Clinical trials: Urologic Surgical Procedure
Low Dose of Pethidine for Subarachnoid Anesthesia
Assessment of Subarachnoid Anesthesia With Low Dose of Pethidine and Combination of Ropivacaine With Fentanyl for Urologic Surgical Operations.
The aim of this study is to assess the efficacy of subarachnoid anesthesia with low dose of pethidine (0.4mgkg-1) compared to administration of ropivacaine and fentanyl which is nowadays the common practice.
- Trial name
- NCT03260283
- Testing
- Pethidine hydrochloride, Ropivacaine HCl Inj 7.5 MG/ML, Fentanyl
- Where
- Greece
- Volunteers
- 104 people
- Sponsor
- Saint Savvas Anticancer Hospital
Urinary Incontinence, Pelvic Floor Disorders
Pubourethral Ligament Plication for the Surgical Treatment of Stress Urinary Incontinence
To test efficacy and safety at six months of the proposed Pubourethral Plication Procedure (PPP) for cure of stress urinary incontinence - reinforcing pubourethral ligaments (PUL) with large diameter polyester sutures.
- Trial name
- NCT05733052
- Testing
- Polyester suture
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Muğla Sıtkı Koçman University
Anesthesia, Local
Analgesic Efficacy of Lidocaine Plus Bupivacaine Versus Bupivacaine Alone Caudally
Optimal analgesia following ambulatory surgery is an important matter for patient satisfaction and it reduces unnecessary hospital admissions.
- Trial name
- NCT03911648
- Testing
- 0.5 ml.kg-1 bupivacaine 0.25%, 0.5 ml.kg-1 bupivacaine 0.25% with the addition of 3 mg/kg lidocaine 1%
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Ayancık State Hospital
Renal Cell Cancer
A Study Evaluating the Effect of Pembrolizumab (MK-3475) in Participants With Renal Cell Cancer (MK-3475-031)
This study will examine the effect of treatment with the neoadjuvant antibody pembrolizumab (MK-3475) on tumors of participants with renal cell cancer (RCC).
- Trial name
- NCT02212730
- Testing
- Pembrolizumab Pre-Resection, Surgical Resection, Pembrolizumab Post-Resection
- Volunteers
- 10 people
- Sponsor
- Merck Sharp & Dohme LLC
Pelvic Organ Prolapse, Urinary Incontinence
Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures
This is a randomized controlled trial to determine if there is a difference between chlorhexidine gluconate and povidone iodine vaginal preparations for urogynecological surgery post operative infections.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Pelvic Floor Disorders, Gynecologic Disease
- Trial name
- CLNUP (NCT04048356)
- Testing
- Vaginal scrub, to be applied vaginally and perineally immediately prior to surgery.
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Chronic Kidney Disease Stage 5, Periodontitis
Effect of Non-surgical Periodontal Treatment and C-reactive Protein Levels in Hemodialysis Patients
The presence of periodontitis has been hypothesized as a risk factor for several systemic outcomes, including chronic kidney disease (CKD).
- Trial name
- NCT04262011
- Testing
- immediate treatment, postponed treatment
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- Universidade Federal de Santa Maria
Renal Tumors
A Multicenter Study of RUS NE
This sponsor-initiated, randomized controlled clinical trial aims to demonstrate the clinical efficacy of RUS NE Surgical Navigation System in patients undergoing robotic-assisted partial nephrectomy.
- Trial name
- NCT06868186
- Testing
- RUS NE
- Where
- 4 sites in South Korea
- Volunteers
- 204 people
- Sponsor
- Hutom Corp
Acute Kidney Injury (AKI)
Observational Study to Evaluate the Epidemiology of Surgical-induced Acute Kidney Injury
The evaluation of an accurate occurrence rate for AKI is of great importance for health policy, quality initiatives as well as for designing clinical trials.
- Trial name
- Epis-AKI (NCT04165369)
- Where
- 82 sites in United States, Egypt and 12 more
- Volunteers
- 10,568 people
- Sponsor
- University Hospital Muenster
Renal Stone
Prospective Assessment of Procedure-Related and Patient-Reported Outcomes After Retrograde Intrarenal Surgery (RIRS) for Renal Calculi Less Than 20 mm
The investigators aim at this study to prospectively assess procedure-related outcomes after RIRS for renal calculi less than 20 mm, including stone free rate (SFR), predictors of successful outcome, complications types/rate…
- Trial name
- NCT03719456
- Testing
- Retrograde Intrarenal Surgery
- Where
- 2 sites in Egypt
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Tumor, Nephrectomy
Laparoscopic Versus Open Partial Nephrectomy - Surgical and Oncological Outcomes
Partial Nephrectomy is the standard care for small (<4 cm) renal tumors. Despite the expanding use of laparoscopic approach, debate exist regarding the short and long term outcomes compared to the open approach.
- Conditions
- Tumor, Nephrectomy, Laparoscopy
- Trial name
- LapVsOpen prtn (NCT01093079)
- Testing
- Laparoscopic partial nephrectomy, Open partial nephrectomy
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rabin Medical Center
Catheter-Related Infections, Urinary Tract Infections
Foley Catheter vs a Self-contained Valved Urinary Catheter
The purpose of this study is to compare UTI rates and patient satisfaction associated with indwelling Foley catheter verses a valved catheter in patients who are being discharged home with a catheter after urogynecologic…
- Conditions
- Catheter-Related Infections, Urinary Tract Infections, Urogynecologic Surgery
- Trial name
- NCT03178734
- Testing
- Foley Catheter vs Self-Contained Valved Catheter
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- charbel salamon
Overactive Bladder, Pelvic Organ Prolapse
The Effect of an Additional Stress Incontinence Procedure on Overactive Bladder During Pelvic Organ Prolapse Repair
Pelvic organ prolapse (POP) is a common condition in women. Approximately 20% of women undergo surgical correction for POP in their lifetime.
- Trial name
- NCT02502838
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obstetric Fistula, Fistula
Effectiveness and Acceptability of Insertable Devices for Obstetric Fistula Management
The investigators propose a clinical trial and nested qualitative study to 1) quantify the effectiveness of an insertable vaginal cup to manage fistula urinary incontinence, 2) examine user and implementer acceptability, and 3)…
- Conditions
- Obstetric Fistula, Fistula, Fistula, Urinary, Fistula, Vaginal
- Trial name
- COPE (NCT05444504)
- Testing
- Cup, Cup+
- Where
- 3 sites in Ghana, Kenya
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Urological Manifestations, Anesthesia
Optic Nerve Sheath Diameter in Urologic Surgery
The investigators aimed to determine intracranial pressure changes during spinal and general anesthesia by using optic nerve sheath diameter and near infrared spectrometer in urologic surgery patients in lithotomy position.
- Trial name
- NCT05846555
- Testing
- urologic surgery
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Inflammatory Response, Chronic Renal Disease
Hemadsorption During and After Cardiopulmonary Bypass to Modulate the Inflammatory Response
Chronic kidney disease (CKD) is a risk factor for the development of cardiovascular disease, which increases the risk of death after cardiac surgery.
- Conditions
- Inflammatory Response, Chronic Renal Disease, Cardiac Surgery
- Trial name
- IMHeS (NCT04157647)
- Testing
- CytoSorb, Control
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University Magna Graecia
Bladder Cancer, Cystectomy
Patient-Centered Surgical Prehabilitation
The purpose of this research is to validate the prehabilitation program which is defined as a set of interventions meant to prepare the body physically and nutritionally for the cystectomy procedure.
- Trial name
- Prehab (NCT05715684)
- Testing
- Exercise Training, Nutritional Intervention
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Adenocarcinoma, Prostate Neoplasms
Use of Tracking Devices to Locate Abnormalities During Invasive Procedures
This study will evaluate the accuracy and effectiveness of an experimental tracking device for locating abnormalities during invasive procedures, such as biopsy or ablation, that cannot easily be visualized by usual imaging…
- Conditions
- Adenocarcinoma, Prostate Neoplasms, Prostate Cancer, Renal Cell Carcinoma
- Trial name
- NCT00102544
- Testing
- EM Tracking
- Where
- United States
- Volunteers
- 3,894 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Kidney Transplantation, Pancreas-kidney Transplantation
Protocol DIVAT-Uro
The aim of project DIVAT-URO (Données Informatisées et Validées en Transplantation - Urology) is to organize a thematic network in urology traced on NetWork DIVAT to supplement the medical and biological data of DIVAT existing…
- Trial name
- NCT01280708
- Testing
- Capture data
- Where
- France
- Volunteers
- 1,616 people
- Sponsor
- Nantes University Hospital
Perioperative Complication
Exercise in Patients Undergoing Urologic Surgery
Patients who are being scheduled for an operative procedure with an inpatient postoperative stay are eligible for this study. Participants will be selected to start a physical fitness plan or a nutrition plan at the time of…
- Trial name
- NCT03954678
- Testing
- Exercise Group, Nutrition Group
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Emory University
Renal Cell Carcinoma
Pucotenlimab Combined With Lenvatinib as a Neodjuvant Therapy for Non Clear Cell Renal Cell Carcinoma
Through the neoadjuvant treatment with a combination of Pucotenlimab and Lenvatinib, it eventually enables the successful and safe implementation of partial nephrectomy in patients with localized renal cancer, who have…
- Trial name
- NCT06129955
- Testing
- Pucotenlimab Combined With Lenvatinib
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Sun Yat-sen University