Clinical trials: Undergoing Deep Brain Stimulation (DBS) Surgery
Parkinson's Disease
A Study to Evaluate Feasibility, Safety, and Clinical Responses of Implanting Autologous Peripheral Nerve Tissue Into the Brain for Non-motor or Motor Symptoms in Patients With Parkinson's Disease Undergoing DBS Surgery
The investigators propose a Phase I single surgical-center, double-blinded randomized parallel clinical trial involving bilateral autologous peripheral nerve tissue (PNT) delivery into the NBM or the alternate target also…
- Trial name
- STAR (NCT06683378)
- Testing
- Reparative Autologous peripheral nerve tissue
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Craig van Horne, MD, PhD
Treatment Resistant Depression, Undergoing Deep Brain Stimulation (DBS) Surgery
Tractography Guided Subcallosal Cingulate Deep Brain Stimulation for Treatment Resistant Depression
Treatment resistant depression remains a major problem for individuals and society. Surgical procedures may provide relief for some of these patients.
- Trial name
- NCT03952962
- Testing
- Abbott Laboratories Infinity™ implantable deep brain stimulation system
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Nader Pouratian
Parkinson Disease, Deep Brain Stimulation
Effect of Mediterranean Diet on Nutrition in Parkinson's Disease Patients With Bilateral Subthalamic Deep Brain Stimulation
The goal of this clinical trial is to evaluate whether Mediterranean diet can help manage body weight and improve body composition in adult Parkinson's disease patients who have undergone bilateral subthalamic nucleus deep brain…
- Conditions
- Parkinson Disease, Deep Brain Stimulation, Deep Brain Stimulation Surgery
- Trial name
- NCT07187739
- Testing
- Mediterranean diet
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara University
Parkinson's Disease
Cont. of a Study to Evaluate Implanting Peripheral Nerve Grafts Into Subjects With Parkinson's Disease (PD) During DBS
This pilot study is designed to follow up on a previous, preliminary study and test the long-term safety and feasibility of the implantation of autologous peripheral nerve grafts into the substantia nigra, basal forebrain…
- Trial name
- CAPNG (NCT02369003)
- Testing
- Autologous Peripheral Nerve Graft
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Craig van Horne, MD, PhD
Parkinson's Disease Patients Undergoing Deep Brain Stimulation (DBS) Surgery
Invasive Approach to Model Human Cortex-Basal Ganglia Action-Regulating Networks
The brain networks controlling movement are complex, involving multiple areas of the brain. Some neurological diseases, like Parkinson's disease, cause abnormalities in the brain networks.
- Trial name
- NCT03608228
- Testing
- Measuring electrical signals from the brain
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Los Angeles
Parkinson's Disease
Autologous Peripheral Nerve Grafts Into the Substantia Nigra of Subjects With PD Undergoing Deep Brain Stimulation
By doing this study, the investigators hope to learn provide safety data that can be used to generate a larger phase III clinical trial.
- Trial name
- NCT01833364
- Testing
- Implantation of the Peripheral Nerve Graft
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Craig van Horne, MD, PhD