Clinical trials: Uveitic Macular Edema
Uveitis, Macular Edema
Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial
The Macular Edema Ranibizumab v. Intravitreal anti-inflammatory Therapy (MERIT) Trial will compare the relative efficacy and safety of intravitreal methotrexate, intravitreal ranibizumab, and the intravitreal dexamethasone…
- Trial name
- MERIT (NCT02623426)
- Testing
- Dexamethasone intravitreal implant 0.7 mg, Intravitreal Methotrexate 400 µg, Intravitreal Ranibizumab 0.5 mg
- Where
- 33 sites in United States, Australia and 3 more
- Volunteers
- 194 people
- Sponsor
- JHSPH Center for Clinical Trials
Diabetic Macular Edema, Uveitic Macular Edema
A Study to Investigate RO7200220 as Monotherapy and in Combination With Ranibizumab in Participants With Diabetic and Uveitic Macular Edema
The purpose of this study was to assess the safety and tolerability of RO7200220 as monotherapy (diabetic macular edema [DME] or uveitic macular edema [UME] population) and in combination with ranibizumab (DME population only).
- Trial name
- DOVETAIL (NCT06771271)
- Testing
- RO7200220, Ranibizumab
- Where
- 19 sites in United States
- Volunteers
- 85 people
- Sponsor
- Hoffmann-La Roche
Uveitic Macular Edema
Vamikibart in Participants With Uveitic Macular Edema
This study will assess the efficacy and safety of vamikibart in participants with uveitic macular edema.
- Trial name
- Sandcat (NCT05642325)
- Testing
- Vamikibart
- Where
- 94 sites in United States, Argentina and 17 more
- Volunteers
- 256 people
- Sponsor
- Hoffmann-La Roche
Uveitis Related Cystoid Macular Edema, Cystoid Macular Edema, Postoperative
Multicenter Study on the Efficacy and Safety of OCS-01 in Subjects With Uveitis Related and Post Surgical Macular Edema
The goal of the LEOPARD clinical trial is to investigate a new kind of steroid eye drops, OCS-01. Macular edema is a condition in which there is collection of fluid (edema) in the back of the eye (Macula) and it can lead to…
- Trial name
- LEOPARD (NCT05608837)
- Testing
- OCS-01
- Where
- 8 sites in United States
- Volunteers
- 28 people
- Sponsor
- Quan Dong Nguyen
Macular Edema, Uveitis
TAHOE: Intravitreal Dexamethasone Implant (Ozurdex) for Uveitic Macular Edema
The purpose of this study is to determine whether an intravitreal dexamethasone implant (Ozurdex, Allergan) is effective to manage macular edema secondary to non-infectious uveitis.
- Trial name
- NCT01870440
- Testing
- Ozurdex Intravitreal Injection (0.7 mg)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Northern California Retina Vitreous Associates
Uveitic Cystoid Macular Edema
Pilot Study of Ranibizumab (Lucentis) for Uveitic Cystoid Macular Edema
Uveitic Cystoid Macular Edema (CME) is a major cause of visual loss associated with uveitis. Systemic and/or local corticosteroid therapy and systemic immunosuppression with steroid-sparing agents such as cyclosporine…
- Trial name
- NCT00826618
- Testing
- ranibizumab
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Miami
Uveitis
Microplasmin Intravitreal Administration in Participants With Uveitic Macular Edema
The objective of this study is to investigate the safety and efficacy of microplasmin as a treatment for uveitic macular edema.
- Trial name
- MIME (NCT01194674)
- Testing
- Microplasmin
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Macular Edema, Uveitis
PeriOcular and INTravitreal Corticosteroids for Uveitic Macular Edema Trial
To evaluate the relative efficacy of three commonly utilized regional corticosteroids for the regional treatment of uveitic macular edema: periocular triamcinolone acetonide; intravitreal triamcinolone acetonide; intravitreal…
- Trial name
- POINT (NCT02374060)
- Testing
- Periocular triamcinolone 40 mg, Intravitreal triamcinolone 4 mg, Dexamethasone intravitreal implant
- Where
- 26 sites in United States, Australia and 2 more
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- JHSPH Center for Clinical Trials
Uveitic Macular Edema, Intraocular Inflammation
Pilot Study for the Evaluation of Intravitreal Infliximab in the Treatment of Uveitic Macular Edema
The purpose of this study is to determine if intravitreal infliximab is a safe and effective treatment for macular edema secondary to uveitis.
