Clinical trials: Vestibular Disease
Ototoxic Hearing Loss, Ototoxicity, Drug-Induced
Cisplatin-induced Cochlear and Vestibular Damage in Head and Neck Cancer
The goal of this observational study is to learn about the occurrence of and to identify suitable strategies for screening and monitoring of inner ear damage in patients receiving cisplatin chemoradiotherapy for head and neck…
- Conditions
- Ototoxic Hearing Loss, Ototoxicity, Drug-Induced, Cisplatin-induced Hearing Loss, Cisplatin Ototoxicity
- Trial name
- NCT06929468
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Simon Jäger
Sensorineural Hearing Loss, Hearing Disorder
Genetic Analysis of Hereditary Disorders of Hearing and Balance
This study will try to identify the genetic causes of hereditary hearing loss or balance disorders. People with a hearing or balance disorder that affects more than one family member may be eligible for this study.
- Conditions
- Sensorineural Hearing Loss, Hearing Disorder, Vestibular Disease
- Trial name
- NCT00023049
- Where
- 2 sites in United States, Nigeria
- Volunteers
- 335 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Vestibular Schwannoma, Meniere Disease
CI Following VS Removal or Labyrinthectomy
This study is a prospective, clinical study to determine if it is safe and effective to use a cochlear implant over time in individuals undergoing removal of a vestibular schwannoma (VS), benign tumor of the hearing and balance…
- Trial name
- NCT03795675
- Testing
- Cochlear Implant
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ohio State University
Vestibular Disease
Human Visual and Vestibular Motion Perception Study
The purpose this study is to measure sensitivity to visual and vestibular or balance motion. It is hoped that the results may help researchers better understand how aging and disease affect motion perception.
- Trial name
- NCT04142697
- Testing
- Heading direction adaptation
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Persistent Postural-perceptual Dizziness
Prevalence and Diagnosis of Persistent Postural-perceptual Dizziness
Persistent Postural-Perceptual Dizziness (PPPD) is a chronic vestibular disorder characterized by persistent symptoms of dizziness or unsteadiness that lasts for three months or longer.
- Trial name
- NCT07855081
- Testing
- Comprehensive Audio-Vestibular Evaluation
- Volunteers
- 50 people
- Sponsor
- Sohag University
Children, Only, Vestibular Disorder
Vestibular and Postural Function in Children Suspected of Balance Disorders
The goal of this prospective cohort study is to investigate the vestibular function in children suspected of balance disorders, and to follow up on their balance progressions after rehabilitation.
- Conditions
- Children, Only, Vestibular Disorder, Vestibular Function Disorder, Development Delay
- Trial name
- VASIC (NCT06229704)
- Testing
- video Head Impulse Test, Cervical Vestibular Evoked Myogenic Potential, Ocular Vestibular Evoked Myogenic Potential
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Gødstrup Hospital
Children, Only, Vestibular Disorder
Vestibular and Postural Function in an Unselected Group of Children With Sensorineural Hearing Loss
The goal of this prospective cohort study is to investigate the vestibular function in children with unilateral or bilateral sensorineural hearing loss.
- Conditions
- Children, Only, Vestibular Disorder, Vestibular Function, Sensorineural Hearing Loss
- Trial name
- VASIC (NCT06229717)
- Testing
- video Head Impulse Test, Cervical Vestibular Evoked Myogenic Potential, Ocular Vestibular Evoked Myogenic Potential
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Gødstrup Hospital
Cybersickness, Motion Sickness
Gaze Stabilization vs Oculomotor Exercises on Cybersickness in Computer Users
Many people who use computers for long hours experience "cybersickness" (dizziness, nausea, blurred vision) because their eyes see movement on the screen but their body feels still.
- Conditions
- Cybersickness, Motion Sickness, Vestibular Diseases
- Trial name
- GAZE-CS (NCT07616596)
- Testing
- Gaze Stabilization Exercises, Oculomotor Exercises
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- University of Faisalabad
Meniere Disease, Vertigo
Safety of APSLXR in Patients Presenting Vertigo of Vestibular Origin or Meniere's Disease
The purpose of this study is to evaluate the safety of APSLXR in participants with Meniere's disease or other Verigo of vestibular origin. Pharmacokinetics will also be evaluated in a small group.
- Conditions
- Meniere Disease, Vertigo, Vertigo Vestibular
- Trial name
- NCT04674735
- Testing
- APSLXR
- Sponsor
- Apsen Farmaceutica S.A.
Vestibular Disorder, Vestibular Schwannoma
StableEyes With Active Neurofeedback
The investigators have developed a self-administered rehabilitation tool that incrementally guides the user to increase head motion to mitigate motion sickness and enhance postural recovery following centrifugation or unilateral…
- Conditions
- Vestibular Disorder, Vestibular Schwannoma, Space Motion Sickness, Motion Sickness
- Trial name
- SWAN (NCT05622344)
- Testing
- Traditional Therapy, SWAN
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Vertigo, Vestibular Diseases
China Dizziness and Vertigo Cohort Study （VERIDICAL STUDY）
The goal of this observational study is to characterize the clinical features, etiological distribution, and longitudinal outcomes of patients with dizziness and/or vertigo in real-world neurological and otolaryngological…
- Trial name
- dizziness (NCT07778901)
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Meniere's Disease, Benign Paroxysmal Positional Vertigo
CAVA: Dizziness Trial
Clinical investigation of a medical device (CAVA) for recording eye movements. Patients suffering from diagnosed dizziness conditions will wear the device for 23 hours a day, for 30 days.
- Conditions
- Meniere's Disease, Benign Paroxysmal Positional Vertigo, Recurrent Vestibulopathy, Vestibular Migraine
- Trial name
- CAVA (NCT04026516)
- Testing
- CAVA Device
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Headache Disorders, Dizziness
Headache Ear Auditory Dizziness Sinus (HEADS) Registry
The Headache, Ear, Auditory, Dizziness, Sinus (HEADS) Registry is a study over time of individuals living in the United States who experience sinus, vestibular, auditory, and headache symptoms.
- Conditions
- Headache Disorders, Dizziness, Vestibular Diseases, Sinus Disease
- Trial name
- HEADS (NCT07754266)
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Association of Migraine Disorders
Vertigo, Vestibular Disorder
Evaluation of Nystagmus Examination Using Wearable AR Glasses in Vertigo Patients
Background and Purpose: Vertigo is common in emergency and outpatient settings, yet standard oculomotor testing usually requires dedicated equipment and exam rooms.
- Conditions
- Vertigo, Vestibular Disorder, Nystagmus
- Trial name
- NCT07238387
- Testing
- Wearable Augmented Reality Glasses for Nystagmus Examination, Conventional Nystagmus Examination
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chang Gung Memorial Hospital
Vestibular Disorder, Vestibular Schwannoma
Measuring Vestibular Organ Function With Weak Alternating Current Stimulation
The goal of this clinical trial is to preliminarily evaluate the use of electrical stimulation in diagnosing disorders with the vestibular system.
- Conditions
- Vestibular Disorder, Vestibular Schwannoma, Vestibular Neuritis
- Trial name
- VESTI (NCT07267910)
- Testing
- Active transcranial electrical vestibular stimulation (Active EVS), Control measurement
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Aalto University
Meniere's Disease, Enlarged Vestibular Aqueduct Syndrome
Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic Targets
Background: Disorders of hearing instability (HI) are poorly characterized and ineffectively treated. HI can cause fluctuations in hearing thresholds and speech understanding.
- Conditions
- Meniere's Disease, Enlarged Vestibular Aqueduct Syndrome, Autoimmune Inner Ear Disease
- Trial name
- NCT04806282
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Vestibular Disorder, Aging
Testing Effectiveness of a Stochastic Noise Stimulator to Immediately Improve Balance and Gait
The goal of this intervention study is to determine if a new electronic stimulation device, similar to a TENS can improve balance and make walking easier in older individuals with reduced balance function.
- Trial name
- NCT06688578
- Testing
- Subperceptual Stimulus
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Ménière's Disease, Vestibular Migraine
The CAVA Multicentre Dizziness Trial
The CAVA trial is a diagnostic accuracy multicentre device trial which aims to quantify the extent to which the CAVA system can differentiate three common inner-ear causes of dizziness: Ménière's disease, vestibular migraine and…
- Conditions
- Ménière's Disease, Vestibular Migraine, Benign Paroxysmal Positional Vertigo (BPPV)
- Trial name
- CAVA 2 (NCT05984901)
- Testing
- The continuous ambulatory vestibular assessment (CAVA) system
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Vestibulocochlear Nerve Diseases, Vestibular Disorder
Vestibular Balance Therapy Intervention for Children
The goal of this within groups clinical trial is to determine the feasibility of a home-based vestibular balance therapy program for children with vestibular hypofunction.
- Conditions
- Vestibulocochlear Nerve Diseases, Vestibular Disorder, Bilateral Vestibular Loss
- Trial name
- VBT-C (NCT05741515)
- Testing
- Vestibular Balance Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Alabama at Birmingham
Vestibular Dysfunction, Vestibular Diseases
Effects of Wiifit vs Conventional Vestibular Rehabilitation on Dizziness and Balance in Patients With Unilateral Peripheral Vestibular Dysfunction
Unilateral Peripheral Vestibular Dysfunction (UPVD) causes dizziness, imbalance, vertigo, and reduced quality of life. Conventional Vestibular Rehabilitation Therapy (cVRT) is effective, while WiiFit-based virtual reality…
- Conditions
- Vestibular Dysfunction, Vestibular Diseases, Vertigo, Dizziness
- Trial name
- NCT07587554
- Testing
- Vestibular Rehabilitation Therapy, Wiifit Vestibular Training
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Foundation University Islamabad