Clinical trials: Vaginal Prolapse
Pelvic Organ Prolapse, Female Urogenital Diseases
Pelvic Organs Prolapse Treatment Using Neodymium Laser
The aim of this prospective study is investigation of efficiency and safety of medical device "Magic Max" ("Magic Gyno" from August 2024) for preoperative treatment of pelvic organs prolapse I-II degree of severity.
- Trial name
- NCT05000957
- Testing
- Laser Treatment, Blood analysis, Сlinical urine test
- Where
- Russia
- Volunteers
- 129 people
- Sponsor
- MeLSyTech, Ltd
Anaemia Postoperative
Clinical Utility of Postoperative Hemoglobin Testing
The purpose of this study is to evaluate how many patients have hemoglobin less than 10 g/dL at post-operative day 1
- Trial name
- NCT04170764
- Where
- United States
- Volunteers
- 664 people
- Sponsor
- TriHealth Inc.
Pelvic Organ Prolapse
Clinical Investigation to Evaluate Safety and Performance of the EndoFast Reliant™ System in Vaginal Wall Reinforcement
The purpose of this study is to clinically assess the safety and performance of the EndoFast Reliant™ system as a less invasive treatment for Pelvic Organ Prolapse.
- Trial name
- NCT00446693
- Testing
- EndoFast Reliant™ system for Pelvic Organ Prolapse repair
- Where
- 3 sites in France, Israel
- Volunteers
- 20 people
- Sponsor
- Endogun Medical Systems Ltd.
Pelvic Organ Prolapse
Inflammation and Cellular Immunity in Vaginal Tissue in Patients With Pelvic Organ Prolapse
The aim of this study is to investigate the inflammatory and maturation processes of immature myeloid cells (IMC) in the vaginal tissue in women with advanced pelvic organ prolapse (POP) (stage III-IV) and in normal non-POP…
- Trial name
- NCT03748693
- Testing
- Hysterectomy, Colporrhaphy
- Volunteers
- 20 people
- Sponsor
- Hillel Yaffe Medical Center
Vaginal Prolapse
Anterior Vaginal Wall Reconstruction
The purpose of this study is to assess the effectiveness of the polypropylene tape in preventing cystocele recurrence when placed underneath the bladder base as a concomitant measure to the anterior colporrhaphy procedure.
- Trial name
- NCT00571350
- Testing
- tvt-o operation, tvt o operation
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Hippocration General Hospital
Constipation, Prolapse, Vaginal
Effect of Preoperative Fiber on Postoperative Bowel Function
Post-operative constipation is one of the most common complaints after pelvic organ prolapse surgery. Psyillum fiber is an FDA-approved, over the counter dietary supplement that is commonly used to treat constipation.
- Trial name
- NCT04882995
- Testing
- Psyillium fiber
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Pelvic Organ Prolapse
Comparisons of Clinical Outcomes Between Novel Tailored Transvaginal Mesh Surgery and Vaginal Native Tissue Repair Surgery for Pelvic Organ Prolapse
The issue of whether utilizing the mesh in the surgical treatment of pelvic organ prolapse remained undetermined.Thus, the aim of this study is to analyze clinical outcome of women who underwent pelvic organ prolapse surgeries…
- Trial name
- NCT02465710
- Testing
- Pelvic organ prolapse surgery without mesh, Pelvic organ prolapse surgery with mesh
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University Hospital
Pelvic Organ Prolapse
Vaginal Uphold Hysteropexy and Laparoscopic Sacral Hysteropexy for the Treatment of Uterovaginal Pelvic Organ Prolapse
The purpose of this study is to evaluate surgical success or failure one year after surgery for pelvic organ prolapse.
- Trial name
- VAULT (NCT01377142)
- Testing
- Laparoscopic sacral hysteropexy, Vaginal mesh hysteropexy
- Where
- 8 sites in United States, Canada
- Volunteers
- 148 people
- Sponsor
- The Cleveland Clinic
Urinary Incontinence, Pelvic Organ Prolapse
Evaluate Women After Vaginal Surgery for Urinary Symptoms and Sexual Function
Assess the outcomes of vaginal surgeries and its impact on sexual function and urinary symptoms.
- Conditions
- Urinary Incontinence, Pelvic Organ Prolapse, Surgery
- Trial name
- NCT00376441
- Testing
- Vaginal Surgery
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Leiomyoma, Uterine, Benign Gynecological Disease
Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES Hysterectomy
vNOTES (vaginal natural orifice transluminal endoscopic surgery) hysterectomy is performed entirely through the vagina, with no abdominal incision.
