Clinical trials: Vascular Accident, Brain
Stroke, Upper Extremity Paresis
Graded Repetitive Arm Supplementary Program Versus Task Based Training on Upper Limb Function in Stroke Patients
To determine effects of graded repetitive arm supplementary program versus Task based training on Upper limb function in stroke patients.
- Conditions
- Stroke, Upper Extremity Paresis, Motor Activity
- Trial name
- NCT06397170
- Testing
- Graded repetitive arm supplementary program, Task based training
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Ischemic Stroke, Motor Deficits
Effect of Vagus Nerve Stimulation Via the Outer Ear on Motor and Cognitive Deficits After Ischemic Stroke
The goal of this clinical trial is to learn if transcutaneous auricular vagus nerve stimulation (taVNS) works to treat motor and neurocognitive deficits after ischemic stroke when applied within 30 days after onset of stroke.
- Conditions
- Ischemic Stroke, Motor Deficits, Cognitive Impairment, Vagus Nerve Stimulation
- Trial name
- EVAMOS (NCT06822140)
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- Switzerland
- Volunteers
- 144 people
- Sponsor
- Rheinburg-Klinik
Hemianopsia
Therapeutic Effects of Transcranial Alternative Current Stimulation (tACS) in Chronic Post Stroke Hemianopia
Background: The most common visual field deficit after retro-chiasmatic lesions is homonymous hemianopia (HH), defined as the impossibility of seeing the contralesional visual hemisphere without ocular injury.
- Trial name
- HEMIANOTACS (NCT04043689)
- Testing
- tACS (transcranial Alternate Current Stimulation)
- Where
- France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Cerebral Ischemia
Safety and Efficacy of Sequential Therapy With Mexidol® in Patients With Chronic Cerebral Ischemia
The purpose of this study is to evaluate safety and efficacy of sequential treatment with Mexidol® in patients with chronic cerebral ischemia (CCI).
- Trial name
- MEMO (NCT06834490)
- Testing
- Mexidol
- Where
- 14 sites in Russia, Uzbekistan
- Volunteers
- 318 people
- Sponsor
- Pharmasoft
Stroke
Sleep and Motor Learning in Stroke
This study will explore whether sleep disruption in the sub-acute phase of stroke explains variation in clinical motor outcomes, and whether this relationship is mediated by variation in behavioural measures of overnight…
- Trial name
- SMiLES (NCT05746260)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Oxford
Deglutition Disorders, Stroke
Effect Of Vitalstim In Patients With Chronic Post-stroke Oropharyngeal Dysphagia
Prospective, randomized, controlled, three-arm, open-label, blinded analysis. Patients admitted with stroke diagnosis and with suspected dysphagia that meet the initial inclusion and exclusion criteria will be consented into the…
- Trial name
- VITAL (NCT02379182)
- Testing
- standard clinical care, transcutaneous electrical stimulation at sensory level, transcutaneous electrical stimulation at motor level
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Pere Clave
Ischemic Stroke, Upper Extremity Problem
VNS-REHAB At-Home - Post-Market Study for Using the Vivistim System® at Home
This is a single-arm post-market study of up to 150 participants, using up to 50 mobile therapists to conduct up to 36-hours at-home therapy.
- Trial name
- AT-HOME (NCT05691023)
- Testing
- Vivistim System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- MicroTransponder Inc.
Acute Ischemic Stroke
Xingnaojing for Moderate-to-severe Acute Ischemic Stroke (XMAS)
The main purpose of this trial is to determine whether Xingnaojing, intravenously administered within 24 hours of symptom onset, improves the 3-month outcome in participants with acute ischemic stroke.
- Trial name
- XMAS (NCT02728180)
- Testing
- Xingnaojing injection, Standard care
- Where
- China
- Volunteers
- 720 people
- Sponsor
- Dongzhimen Hospital, Beijing
Stroke, Hemiparesis
The Comparison of Virtual and Real Boxing Training in Hemiparetic Stroke Patients
The aim of this study is to compare the effects of virtual and real boxing training in addition to neurodevelopmental training on cognitive status, upper extremity functions, balance and activities of daily living in hemiparetic…
- Trial name
- NCT03651479
- Testing
- real boxing training, virtual boxing training
- Where
- Cyprus
- Volunteers
- 40 people
- Sponsor
- Eastern Mediterranean University
Atherosclerosis, Ischemia
Trial to Assess the Ocular Safety of Vorapaxar (SCH 530348) in Participants With Atherosclerosis (Study P05183)
This study is designed to evaluate the long-term ocular safety of SCH 530348 (vorapaxar) in participants with established atherosclerotic disease who are enrolled into the TRA 2°P - TIMI 50 Study (P04737) (NCT00526474).
- Conditions
- Atherosclerosis, Ischemia, Myocardial Infarction, Cerebrovascular Accident
- Trial name
- NCT00617123
- Testing
- Vorapaxar 2.5 mg
- Volunteers
- 258 people
- Sponsor
- Merck Sharp & Dohme LLC
Cardiovascular Diseases, Coronary Disease
Coronary Artery Calcium, Exercise Tests, and CHD Outcome
To investigate coronary artery calcium (CAC), detected by electron beam computed tomography (EBCT), as a predictor of coronary heart disease (CHD) mortality and morbidity, stroke, and all-cause mortality in a historical cohort…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Cerebrovascular Disorders, Heart Diseases
- Trial name
- NCT00005562
- Sponsor
- The Cooper Institute
Ischemic Stroke, Obstructive Sleep Apnea
The Recovery in Stroke Using PAP Study
The proposed study is a randomized controlled trial among an anicipated 180 participants with acute ischemic stroke and mod/severe OSA diagnosed by ambulatory polysomnography (PSG) comparing PAP treatment with usual care…
- Trial name
- RISE-UP (NCT04130503)
- Testing
- PAP, HLE
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Yale University
Aphasia
The Effect of Dual-target tACS Combined With Speech Training on Repetition Disorder After Stroke
This clinical trial aims to study whether dual-target transcranial alternating current stimulation (tACS) applied to the auditory and motor brain region can improve repetition disorder in people with stroke, and to evaluate the…
- Trial name
- NCT07347327
- Testing
- speech training, real tACS
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Ke Dong, MD
Stroke, Cerebral Infarction
Assessment of Patient Reported Health Status Questions Via Four Different Methods of Administration, in Stroke Survivors.
A Patient Reported Outcome Measure (PROM) is a questionnaire that asks patients for their views on their own health or the impact of healthcare they have received on their health and quality of life (RCN, 2011).
- Conditions
- Stroke, Cerebral Infarction, Cerebral Hemorrhage, Stroke Hemorrhagic
- Trial name
- NCT03177161
- Testing
- 15 Patient Reported Health Status Questions
- Where
- 4 sites in United Kingdom
- Volunteers
- 472 people
- Sponsor
- Dr Jonathan Hewitt
Cerebrovascular Accident
Investigation of Changes in Lower Limb Muscles After Cerebrovascular Accident
The aim of this study is to investigate lower limb muscles after cerebrovascular accident
- Trial name
- NCT04607486
- Testing
- 3DfUS and IPSA of leg muscles
- Where
- Belgium
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stroke, Gait Disorders, Neurologic
Most Effective Stimulation Site in Transcranial Direct Current Stimulation for Gait Recovery After Stoke
The aim of this study is to investigate the most effective stimulation site in transcranial direct current stimulation for gait recovery after stroke.
- Trial name
- NCT03460886
- Testing
- Ipsilesional stimulation, Contralesional stimulation, Walking on treadmill
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Samsung Medical Center
Acute Ischemic Stroke
Endovascular Stroke Treatment Only (ESTO) Trial
The specific aims of this study are to: 1. Determine whether the endovascular treatment (mechanical thrombectomy) alone without using intravenous (IV) recombinant tissue plasminogen activator (rt-PA) in acute ischemic stroke…
- Trial name
- NCT04240470
- Testing
- Thrombectomy
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Missouri-Columbia
Stroke, Ischemic
Safety and Efficacy of Therapeutic Hypothermia in Acute Ischemic Stroke
Therapeutic hypothermia (TH) in stroke has demonstrated robust neuroprotection in animals especially after ischemia-reperfusion injury, but its safety and efficacy remain controversial.
- Trial name
- THIS (NCT05779176)
- Testing
- Therapeutic hypothermia
- Where
- China
- Volunteers
- 252 people
- Sponsor
- RenJi Hospital
Stroke, Upper Extremity Paresis
The Efficacy of Upper Limb Rehabilitation With Exoskeleton in Patients With Subacute Stroke.
Loss of arm function is a common and distressing consequence of stroke. Neurotechnology-aided rehabilitation could be a promising approach to accelerate the recovery of upper limb functional impairments.
- Trial name
- PowerUPS-REHAB (NCT04697368)
- Testing
- Exoskeleton-Assisted Upper Limb Rehabilitation, Traditional Upper Limb Rehabilitation
- Where
- 7 sites in Italy
- Volunteers
- 94 people
- Sponsor
- IRCCS San Raffaele Roma
Aphasia, Stroke
Improvement of Language Disturbances After Stroke by Intensive Training and Electrical Brain Stimulation
The study aims to identify if intensive language training, consisting mainly of computer-based object naming, together with electrical brain stimulation, will lead to an improvement of language functions in patients that suffer…
- Trial name
- NCT00822068
- Testing
- anodal tDCS, cathodal tDCS
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Muenster
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