Clinical trials: Upper Endoscopy
Capsule Endoscopy
The Second-Generation MCCG for Upper Gastrointestinal Tract.
The aim of this study is to evaluate the clinical application of the second-generation MCCG with higher image resolution and frame rate for upper gastrointestinal tract compared with the first-generation.
- Trial name
- NCT03977935
- Testing
- the second-generation MCCG
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Severe Obesity, Hypoxia
Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures
The study evaluated the effect of non-invasive positive pressure ventilation (NIPPV) to decrease the incidence of desaturation events in patients with severe obesity undergoing upper endoscopy.
- Trial name
- NCT03529461
- Testing
- Non-invasive positive pressure ventilation through nasal mask, Rescue non-invasive positive pressure ventilation through nasal mask, Secondary rescue maneuvers
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bristol Hospital
Gastroscopy
Effect of Bispectral Index Monitoring (BIS) on Body Movement of Outpatients Undergoing Gastroscopy
Patients who meet the enrollment criteria were randomized 1:1 to either the BIS group or the OAA/S group. In the BIS group, the anesthesiologist set the target controlled infusion（TCI）parameters according to the patient's height…
- Trial name
- BIS (NCT05773807)
- Testing
- Bispectral index, Observer's assessment alert Sedation, Gastroscopy
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Gastric Lesion, Gastritis
Capsule Gastric Endoscopy for Gastric Disease Screening in Simulated Home Scenarios
The goal of this clinical trial is to evaluate the diagnostic accuracy of the AI-integrated Capsule Gastroscopy (ACG) system in simulated home-use conditions for detecting upper gastrointestinal (UGI) abnormalities.
- Conditions
- Gastric Lesion, Gastritis, Upper Gastrointestinal Bleeding (UGIB), Gastric Dysplasia
- Trial name
- NCT06848400
- Testing
- AI-integrated Capsule Gastroscopy (ACG) examination, Electronic gastroduodenoscopy (EGD) examination
- Where
- 12 sites in China, Hong Kong and 1 more
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
EGDS Preparation; Fasting; Lumevis
Implementation of Upper Gi Endoscopy Preparation: Fasting Versus Lumevis
One of the major problems for the endoscopist during esophagogastroduodenoscopy (EGDS) is the presence of foam, bubbles, mucus and saliva, whether small or large, which can compromise correct endoscopic visibility.
- Trial name
- NCT05401383
- Testing
- Lumevis (IIa class)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Azienda USL Modena
Obesity
Balanced Propofol Sedation During Upper Endoscopy in Morbidly Obese Patients
The purpose of this study is to evaluate the safety of propofol-based, gastroenterologist-administered sedation in severely obese patients (BMI≥35) undergoing upper endoscopy.
- Trial name
- NCT00782873
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Research Associates of New York, LLP
Obesity
A Prospective Study Evaluating The Utility of Transnasal Endoscopy With Roux en Y Gastric Bypass
Improvements in imaging technology have allowed for the development of small endoscopes ("slim scopes") half the size of a typical endoscope.
- Trial name
- NCT01526772
- Testing
- Endoscopy
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Upper Gastrointestinal Endoscopy
Sedation for Upper Gastrointestinal Endoscopy in Pediatric Patients
The purpose of this study is to compere between Propofol-Ketamine combination and Dexmedetomidine-Ketamine combination for sedation in upper gastrointestinal endoscopy in paediatric patients.
- Trial name
- NCT02863861
- Testing
- Dexmedetomidine-ketamine, propofol-ketamine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Obstructive Sleep Apnea
Mechanisms of Upper Airway Obstruction
The current study is designed to examine underlying mechanisms of action of lingual muscles in the maintenance of airway patency during sleep.
- Trial name
- DISE-CAD (NCT04322097)
- Testing
- Hypoglossal Nerve Stimulation
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Upper Gastrointestinal Bleeding (UGIB), Emergency Department Patient
A New Risk Score for the Emergency Department in Patients With Upper Gastrointestinal Bleeding
Abstract Background: The aim of this study was to develop a simpler, more practical, and highly effective risk scoring system for patients presenting to the emergency department with upper gastrointestinal bleeding.
- Conditions
- Upper Gastrointestinal Bleeding (UGIB), Emergency Department Patient, Risk Scores
- Trial name
- NCT06878183
- Testing
- Routine laboratory tests of the patients were examined (such as hemogram, biochemistry, bleeding parameters).
- Where
- Turkey (Türkiye)
- Volunteers
- 589 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Esophagogastroduodenoscopy, Simethicone
Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy
The goal of this randomized, double-blind, placebo-controlled clinical trial is to assess whether the combination of N-acetylcysteine and simethicone improves mucosal visibility during upper gastrointestinal endoscopy in adults…
- Conditions
- Esophagogastroduodenoscopy, Simethicone, N-Acetylcysteine, Premedication
- Trial name
- NACSIMET (NCT07245095)
- Testing
- Premedication with n-acetylcysteine, Premedication with simethicone
- Where
- 2 sites in Mexico
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hospital General de Mexicali
Upper Gastrointestinal Bleeding
Capsule Endoscopy for HEmorrhage in the ER
This is a multi-center randomized controlled trial examining the use of Video Capsule Endoscopy (VCE) to discharge low-moderate risk patients with suspected upper gastrointestinal bleeds (UGIB) from the Emergency Department (ED.)…
- Trial name
- CHEER (NCT03458000)
- Testing
- PillCam UGI, Standard of Care
- Where
- 3 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- George Washington University
Gastrointestinal Disease
Feasibility of Remote MCE for Upper GI Tract Examination Under Five-generation Network
With the combination of robotic and 5G network communication technology, telemedicine becomes more and more feasible and efficient.
- Trial name
- NCT04670692
- Testing
- 5G-MCE examination, MCE examination
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Gastrointestinal Diseases
Propofol Versus Midazolam in Sedation for Upper and Lower Gastrointestinal Endoscopy.
There has been rapid growth in the number and complexity of gastrointestinal (GI) endoscopic procedures performed during the last decade.
- Trial name
- NCT06358131
- Testing
- Endoscopy
- Where
- 2 sites in Egypt
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pain, Anxiety
The Effect of Virtual Reality Glasses During Endoscopy
Upper gastrointestinal endoscopy is an invasive procedure used to diagnose and treat pathologies in the gastrointestinal mucosa.
- Conditions
- Pain, Anxiety, Gastro-Intestinal Disorder
- Trial name
- NCT06718504
- Testing
- Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Gastrointestinal Endoscopy
Moderate Sedation Combined With Acupuncture Anesthesia in Gastroscopy and Colonoscopy on Screening Research
The purpose of this study is mainly about the feasibility and rationality of moderate sedation combined with acupuncture anesthesia in the application of gastroscopy and colonoscopy ,Then we evaluate the effectiveness and…
- Trial name
- NCT05485064
- Testing
- fentanyl, eletroacupuncture(transcutaneous electrical acupuncture point stimulation ), remimazolam
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Qingdao University
Bronchoscopy, Obstructive Sleep Apnea
Upper Airway Collapsibility Evaluation in Different Sedative Levels by Sleep Endoscopy
The purpose of this study is to evaluate the upper airway collapsibility by sleep endoscopy in different sedative levels. Propofol pump infusion will be used to achieve conscious sedation.
- Conditions
- Bronchoscopy, Obstructive Sleep Apnea, Conscious Sedation
- Trial name
- NCT01100554
- Testing
- Sleep endoscopy
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Droplet Spread, Covid19
COVID-19 Aerosol in EGD Using a Droplet Reduction Mouthpiece
Measurement of aerosolisation during esophagogastroduodenoscopy (EGD) to compare two types of mouthpieces, conventional versus a new and commercially available one 'the droplet reduction mouthpiece B1'.
- Trial name
- NCT04864015
- Testing
- Mouthpiece B1(Mouthpiece MPC-ST GMDN:62534 Generic name: Endoscopic bite block, basic, reusable
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Breath Exercise, State Anxiety
The Effect of Diaphragmatic Breathing Exercises Before Gastroscopy on Anxiety, Fear, and Vital Signs
Gastroscopy, performed as an invasive procedure for the diagnosis and treatment of upper gastrointestinal tract diseases, is often perceived by patients as an unpleasant and frightening experience, leading to anxiety (Hua et al.…
- Conditions
- Breath Exercise, State Anxiety, Adult Patients, Vital Signs Monitoring
- Trial name
- NCT07781943
- Testing
- Diaphragmatic Breathing Exercises
- Where
- Cyprus
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Stomach Diseases, Small Intestine Disease
Magnetically Controlled Capsule Endoscopy in Visualization of the UGI and Small Intestine
In this study, we retrospectively analyzed the videos of combined upper digestive tract and small intestine examination under MCE, so as to clarify the feasibility and diagnostic efficacy of MCE in one-time examination of the…
- Trial name
- NCT05069233
- Testing
- UGI+SB
- Where
- China
- Volunteers
- 593 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital