Clinical trials: Urinary Diversion
Recurrent Bladder Cancer, Stage 0 Bladder Cancer
Urinary Diversion During Robotic Assisted Radical Cystectomy in Patients With Bladder Cancer
This randomized clinical trial studies intracorporeal or extracorporeal urinary diversion during robotic assisted radical cystectomy in reducing complications in patients with bladder cancer.
- Conditions
- Recurrent Bladder Cancer, Stage 0 Bladder Cancer, Stage I Bladder Cancer, Stage II Bladder Cancer
- Trial name
- NCT02252393
- Testing
- robot-assisted laparoscopic surgery, intraoperative complication management/prevention, quality-of-life assessment
- Sponsor
- Case Comprehensive Cancer Center
Ureteral Obstruction, Urinary Diversion
Early Infancy Ureteral Reimplantation for Distal Ureteral Obstruction
Prospective multicenter observational study of early infancy ureteral reimplantation for distal ureteral obstruction. The study is an observation study since the investigators will not assign specific interventions to the…
- Trial name
- NCT02419339
- Testing
- Extravesical ureteral reimplantation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Nebraska
Neurogenic Bladder, Continent Cutaneous Urinary Diversion
Implantation of Continent Catheterizable Channel : Native Bladder or Enterocystoplasty ?
PURPOSE. To compare the results between two sites of implantation of the continent catheterizable channel (CCC): native bladder or enterocystoplasty. METHODS.
- Conditions
- Neurogenic Bladder, Continent Cutaneous Urinary Diversion, Mitrofanoff
- Trial name
- ICODE (NCT04922437)
- Testing
- Native bladder implantation, Enterocystoplasty implantation
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Central Hospital, Nancy, France
Bladder Cancer Requiring Cystectomy, Ileal Conduit
A Feasibility Randomized Trial Evaluating Early vs Late Stent Removal Following Radical Cystectomy and Ileal Conduit Formation for Bladder Cancer
Bladder cancer is the 4th most common cancer in men and 5th most common type of cancer in Canada. Urothelial cancer accounts for approximately 90% of malignancies.
- Conditions
- Bladder Cancer Requiring Cystectomy, Ileal Conduit, Urinary Diversion
- Trial name
- STENT-OPT (NCT06595446)
- Testing
- Early Stent removal, Late Stent removal
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Western University, Canada
Muscle-Invasive Bladder Carcinoma, Muscle Invasive Bladder Urothelial Carcinoma
Study on the Quality of Life and Pathological State in Patients Who Underwent Radical Cystectomy
Observational study on the quality of life and pathological state of patients underwent radical cystectomy.
- Conditions
- Muscle-Invasive Bladder Carcinoma, Muscle Invasive Bladder Urothelial Carcinoma, Bladder Cancer TNM Staging, Bladder Cancer Stage IIa
- Trial name
- NCT06170177
- Testing
- Radical Cystectomy
- Where
- Italy
- Volunteers
- 4,000 people
- Sponsor
- IRCCS San Raffaele
Urinary Bladder Neoplasms
Study Comparing Open Radical Cystectomy With Robot-assisted Cystectomy in Patients With Bladder Cancer
The purpose of the study to compare two established methods of radical cystectomy (RC) in patients with bladder cancer. The participants will be treated under conditions in alignment with up-to-date guidelines and care.
- Trial name
- NCT03977831
- Testing
- Radical Cystectomy
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Parastomal Hernia
Prevention of Parastomal Hernia by Mesh Placement
Concurrent placement of a mesh during formation of ileal conduit will decrease the incidence of parastomal hernia and associated complications.
- Trial name
- NCT02404545
- Testing
- Ethicon Physiomesh
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Miami
Bladder Cancer
Multicentral Preventive Antibiotics With Cystectomy Within Enhanced Recovery After Surgery
The current usage of antibiotic prophylaxis (AP) in radical cystectomy (RC) is aimed to reducing the incidence of surgical site infections and incidence of unnecessary prescribing of antibiotics.
- Trial name
- MACS (NCT05392634)
- Testing
- Meropenem 1000 mg, Amoxicillin+clavulanic acid 1200 mg or Cefuroksim 1500mg
- Where
- Russia
- Volunteers
- 98 people
- Sponsor
- N.N. Petrov National Medical Research Center of Oncology
Bladder Cancer
MOdified Urinary Conduit to Lower Strictures After radIcal Cystectomy
Cystectomy is the chosen treatment of bladder cancer in 400 cases every year in DK. In replacement of the removed bladder, a urinary diversion is constructed using 15cm of terminal ilium (Ad Modum Bricker).
- Trial name
- MOSAIC (NCT04391790)
- Testing
- Cystectomy and modified urinary conduit, Cystectomy and standard urinary conduit ad modum Bricker
- Where
- 5 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- Jørgen Bjerggaard Jensen
Fluid Retention Tissue
Comparison of Liberal and Restrictive Fluid Management on the Endothelial Glycocalyx in Radical Cystectomy
The aim of this study is to compare the effect of the liberal and restrictive fluid treatments which are routinely performed in major urological surgeries in the perioperative period on ANP release and the endothelial glycocalyx…
- Trial name
- NCT04780490
- Testing
- liberal fluid management, restrictive fluid management
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Istanbul University
Bladder Cancer
Compare the Quality of Life Between Patients With Conduit Diversions or Orthotopic Neobladders
The aim of this study is to compare the health-related quality of life (HRQoL) between patients underwent conduit diversion and orthotopic neobladder after radical cystectomy.
- Trial name
- NCT02174185
- Testing
- validated health-related quality of life questionnaires
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Huazhong University of Science and Technology
Cancer, Bladder
Opioid Free Anesthesia in Prolonged Surgery
this study is designed to compare intrathecal bolus of bupivacaine-dexmedetomidine versus continuous epidural fentanyl infusion in providing effective operative analgesia, intraoperative hemodynamic stability and less…
- Trial name
- NCT05262166
- Testing
- INTRATHECAL dexmedetomidine INJECTION
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Mansoura University
Patient Satisfaction, Quality of Life
Patient Experiences Following Urinary Diversion as Part of Surgery for Advanced and Recurrent Rectal Cancer
The outcomes of patients who undergo radical surgery for locally advanced and recurrent rectal cancer have improved vastly, but there is a lack of emphasis on the quality-of-life outcomes of these patients.
- Conditions
- Patient Satisfaction, Quality of Life, Patient Participation
- Trial name
- Pelvex 3 (NCT04715308)
- Testing
- Urinary diversion
- Where
- Ireland
- Volunteers
- 1,200 people
- Sponsor
- St Vincent's University Hospital, Ireland
Muscle-Invasive Bladder Carcinoma, Radical Cystectomy
Prophylactic Antibiotics in Cystectomy With Diversion
Using a randomized 2 arm design, this study is being conducted to test for non-inferiority of no prophylactic antibiotic therapy versus the prophylactic oral antibiotic, nitrofurantoin, through comparison of rates of…
- Conditions
- Muscle-Invasive Bladder Carcinoma, Radical Cystectomy, Ileal Conduit, Neobladder Diversion
- Trial name
- NCT06190197
- Testing
- Prophylactic antibiotics postoperatively.
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Minnesota
Bladder Cancer, Patient Engagement
Recovery Support for Bladder Cancer Patients and Caregivers
For patients with certain types of bladder cancer, the removal of the bladder and the construction of an artificial bladder or reservoir are the only treatment options.
- Conditions
- Bladder Cancer, Patient Engagement, Patient Empowerment, Ileal Conduit
- Trial name
- NCT04055311
- Testing
- Cancer Resource Information Support (CRIS), Usual Care Enhanced
- Where
- 2 sites in United States
- Volunteers
- 174 people
- Sponsor
- Northwell Health
Bladder Cancer
Open Versus Robot Assisted Radical Cystectomy With Totally Intracorporeal Urinary Diversion.
This prospective randomized study is designed to provide high level of evidence supporting superiority of robot assisted (RA) versus open (O) radical cystectomy (RC).
- Trial name
- NCT03434132
- Testing
- Open or robotic radical cystectomy
- Where
- Italy
- Volunteers
- 116 people
- Sponsor
- Regina Elena Cancer Institute
Pain, Catheter Complications
Study Comparing Urinary Diversion (Transurethral/Suprapubic) After Radical Prostatectomy
The study aims to show the technical feasibility of the suprapubic urinary diversion after endoscopic extraperitoneal radical prostatectomy (EERPE) and has a greater comfort for the patients with at least the same catheter…
- Trial name
- NCT01465594
- Testing
- transurethral catheter after EERPE/ RALP, suprapubic catheter after EERPE /RALP
- Where
- Germany
- Volunteers
- 106 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Bladder Cancer
Perioperative Oral Nutrition Intervention for Patients Undergoing Radical Cystectomy
The current study is designed to assess the impact of an enriched oral nutritional shake (Ensure Plus®) to improve the nutritional status and patient outcome after surgery to remove a cancerous bladder (radical cystectomy).
- Trial name
- NCT02050451
- Testing
- Ensure Plus®, Multivitamin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vanderbilt University
Frail Elderly Syndrome, Bladder Disease
Perioperative Multimodal Care for Cystectomy Frail Patient
Major surgery in the elderly and frail patient is a challenge. Optimal perioperative management is essential for outcome and survival.
- Conditions
- Frail Elderly Syndrome, Bladder Disease, Nutrition Disorders, Cognitive Symptom
- Trial name
- NCT03065348
- Testing
- oral whey protein, Immunonutrition, Carbohydrate Drink
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Bladder Cancer, Muscle-Invasive Bladder Carcinoma
Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy
Subjects will be randomized into 2 groups (stent or no stent) prior to radical cystectomy with ileal conduit urinary diversion (RCIC). They will follow the standard of care and be enrolled in the study for 12 months post-op.
- Conditions
- Bladder Cancer, Muscle-Invasive Bladder Carcinoma, Urothelial Carcinoma, Pelvic Malignancy
- Trial name
- NCT07234968
- Testing
- Ureteral Stent Placement, No Ureteral Stent, Indocyanine Green with Fluorescence Imaging
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Thomas Jefferson University