Clinical trials: Ureteral Stones, Kidney Stones
Kidney Calculi, Ureteral Calculi
Impact of Humid-Heat on Gut-Tryptophan-Stone Pathway
Investigating the differences in gut microbiota composition and tryptophan metabolite levels between kidney stone patients and healthy individuals, with special focus on: 1.
- Trial name
- NCT07043374
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Urolithiasis, Kidney Stones
Pain Control During ESWL Using Non-Opioid Analgesics
This prospective randomized controlled trial aims to compare the analgesic efficacy of three non-opioid analgesics (ibuprofen, paracetamol, and tenoxicam) during extracorporeal shock wave lithotripsy (ESWL).
- Conditions
- Urolithiasis, Kidney Stones, Ureteral Stones
- Trial name
- ESWL-PAIN (NCT07512297)
- Testing
- Ibuprofen (Brufen®), Paracetamol (drug), Tenoxicam
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- University of Gaziantep
Renal Calculi
Using Retrograde Intrarenal Surgery for Managing Staghorn Renal Stones.
This prospective, randomized study is comparing the safety and efficacy of using two types of ureteral access sheaths in managing staghorn renal stones by retrograde intrarenal surgery.
- Trial name
- NCT07342361
- Testing
- Retrograde intrarenal surgery
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Helwan University
Renal Stone, Retrograde Intrarenal Surgery
Tamsulosin Assisted Ureteral Access Sheath Insertion
Aim is to study if 1 week of pre operative tamsulosin would enable easier insertion of ureteral access sheath in primary retrograde intrarenal surgery for renal stone disease
- Conditions
- Renal Stone, Retrograde Intrarenal Surgery, Urolithiasis
- Trial name
- NCT05197088
- Testing
- Tamsulosin
- Where
- Singapore
- Volunteers
- 110 people
- Sponsor
- Sengkang General Hospital
Urolithiasis, Kidney Calculi
Safety and Efficacy of Traditional Versus Flexible and Navigable Suction Sheath in Retrograde Intra-Renal Stone Surgery
This study compares two techniques used during RIRS for the treatment of kidney stones measuring up to 20 mm. During RIRS, surgeons often use a device called a UAS to help pass instruments into the urinary system and to assist…
- Conditions
- Urolithiasis, Kidney Calculi, Nephrolithiasis
- Trial name
- NCT07286071
- Testing
- Retrograde intrarenal surgery using a ureteral access sheath with suction, Retrograde intrarenal surgery using a traditional ureteral access sheath
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Urolithiasis
Assessment of Urinary Microplastic Concentration in Patients With Urolithiasis: A Prospective Case-Control Study
This prospective observational case-control study aims to evaluate the presence and burden of microplastic particles in urine samples from patients with kidney and ureteral stones and to compare these findings with healthy…
- Trial name
- Microplastics (NCT07841834)
- Testing
- No Intervention
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Renal Colic
The Efficacy of Alpha-blockers for Expulsion of Distal Ureteral Stones
Most of the patients suffering from renal colic have a distal ureterolithiasis. It had been demonstrated that α adrenoreceptors antagonists, given to patients suffering from renal colic, due to distal ureterolithiasis, had…
- Trial name
- NCT00451061
- Testing
- Alfuzosin, Tamsulosin
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Soroka University Medical Center
Kidney Stone, Retrograde Intrarenal Surgery (RIRS)
MIRABEGRON AND UAS OUTCOMES DURING RIRS
The aim of this study is to evaluate whether there is a difference in the passage rate of the ureteral access sheath between patients who used mirabegron (a beta-3 receptor agonist) for overactive bladder and those who underwent…
- Conditions
- Kidney Stone, Retrograde Intrarenal Surgery (RIRS), Ureteral Access Sheath
- Trial name
- NCT07566416
- Testing
- Retrograde intrarenal surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 131 people
- Sponsor
- Ankara Training and Research Hospital
Renal Calculi
FANS vs Standard Ureteral Access Sheath in fURS
This is a prospective, interventional single blinded, randomized, single-center study designed to compare the efficacy of a ureteral access sheath with integrated suction (FANS) versus a standard ureteral access sheath (UAS) in…
- Trial name
- CLEAR-URS (NCT07463157)
- Testing
- Standard ureteral access sheath, Flexible and Navigable Suction (FANS) Ureteral Access Sheath
- Where
- Italy
- Volunteers
- 134 people
- Sponsor
- IRCCS San Raffaele
Urolithiasis, UTI
Antibiotic Prophylaxis With Routine Ureteral Stent Removal
This study will be a single-institutional randomized, single-blinded prospectively controlled clinical trial of a single dose of Ciprofloxicin 500mg antibiotic tablet as prophylaxis at the time of office flexible cystoscopy with…
- Trial name
- STENTABX (NCT02944825)
- Testing
- Ciprofloxacin, trimethoprim/sulfamethoxazole, No Intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, San Diego
Kidney Calculi, Urolithiasis
Antibiotic Irrigation and Suction Ureteral Access Sheath in RIRS
Retrograde intrarenal surgery (RIRS) is a widely used treatment for kidney stones; however, postoperative infectious complications remain a significant concern.
