Clinical trials: Urinary Incontinence
Benign Prostatic Hyperplasia, Benign Prostatic Obstruction
Anterior Bridge-Preserving Versus Conventional Early Apical Release in Bipolar Enucleation of the Prostate
Bipolar enucleation of the prostate is an effective operation for men with urinary obstruction caused by a benign enlarged prostate. Some men leak urine for a period after the operation.
- Conditions
- Benign Prostatic Hyperplasia, Benign Prostatic Obstruction, Stress Urinary Incontinence (SUI), Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
- Trial name
- ABPS-EAR-BIPO (NCT07893548)
- Testing
- Anterior Bridge-Preserving Semicircular Early Apical Release (ABP-S-EAR), Conventional Early Apical Release (EAR)
- Volunteers
- 230 people
- Sponsor
- Benha University
Stress Urinary Incontinence (SUI)
A Study to Assess the Safety and Effectiveness of the UrOActive® Artificial Urinary sPHincter (AUS)
Prospective, multicenter, single-arm study
- Trial name
- SOPHIA2 (NCT06968741)
- Testing
- Artificial Urinary Sphincter (AUS)
- Where
- 21 sites in United States, France
- Volunteers
- 140 people
- Sponsor
- UroMems SAS
Urinary Incontinence, Medical Device Discomfort
Tolerance, Use and Performance of the PEASY Urine Collection Device in Hospitalized Patients
At present, 3 types of urine collection device can be distinguished: absorbent devices (diaper-type), penile clamps and penile collection sheaths.
- Trial name
- TUPELO (NCT07028996)
- Testing
- Daily use of the PEASY urine collection device for 5 days, Daily collection of patient feedback using a visual analog scale (0-100)
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer
Multimodal Prehabilitation and Rehabilitation for Men Undergoing Robot-Assisted Radical Prostatectomy
Prostate cancer is the most common cancer in Australian men. Robot-assisted radical prostatectomy (RARP) - surgical removal of the prostate - is a standard treatment, but it frequently causes erectile dysfunction (ED) and urinary…
- Conditions
- Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer, Urinary Incontinence Following Surgical Procedure
- Trial name
- ROBOPREP (NCT07576335)
- Testing
- Tadalafil 5 mg, Pelvic Floor Muscle Training (PFMT), Aerobic Exercise Program
- Where
- 3 sites in Australia
- Volunteers
- 64 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)
Urinary Incontinence (UI), Prostatectomy
Transcutaneous Tibial Nerve Stimulation for Urinary Incontinence After Radical Prostatectomy
Urinary incontinence (UI) after radical prostatectomy (RP) is a common postoperative complication that significantly affects quality of life.
- Trial name
- NCT07742176
- Testing
- Active Transcutaneous Tibial Nerve Stimulation (TTNS), Pelvic Floor Muscle Training (PFMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Pamukkale University
Urinary Incontinence, Mixed Urinary Incontinence
Comparing the Effect of Two Types of Pelvic Floor Muscle Stimulation Devices to Improve Symptoms of Urinary Incontinence in Women.
This randomized, parallel-group, non-inferiority clinical trial will compare electromagnetic chair therapy with standard electrostimulation combined with biofeedback in 58 adult women with mixed urinary incontinence.
- Conditions
- Urinary Incontinence, Mixed Urinary Incontinence, Urinary Incontinence (UI), Stress Urinary Incontinence (SUI)
- Trial name
- ESEMS (NCT07792031)
- Testing
- Electromagnetic chair therapy, Electrical stimulation therapy
- Where
- 2 sites in Argentina
- Volunteers
- 58 people
- Sponsor
- Espacio Gaspar Clinic
Benign Prostatic Hyperplasia, Benign Prostatic Obstruction
Anterior Bridge-Preserving Versus Conventional Early Apical Release During Holmium Laser Enucleation of the Prostate
Holmium laser enucleation of the prostate (HoLEP) is an effective operation for men with urinary obstruction caused by a benign enlarged prostate. Some men leak urine for a period after the operation.
