correction with bilateral bifocal intraocular lenses implantation are supposed to have sufficient uncorrected vision capacity for activities of daily living (ADLs) that require near vision acuity…
- Trial name
- NCT03024073
- Testing
- BB-Phaco
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Democritus University of Thrace