Clinical trials: Unilateral Inguinal Hernia Surgery
Inguinal Hernia Unilateral, Postoperative Pain Management
Transversalis Fascia Plane Block Versus Surgical Wound Infiltration for Postoperative Analgesia in Open Inguinal Hernia Repair
The purpose of this clinical trial is to evaluate whether two different analgesic techniques - ultrasound-guided Transversalis Fascia Plane Block (TFPB) and surgical wound infiltration - can improve postoperative pain control in…
- Conditions
- Inguinal Hernia Unilateral, Postoperative Pain Management, Regional Anaesthesia, Transversalis Fascia Plane Block
- Trial name
- TFPB-WIN (NCT07238829)
- Testing
- Ultrasound-Guided Transversalis Fascia Plane Block (TFPB), Surgical Wound Infiltration
- Volunteers
- 104 people
- Sponsor
- Ondokuz Mayıs University
Postoperative Pain
Phase 2 Herniorrhaphy Study for Opioid Elimination
This is a Phase 2, open-label study in subjects undergoing unilateral open inguinal herniorrhaphy.
- Trial name
- NCT03695367
- Testing
- HTX-011, Luer lock applicator, Vial access device
- Where
- 5 sites in United States
- Volunteers
- 63 people
- Sponsor
- Heron Therapeutics
Anesthesia, Spinal, Ambulatory Surgical Procedures
Spinal Anesthesia for Outpatient Abdominal Wall Surgery: Comparison of Bupivacaine, 2-chloroprocaine and Prilocaine
Considering fast-track principles, an ideal spinal anesthetic should have minimal complications and above all fast recovery so reducing in-hospital stay.
- Conditions
- Anesthesia, Spinal, Ambulatory Surgical Procedures, Hernia, Inguinal, Hernia, Umbilical
- Trial name
- spinal (NCT02813382)
- Testing
- Bupivacaine, Prilocaine, Chloroprocaine
- Volunteers
- 101 people
- Sponsor
- AZ St.-Dimpna Geel
Inguinal Hernia Unilateral
Laparoscopic Transabdominal Preperitoneal Surgical Repair of Inguinal Hernia Using Sutured Repair Versus Tacker Use
Background: Mesh fixation is a critical step in laparoscopic Transabdominal Preperitoneal (TAPP) hernia repair because fixation is a significant step to prevent the hazard of mesh migration, but is supposed to be associated with…
- Trial name
- NCT05574751
- Testing
- Titanium tacker, Polypropylene 0
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
Hernia, Inguinal, Hydrocele
The Addition of Clonidine to 0.2% Ropivacaine for Wound Instillation After Minor Lower Abdominal Surgery in Children
The current study will compare the effects on postoperative pain relief of "freezing" (ropivacaine 0.2 %) alone and in combination with clonidine for a nerve block in children undergoing hernia repair.
- Trial name
- NCT00130091
- Testing
- clonidine
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Eastern Ontario
Inguinal Hernia
Hernia Exploration oR Not In Infants Analysis
This study evaluates the effectiveness and cost-effectiveness of contralateral surgical exploration during unilateral inguinal hernia repair in children younger than six months with a unilateral inguinal hernia.
- Trial name
- HERNIIA (NCT03623893)
- Testing
- Contralateral exploration
- Where
- 7 sites in Netherlands
- Volunteers
- 416 people
- Sponsor
- Amsterdam UMC, location VUmc
Inguinal Hernia Unilateral, Complications of Surgical Procedures or Medical Care
Desarda Tissue Technique vs Lichtenstein Technique for Primary Inguinal Hernia Repair
This study aims to evaluate whether a surgical technique (Desarda) is superior to the commonly used surgical technique (Lichtenstein) in inguinal hernia repair concerning the occurrence of postoperative complications.
- Trial name
- HP-tis (NCT06650878)
- Testing
- Desarda, Lichtenstein
- Where
- Spain
- Volunteers
- 478 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Postoperative Pain
Analgesic Efficacy of Sequential Rapid Versus Slow Intrathecal Injection Of Dexmedetomidine Followed by of Hyperbaric Bupivacaine in Inguinal Hernia Repair Surgery
Analgesic Efficacy of Sequential Rapid Intrathecal Injection Of Dexmedetomidine Followed by Slow Injection of Hyperbaric Bupivacaine Versus Sequential Slow Injection of Both Drugs in Patients Undergoing Unilateral Inguinal Hernia…
- Trial name
- NCT06253260
- Testing
- Analgesic Efficacy of Sequential Rapid Intrathecal Injection Of Dexmedetomidine Followed by Slow Injection of Hyperbaric Bupivacaine Injection in Patients Undergoing Unilateral Inguinal Hernia Repair, Analgesic Efficacy of Sequential Slow Intrathecal Injection Of Dexmedetomidine Followed by Slow Injection of Hyperbaric Bupivacaine in Patients Undergoing Unilateral Inguinal Hernia Repair Surgery
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Primary Unilateral Inguinal Hernia
SIngle Port vs Standard TEP for Primary Inguinal Hernia Repair
This study is carried out to determine if laparoscopic inguinal TEP repair of the hernia using a mesh carried out with only 1 port (hole) results in the reduction of post- operative pain and use of painkillers, shorter hospital…
- Trial name
- LESSTEP (NCT02302937)
- Testing
- Group A will undergo laparoscopic TEP inguinal hernia repair with 3 ports (10 mm , and 2 ports of 5 mm ), Group B will undergo laparoscopic TEP inguinal hernia repair with a single port
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- National University Hospital, Singapore
Inguinal Hernia Unilateral, Erector Spinae Plane Block
Effect of Preoperative Erector Spinae Plane Block on Recovery Quality, Time to Return to Daily Activities, and Postoperative Pain Scores in Inguinal Hernia Surgery
This study aims to evaluate the effect of the erector spinae plane block (ESPB), performed after surgery, on quality of recovery, postoperative pain, and time to return to daily activities in patients undergoing open inguinal…
- Conditions
- Inguinal Hernia Unilateral, Erector Spinae Plane Block, Quality of Recovery (QoR-15), Numeric Rating Scale
- Trial name
- ESPB for IHR (NCT07509957)
- Testing
- Erector Spinae Plane Block (ESPB) group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanliurfa Education and Research Hospital
Postoperative Pain
Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)
This is a Phase 3, randomized, double-blind, saline placebo- and active-controlled, multicenter study to evaluate the analgesic efficacy and safety of HTX 011 administered via local administration into the surgical site in…
- Trial name
- NCT03237481
- Testing
- HTX-011, Bupivacaine HCl, Luer-lock applicator
- Where
- 24 sites in United States, Belgium
- Volunteers
- 418 people
- Sponsor
- Heron Therapeutics
Inguinal Hernia Unilateral, Postoperative Wound Inflammation
Postoperative Ozonated Oil Dressing After Open Inguinal Hernia Repair: A Randomized Pilot Trial
This study looks at whether a special wound dressing containing ozonated oil can reduce early wound inflammation after open inguinal hernia surgery.
- Trial name
- OZONE-HERNIA (NCT07328698)
- Testing
- ozonated oil, Standard Sterile Dressing
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Nigde Omer Halisdemir University
Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery
Preemptive IV Ibuprofen for Neurocognitive Recovery and Analgesic Needs After Inguinal Hernia Surgery
The primary objective of this study is to evaluate the effects of preemptive intravenous ibuprofen administration on delayed neurocognitive recovery (dNCR), postoperative pain management, and the overall quality of recovery in…
- Conditions
- Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery, Postoperative Pain, Neuroinflammation
- Trial name
- IBU-COG (NCT07424001)
- Testing
- Ibuprofen (400 mg x 4)
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Mehmet Çiğdem
Inguinal Hernia, Primary
The Outcome After Lichtenstein Operation vs. ProGrip Patch Repair of Inguinal Hernia
For the present study, 400 consecutive men with unilateral primary inguinal hernia are randomized to Lichtenstein repair using either light weight polypropylene mesh (38g/m2) or light weight ProGrip mesh.
- Conditions
- Inguinal Hernia, Primary, Unilateral
- Trial name
- NCT01026935
- Testing
- Open inguinal hernia repair
- Where
- 2 sites in Finland
- Volunteers
- 398 people
- Sponsor
- Helsinki University Central Hospital
Pain, Postoperative
Intrathecal Non-preservative-free Morphine With Bupivacaine Versus Intrathecal Bupivacaine Alone for Analgesia in Unilateral Inguinal Hernia Repair Surgeries
This study will evaluate the efficacy and safety of intrathecal non-preservative-free morphine and its effect on pain in patients undergoing unilateral inguinal hernia surgeries.
- Trial name
- NCT06319859
- Testing
- Morphine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Transversus Abdominis Plane Block
The Efficacy of Different Bupivacaine Concentrations in Pediatric Patients Undergoing Transversus Abdominis Plane Block
This study is designed to compare the analgesic efficacy of different bupivacaine concentrations in pediatric patients undergoing ultrasound-guided transversus abdominis plane (TAP) block for unilateral inguinal hernia repair.
- Trial name
- NCT04202367
- Testing
- 1 mg.kg-1 bupivacaine 0.25%, 1 mg.kg-1 bupivacaine 0.125%
- Volunteers
- 74 people
- Sponsor
- Istanbul University
Laparoscopic Surgery, Herniorrhaphy
Comparison the Analgesic Efficacy of Ultrasonographic Bilateral TAP and Anesthetic Infiltration Into the Surgery Field for Laparoscopic Unilateral TEP Herniorrhaphy
Laparoscopic inguinal hernia repair is a common surgical procedure, but postoperative pain management remains a challenge. This prospective, randomized study aims to compare the analgesic efficacy of preperitoneal and surgical…
- Conditions
- Laparoscopic Surgery, Herniorrhaphy, Inguinal Hernia Unilateral, Transversus Abdominis Plane (TAP) Block
- Trial name
- NCT06894420
- Testing
- Surgeon-Initiated Local Anesthetic, Transversus abdominis plane (TAP) block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Primary Unilateral Inguinal Hernias
Validation of Quality of Life Assessment After Laparoscopic TAPP and TEP Surgery of Inguinal Hernias Using EuraHS of Life Score and Carolinas Comfort Scale™
A multicenter observational study trial validating Quality of Life assessment using EuraHS Quality of Life score and Carolinas Comfort scale™ in patients before and after laparoscopic unilateral inguinal hernia repair.
- Trial name
- LIQUOR (NCT01936584)
- Testing
- TAPP repair for inguinal hernias, TEP repair for inguinal hernia, EuraHS-QoL questionnaire
- Where
- 3 sites in Belgium
- Volunteers
- 101 people
- Sponsor
- University Hospital, Ghent
Analgesia
Study of Post-Herniorrhaphy Non-opioid MMA Regimens
This is a Phase 3b, open-label study to assess postoperative opioid use in subjects undergoing unilateral open inguinal herniorrhaphy with intraoperative administration of HTX-011 and a postoperative non-opioid multimodal…
- Trial name
- NCT03907176
- Testing
- HTX-011, Luer lock applicator, Ibuprofen
- Where
- 30 sites in United States
- Volunteers
- 209 people
- Sponsor
- Heron Therapeutics
Hernia Inguinal, Pain Postoperative
Predictive Factors for the Effectiveness of the Ilioinguinal Iliohypogastric Nerve Block for Hernia Surgery
Inguinal hernia repair is a common surgical procedure done as day surgery. Because patients need to be discharged on the same day, the choice of anesthesia technique is influenced.
- Conditions
- Hernia Inguinal, Pain Postoperative, Regional Anesthesia
- Trial name
- VALI (NCT06121726)
- Testing
- Ilioinguinal-Iliohypogastric nerve block, Local anesthetic
- Where
- Italy
- Volunteers
- 343 people
- Sponsor
- University of Padova