- Conditions
- Kidney Calculi, Urolithiasis, Urinary Tract Infections
- Trial name
- NCT07655050
- Testing
- Standard Retrograde Intrarenal Surgery, Gentamicin Irrigation, Suction-Enabled Ureteral Access Sheath
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Hitit University
Renal Stone, Ureteral Stone
Better Lithotripsy and Ureteroscopy Evaluation of Stenting (BLUES)
This multi-center trial is being completed to compare patient outcomes related to the Imajin silicone stent in comparison to non-silicone polyurethane stents after ureteroscopy.
- Trial name
- BLUES (NCT05026710)
- Testing
- Silicone (Coloplast Imajin Hydro) ureteral stent, Non-silicone (Polyurethane/Percuflex) ureteral stent (any manufacturer)
- Where
- 10 sites in United States
- Volunteers
- 224 people
- Sponsor
- University of Michigan
Kidney Stones, Ureteral Stones
The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients
To determine if emergency department patients with acute ureteral colic pain due to a ureteral stone who are treated with tamsulosin, versus placebo, will experience a shorter time to passage of their stone or resolution of their…
- Trial name
- NCT00448123
- Testing
- Tamsulosin
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Robert Swor
Nephrolithiasis, Kidney Stone
ClearPetra™ Vacuum-assisted Ureteral Access Sheath vs Traditional Approach
Ureteroscopy has been considered the best approach when treating renal stones smaller than 2 cm. This procedure is usually performed together with ureteral access sheaths, which helps protect the ureter mucosa and lowers…
- Trial name
- VA-UAS vs trad (NCT06547632)
- Testing
- ClearPetra Ureteral access sheath
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Ureteral Calculi, Renal Calculi
Intraureteral Lidocaine for Post-Ureteroscopy Pain
Ureteroscopy (URS) is minimally invasive procedure for management of renal stones. URS is often involves concomitant of an indwelling ureteral stents.
- Trial name
- NCT01450566
- Testing
- Lidocaine, Saline
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Queen's University
Stone Ureter
Extra-Corporeal Shock Wave Lithotripsy for Renal and Upper Ureteral Stones in Adults Under Locally Infiltrate d Anaesthetics ; a Clinical Randomized Controlled Study
There are many treatment modalities available for managing renal and upper ureteric stones. They range from completely non-invasive outpatient procedures to invasive procedures requiring hospital admission and increased risks of…
- Trial name
- NCT06462573
- Testing
- locally infilterating anaethesia like lidocaine, general anaethesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Kidney Stone, Ureteral Stone
High Powered Stone Dusting vs. Fragmentation and Basketing at Time of Ureteroscopy
The purpose of this study is to determine the differences in stone free results, patient side effects, and patient satisfaction between dusting vs.
- Trial name
- NCT05006937
- Testing
- Dusting, Basket extraction
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Northwestern University
Kidney Stones
Alfuzosin for Medical Expulsion Therapy of Ureteral Stones
The goal of this study is to conduct a prospective controlled trail of four currently approved Department of Defense (DOD) - formulary medications for use as medical expulsion therapy (MET) for kidney stones.
- Trial name
- MET (NCT00713739)
- Testing
- Alfuzosin, nifedipine, doxazosin
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Kidney Calculi, Nephrolithiasis
Comparison of Suction and Conventional Ureteral Access Sheaths in Kidney Stone Surgery
The goal of this observational study is to compare conventional and suction (aspiration) ureteral access sheaths used during retrograde intrarenal surgery (RIRS) in adults with kidney stones.
- Trial name
- NCT07866209
- Testing
- Conventional Ureteral Access Sheath, Suction Ureteral Access Sheath
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Antalya Health Sciences University
Renal Stone, Ureteral Stone
Effectiveness of Holmium and Thulium Lasers With Ureteroscopy for Urinary Lithiasis
Holmium laser is the current gold standard for lithotripsy on urinary lithiasis, while Thulium is brand new. The latter has been released in July 2020 in Europe, and only in-vitro studies have been published.
- Trial name
- LiThuHol (NCT04871984)
- Testing
- Ureteroscopy for upper tract stone treatment with Holmium laser, Ureteroscopy for upper tract stone treatment with Thulium laser
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers