Clinical trials: Urology
Urology
Preoperative Outreach to Improve Surgical Attendance
This study aims to evaluate the impact of reminder call intervention on no-shows for urologic procedures in patients identified to be high risk for no-showing.
- Trial name
- NCT07644819
- Testing
- Preoperative Outreach
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of California, San Francisco
Urology, Pediatric Disorder
Pelvic Floor Muscle Training and Dynamic Neuromuscular Stabilization Exercises in Pediatric Patients
Dysfunctional voiding (DY) is one of the most common conditions in children. Various treatments are available. Participants will be randomly assigned to either PFMT (Group I) or PFMT+DNS (Group II).
- Trial name
- NCT07267364
- Testing
- PFMT
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Urology, Urinary Bladder, Overactive
Ambulatory Long Length URodynamics Evaluation
A prospective, open-label, single arm interventional trial evaluating the safety and performance of the in-clinic and extended monitoring of the lower urinary tract using the Glean Urodynamics System.
- Conditions
- Urology, Urinary Bladder, Overactive, Benign Prostatic Hyperplasia, Urodynamics
- Trial name
- ALLURE (NCT07425015)
- Testing
- Glean Urodynamics System
- Where
- 9 sites in United States
- Volunteers
- 101 people
- Sponsor
- Bright Uro
Cancer, Urology
Monitoring Treatment Response With Urine and Serum Metabolome Markers in Patients Treated With Novel Hormone Therapy and Have Either Hormone Sensitive Metastatic Prostate Cancer or Disease Progression on Treatment.
80% of patients with newly diagnosed metastatic hormone sensitive prostate cancer have bone metastases. There are mutations that are described with early disease progression when on hormone therapy for prostate cancer.
- Trial name
- Metabolome-PC (NCT07837063)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- The Clatterbridge Cancer Centre NHS Foundation Trust
Robotic Surgical Procedures in Pediatric Urology
Versius Paediatrics Study
This is prospective, multi-phase, single arm, multi-centre, multi-surgeon feasibility clinical trial to provide proof of concept and clinical evidence regarding the safety and efficacy of Versius (robotic surgery medical device)…
- Trial name
- NCT06539442
- Testing
- Versius Surgical System
- Where
- 3 sites in United Kingdom
- Volunteers
- 150 people
- Sponsor
- CMR Surgical Ltd
Prostate Cancer, Urology
A Single-arm, Multicenter Prospective Study to Evaluate the Diagnostic Performance of PROSTest in Men With PSA ≥ 3ng/ml Using Biopsy as the Sole Ground Truth
This prospective observational study will enroll men referred for prostate biopsy due to elevated PSA and/or abnormal digital rectal examination, with or without pre-biopsy MRI.
- Conditions
- Prostate Cancer, Urology, Prostate Cancer (Diagnosis)
- Trial name
- PROSTest_STRAT (NCT07454603)
- Testing
- PROSTEST
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Wren Laboratories LLC
Urology, Urological Diseases
RUTISS-Diary and RUTISS-65 Study
Existing patient-reported outcome measures assess acute urinary tract infection but do not support daily symptom tracking in recurrent UTI (rUTI) or meet the needs of older adults.
- Conditions
- Urology, Urological Diseases, Patient Satisfaction, Pain, Chronic
- Trial name
- NCT07698041
- Testing
- Non-interventional Patient Reported Outcome Measure Development (RUTISS-Diary), Non-interventional Patient Reported Outcome Measure Development (RUTISS-65)
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Katherine Finlay
Chronic Kidney Disease, Pediatric Urology
Safety of Short-course of NSAIDs in Pediatric Patients With CKD
The purpose of this study is to determine if non-steroidal anti-inflammatory (NSAID) use in the postoperative setting increases the risk of acute kidney injury (AKI) in pediatric patients with mild-to-moderate chronic kidney…
- Trial name
- NCT06860711
- Testing
- NSAIDs
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- University of Colorado, Denver
Urology
Artificial Intelligence (AI)-Based Intraoperative Visualization is Increasingly Integrated Into Robotic Surgery Platforms; However, Its Impact on Surgeons' Cognitive Workload Remains Unclear. This Study Evaluated Perceived Workload Among Console Surgeons and Bedside Assistants According to Different
Robotic surgery is now widely adopted in urology, and the da Vinci Single-Port (SP) platform enables complex procedures through a single multichannel incision, with favorable perioperative and outpatient outcomes in selected…
- Trial name
- NCT07566078
- Testing
- Yolo
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Urology, Urodynamics
The Glean Registry
A registry designed to collect real-world data (RWD) on the Glean Urodynamics System via a retrospective medical chart review.
