Clinical trials: Ureteric Obstruction
Urolithiasis, Urologic Diseases
Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis
To investigate the effectiveness of percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease (with either infection and/or pain and/or…
- Conditions
- Urolithiasis, Urologic Diseases, Urinary Calculi, Urinary Obstruction
- Trial name
- STONE (NCT04594161)
- Testing
- Percutaneous Nephrostomy, Double J catheter
- Where
- Netherlands
- Volunteers
- 204 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Ureteral Obstruction
The RELIEF™ Ureteral Stent - Assessment of Retrograde Urinary Reflux and Distal Coil Bladder Position
Traditional ureteral stents are commonly used in renal and ureteral procedures, and their use is associated with many morbidities which can affect patients' quality of life.
- Trial name
- NCT03266770
- Testing
- RELIEF Stent
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University Hospitals Cleveland Medical Center
Ureteral Obstruction
Treatment of Symptoms After Stent Placement for Urinary Tract Obstruction
The purpose of this study is to determine whether combination therapy with Tolterodine ER and Tamsulosin is more effective than monotherapy with tamsulosin alone in reducing stent symptoms.
- Trial name
- NCT01741454
- Testing
- Tamsulosin, Tolterodine ER
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of Wisconsin, Madison
Ureteral Obstruction
Ureteral Reimplantation for the Treatment of Extrinsic Malignant Ureteral Obstruction
A single center single arm prospective study, assessing the outcome of ureteral re-implantation for malignant ureteral obstruction.
- Trial name
- NCT02160652
- Testing
- Laparoscopic ureteral re-implantation.
- Volunteers
- 50 people
- Sponsor
- Rabin Medical Center
Obstructive Uropathy, Hydronephrosis
Safety and Efficacy of Ultrasound-Guided Percutaneous Nephrostomy in Oncology Patients
Obstructive uropathy is a serious complication frequently seen in cancer patients, occurring when urine flow from the kidneys is blocked by tumor compression, invasion, or benign etiologies such as radiation-induced strictures…
- Conditions
- Obstructive Uropathy, Hydronephrosis, Ureteral Obstruction, Acute Kidney Injury
- Trial name
- NCT07855666
- Testing
- Ultrasound-guided percutaneous nephrostomy
- Volunteers
- 40 people
- Sponsor
- Assiut University
Hydronephrosis; Obstruction, Ureter, Renal Failure
Tandem Polyurethane Stents Compared to Single Silicone Stent for Malignant Ureteral Obstruction
Malignant ureteral obstruction (MUO) is an extrinsic ureteral obstruction caused by malignant diseases. This study aim to compare tandem 6 Fr Percuflex™ stents and single large-caliber 8Fr silicone stent in patients with MUO.
- Conditions
- Hydronephrosis; Obstruction, Ureter, Renal Failure, Malignancy, Ureter Obstruction
- Trial name
- TSTENT (NCT05992363)
- Testing
- ureteral stent\s insertion
- Where
- 2 sites in Israel
- Volunteers
- 106 people
- Sponsor
- Rabin Medical Center
Ureteral Obstruction
Room Air a Safe Alternative to Dye Injection in Ureterography
The procedure began in the Thirties .Retrograde pyelography is an essential step in most endoscopic procedure. This procedure is used as an investigation, with different indication in the past and the present, to delineate the…
- Trial name
- NCT06110299
- Testing
- air injection
- Volunteers
- 24 people
- Sponsor
- Assiut University
Renal Injury, Kidney Injury
Efficacy and Safety of Renalof® in the Removal of Calculi Smaller Than 10 mm Located in the Reno-Ureteral Tract
Given the high recurrence of urolithiasis in patients, the search for less aggressive and preventive treatments is increasingly necessary.
- Conditions
- Renal Injury, Kidney Injury, Kidney Calculi, Ureteral Obstruction
- Trial name
- NCT04695951
- Testing
- Renalof
- Where
- Nicaragua
- Volunteers
- 155 people
- Sponsor
- Catalysis SL
Ureterohydronephrosis, Ureter Obstruction
Robot-Assisted Pyeloplasty in Young Children
The goal of this retrospective study is to analyse the outcomes of Robot-Assisted Pyeloplasty in participants younger than 5 years old: indication criteria clinical symptoms operating time length of stay complications follow-up
- Conditions
- Ureterohydronephrosis, Ureter Obstruction, Child, Only
- Trial name
- PYEROB (NCT06734455)
- Testing
- Robot-Assisted Pyeloplasty
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Destinval Christelle
Ureteral Obstruction
Tolerance and Effectiveness of Ureteral Stents MEMOKATH ® 051 in Chronic Strictures of the Ureter
TOTEME offers to treat certain chronic strictures of the ureter with MEMOKATH 051 to assess its effectiveness, tolerance and mean durability during a 3 years follow up period.
- Trial name
- TOTEME (NCT00790686)
- Testing
- Insertion of Memokath 051
- Where
- 4 sites in France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Bordeaux
Ureter Obstruction
Primary Versus Deferred Ureteroscopy for Calculus Anuria in Children
To evaluate the role of both primary and deferred URS in the management of calculus anuria concerning the feasibility, clinical outcome, and cost-effectiveness in children in a comparative study
- Trial name
- NCT04980079
- Testing
- Primary ureterscopy URS, deferred ureteroscopy URS
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Valley University
Ureteral Obstruction, Stricture Ureter
Use of SPY Fluorescent Angiography to Reduce Ureteroenteric Stricture Rate Following Urinary Diversion
Ureteroenteric anastomotic stricture is a well-known complication of urinary diversion which occurs in 4-25% of patients. Recent study has yielded that radiation is a significant risk factor for development of ureteroenteric…
- Trial name
- NCT05022199
- Testing
- SPY fluorescent angiography
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
Urinary Stone, Renal Colic
Radiomics and Image Segmentation of Urinary Stones by Artificial Intelligence
Kidney stone disease causes significant morbidity, and stones obstructing the ureter can have serious consequences. Imaging diagnostics with computed tomography (CT) are crucial for diagnosis, treatment selection, and follow-up.
- Conditions
- Urinary Stone, Renal Colic, Obstruction Ureter, Urosepsis
- Trial name
- RISUS_AI (NCT06412900)
- Where
- Norway
- Volunteers
- 522 people
- Sponsor
- Oslo University Hospital
Urolithiasis
Multi-Center Comparison of Dual Lumen Versus Single Lumen Ureteroscopes
Urolithiasis (kidney stones) is a common disease process affecting people all across the world. Usually, if the stone size is small, it is able to pass through the urinary system and exit the bladder on its own with no treatment.
- Trial name
- NCT02123082
- Testing
- Storz single Lumen Ureteroscope, Dual Lumen Ureteroscope
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Ureteral Stricture, Ureteral Obstruction
An Integrated Multi-omics Study on the Molecular Mechanisms of Ureteral Stricture
The goal of this observational study is to investigate the systemic pathogenesis and identify potential diagnostic biomarkers in patients with ureteral stricture and healthy volunteers.
- Conditions
- Ureteral Stricture, Ureteral Obstruction, Microbiome, Metabolomics
- Trial name
- US-MOP (NCT07409870)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Ureteral Obstruction
Laparoscopic Pyeloplasty Registry and Database
The gold standard for the treatment of ureteropelvic junction obstruction (UPJO) is the open pyeloplasty. As a minimally invasive alternative, many centers are currently offering laparoscopic pyeloplasty (LP) as primary therapy…
- Trial name
- NCT00169650
- Testing
- Registry and database
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Indiana Kidney Stone Institute
Cancer, Urinary Obstruction
Obstruction of Malignancy: Percutaneous Renal vs Endoscopic Stent
This research study will compare two procedures commonly used to treat urinary obstruction due to cancer. Sometimes cancer blocks one or both ureters (narrow tubes in the body that carry urine from the kidneys to the bladder).
- Conditions
- Cancer, Urinary Obstruction, Malignancy, Urinary Dysfunction
- Trial name
- NCT05640115
- Testing
- Ureteral Stent, Percutaneous Nephrostomy Tube Placement
- Where
- United States
- Sponsor
- University of Chicago
Renal Calculi, Ureteral Obstruction
Assessment of Drug-eluting Ureteral Stent on Bacterial Adherence and Biofilm Formation
The purpose of this study is to determine the clinical effects of a triclosan stent on adherent bacteria, stent biofilms, and patient urine cultures in patients with an indwelling triclosan ureteral stent.
- Trial name
- NCT00250406
- Testing
- Ureteral Stent
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Ureteral Obstruction
Functional MR Urography
The objective of functional Uro MR is to add to an initial morphological phase, based on T2 and T1 weighted MR sequences, a sequential contrast-enhanced acquisition allowing to obtain functional semi-quantitative parameters from…
- Trial name
- NCT00301470
- Testing
- MR urography
- Where
- 16 sites in France
- Volunteers
- 550 people
- Sponsor
- Central Hospital, Nancy, France
Open, Laparoscopic
Open Versus Laparoscopic Dismembered Pyeloplasty Among Adult Patients With Primary Pelvi-Ureteric Junction Obstruction
To prospectively compare the perioperative, morphological and functional outcomes on short and medium term between laparoscopic (LP) and open pyeloplasty (OP) patients.
- Conditions
- Open, Laparoscopic, Dismembered Pyeloplasty, Primary Pelvi-Ureteric Junction
- Trial name
- NCT06572371
- Testing
- Laparoscopic pyeloplasty, Open pyeloplasty
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Tanta University