Clinical trials: Vaping Behaviors
E-cigarette Use
Evaluation of the Be Vape Free Curriculum of the Tobacco Prevention Toolkit
The Stanford Tobacco Prevention Toolkit is a free online curriculum developed for use by educators and health professionals in providing tobacco-specific prevention education to middle and high school students.
- Trial name
- NCT05493982
- Testing
- Stanford Vaping Prevention curriculum
- Where
- United States
- Volunteers
- 2,779 people, healthy volunteers welcome
- Sponsor
- Stanford University
Electronic Cigarette Use, E-Cig Use
Effects of e-Cigarettes on Perceptions and Behavior - Substudy 2
This project will assess the ways in which e-cigarette product diversity impacts the user experience to inform potential regulations by identifying product characteristics that may: (1) put young adults at risk for tobacco…
- Conditions
- Electronic Cigarette Use, E-Cig Use, Cigarette Smoking, Cigarette Use, Electronic
- Trial name
- NCT05958966
- Testing
- E-cigarette e-liquid self-administration
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Nicotine Vaping
Nicotine Flux, a Potentially Powerful Tool for Regulating Nicotine Delivery From Electronic Cigarettes
The investigators will examine the relationship between nicotine flux, nicotine form, and the rate and dose of nicotine delivery.
- Trial name
- NCT05706701
- Testing
- Nicotine vaping visit 1 (free-base nicotine), Nicotine vaping visit 1 (protonated nicotine), Nicotine vaping visit 2 (free-base nicotine)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Yale University
E-cigarette Use, Vaping
Vaper to Vaper: A Multimodal Mobile Peer Driven Intervention to Support Adolescents in Quitting Vaping
The dramatic increase in the use of e-cigarettes among U.S. adolescents has been called a national epidemic, with more adolescents now using e-cigarettes than traditional cigarettes.
- Trial name
- V2V (NCT05140915)
- Testing
- Peer Messaging, Peer Coaching via Text, Gamification
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Smoking Cessation
The Effects of Combination Zonisamide and Bupropion on Switching to an Electronic Cigarette
This three-group randomized double-blind placebo-controlled trial (N=180) will evaluate the impact of combination zonisamide and bupropion on the process of switching from combustible cigarettes (CCs) to an e-cigarette.
- Trial name
- NCT05205811
- Testing
- Bupropion, Zonisamide, E-cigarette
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Nicotine Dependence, Other Tobacco Product
Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1
This study is to examine if inhaled doses of menthol that produce low and high cooling effects change the appeal of e-cigarettes containing low and high doses of nicotine in adolescent smokers.
- Trial name
- NCT02179034
- Testing
- Nicotine, Low Dose Menthol, High Dose Menthol
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Yale University
Tobacco Use
Digital Media for Cancer Control (to Prevent Vaping and Smoking Behavior)
There is little published data on exposure to and evaluations of large-scale, online tobacco control campaigns. This project addresses the gap.
- Trial name
- DMCC (NCT04867668)
- Testing
- Anti-vaping and anti-smoking digital advertising
- Where
- United States
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- George Washington University
Nicotine Addiction, Cigarette Smoking
Abuse Liability of Reduced Nicotine Content Cigarettes in the Context of Concurrent E-Cigarette Use
Three hundred-twenty (320) adult smokers of menthol or non-menthol combustible cigarettes will be recruited and randomly assigned to one of five groups (n=64/group), who will be asked to switch for 12 weeks to ad libitum use of…
- Trial name
- DUAL (NCT02870218)
- Testing
- Smoking research cigarettes with e-cigarette, Nicotine discrimination thresholds
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Survey, E-Cig Use
Assessment of Smoking, Vaping, and Alcohol Consumption Behavior
To assess smoking, vaping, and alcohol consumption behaviors via online surveys in the population. Further, the objective is to administer additional surveys to assess which methods (e.g., pen-and-paper records, a smartphone app)…
- Conditions
- Survey, E-Cig Use, Smoking Behaviors, Alcohol Drinking
- Trial name
- NCT04150510
- Where
- United States
- Volunteers
- 3,245 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Secondhand Exposure to Electronic Cigarette
Bystanders' Exposure to Electronic Cigarette Aerosol in Confined Settings
Objective of this study is to investigate the bystanders' exposure to e-cigarette emissions in controlled conditions in confined settings. Design: a cross-sectional experimental study developed in two settings: a car and a room.
- Trial name
- NCT04140617
- Testing
- Exposure to aerosol of electronic cigarette
- Where
- Spain
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Institut Català d'Oncologia
Electronic Cigarette Use
Effects of E-cigarette Use on Health
Electronic nicotine delivery systems (ENDS) are used by millions of Americans, however their long-term health effects are unknown.
- Trial name
- VAPECHECK (NCT06610838)
- Testing
- Health Assessments
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Electronic Cigarette Use
Use Behavior, Nicotine Uptake, and Subjective Effects Comparison of Tobacco and Menthol e-Liquids by ENDS Consumers
This study is being conducted to evaluate the impact of within-flavor category (tobacco and menthol) differences in e-liquid flavors on product use behaviors, nicotine uptake, and subjective effects by current ENDS consumers when…
- Trial name
- NCT05134415
- Testing
- RELX ENDS Tobacco Flavor 1, RELX ENDS Tobacco Flavor 2, RELX ENDS Menthol Flavor 1
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cheerain HK Limited
Vaping
Feasibility of Treatment for Vaping Cessation
Researchers are gathering information on the feasibility of treating e-cigarette users with 12-weeks of varenicline (Chantix®) in assisting with stopping the use of e-cigarettes.
- Trial name
- VAPEscape (NCT04317300)
- Testing
- Varenicline, brief behavioral therapy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Smoking Cessation, Electronic Cigarette
Efficacy and Safety of E-cigarettes for Smoking Cessation in Middle-aged Heavy Smokers
Abstract Rationale. Electronic cigarette use is increasing at an exponential rate in Finland and internationally. The health consequences of vaporised aerosols in electronic cigarettes are largely unknown especially in a long…
- Trial name
- EFFECT (NCT03235505)
- Testing
- Nicotine, Varenicline Tartrate, Motivational Interview
- Where
- Finland
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Smoking, Cigarette, Electronic Cigarettes
Evaluating New Nicotine Standards for Cigarettes - Project 3
This study is designed to examine how the nicotine content of cigarettes and the nicotine concentration and flavors in e-liquids influence responses to and use of these products in adolescent smokers.
- Trial name
- CENIC2-P3 (NCT03194256)
- Testing
- Spectrum Research Cigarettes
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Brown University
Vaping
Responses to Message Source and Presentation Using Psychophysiology
The goal of this clinical trial is to use psychophysiological methods to test the effects of a message source (expert and peer) and message presentation types (one-sided and two-sided) to identify the optimal message type for…
- Trial name
- NCT06269003
- Testing
- Expert, one-sided, Expert, two-sided, Peer, one-sided
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Adolescent Substance Use
Guiding Good Choices for Health
This study evaluates the feasibility and effectiveness of implementing Guiding Good Choices (GGC), an anticipatory guidance curriculum for parents of early adolescents, in three large, integrated healthcare systems.
- Trial name
- GGC4H (NCT04040153)
- Testing
- Guiding Good Choices
- Where
- 3 sites in United States
- Volunteers
- 3,636 people, healthy volunteers welcome
- Sponsor
- University of Washington
Vaping, Underage
Human Factors Validation and Usability Testing of the IKE Age-Gating System
A multi-center human factors validation study to demonstrate the function of the IKE Bluetooth system on a chip (SoC) and mobile applications ability to age-gate a device, accurately identify an individuals age, race/ethnicity…
- Trial name
- NCT06952569
- Testing
- IKE System
- Where
- 4 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- IKE Tech
Adolescent Behavior, Tobacco Use
Media Literacy for High School Tobacco Prevention
This research project will explore the feasibility and acceptability of a web-based media literacy tobacco prevention program. The project will be conducted with 9th or 10th graders in two high schools in Pittsburgh, Pennsylvania.
- Conditions
- Adolescent Behavior, Tobacco Use, E-Cig Use
- Trial name
- NCT05120466
- Testing
- AD IT UP media literacy intervention, Usual health education curriculum
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Periodontal Diseases, Dysbiosis
Effect of Aerosol From THS and Cigarette Smoke on Periodontal Tissues and Its Microbiome
Cigarette smoke has an adverse effect on the entire body as well as on the supporting apparatus of the teeth. THS (tobacco heating system) are new products on the market in which tobacco is heated and not burned like in classic…
- Trial name
- NCT06480877
- Testing
- Taking a swab from periodontal pockets or gingival sulci
- Where
- Croatia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Center Rijeka