- Conditions
- Leiomyoma, Uterine, Benign Gynecological Disease, Abnormal Uterine Bleeding (AUB), Uterine Prolapse
- Trial name
- vNOTES_NMBDIET (NCT07730970)
- Testing
- Deep Neuromuscular Blockade (NMB), Standard (moderate) neuromuscular blockade, Preoperative low-residue diet
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Pelvic Organ Prolapse, Hysterectomy
Evaluation of the Relationship Between Vaginal and Lower Urinary Tract Microbiomes and Infection After Hysterectomy
The purpose of this study is to learn more about the microbes (bacteria) that live in the vagina and the bladder. The investigators are doing this research study to understand the relationship between microbes (the microbiome)…
- Conditions
- Pelvic Organ Prolapse, Hysterectomy, Urinary Tract Infection
- Trial name
- NCT02751073
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Mayo Clinic
Pelvic Organ Prolapse
Randomized,Multicentric Study to Treat Prolapse After Hysterectomy With Amreich Procedure or Total Prolift Procedure
Head to Head comparison of perioperative complications and secondary the impact of operation techniques with or without mesh on patients suffering from pelvic organ prolapse on quality of life.
- Trial name
- NCT00572702
- Testing
- Vaginal fixation Amreich-Richter, Prolift total
- Where
- 5 sites in Czechia
- Volunteers
- 200 people
- Sponsor
- Charles University, Czech Republic
Pelvic Organ Prolapse
Unilateral Versus Bilateral High Uterosacral Ligament Suspension Following vNOTES Hysterectomy for Apical Pelvic Organ Prolapse: A Prospective Study
This study aims to compare unilateral and bilateral high uterosacral ligament suspension techniques performed following vaginal hysterectomy in patients with pelvic organ prolapse.
- Trial name
- HUSLS (NCT07552337)
- Testing
- High Uterosacral Ligament Suspension
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Pelvic Organ Prolapse (POP)
Restorelle Direct Fix Anterior and Posterior (A&P) for Female Pelvic Organ Prolapse: A Prospective Post Market Study
This is a prospective, multi-center study designed to assess the palpability of the Restorelle Direct Fix A\&P mesh after vaginal reconstruction surgery.
- Trial name
- (A&P) (NCT01378065)
- Testing
- Restorelle Direct Fix A&P
- Where
- 6 sites in United States
- Volunteers
- 31 people
- Sponsor
- Coloplast A/S
Genital Prolapse
Vaginal Estriol Before and Vaginal Surgery for Prolapse
The purpose of this study is to determine whether the vaginal estriol before vaginal surgery for pelvic statics disorders is more efficacy of no estriol treatment on vaginal health and quality of life.
- Trial name
- VSaE (NCT02906111)
- Testing
- estriol, vaginal surgery
- Volunteers
- 88 people
- Sponsor
- Salvatore Caruso
Pelvic Organ Prolapse
The Development of De-novo Stress Urinary Incontinence After Stage II-III Pelvic Organ Prolapse Surgery
Surgery for Stage II-III Pelvic organ prolapse
- Trial name
- NCT03221725
- Testing
- sacrospinous ligament fixation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Prolapse, Vaginal
Transperineal Ultrasound Evaluation of Vesicourethral Angle and de Novo SUI After Colpocleisis Surgery
This prospective observational study aims to evaluate changes in the vesicourethral angle using transperineal ultrasound before and after colpocleisis surgery, and to assess the relationship of these changes with the development…
- Trial name
- colpocleisis (NCT07071818)
- Testing
- Colpocleisis Group
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Prolapse; Female, Prolapse, Vaginal
What Affects Willingness to Self-manage a Pessary?
Pessary self-management is defined as the patient's ability to remove and reinsert their pessary themselves at home. Previous research has suggested that some women may prefer being able to remove and reinsert their pessary as…
- Trial name
- NCT05750615
- Testing
- Uncertain what intervention will be co-created
- Where
- United Kingdom
- Volunteers
- 132 people
- Sponsor
- Manchester University NHS Foundation Trust
Pelvic Organ Prolapse
Single Versus Multi-port Robotic Assisted Sacrocolpopexy for Repair of Vaginal Apex Prolapse
A prospective randomized controlled study intended to compare the efficacy of 2 methods of robotic assisted sacrocolpopexy for the repair of vaginal apex prolapse: 1. Via single-port. 2. Via multi-port.
- Trial name
- NCT03034499
- Testing
- Single-port sacrocolpopexy, Multi-port sacrocolpopexy
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rambam Health Care Campus
Urinary Retention, Pelvic Organ Prolapse
Urinary Retention After Removing Urinary Catheter at 24 Hour Versus 48 Hour in Patients With Vaginal Surgery
Comparison incident of urinary retention in patients with vaginal surgery of pelvic organ prolapse, who removed urinary catheter at 24 hours versus 48 hours after surgery
- Trial name
- NCT04954443
- Testing
- Removing urinary catheter
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand