Clinical trials: Urology
Overactive Bladder, Urgency Urinary Symptoms
Controlling Urgency Through Relaxation Exercises
We propose to conduct a rigorous, 12-week, randomized controlled trial of two relaxation therapies in 160 ambulatory women who report an average of at least 3 urgency-associated voiding or incontinence episodes per day.
- Conditions
- Overactive Bladder, Urgency Urinary Symptoms, Urgency Incontinence
- Trial name
- CURE (NCT02202031)
- Testing
- Paced Respiration, Music Therapy
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Renal Disease, End-Stage, Renal Insufficiency, Chronic
Bosutinib In Subjects With Renal Impairment
This is a two-staged study of a single dose of 200 mg of bosutinib given to subjects with renal impairment and matching healthy volunteers.
- Conditions
- Renal Disease, End-Stage, Renal Insufficiency, Chronic, Renal Insufficiency, Acute
- Trial name
- NCT01233882
- Testing
- Bosutinib
- Where
- 5 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Pfizer
Interstitial Cystitis, Mindfulness
Mindfulness-Based Therapy for Interstitial Cystitis/Bladder Pain Syndrome
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a poorly understood disease with unreliable treatments. Although it is not known what causes it for certain, we do know that life stressors may make the disease worse or…
- Conditions
- Interstitial Cystitis, Mindfulness, Complementary Medicine, Painful Bladder Syndrome
- Trial name
- NCT02457182
- Testing
- Mindfulness-based Stress Reduction (MBSR), Usual medical therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Cardiac Disease, Cancer
Electronic Medical Records and Genomics (eMERGE) Phase III
The Electronic Medical Records and Genomics (eMERGE) Network is in its third phase and during this time is enrolling and sequencing 25,000 individuals on a custom sequencing panel of clinically relevant, actionable genes.
- Conditions
- Cardiac Disease, Cancer, Hypercholesterolemia, Diabetes
- Trial name
- eMERGE (NCT03394859)
- Volunteers
- 25,380 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Renal Stones
Treatment of Renal Stones With Frankincense (Luban)
Frankincense, or olibanum, is the oleogum resin that is harvested from several different trees, an aromatic resin obtained from trees of the genus Boswellia.
- Trial name
- Luban (NCT03924596)
- Testing
- AKBA-Incense (3-acetyl-11-keto-ß-boswellic acid), Potassium Sodium Hydrogen Citrate
- Where
- Oman
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sultan Qaboos University
Incontinence, Urinary
Clinical Study Investigating Safety and Performance of a New Urinary Intermittent Catheters in Healthy Volunteers
The aim of the study is to test the performance and safety of a newly developed intermittent catheter
- Trial name
- NCT02965105
- Testing
- Coloplast Test Catheter, Speedicath
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Coloplast A/S
Chronic Kidney Diseases
Correlation Between Endoscopic Findings And Helicobacter Pylori Infection In Chronic Kidney Disease Patients
The aim of this study is to 1. Evaluate frequency of H. pylori infection in patients with CKD. 2. Description the gastroduodenal lesions found in patients with chronic kidney disease and correlate it to H.pylori infection.
- Trial name
- NCT05927766
- Testing
- esophagogastroduodenoscopy
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Alzheimer Disease
Pharmacokinetic Properties of Idalopirdine (Lu AE58054) in Subjects With and Without Impaired Kidney Function
The purpose of this study is to evaluate the pharmacokinetics properties of idalopirdine following multiple dosing in patients with renal impairment and compare to those in healthy subjects
- Trial name
- NCT02340195
- Testing
- Idalopirdine (Lu AE58054) 60 mg
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Urinary Tract Infections
Decreasing Catheter-Associated Urinary Tract Infections in the Pediatric Intensive Care Unit
The purpose of this study is to identify risk factors associated with indwelling urinary catheters, as well as to assess the nurses' knowledge and adherence to hospital policies.
- Trial name
- NCT00672503
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Diabetes, Diabetic Kidney Disease
Effect of Acute Hypoxia on Renal Hemodynamic in Healthy Volunteers, Patients With Diabetes and Patients With Diabetes and Kidney Disease
Diabetes mellitus is a non-transmissible disease whose incidence is growing worldwide . This pathology is defined by a chronic hyperglycaemia linked to a deficiency of either insulin secretion or its action or both.
- Conditions
- Diabetes, Diabetic Kidney Disease, Hypoxia, Healthy Volunteer
- Trial name
- DIAKIPOX (NCT06846034)
- Testing
- Hypoxia administration study group, Renal clairance study
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Normal Renal Function, Impaired Renal Function
Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011
The purpose of this study is to characterize the PK and safety profile of LEE011 following a single oral dose in adult subjects with various degrees of renal impairment compared to a matched group of healthy subjects with normal…
- Trial name
- NCT02431481
- Testing
- LEE011
- Where
- 4 sites in United States, Bulgaria and 2 more
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Healthy, Enteric Hyperoxaluria
Safety and Tolerability of FB-001 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria
This Phase 1, first-in-human, randomized, double-blinded, placebo controlled study is evaluating FB-001 in healthy volunteers (Part 1) and participants diagnosed with enteric hyperoxaluria (Part 2).
- Trial name
- NCT05650112
- Testing
- FB-001
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Federation Bio Inc.
Urinary Incontinence, Quality of Life
Effect of HIFEM® Treatment of Urinary Incontinence in Women in Primary Care. A Randomized Controlled Trial
Urinary incontinence (UI) is a condition with involuntary leakage of urine. UI has a significant impact on health related quality of life, poorer sleep quality and sexual function, reduced participation in social and physical…
- Conditions
- Urinary Incontinence, Quality of Life, Menopause, Mental Health Issue
- Trial name
- NCT06485167
- Testing
- HIFEM- chair
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Chronic Kidney Disease, Hypertension
Arterial Stiffness in Children and Young People With Hypertension and Chronic Kidney Disease
Age related stiffening and hardening of the arteries is often a slow process, but some conditions such as chronic kidney disease (CKD), seem to increase the rate at which the arteries stiffen even during childhood.
- Trial name
- ART-KIDS (NCT07768865)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- King's College London
Delayed Graft Function
Correlation of Molecular Biomarkers With Biopsy Findings and Outcomes in Renal Transplant Recipients
This is a single-center, prospective, non-randomized, observational study to evaluate specific proteogenomic biomarker panels for acute rejection (AR) and chronic allograft nephropathy/interstitial fibrosis and tubular atrophy…
- Trial name
- NCT02463253
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Hyponatremia
Saline Infusion Test in Hyponatremia
Observational study of biochemical volume biomarker levels in response to a standardized intravenous isotonic saline infusion in patients with hyponatremia.
- Trial name
- SITH (NCT06498856)
- Testing
- Isotonic saline infusion
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Diabetes Mellitus, Renal Failure
The Effects of Hemodialysis on Serum Sclerostin Levels
Background: Parathyroid hormone (PTH) and 1,25-dihydroxy vitamin D (1,25-OHD) as well as mineral bone metabolism modulators like sclerostin are thought to play an important role in in diabetic patients with chronic renal failure.
- Conditions
- Diabetes Mellitus, Renal Failure, Hemodialysis Access Failure
- Trial name
- sclerostin (NCT03952819)
- Testing
- serum sclerostin
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Urinary Incontinence, Quality of Life
Bladder Training in Radical Prostatectomy
Radical prostatectomy is the gold standard in the treatment of patients with localized prostate cancer. Urinary incontinence, which is common after surgery, can affect the quality of life of men negatively.
- Conditions
- Urinary Incontinence, Quality of Life, Lower Urinary Tract Symptoms
- Trial name
- NCT04628351
- Testing
- Bladder Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Non Muscle Invasive Bladder Cancer, Non-Muscle Invasive Bladder Urothelial Carcinoma
Analytical Specificity of Bladder EpiCheck Test in Healthy Population and Urology Patients Without Prior History or Evidence of Bladder Cancer
This is a prospective study to establish the analytical specificity of Bladder EpiCheck test in urine samples from healthy population and urology patients without prior history or evidence of bladder cancer.
- Trial name
- NCT06020807
- Testing
- Bladder EpiCheck
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Nucleix Ltd.
Chronic Kidney Diseases, Magnetic Resonance Imaging
Material Balance Study of TQ-B3525
A clinical study to investigate the absorption, metabolism and excretion of [14C] TQ-B3525 in Chinese adult male healthy subjects, aiming to quantitatively analyze the total radioactivity in the excreta of male healthy subjects…
- Trial name
- NCT05675202
- Testing
- TQ-B3525
- Where
- China
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
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