- Trial name
- NCT00958906
- Testing
- Infliximab (intravitreal, 2.0mg/0.05ml)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Uveitis, Cystoid Macular Edema
Posterior Subtenon Versus Intravitreal Injection of Triamcinolone Acetonide for Treatment of Uveitic Cystoid Macular Edema
Macular edema is the most common sight threatening complication of uveitis which can lead to permanent loss of central vision. Triamcinolone acetonide ( the study drug)injection for treatment of cystoid macular edema(CME) is well…
- Trial name
- NCT02598869
- Testing
- Triamcinolone Acetonide
- Sponsor
- Oregon Health and Science University
Inflammatory Macular Edema
Efficacy and Tolerance Comparison Between Subconjunctival Injection of Triamcinolone and Intravitreal Implant of Dexamethasone for the Treatment of Inflammatory Macular Edema
Corticosteroids, whether injected peri- or intra-ocularly, remain indispensable tools of the therapeutic arsenal in treating inflammatory macular edema.
- Trial name
- TRIOZ (NCT02556424)
- Testing
- Dexamethasone, Triamcinolone
- Where
- 16 sites in France
- Volunteers
- 114 people
- Sponsor
- Nantes University Hospital
Uveitis
The Treatment of Uveitic Cystoid Macular Edema With Topical Interferon Gamma
Background: Uveitis is a serious inflammatory condition that affects the eye and can cause vision loss. A common secondary problem associated with uveitis is macular edema (swelling).
- Trial name
- NCT00943982
- Testing
- Interferon Gamma 1-b
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Eye Institute (NEI)
Uveitis, Cystoid Macular Edema
The Comparison Between the Therapeutic Affect of Intravitreal Diclophenac and Triamcinolone in Persistent Uveitic Cystoids Macular Edema
Cystoids macular edema (CME) is one of the most common causes of low vision due to uveitis. The treatment for reducing the intra-ocular inflammation can decrease the macular edema.
- Trial name
- NCT00893854
- Testing
- Diclophenac, Triamcinolone
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
Time Efficiency Comparison of Two IntraVitreal Injection Techniques
Prospective, single-center, randomized, clinical trial (RCT) comparing the time efficiency and safety of a single-use intravitreal injection (IVI) guide versus a traditional technique using a dual blade speculum among patients…
- Conditions
- Neovascular Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion With Macular Edema, Uveitic Macular Edema
- Trial name
- TIVI (NCT04455399)
- Testing
- Intravitreal injection guide (Malosa), Dual Blade Eyelid Speculum
- Where
- Philippines
- Volunteers
- 200 people
- Sponsor
- Peregrine Eye and Laser Institute
Macular Edema
Evaluation of Macular Edema After AcF Implant's Injection, 1 Month After the Last DXM Implant
Patients with diabetic macular edema (DME) or uveitis-related macular edema who have failed first-line therapy such as anti-VEGF, laser treatments, or dexamethasone implants (DXM) are candidates for treatment with an intravitreal…
- Trial name
- ILUV1MOIS2 (NCT05996822)
- Testing
- ACF injection
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Nantes University Hospital
Uveitis Related Cystoid Macular Edema, Steroid-induced Glaucoma - Borderline
The LIMO Study, Lucentis for Treatment of Uveitic Patients With Refractory Cystoid Macular Oedema
Anti-vascular endothelial growth factor (VEGF) treatments show great promise in the treatment of a variety of retinal diseases. This study addresses a condition which affects a large number of our patients in whom the…
- Trial name
- NCT01564108
- Testing
- Ranibizumab
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Macular Edema, Uveitis
Microperimetry in Macular Edema
In uveitic patients with fluorescein angiographically proven macular edema, a fundus related microperimetry is performed and results are correlated with foveal thickness as measured with optical coherence tomography (OCT).
- Trial name
- NCT00791726
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- St. Franziskus Hospital
Uveitis
Efficacy, Safety and Tolerability of Repeated Dosis of Intravitreous Bevacizumab in Uveitic Macular Oedema
The purpose of this study is to determine whether intravitreous bevacizumab or intravitreous triamcinolone acetonide are effective and safe in the treatment of uveitic macular oedema
- Trial name
- EBEV (NCT01095809)
- Testing
- bevacizumab, triamcinolone acetonide
- Where
- 5 sites in Spain
- Volunteers
- 5 people
- Sponsor
- Hospital Clinic of Barcelona
Uveitis, Macular Edema
Autofluorescence in Uveitic and Diabetic Macular Edema
The aim of this study is to determine whether fundus autofluorescence and macular pigment distribution in inflammatory and diabetic macular edema are altered.
- Trial name
- NCT00956124
- Where
- Germany
- Sponsor
- St. Franziskus Hospital
Uveitis, Macular Edema
Effects of Conbercept in Refractory Uveitic Macular Edema and VEGF
As a primary exploratory study, this study aims to evaluate the short-term effectiveness of intravitreal Conbercept injection in UME, and to explore the correlation between inflammatory factors like VEGF and the responsiveness to…
- Conditions
- Uveitis, Macular Edema, Vascular Endothelial Growth Factor, Effect of Drugs
- Trial name
- NCT04296838
- Testing
- intravitreal injection of Conbercept
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Peking Union Medical College Hospital