- Trial name
- NCT07558655
- Testing
- Glean Urodynamics System
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Bright Uro
Pediatric Urology
Diagnostic Performance of PIC Cystogram vs VCUG in Children
The goal of this interventional diagnostic clinical trial is to evaluate and compare the diagnostic effectiveness of PIC cystography and voiding cystourethrography (VCUG) for the detection of vesicoureteral reflux (VUR) in…
- Trial name
- NCT07334821
- Testing
- PIC cystography, VCUG
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tarik Emre Sener
Surgery, Post Operative Complications
Enhanced Vitals Monitoring After Major Surgery Trial
The aim of this clinical trial is to examine the feasibility of an enhanced vital sign monitoring solution in-hospital and at-home. This study includes adult patients undergoing inpatient major vascular or abdominal surgery.
- Conditions
- Surgery, Post Operative Complications, Quality of Recovery, General Surgery
- Trial name
- NCT06584825
- Testing
- Enhanced Vitals Monitoring
- Where
- 2 sites in Canada
- Volunteers
- 110 people
- Sponsor
- University of British Columbia
Urologic Injuries, Urology
The Clinical Research of Traditional Chinese Medicine Compound Formulas
To observe the efficacy and safety of Shenkangling, a traditional Chinese medicine decoction, for renal ischemia-reperfusion injury, and to provide evidence-based medical evidence and ideas for clinical therapeutic use.
- Trial name
- NCT07153731
- Testing
- Shenkangling
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Urology
Efficacy and Safety of Two Bladder-preserving Treatment Durations With Disitamab Vedotin Plus Toripalimab Combination in Her2-expressing Muscle-invasive Bladder Cancer: A Phase II, Open-Label, Randomized Clinical Trial
This study aims to evaluate the efficacy of disitamab vedotin combined with toripalimab as a bladder-preserving treatment combination in patients with HER2 positive locally advanced MIBC, including one year bladder-intact DFS…
- Trial name
- NCT07151560
- Testing
- 6 cycle RC48 and JS001, 12 cycle RC48 and JS001
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Hypospadias, Pediatric Urology
Can a Platelet-Rich Plasma Covering Layer Reduce Urethrocutaneous Fistula Rate After Distal Penile Hypospadias Repair Using the STAR Technique: A Randomized Controlled Trial
Methods We conducted a prospective randomized controlled study at the Pediatric Urology Department of Cairo University Specialized Pediatric Hospital between July 2024 and January 2025 .
- Trial name
- NCT07006922
- Testing
- hypospadias repair using the STAR technique with PRP as protective layer, hypospadias repair using the STAR technique
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Cairo University
Pediatric Urology, Ureteropelvic Junction Obstruction
Pediatric Robotic Versus Open Pyeloplasty
The objective is conduct a pilot randomized controlled trial comparing robotic and open techniques for surgical correction of congenital UPJ obstruction (pyeloplasty) in pediatric patients.
- Trial name
- NCT04884945
- Testing
- Open Pyeloplasty (OP), Robotic-Assisted Laparoscopic Pyeloplasty (RALP)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Indiana University
Dysfunctional Voiding, Bladder Dysfunction
Linguistic Validation of the Childhood Bladder and Bowel Dysfunction Questionnaire (CBBDQ) for 5-12 Years Old in Korean
The study is to conduct a linguistic and cultural validation of the Children Bladder and Bowel Dysfunction (CBBDQs) for 5-12 years old from English to Korean.
- Conditions
- Dysfunctional Voiding, Bladder Dysfunction, Bowel Dysfunction, Pediatric Urology
- Trial name
- NCT04490642
- Testing
- Questionnaire
- Where
- 3 sites in South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Quality of Recovery, Urology
Postoperative Recovery and Comfort in Patients Undergoing Urologic Robotic Surgery
Previously published studies show that adding intrathecal morphine to general anesthesia can reduce the postoperative pain and length of stay (LOS) in varies types of surgery.
- Conditions
- Quality of Recovery, Urology, Pain, PONV
- Trial name
- NCT04694950
- Testing
- Usual care
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Linkoeping University
Urology
The Use of Videoconferencing for Monitoring of Patients Post Urologic Surgery
Our study would be the first randomized study investigating the use of video conferencing via tablet computers versus traditional bedside rounding and its effect on clinical data such as length of stay and complications as well…
- Trial name
- NCT02771431
- Testing
- Tele-rounding in post operative care
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Pediatric Outpatients Encountered in Three Specialty Clinics, i.e. Respirology, Gastroenterology, and Genito-urology
Effects of Expert Arbitration on Clinical Outcomes When Disputes Over Diagnosis Arise Between Physicians and Their Artificial Intelligence Counterparts: a Randomized, Multicenter Trial in Pediatric Outpatients
We have recently developed an artificial intelligence (AI) framework to diagnose common pediatric diseases. This randomized controlled clinical trial aims to investigate the effects of expert arbitration on clinical outcomes in…
- Trial name
- NCT04011761
- Testing
- expert arbitration over discordant diagnoses made by AI diagnostic system and human doctors, respectively
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Guangzhou Women and Children's Medical Center