Clinical trials: Urolithiasis
Ureteral Double-J Stent, Urolithiasis
Evaluation of Quality of Life in Patients After Placement of a Modified Double J Ureteral Stent
Double-J (DJ) stents are commonly inserted after ureteroscopy. There are several complications associated with the presence of DJ stent: urinary tract infection, stent encrustation, stent migration, and stent-related symptoms…
- Conditions
- Ureteral Double-J Stent, Urolithiasis, Quality of Life
- Trial name
- NCT07275879
- Testing
- Ureteric stent insertion
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- St. Luke's Clinical Hospital, Russia
Kidney Stones, Nephrolithiasis
6.3Fr Versus 7.5Fr Mini-Flexible Ureteroscopy for Renal Stones (MINI-FURS)
This prospective, randomized, single-blinded, non-inferiority clinical trial will compare the clinical outcomes and cost-effectiveness of two mini-flexible ureteroscopes (6.3Fr and 7.5Fr) used during flexible ureteroscopy for the…
- Conditions
- Kidney Stones, Nephrolithiasis, Renal Calculi
- Trial name
- MINI-FURS (NCT07798336)
- Testing
- 6.3Fr Mini-Flexible Ureteroscope, 7.5Fr Mini-Flexible Ureteroscope
- Where
- Canada
- Volunteers
- 308 people
- Sponsor
- Sault Area Hospital
Urolithiasis, Stone Ureter
A Randomized Clinical Trial to Evaluate the Effectiveness of Oral Potassium Citrate in Preventing Ureteral Stent Encrustation in Patients Undergoing Ureteroscopy for Uric Acid Kidney Stones
This randomized clinical trial aims to evaluate the efficacy of oral potassium citrate in reducing ureteral stent encrustation following ureteroscopy for uric acid kidney stones.
- Trial name
- NCT06819553
- Testing
- Oral Potassium Citrate
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Zagazig University
Acidosis, Renal Tubular, Nephrolithiasis
Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal Renal Tubular Acidosis
Purpose 1. To compare the performance of the two currently employed urinary acidifications tests in stone formers, the furosemide/fludrocortisone and ammonium chloride loading test. 2.
- Conditions
- Acidosis, Renal Tubular, Nephrolithiasis, Vacuolar Proton-Translocating ATPases
- Trial name
- NCT01690039
- Testing
- Furosemide-Fludrocortisone-Test (test for urinary acidification)
- Where
- Switzerland
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Kidney Stone
Comparing Pneumatic Versus Ultra-sonic Percutaneous Nephrolithotomy in Large Kidney Stones
The purpose of this study is to determine which type of percutaneous nephrolithotomy is better in large kidney stones
- Trial name
- NCT02751281
- Testing
- Pneumatic percutaneous nephrolithotomy, Ultra-sonic percutaneous nephrolithotomy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Nephrolithiasis, Pediatric Nephrolithiasis
Tubeless vs Tube PCNL in Pediatric Nephrolithiasis
This study is designed to compare two surgical techniques for removing kidney stones in children and adolescents (ages 6-18 years).
- Trial name
- TUBELESS (NCT07183930)
- Testing
- Tubeless Percutaneous Nephrolithotomy (PCNL), Standard Tube Percutaneous Nephrolithotomy (PCNL)
- Where
- Pakistan
- Volunteers
- 640 people
- Sponsor
- Lady Reading Hospital, Pakistan
Urolithiasis, Proximal Ureteral Stone
Efficacy of Semi-rigid Ureteroscopic Laser Lithotripsy in the Treatment of Proximal Ureteral Stones: a Randomized Controlled Trial
The efficacy of Ho: YAG and TFL combined with semirigid ureteroscopic treatment of proximal ureteral stones will be compared.
- Trial name
- NCT06489366
- Testing
- Thulium Fiber laser (TFL) lithotripsy, Ho: YAG lithotripsy
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Zhongnan Hospital
Renal Stone
Comparison Between External Oblique Intercostal Block and Erector Spinae Plane Block in PCNL
The aim of the study is to compare the post-operative analgesic effect of USG unilateral External oblique intercostal (EOI) block with Erector spinae plane block (ESPB) for after percutaneous Nephrolithotomy with a hypothesis…
- Trial name
- NCT06131151
- Testing
- External Oblique Intercostal Block, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assiut University
Urolithiasis
Urine Biomarker for Stone Recurrence
Despite the advent of treating stones with Extracorporeal Shock Wave Lithotripsy (ESWL) and Percutaneous nephrolithotomy (PCNL), the recurrence rate for renal stones remains high and this may be due to poor compliance of patients…
- Trial name
- NCT04354181
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Urolithiasis
Study of Tomography of Nephrolithiasis Evaluation
This is a multi-center, randomized controlled trial of ultrasonography (ultrasound) compared to computed tomography (CT) for the initial emergency room evaluation of patients with suspected renal colic.
- Trial name
- STONE (NCT01451931)
- Testing
- Point-of-care Ultrasound, Radiology Ultrasound, Radiology CT
- Where
- 15 sites in United States
- Volunteers
- 2,776 people
- Sponsor
- University of California, San Francisco
Kidney Stone
Comparison of Efficacy of Intercostal Nerve Block vs Peritract Infiltration With 0.25% Bupivacaine in PCNL
Percutaneous nephrolithotomy (PCNL) is the preferred treatment for renal stones >2 cm or resistant to ESWL. Postoperative pain following this invasive surgery adds to the morbidity of patient which requires additional analgesia…
- Trial name
- NCT04835922
- Testing
- Intercostal Nerve Block, Peritract Infiltration
- Where
- Nepal
- Volunteers
- 60 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Other Specified Disorders of Kidney and Ureter, Benign Neoplasm of Ureter
Spinal Morphine or Intravenous Lidocaine in Robot-assisted Upper Urologic Surgery
The goal of this clinical trial is to learn whether the addition of spinal analgesia leads to superior recovery in patients undergoing robotic-assisted laparoscopic upper urinary tract surgery under general anesthesia.
- Conditions
- Other Specified Disorders of Kidney and Ureter, Benign Neoplasm of Ureter, Calculus of Kidney and Ureter, Ureter Cancer
- Trial name
- SMILe (NCT06349668)
- Testing
- spinal analgesia with morphine and bupivacaine, lidocaine infusion
- Where
- 3 sites in Sweden
- Volunteers
- 220 people
- Sponsor
- Hans Bahlmann
Nephrolithiasis
Intraoperative Cone-beam CT for Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is a first-line treatment for kidney stones >2cm. Frequently, patients require multiple procedures to address their stone burden.
- Trial name
- NCT04556396
- Testing
- Cone beam CT
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Loyola University
Urolithiasis, Hyperoxaluria
Spot Urine Oxalate to Creatinine Ratio and 24 Hours Urinary Oxalate
The evaluation of 24 hour urinary oxalate excretion is the gold standard for diagnosing Hyperoxaluria in patients with recurrent urolithiasis.
- Trial name
- NCT04571359
- Testing
- Oxalate to creatinine ratio
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Aga Khan University
Urolithiasis, Kidney Stone
Effects of Virtual Reality Education on Anxiety and Learning in Patients Undergoing Urolithiasis Surgery
This randomized controlled trial aims to evaluate the effects of two-tier virtual reality-based preoperative education on anxiety, learning knowledge, self-care ability, and cognitive load in patients undergoing urolithiasis…
- Conditions
- Urolithiasis, Kidney Stone, Ureter Stones
- Trial name
- VR-URO (NCT07620873)
- Testing
- VR Education, Two-Tier VR Education
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Wei-Lin, Huang
Kidney Stones
AR Projections for Eye-gaze Evaluation in Phantoms
This project aims to develop an augmented reality (AR) tool to enhance skill acquisition for endoscopic kidney stone surgery. Of the 100,000 patients who undergo an endoscopic kidney stone treatment annually in the United States…
- Trial name
- NCT07161024
- Testing
- Augmented reality
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Urolithiasis, Stones, Kidney
Stone Clearance With Aspiration vs Other Technologies: a Real-world Evidence Study
The goal of this clinical trial is to evaluate the effectiveness and safety of Steerable Ureteroscopic Renal Evacuation (SURE) with the CVAC System versus other commonly used renal-stone interventions.
- Conditions
- Urolithiasis, Stones, Kidney, Renal Stones, Kidney Stones
- Trial name
- SCORE (NCT07155005)
- Testing
- CVAC® SYSTEM, FLEXIBLE AND NAVIGATIONAL URETERAL ACCESS SHEATH (FANS) IN FLEXIBLE URETEROSCOPY (FURS), DIRECT IN-SCOPE SUCTION (DISS) IN FLEXIBLE URETEROSCOPY (FURS)
- Volunteers
- 1,000 people
- Sponsor
- Calyxo, Inc.
Urologic Injuries, Kidney Disease
The Clinical Research of Traditional Chinese Medicine Formula
This study examines the efficacy and safety of Bushen Huoxue Simiao formula for tonifying the kidneys and promoting blood circulation in treating postoperative complications of upper urinary tract stones, thereby providing…
- Trial name
- NCT07746219
- Testing
- Bushen Huoxue Simiao Formula, control group
- Volunteers
- 80 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Urinary Lithiasis
Stone Disease of the Urinary Tract in Children
The incidence of stone disease of the urinary tract in children is increasingly increasing with a remarkable economic impact for its management.
- Trial name
- Ped-Urolithia (NCT06032364)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Strasbourg, France
Symptoms and Signs, Pain
Stent-related Symptoms Comparison: Polaris Loop vs Vortek Double-J Stents
Prospective randomized controlled single-blind parallel-group trial in order to compare symptoms related to loop-tail (Polaris Loop) stents versus conventional double J (Vortek) stents after uncomplicated flexible URS.
- Conditions
- Symptoms and Signs, Pain, Renal Calculi
- Trial name
- NCT03344107
- Testing
- USSQ questionnaire administration after RIRS.
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- A.O.U. Città della Salute e della Scienza