Clinical trials: Veteran
Schizophrenia, Schizo-affective Disorder
Illness Management and Recovery for Veterans With Severe Mental Illness
The President's New Freedom Commission on Mental Health has called for a transformation of the mental health system to partner with consumers of those services in delivering effective interventions focused on recovery, and the…
- Trial name
- NCT00515671
- Testing
- Illness Management and Recovery, Problem Solving
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- VA Office of Research and Development
Lung Cancer
Co-Design and Pilot Testing of Peer-led Community Outreach to Improve Equity, Veteran-Centeredness and Uptake of Lung Cancer Screening
Co-design will be implemented to develop an innovative, Veteran-centered intervention (Vet Peer Connects program) that meets the needs of Black Veterans.
- Trial name
- VPC (NCT06389981)
- Testing
- Veterans peer connect Program
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Anxiety, Depression
Improving Obesity Self-Care Among Mentally Ill Veterans
The purpose of this study is to find out which of two programs, MH MOVE! or the enhanced usual care MOVE! program is most effective in improving participation in and completion of MOVE! among Veterans with depression, anxiety…
- Conditions
- Anxiety, Depression, PTSD, Obesity
- Trial name
- MH MOVE! (NCT02642536)
- Testing
- MH MOVE, Enhanced Usual Care
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- VA Office of Research and Development
Low Back Pain, PTSD
Care Outcomes for Chiropractic Outpatient Veterans
The primary objectives of this pilot trial are to evaluate the feasibility, safety and acceptability of an integrative care pathway that includes chiropractic care, for the coordinated care for Veterans Administration (VA)…
- Conditions
- Low Back Pain, PTSD, Depression, Anxiety
- Trial name
- COCOV (NCT03254719)
- Testing
- Study assessments
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Palmer College of Chiropractic
Fatigue, Musculoskeletal Pain
Complementary Neurosteroid Intervention in Gulf War Illnesses (GWVI)
This study will investigate the use of adjunctive pregnenolone for the following: 1. fatigue that has limited usual activity, 2. musculoskeletal pain involving 2 or more regions of the body and, 3.
- Conditions
- Fatigue, Musculoskeletal Pain, Cognitive Decline
- Trial name
- NCT01956279
- Testing
- Pregnenolone
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- VA Office of Research and Development
Opioid Use Disorder, Chronic Pain
An Adaptive Walking Intervention to Manage Chronic Pain in Veterans With Opioid Use Disorder Engaged in Opioid Agonist Treatment
Severe chronic pain and opioid use disorder (OUD) occur at significantly higher rates in Veterans compared to the general population.
- Trial name
- NCT05051644
- Testing
- Steps 2 Change (S2C), Control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Virtual Reality & D-cycloserine (DCS) for Posttraumatic Stress Disorder (PTSD)
This study proposes to evaluate the effects of D-cycloserine (DCS) combined with Virtual Reality exposure therapy in a sample of patients who developed posttraumatic stress disorder (PTSD) following either the events of September…
- Trial name
- VR-DCS (NCT00632632)
- Testing
- D-Cycloserine
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Weill Medical College of Cornell University
Physical Activity, Peer Leaders
Peer-Led Diet and Exercise Intervention
The majority of older Veterans do not meet the minimum healthy diet or physical activity recommendations, despite known benefits.
- Conditions
- Physical Activity, Peer Leaders, Diet Quality
- Trial name
- NCT04994938
- Testing
- Diet Intervention, Exercise Intervention
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Mild Traumatic Brain Injury, Posttraumatic Stress Disorders
Multifamily Group to Reduce Marital Conflict and Disability in Veterans With mTBI
This project addresses the rehabilitation and mental health needs of married combat Veterans post-deployed from Iraq or Afghanistan with a mild traumatic brain injury (mTBI) and/or significant posttraumatic stress (PTS) or…
- Conditions
- Mild Traumatic Brain Injury, Posttraumatic Stress Disorders, Depression
- Trial name
- MFG-mTBI (NCT02057081)
- Testing
- Multifamily Group for mTBI for Couples, Group Health Education (GHE)
- Where
- 3 sites in United States
- Volunteers
- 249 people
- Sponsor
- VA Office of Research and Development
Aging
Longitudinal Outcome in a Veterans Geriatric Multifactorial Falls Assessment Clinic
Objective To reduce subsequent falls following Multifactorial Falls Assessment Design: Prospective Case Control Population: Frail elderly Veteran outpatient population referred for falls assessment Methods: Prospective controlled…
- Trial name
- NCT02356211
- Testing
- Multifactorial Falls Assessment
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Powers, James S., M.D.
