Clinical trials: Ubiquinol
Gulf War Illness, Chronic Fatigue
Coenzyme Q10 Phase III Trial in Gulf War Illness
The primary objective of this clinical trial is to determine if treatment with ubiquinol, a form of coenzyme Q10, improves the physical function of men and women Veterans suffering from Gulf War Illness (GWI).
- Conditions
- Gulf War Illness, Chronic Fatigue, Ubiquinol, Coenzyme Q10
- Trial name
- NCT02865460
- Testing
- Ubiquinol
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- VA Office of Research and Development
Coenzyme Q10, Oxidative Stress
Bioavailability and Impact of Coenzyme Q10 in Stressing Exercise in Senescence Athletes
It is proposed to establish a group of subjects composed of 10 healthy individuals of> 50 years and <65, physically active, without metabolic or inflammatory pathology.
- Conditions
- Coenzyme Q10, Oxidative Stress, Aging
- Trial name
- CoQ10Sport (NCT03893864)
- Testing
- Administration of a product with Fitosomed Ubiquinone, Coenzyme Q10 level in muscle biopsies, Coenzyme Q10 level in plasma, blood cells, urine cells
- Where
- Spain
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Centre d'Alt Rendiment
Heart Failure
Ubiquinol Treatment in Patients With Heart Failure and Preserved Ejection Fraction
There are no studies specifically examining the effects of coenzyme Q (CoQ) treatment on echocardiographic indices of diastolic function in elderly patients with heart failure with preserved ejection fraction (HFPEF).
- Trial name
- NCT02779634
- Testing
- ubiquinol
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
Oligospermia, Sperm Count, Low
Creatine and Ubiquinol for Sperm Quality
This randomized controlled double-blind parallel-group interventional trial explores the impact of 8-week creatine supplementation, with or without ubiquinol, on sperm quality biomarkers in normospermic and oligospermic men.
- Trial name
- CRESPAQ10 (NCT06202469)
- Testing
- Supplement 1, Supplement 2
- Where
- Serbia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Parkinson Disease
Ubiquinol in Parkinson's Disease: Safety, Tolerability, and Effects Upon Oxidative Damage and Mitochondrial Biomarkers
The purpose of this study is to find out whether ubiquinol is well tolerated, can affect the symptoms of Parkinson's Disease and change the energy levels in the brain.
- Trial name
- NCT03061513
- Testing
- Ubiquinol
- Volunteers
- 11 people
- Sponsor
- Weill Medical College of Cornell University
Autism Spectrum Disorder, Phelan-McDermid Syndrome
Q10 Ubiquinol in Autism Spectrum Disorder and in Phelan-McDermid Syndrome.
This double-blind, cross-over, randomized, controlled trial (RCT) has the aim of evaluating the effectiveness of a metabolic support therapy in two cohorts of patients with idiopathic Autism Spectrum Disorder or Phelan-McDermid…
- Trial name
- Q10ASD (NCT04312152)
- Testing
- Q10 Ubiquinol, Vitamin E, Multi-Vitamin B complex
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Antonio Persico
Absorption
Bioavailability of Ubiquinone and Ubiquinol in Older Adults
Coenzyme Q10 (or CoQ10) is a marketed supplement in US even though it can be synthesized in the body via complicated biochemical pathways.
- Trial name
- NCT03020680
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Tufts University
IVF
Ubiquinone vs. Ubiquinol Supplementation
The objective of this study is to determine if ubiquinol will result in improved reproductive outcomes in older women at a reduced oral dose compared to current standard treatment with ubiquinone.
- Trial name
- NCT06555575
- Testing
- Ubiquinone 200 Mg Oral Capsule, Ubiquinol 100 MG Oral Capsule
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Trio Fertility
Tinnitus
The Effect of Coenzyme Q10 on Hearing and Tinnitus Characteristics of Chronic Tinnitus Patients
The study is a randomised double-blinded trial. A group of 40 tinnitus patients with a naturally low Q10 level will be selected out of a preselected group of 160 screened out of a pre-existed database or patients which visited…
- Trial name
- NCT02353650
- Testing
- Q10
- Where
- Belgium
- Sponsor
- University Hospital, Antwerp
Heart Failure, Diastolic
CoQ10 and D-ribose in Patients With Diastolic Heart Failure
The purpose of this study is to compare the clinical benefits of CoQ10 and D-ribose taken by patients who have diastolic heart failure, or heart failure with preserved ejection fraction (HFpEF).
- Trial name
- NCT03133793
- Testing
- CoQ10, D-Ribose Oral Powder
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Huntington Disease
Bioavailability of Ubiquinol in Huntington Disease
The death of brain cells in Huntington Disease (HD) is thought to be associated with a lack of normal cell energy and harmful brain substances called free radicals.
- Trial name
- NCT00980694
- Testing
- ubiquinol
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Rochester
Sepsis
Ubiquinol (Reduced COQ10) for Patients With Sepsis
This study aims to determine if Ubiquinol (reduced form of COQ10) will attenuate mitochondrial injury and decrease inflammatory response in patients suffering from sepsis.
- Trial name
- NCT01948063
- Testing
- Ubiquinol
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Beth Israel Deaconess Medical Center
Diabetes
Water-soluble Ubiquinol Supplementation on Blood Glucose, Lipids, Oxidative Stress, and Inflammation in Diabetes
Diabetes is considered an oxidative stress and a chronic inflammatory disease. Coenzyme Q10 (ubiquinone) is recognized as a lipid soluble antioxidant.
- Trial name
- NCT02622672
- Testing
- water-soluble ubiquinol
- Volunteers
- 50 people
- Sponsor
- Yeh
Borderline High LDL-cholesterol
Effects of Ubiquinol and Ubiquinone on Vascular Function in Healthy Adults With Borderline High LDL-Cholesterol
This randomized, double-blind, placebo-controlled clinical trial will evaluate the effects of Ubiquinol and Ubiquinone on vascular endothelial function in generally healthy adults with borderline high LDL-cholesterol.
- Trial name
- NCT07881601
- Testing
- Ubiquinol, Ubiquinone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- SF Research Institute, Inc.
Acne
Clinical Observation of Skin Condition in Patients With Acne Vulgaris Using Ubiquinol, Pomegranate Peel Extract, Ceramide, and Salicylic Acid Emulsion
The goal of this observational study is to evaluate the efficacy and tolerability of a lotion containing panthenol, pomegranate peel extract, ceramides, salicylic acid and Phylobioma (La Roche-Posay Effaclar Duo+M) used in…
- Trial name
- NCT07735169
- Volunteers
- 40 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Pediatric Dilated Cardiomyopathy
Potential Role of Water-soluble Ubiquinol in Complementary Therapy for Pediatric Dilated Cardiomyopathy
Pediatric dilated cardiomyopathy (PDCM) is the most common form fond in children. Water-soluble coenzyme Q10 (ubiquinol) is better absorbed than lipid-soluble coenzyme Q10 (ubiquinone) and is directly involved in the antioxidant…
- Trial name
- NCT02847585
- Testing
- Water-soluble Ubiquinol
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Chung Shan Medical University
Coenzyme Q10 Pharmacokinetics
Pharmacokinetics of Different CoQ10 Formulations
The objective of this trial is to compare the bioavailability (AUC, Tmax, and Cmax) of different Coenzyme Q10 preparations in healthy adults.
- Trial name
- NCT06151171
- Testing
- CoQ10
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Factors Group of Nutritional Companies Inc.
Polycystic Ovarian Syndrome
Effect of Ubiquinol Supplementation on Ovulation Induction in Clomiphene Citrate Resistance
Objective: To evaluate potential benefits of adding the active form of Coenzyme Q10 (Ubiquinol) to Clomiphene Citrate compared with Human Menopausal Gonadotropins (hMG) in Clomiphene Citrate resistant PCOS patients.
- Trial name
- NCT04870502
- Testing
- Controlled ovarian stimulation by Combined Clomiphene Citrate and Ubiquinol Versus hMG
- Where
- Saudi Arabia
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Saudi German Hospital - Madinah
Wellness, Health
Comparing the Effects of Commercially Available Dietary Supplements on CoQ10 Concentrations
The primary purpose of this study is to compare the safety and effectiveness of commercially available dietary supplements believed to increase coenzyme Q10 (CoQ10) concentrations.
- Trial name
- NCT06640465
- Testing
- Ubiquinol + geranylgeraniol, Geranylgeraniol, Ubiquinol
- Where
- 6 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- OvationLab
Health Status
Observational Study to Evaluate the Quality of Life of Healthy Postmenopausal Women Who Take Coenzyme Q-Ubiquinol
Observational study about quality of life in postmenopausal women taking coenzyme Q compared to another group of women of the same age who do not take it
- Trial name
- NCT03429231
- Testing
- Coenzima Q - QubiquinolCoenzyme Q - Qubiquinol
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Dr. Santiago Palacios