- Conditions
- Benign Prostatic Hyperplasia, Benign Prostatic Obstruction, Stress Urinary Incontinence, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
- Trial name
- ABPS-EAR-HOLEP (NCT07892599)
- Testing
- Anterior Bridge-Preserving Semicircular Early Apical Release (ABP-S-EAR), Conventional Early Apical Release (EAR)
- Volunteers
- 230 people
- Sponsor
- Ahmed Ebrahim Zahran
Urinary Incontinence , Stress, Prostatectomy
Effect of High-Intensity Focused Electromagnetic (HIFEM) Technology in the Treatment of SUI in Chinese Men Undergone Robotic Radical Prostatectomy
This is a prospective, randomized trial to evaluate the efficacy and safety of High-Intensity Focused Electromagnetic (HIFEM) Technology in the treatment of stress urinary incontinence compared with standard of care in Chinese…
- Trial name
- NCT06589869
- Testing
- EM Chair, Standard of care
- Where
- Hong Kong
- Volunteers
- 184 people
- Sponsor
- Chinese University of Hong Kong
Depressive Symptoms, Urinary Incontinence
BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women
The goal of this clinical trial is to evaluate if the combined treatment with EXOMIND (BTL-699-2) and EMSELLA (HPM-6000UF) devices is able to improve depressive symptoms and sexual function in women who are perimenopausal or…
- Conditions
- Depressive Symptoms, Urinary Incontinence, Sexual Dysfunction
- Trial name
- NCT07413705
- Testing
- EXOMIND (BTL-699-2) Active Treatment, EMSELLA (HPM-6000UF) ActiveTreatment
- Where
- 3 sites in United States, Canada
- Volunteers
- 41 people
- Sponsor
- BTL Industries Ltd.
Stress Urinary Incontinence (SUI)
The Effects of Expiratory Muscle Strength Training in Women With Stress Urinary Incontinence
The aim of this study is to investigate the effects of expiratory muscle strength training in addition to pelvic floor muscle training in women with stress urinary incontinence.
- Trial name
- NCT07693920
- Testing
- Pelvic Floor Muscle Training, Expiratory muscle strength training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Mustafa Kemal University
Stress Urinary Incontinence
Autologous Muscle Derived Cells Compared to Placebo for Urinary Sphincter Repair in Post-surgical Female Stress Incontinence
This study evaluates the efficacy and safety of Autologous Muscle Derived Cells for Urinary Sphincter Repair (AMDC-USR; generic name: iltamiocel) compared to a placebo in the reduction of stress incontinence episode frequency in…
- Trial name
- CELLEBRATE (NCT03104517)
- Testing
- AMDC-USR (iltamiocel)
- Where
- 21 sites in United States, United Kingdom
- Volunteers
- 96 people
- Sponsor
- Cook MyoSite
Urinary Incontinence
This Study Will Collect Clinical and Patient Reported Satisfaction Data From Males Requiring Urine Output Management Overnight in the Home Setting.
This post-market study will assess the performance of and user satisfaction with the PureWick® Male External Catheter in a home setting.
- Trial name
- PUREST-M (NCT06850259)
- Testing
- PureWick® Urine Collection System, UltraFlex™ Self-Adhering Male External Catheter
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- C. R. Bard
Stress Urinary Incontinence (SUI)
Pelvic Floor Muscle Exercise and Progressive Muscle Relaxation for Stress Urinary Incontinence
Stress urinary incontinence (SUI) is a common condition in women that causes involuntary urine leakage during activities such as coughing, sneezing, laughing, or exercising.
- Trial name
- NCT07762391
- Testing
- Pelvic Floor Muscle Exercise, Progressive Muscle Relaxation (PMR), Combined Pelvic Floor Muscle Exercise and Progressive Muscle Relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Urinary Incontinence (UI)
Clinical, Functional, and Therapeutic Characterization of Women With Urinary Incontinence and Analysis of Factors Associated With Treatment Response
The goal of this observational retrospective study is to characterize women with urinary incontinence and to identify factors associated with their response to treatment using artificial intelligence models.
- Trial name
- NCT07887464
- Testing
- Artificial intelligence clinical decision support model
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Javier Pereira
Urinary Incontinence, Urge, Urinary Bladder, Overactive
INTIBIA Pivotal Study
Prospective, randomized, double-blind, multicenter study to evaluate the safety and efficacy of an implantable tibial nerve stimulator in subjects with urgency urinary incontinence (UUI).
- Conditions
- Urinary Incontinence, Urge, Urinary Bladder, Overactive, Urinary Bladder Diseases, Urologic Diseases
- Trial name
- NCT05250908
- Testing
- INTIBIA Therapeutic, INTIBIA Non-Therapeutic
- Where
- 22 sites in United States, Netherlands
- Volunteers
- 208 people
- Sponsor
- Coloplast A/S
Stress Urinary Incontinence
Second-generation Radiofrequency Application and Therapeutic Exercise for Stress Urinary Incontinence
Stress urinary incontinence (SUI) is defined as the loss of the ability to hold urine after exertion, i.e., as a result of imbalances in intra-abdominal pressure, which directly affect the lower urinary tract.
- Trial name
- NCT07095283
- Testing
- Short International Consultation on Incontinence Questionnaire (ICIQ-SF), King's Health Questionnaire (KHQ), Ultrasound evaluation
- Where
- Spain
- Volunteers
- 239 people
- Sponsor
- Cardenal Herrera University
Urge Urinary Incontinence
Post Approval Effectiveness and Durability Evaluation of the Altaviva™ Tibial Device
The purpose of this prospective, multicenter study is to assess the long-term safety and effectiveness of the Altaviva™ system for the treatment of UUI
- Trial name
- ENDURANCE™ (NCT07456865)
- Testing
- Altaviva™ system
- Where
- 19 sites in United States
- Volunteers
- 256 people
- Sponsor
- MedtronicNeuro
Pelvic Organ Prolapse, de Novo Stress Urinary Incontinence
CREDE Study: Intraoperative Crede Manoeuver Compared to Preoperative Prolapse Reduction Stress Test to Predict Postoperative de Novo Stress Urinary Incontinence (PONSUI) at the Time of Pelvic Organ Prolapse (POP) Surgery
The CREDE pilot randomized study will compare the intraoperative Crede manoeuver (M1) to preoperative prolapse (POP) reduction cough stress test (M2) for the prediction and prevention of PONSUI.
- Conditions
- Pelvic Organ Prolapse, de Novo Stress Urinary Incontinence, Stress Urinary Incontinence
- Trial name
- NCT04087642
- Testing
- Intraoperative Crede manoeuver, Preoperative prolapse reduction cough stress test
- Where
- 2 sites in Canada
- Volunteers
- 25 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Overactive Bladder, Urge Incontinence
A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)
A prospective, multicenter, single-arm study to evaluate the safety and effectiveness of the eCoin® implanted tibial nerve stimulator in subjects with urgency urinary incontinence (UUI).
- Conditions
- Overactive Bladder, Urge Incontinence, Incontinence, Urinary, Urinary Urge Incontinence
- Trial name
- RECIPE (NCT05685433)
- Testing
- eCoin Tibial Nerve Stimulation
- Where
- 22 sites in United States
- Volunteers
- 200 people
- Sponsor
- Valencia Technologies Corporation
Urinary Urge Incontinence, Stress Urinary Incontinence
Surface Electrical Stimulation for Urinary Incontinence in Men Treated for Prostate Cancer
Background: Men who are treated for prostate cancer often develop urinary leakage (incontinence). An experimental device that uses electrical impulses to stimulate pelvic floor muscles and surrounding tissues may help.
- Conditions
- Urinary Urge Incontinence, Stress Urinary Incontinence, Prostatic Hyperplasia
- Trial name
- NCT06161506
- Testing
- Elidah Device
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- National Cancer Institute (NCI)