Clinical trials: Validation Studies
Ocular Pain, OSDI
Validation of Ocular Pain Questionnaire: Single-center, Prospective Observational Study
This study will be a single-center, observational, prospective validation study with survey and sample characteristics comparable to similar validation studies in the literature.
- Conditions
- Ocular Pain, OSDI, OPAS
- Trial name
- NCT06656260
- Volunteers
- 333 people
- Sponsor
- IRCCS Ospedale San Raffaele
Kidney Transplantation
Model-based Medication Dosing Assist for Tacrolimus in Kidney Transplantation
The daily dosing of tacrolimus, the most important immunosuppressant used after kidney transplantation, is a rather complex process in which many factors can have an influence in each individual in a unique way and variable over…
- Trial name
- MIPDTac (NCT07030660)
- Testing
- Model-Informed Precision Dosing (MIPD)
- Where
- Belgium
- Volunteers
- 357 people
- Sponsor
- KU Leuven
Healthy Male Adults Participants, Vasectomy
Plan A Novel Delivery Device Study
This study will evaluate the safety and usability of the Delivery Lumen Access Device (DLAD) in accessing the vas deferens in up to 30 healthy males. This is a prospective, non-randomized, open label interventional study.
- Trial name
- NCT06891729
- Testing
- Delivery Lumen Access Device, DLAD
- Where
- 2 sites in Australia, Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Next Life Sciences
Pulse Oximetry, Oxygen Measurements, SpO2
SpO2 Validation Study-Philips Optimus
Validation study to validate the SpO2 accuracy performance of the Sponsor's SpO2 sensors over the range of 70-100% SaO2 during non-motion conditions assessed by CO-Oximetry
- Trial name
- NCT07215429
- Testing
- No intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Stomach Neoplasms, Aged
Model for Prognosis of Elderly Gastric Cancer Patients
This study aims to develop and validate a Random Survival Forest (RSF) model for predicting long-term survival in elderly patients following curative resection for gastric cancer.
- Trial name
- NCT06393153
- Where
- China
- Volunteers
- 1,202 people
- Sponsor
- Chang-Ming Huang, Prof.
Colorectal Cancer Liver Metastasis
Prospective Validation of an AI Model for Predicting Liver Metastasis in Colorectal Cancer
This is a prospective, multicenter, observational study designed to validate the predictive accuracy of a pre-developed multimodal deep learning model.
- Trial name
- NCT07392567
- Testing
- Multimodal Deep Learning Prediction Model
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Tongji Hospital
GERD, Acid Reflux Disease
Validation of Patient-reported Outcomes Measures for the Assessment of Gastroesophageal Reflux Disease (GERD) Symptoms
This research study is being done to gather information about how to do further clinical studies using AZD3355 as an add-on treatment to proton pump inhibitors (PPI).
- Conditions
- GERD, Acid Reflux Disease, Heartburn, Regurgitation
- Trial name
- C27 (NCT00703534)
- Testing
- AZD3355, Gelusil®
- Where
- 84 sites in United States
- Volunteers
- 478 people
- Sponsor
- AstraZeneca
Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD)
Validation of the CIDI 5.0 Against the SCID-5 for Lifetime Mental Disorders
The World Health Organization Composite International Diagnostic Interview (CIDI) is a fully structured diagnostic tool designed for lay interviewers to assess the prevalence of mental and substance use disorders.
- Conditions
- Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Posttraumatic Stress Disorder (PTSD)
- Trial name
- NCT07604753
- Testing
- CIDI-5
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Scoliosis
Study of 3D Scanning for Adolescent Scoliosis
The investigators aim to validate three-dimensional topographical scanning technology as a tool for evaluation of scoliosis. Through the incorporation of 3D topographical technology in the measurement of deformity, the…
- Trial name
- NCT06035952
- Testing
- 3D topographical scan
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- NSite Medical
Shoulder Surgery
Turkish Validity and Reliability Study of Hospital for Special Surgery Shoulder Surgery Expectations Survey
This study aims to evaluate the Turkish validity and reliability of the Hospital for Special Surgery Shoulder Surgery Expectations Survey.
- Trial name
- NCT06553092
- Testing
- Turkish Version of the Hospital for Special Surgery Shoulder Surgery Expectations Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gazi University
Metastatic Malignant Neoplasm in the Prostate Gland, Prostate Carcinoma
Prospective Exploratory Study of FAPi PET/CT in Prostate Cancer With Histopathology Validation
This exploratory study investigates how a new imaging technique called FAPI PET/CT can determine where and to which degree the FAPI tracer (68Ga-FAPi-46) accumulates in normal and cancer tissues in patients with prostate cancer.
- Conditions
- Metastatic Malignant Neoplasm in the Prostate Gland, Prostate Carcinoma, Recurrent Prostate Carcinoma
- Trial name
- FAPI PET Prost (NCT04457232)
- Testing
- Computed Tomography, Gallium Ga 68 FAPi-46, Positron Emission Tomography
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Potassium Measurement
GAMMA Study: Patient Self-testing of Capillary Blood Potassium: A Validation Study and Measurement Performance in Patients.
Multicentre, open, prospective and interventional study investigating the CardioRenal device in capillary blood of patients.It will be conducted at multiple investigational sites.
- Trial name
- NCT05975632
- Testing
- Device: Self testing Potassium device
- Where
- 6 sites in France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- CardioRenal
Cancer, Breast, Triple Negative Breast Cancer
VISION: Triple Negative Breast Cancer Sample and Clinical Data Acquisition Study
Background: Despite improvements in the treatment of Triple Negative Breast Cancer (TNBC), the cancer returns in half of the women and shockingly 40% are dead within 5 years of their initial cancer diagnosis.
- Conditions
- Cancer, Breast, Triple Negative Breast Cancer, Early-stage Breast Cancer
- Trial name
- NCT06409221
- Testing
- Non-interventional study, Observational only
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Concr
Cardiovascular Diseases, Blood Pressure
VicorderCS NIBP Validation Study to Review The Ability to Capture Blood Pressure Measurements
80 Beats Medical introduces the VicorderCS, the next generation of our Vicorder technology designed to manage hypertension and cardiovascular risks.
- Conditions
- Cardiovascular Diseases, Blood Pressure, Hypertension
- Trial name
- NCT06560034
- Testing
- VicorderCS
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- 80 Beats Medical
Myofascial Pain Syndrome (MPS)
High-Intensity Laser Therapy for Trapezius Myofascial Pain (HILT-TRAP Study)
This study aims to evaluate the effectiveness of optimized High-Intensity Laser Therapy (HILT) compared with sham treatment in patients with trapezius myofascial pain syndrome.
- Trial name
- HILT-TRAP Stud (NCT07352787)
- Testing
- High-Intensity Laser Therapy
- Where
- Iraq
- Volunteers
- 104 people
- Sponsor
- Neveen Abd El Maksoad Kohaf
Shoulder Pain
The Chinese Version of the American Shoulder and Elbow Surgeons Standardized Shoulder Assessment Form Questionnaire, Patient Self-report Section: A Cross-cultural Adaptation and Validation Study
Background: The patient self-report section of the American Shoulder and Elbow Surgeons Standardized Shoulder Assessment Form (ASESp) is one of the most validated and reliable assessment tools.
- Trial name
- NCT04755049
- Testing
- The Chinese version of the American Shoulder and Elbow Surgeons standardized shoulder assessment form questionnaire
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Cheng-Kung University Hospital
Healthy Female Volunteers
Validation Study in Healthy Female Volunteers: A Comparison of Two Neurotech Vital Devices Set up to Provide Different Types of Electrical Stimulation
This research is being carried out in order to compare two alternative versions of the Neurotech Vital Devices which have been set up to provide two different types of stimulation.
- Trial name
- NCT01632748
- Testing
- Neurotech Vital Device, Modified Neurotech Vital Device
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bio-Medical Research, Ltd.
Oxygen Saturation Measurement
Controlled Desaturation Study for Perin Health Patch Validation
This study aims to test the accuracy of the Perin Health Patch (PHP), a non-invasive, chest-worn device that measures blood oxygen levels, by comparing its readings to a standard pulse oximeter device.
- Trial name
- NCT06680700
- Testing
- Perin Health Patch
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Perin Health Devices
Ovarian Neoplasms, Ovarian Cancer
Prospective Sample Collection Study for a Blood-Based cfDNA Methylation Assay for Ovarian Cancer Detection
The goal of this observational study is to learn whether a blood-based cell-free DNA (cfDNA) methylation assay can help detect ovarian cancer, especially early-stage ovarian cancer, in women undergoing clinical evaluation for…
- Conditions
- Ovarian Neoplasms, Ovarian Cancer, Early Detection of Cancer
- Trial name
- NCT07593833
- Testing
- Blood-Based cfDNA Methylation Assay for Ovarian Cancer Detection
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Tongji Hospital
Coronary Artery Disease, Plaque, Atherosclerotic
Identifying Vulnerable CoronAry PLaqUes With Artificial IntElligence-assisted CT Angiography
The goal of this observational study is to develop an automatic whole-process AI model to detect, quantify, and characterize plaques using coronary CT angiography in coronary artery disease patients.
- Trial name
- VALUE (NCT06025305)
- Testing
- Intravascular imaging test, Coronary plaque assessment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Jinling Hospital, China