Irritable Bowel Syndrome, Small Intestinal Bacterial Overgrowth
Gulf War Digestive Health Study
The purposes of this study are to estimate the burden of disease due to chronic gastrointestinal illness in PG veterans, to evaluate whether Small Bowel Bacterial Overgrowth (SBBO) is associated with chronic diarrhea in PG…
- Trial name
- NCT00680836
- Testing
- Rifaximin
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- US Department of Veterans Affairs
Cerebrovascular Accident
Home-based Telehealth Stroke Care: A Randomized Trial for Veterans
The purpose of the proposed study is to examine a Tele-rehabilitation (TR) intervention that uses tele-health technology to improve outcomes of stroke patients after discharge to home.
- Trial name
- NCT00384748
- Testing
- TR intervention, In-home messaging device., Usual care
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- US Department of Veterans Affairs
Posttraumatic Stress Disorder, Tinnitus
Neurobiological Similarities of Tinnitus and PTSD
Psychiatric distress caused by PTSD may increase attention toward tinnitus, as well as perceived loudness and discomfort. It is important to understand how tinnitus-related distress and PTSD negatively interact together, in order…
- Trial name
- NCT05981391
- Testing
- resting-state functional MRI, Clinician Administered PTSD Scale for the DSM-5 (CAPS-5), Tympanometry
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Sedentary Behavior, Exercise
Multiphase Optimization Trial of Incentives for Veterans to Encourage Walking
Regular physical activity (PA) is essential to healthy aging. Unfortunately, only 5% of US adults meet guideline of 150 minutes of moderate exercise; Veterans and non-Veterans have similar levels of PA.
- Conditions
- Sedentary Behavior, Exercise, Walking, Motivation
- Trial name
- NCT04518943
- Testing
- Walking
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- VA Office of Research and Development
Impaired Fasting Glucose, Impaired Glucose Tolerance
D Vitamin Intervention in VA
This study will supplement African American male (AAM) veterans at risk for diabetes and newly diagnosed T2DM with vitamin D (low or higher dose) and evaluate whether vitamin D helps to improve early markers of diabetes.
- Conditions
- Impaired Fasting Glucose, Impaired Glucose Tolerance, Vitamin D Insufficiency
- Trial name
- DIVA (NCT01375660)
- Testing
- 50K vitamin D2
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- US Department of Veterans Affairs
Insomnia, Alcohol Use Disorder
CBT-I on Alcohol Treatment Outcomes Among Veterans
Project SAVE aims to examine the feasibility, acceptability, and initial efficacy of a CBT-I supplement to alcohol treatment of Veterans.
- Trial name
- Project SAVE (NCT03806491)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene, Alcohol Use Disorder Treatment as Usual
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Cardiovascular Disease, Hypertension
A Nurse-led Intervention to Extend the Veteran HIV Treatment Cascade for Cardiovascular Disease Prevention
The VA is the largest single provider of HIV care in the US and Veterans with HIV use significantly more healthcare services and have a 1.5-2x higher risk of atherosclerotic cardiovascular disease (ASCVD) compared to uninfected…
- Conditions
- Cardiovascular Disease, Hypertension, Care Coordination, HIV Treatment Cascade
- Trial name
- V-EXTRA-CVD (NCT04545489)
- Testing
- Intervention group, Education control group
- Where
- 4 sites in United States
- Volunteers
- 305 people
- Sponsor
- VA Office of Research and Development
Insomnia, Mental Health Disorder
Comparison of Quetiapine and Trazodone Treatment for Insomnia in Dually Diagnosed Veterans
This is a pilot comparative effectiveness study designed to determine whether trazodone is as effective as quetiapine for treatment of insomnia in veterans with a history of addiction and mental health issues.
- Conditions
- Insomnia, Mental Health Disorder, Substance Use Disorder
- Trial name
- NCT01662297
- Testing
- Quetiapine, Trazodone
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- VA Connecticut Healthcare System
Postural Balance, Accidental Falls
Improving Balance and Mobility
Falls are dangerous leading to injuries and even death. The VA has made fall prevention a priority, but effective programs only reduce falls by 30%.
- Conditions
- Postural Balance, Accidental Falls, Mobility Limitation
- Trial name
- MMBI (NCT02374463)
- Testing
- MMBI, Tai Chi
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depressive Disorder, Depression
Telephone Administered Psychotherapy for the Treatment of Depression for Veterans in Rural Areas
The purpose of this study is to examine the efficacy of telephone-administered cognitive-behavioral therapy (T-CBT) in treating major depression among veterans served by community-based outpatient clinics (CBOCs) in the Veteran's…
- Trial name
- NCT00223652
- Testing
- Telephone cognitive behavioral therapy
- Where
- 3 sites in United States
- Volunteers
- 85 people
- Sponsor
- US Department of Veterans Affairs