E-cigarette UseNCT05493982
Evaluation of the Be Vape Free Curriculum of the Tobacco Prevention Toolkit
A study testing Stanford Vaping Prevention curriculum in people with E-cigarette Use, run by Stanford University at 1 site in United States.
Trial summary
The Stanford Tobacco Prevention Toolkit is a free online curriculum developed for use by educators and health professionals in providing tobacco-specific prevention education to middle and high school students. Read more about this study
- Who is it for?
- Ages 10 to 20 yearsHealthy volunteers can take part
- Conditions the study is for
- E-cigarette Use
- What is being tested?
- Stanford Vaping Prevention curriculum
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 2,779 participants
- Where
- 1 siteUnited States
- Study dates
- 19 Oct 2022to 8 May 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 10 to 20 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Middle school and high school students receiving health education at schools participating in the study
Who cannot join
- None
Trial locations and contacts
1 site in 1 country.
About this study
The Stanford Tobacco Prevention Toolkit is a free online curriculum developed for use by educators and health professionals in providing tobacco-specific prevention education to middle and high school students. A set of lessons focused on e-cigarette/vaping prevention education specifically is called the Be Vape Free curriculum. The aims of this study are to determine: (1) whether the Be Vape Free curriculum is effective in increasing middle and high school students' resistance to using tobacco and in decreasing positive attitudes towards and intentions to use e-cigarettes; (2) whether the Curriculum is effective in changing middle and high school students' actual use of tobacco; and (3) Examine heterogenous treatment effects identifying groups that benefit the most and those who do not benefit at all from the intervention.
- Conditions
- E-cigarette Use
- Being tested
- Stanford Vaping Prevention curriculum
- Keywords
- youth, tobacco, education, health, prevention, vaping, e-cigarette
- Medical subject headings
- Vaping
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Stanford Vaping Prevention curriculumBehavioural
Stanford vaping prevention curriculum delivered as a 5-session course administered in a school classroom setting.
| Study group | Role | What they receive |
|---|---|---|
| Receives Stanford vaping prevention curriculum (pilot phase) | Experimental | Stanford vaping prevention curriculum is administered as pilot arm preceding main experimental intervention. Receives: Behavioral: Stanford Vaping Prevention curriculum |
| Receives Stanford vaping prevention curriculum (randomized phase) | Experimental | Stanford vaping prevention curriculum is administered. Receives: Behavioral: Stanford Vaping Prevention curriculum |
| Does not receive Stanford vaping prevention curriculum (randomized phase) | No intervention | Receives another curriculum or no vaping prevention education. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in e-cigarette use
Investigator-originated survey measures (questions) assess ever e-cigarette use \& past 30-day tobacco use. This outcome measure assesses e-cigarette use.
Measured: Change from baseline to follow-up at approximately 156 weeks
Change in intention to use of e-cigarettes scaled score as measured by investigator-originated survey
This survey measures change in intention to use e-cigarettes with questions related to the participant's knowledge of and resistance to use of e-cigarettes.
Measured: Change from baseline to follow-up at approximately 156 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Aug 2022
- Study start19 Oct 2022
- Primary completion8 May 2026
- Study completion8 May 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for E-cigarette UseStudies of the same condition, open and under way.
- More trials run by Stanford UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 2,779 participants (actual)
Sponsor and investigators
- Lead sponsor
- Stanford University
- Sponsor type
- University, hospital or other
- Collaborators
- National Cancer Institute (NCI)
- Responsible party
- Principal investigator, Bonnie Halpern-Felsher, Stanford University
- Investigators
- Bonnie Halpern-Felsher, Ph.D., Principal investigator, Stanford University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05493982
- Sponsor's protocol ID
- 61965
- Other IDs
- 1R01CA263121
- Status last verified
- May 2026
- First submitted
- 6 Aug 2022
- Last updated
- 27 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 27 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of the Be Vape Free Curriculum of the Tobacco Prevention Toolkit
- ClinicalTrials.gov ID
- NCT05493982
- Acronym / sponsor ID
- 61965
- Conditions
- E-cigarette Use
- Keywords
- youth, tobacco, education, health, prevention, vaping, e-cigarette
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 2,779 participants (actual)
- Lead sponsor
- Stanford UniversityUniversity, hospital or other
- Collaborators
- National Cancer Institute (NCI)
- Study start
- 19 Oct 2022 (actual)
- Primary completion
- 8 May 2026 (actual)
- Study completion
- 8 May 2026 (actual)
- First posted
- 9 Aug 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The Stanford Tobacco Prevention Toolkit is a free online curriculum developed for use by educators and health professionals in providing tobacco-specific prevention education to middle and high school students. A set of lessons focused on e-cigarette/vaping prevention education specifically is called the Be Vape Free curriculum. The aims of this study are to determine: (1) whether the Be Vape Free curriculum is effective in increasing middle and high school students' resistance to using tobacco and in decreasing positive attitudes towards and intentions to use e-cigarettes; (2) whether the Curriculum is effective in changing middle and high school students' actual use of tobacco; and (3) Examine heterogenous treatment effects identifying groups that benefit the most and those who do not benefit at all from the intervention.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Receives Stanford vaping prevention curriculum (pilot phase) | Experimental | Behavioral: Stanford Vaping Prevention curriculumStanford vaping prevention curriculum is administered as pilot arm preceding main experimental intervention. |
| Receives Stanford vaping prevention curriculum (randomized phase) | Experimental | Behavioral: Stanford Vaping Prevention curriculumStanford vaping prevention curriculum is administered. |
| Does not receive Stanford vaping prevention curriculum (randomized phase) | No intervention | –Receives another curriculum or no vaping prevention education. |
Who may qualify
- Ages
- 10 to 20 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (1 listed)
- Middle school and high school students receiving health education at schools participating in the study
Key exclusion criteria (1 listed)
- None
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Stanford Vaping Prevention curriculumStanford vaping prevention curriculum delivered as a 5-session course administered in a school classroom setting. | Behavioural | Receives Stanford vaping prevention curriculum (pilot phase), Receives Stanford vaping prevention curriculum (randomized phase) |
Primary outcome
Change in e-cigarette use
Time frame: Change from baseline to follow-up at approximately 156 weeks
Investigator-originated survey measures (questions) assess ever e-cigarette use \& past 30-day tobacco use. This outcome measure assesses e-cigarette use.
Change in intention to use of e-cigarettes scaled score as measured by investigator-originated survey
Time frame: Change from baseline to follow-up at approximately 156 weeks
This survey measures change in intention to use e-cigarettes with questions related to the participant's knowledge of and resistance to use of e-cigarettes.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 May 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Bonnie Halpern-Felsher, Ph.D. principal investigator
Stanford University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Stanford Vaping Prevention curriculum in people with E-cigarette Use, run by Stanford University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 27 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in e-cigarette use (time frame: Change from baseline to follow-up at approximately 156 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 May 2026.