Clinical trials: Typically Developing Children
Undiagnosed Disease, Healthy Volunteer (Adult With Typically Developing Child)
Inherited Diseases, Caregiving, and Social Networks
Approximately 66 million informal caregivers care for someone who is ill, disabled, or aged. These caregivers experience significant distress associated with caregiving, which may be particularly salient in the context of…
- Conditions
- Undiagnosed Disease, Healthy Volunteer (Adult With Typically Developing Child), Inherited Neurodegenerative Disorders, Inherited Metabolic Disorders (Inborn Errors of Metabolism)
- Trial name
- NCT01498263
- Where
- 2 sites in United States
- Volunteers
- 682 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Typically Developing Children Ages 3 to 6
Language Learning and Language Experience
The goal of this clinical trial is to learn if text can support children in learning new verbs in healthy children ages three through six.
- Trial name
- NCT06645145
- Testing
- Orthographic facilitation
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Montclair State University
Autism
Social Cognition in Children and Adolescents With Autism Spectrum Disorder
This study aims to (1) characterize the multi-domain social cognitive profile and developmental trajectory of children with autism spectrum disorder (ASD) aged 2.5 to 14 years relative to typically developing peers; (2) establish…
- Trial name
- NCT07692022
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Nonorganic Insomnia, Primary Insomnia
Better Nights, Better Days for Typically Developing Children
Up to 25% of children suffer from sleep problems categorized as "insomnia": difficulty settling, falling asleep, and staying asleep.
- Trial name
- BNBD (NCT02243501)
- Testing
- Intervention Group
- Where
- Canada
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Meningomyelocele
Dual Task and Upper Extremity Performance in Children With Myelomeningocele
Myelomeningocele is a neural tube defect caused by the failure of the neural tube to close in the caudal part. The exposed spinal cord in myelomeningocele usually causes neural damage.
- Trial name
- NCT06949475
- Testing
- Single Task (Box and Block Test), Single Task (Nine Hole Peg Test), Dual Task (Box and Block Test-Kognitif Task)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Children, Muscle Strength
Reliability and Validity of Strength Measurement of the Lower Limbs in Typically Developing Children
Reliability of isokinetic strength measurement of the knee in typically developing children has yet been studied and seems to be good.
- Conditions
- Children, Muscle Strength, Reproducibility of Results, Muscle Strength Dynamometer
- Trial name
- NCT04024592
- Testing
- Biodex System 4
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Ghent
Children
Effects of Transcranial Random Noise Stimulation on Motor Learning in Typically Developing Adolescents
The goal of this study is to compare motor learning rates on two different tasks, when combined with non-invasive brain stimulation.
- Trial name
- NCT06267339
- Testing
- transcranial random noise stimulation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Burke Medical Research Institute
Cerebral Palsy (CP), Typically Developing Children
Interaction Between Spasticity and the Initial Response After Balance Perturbations in Children With Spastic Cerebral Palsy
The aim of this study was to investigate the link between spasticity and the initial response after standing balance perturbations in children with spastic cerebral palsy.
- Trial name
- NCT07616193
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
ASD
Differences in N-CAD Concentration and Brain Function Between Children With ASD and TD
The incidence of autism spectrum disorders is increasing, about 1 / 36. Neural cadherin (NCAD) is closely related to synaptic structure and function.
- Trial name
- NCT07400484
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Chen Li
Autism Spectrum Disorder (ASD)
Internalized Symptoms in Adolescents With Autism Spectrum Disorder (ASD) and Typically Developing Adolescents : Gaining Insight Into Coping Strategies and the Psychological Processes Involved
Introduction: Adolescents with autism spectrum disorder (ASD) have more mental health problems than typically developping adolescents (without ASD).
- Trial name
- NCT07360223
- Testing
- Questionnaire and interview
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Autism Spectrum Disorder
MRI Study of Subjects with ASD, Their Relatives and TD
This project is structured around a central study called "Study of genetic factors involved in autism and related conditions ("Genes and Autism" study, sponsor: INSERM).
- Trial name
- NCT05470088
- Testing
- Neuroimaging (MRI)
- Where
- 2 sites in France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Gait
Dual-tasking Effect on Gait in Children With Developmental Coordination Disorder
The aim of the study is to collect data in children with developmental coordination disorder (DCD) aged between 7 and 17 years for analyses of the gait pattern while walking at the Gait Real-time Analysis Interactive Lab (GRAIL)…
- Trial name
- NCT06400043
- Testing
- Cognitive dual-task, Motor dual-task
- Where
- 2 sites in Belgium
- Volunteers
- 23 people
- Sponsor
- University Ghent
Executive Dysfunction, Motor Activity
The Role of Brain-derived Neurotropic Factor in the Relationship Between Executive Function and Physical Training
This doctoral thesis has the aim to identify the role of Brain-derived neurotropic factor in the relationship between physical fitness/activity and executive functions in typically developing children and children with Autism…
- Conditions
- Executive Dysfunction, Motor Activity, Child
- Trial name
- NCT02503579
- Testing
- physical training
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University Ghent
Growth, Child Development
Growth and Body Composition in Children
This study is planned to measure and compare body composition indexes and growth between typically developing children and those with disabilities in South Korea for understanding the nutritional and growth status.
- Conditions
- Growth, Child Development, Disability, Developmental
- Trial name
- NCT03653754
- Testing
- Measurement of growth and body composition
- Where
- South Korea
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Healthy Children
Fine Motor Performance in School-aged Children
The goal of this observational cross-sectional study is to investigate the relationship between core stability, hand grip strength, and handwriting performance in typically developing school-aged children aged 8 to 12 years.
- Trial name
- HGS/HLS (NCT07767656)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cerebral Palsy, Typically Developing Children
Repetitive Transcranial Magnetic Stimulation on Motor Function and Meta-Plasticity in Cerebral Palsy: TMS-EEG Study
This project examines the use of repetitive transcranial magnetic stimulation (rTMS) as a therapeutic approach to improve motor function in children with cerebral palsy (CP).
- Trial name
- NCT07567053
- Testing
- MRI, HD-EEG Recording, rTMS
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cook Children's Health Care System
Mental Disorders
Effects of Emotion on Episodic Memory in Typically Developing Children and Children With Williams-Beuren Syndrome
It's well established in the literature that emotional events are more likely to be remembered than neutral events. Although this Emotional Enhancement of Memory (EEM) has been well demonstrated in the adult literature, little is…
- Trial name
- EEM-TAdev (NCT03688516)
- Testing
- Manipulation of valence and modality, Spatial and recognition memory, Source and content memory
- Where
- France
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Cerebral Palsy, Infant Development
Neuroimaging of Babies During Natural Sleep to Assess Typical Development and Cerebral Palsy
Background: Early diagnosis of cerebral palsy (CP) is crucial, enabling intervention when neuroplasticity is at its highest. Magnetic resonance imaging (MRI) plays a vital role in CP diagnosis.
- Conditions
- Cerebral Palsy, Infant Development, Development, Infant
- Trial name
- NIBS-CP (NCT06396520)
- Testing
- No intervention, observational
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Danish Research Centre for Magnetic Resonance
Bilingualism, Vocabulary Acquisition
Word Learning in Bilingual Typical and Late Talking Children: The Role of Meaning and Input
The goal of this clinical trial is to understand how different types of word categories, along with the language children hear from their parents, support bilingual toddlers' word learning.
- Conditions
- Bilingualism, Vocabulary Acquisition, Late Talkers, Network Science
- Trial name
- NCT07600242
- Testing
- Large Semantic Category Condition, Small Semantic Category Condition
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Pregnancy, Autistic Disorder
Screening for Metabolic Problems in Mothers of Children With Autism and Typically Developing Children
The purpose of this research study is to screen for metabolic abnormalities that are maternal risk factors for having a child with autism.
- Conditions
- Pregnancy, Autistic Disorder, Folic Acid Deficiency
- Trial name
- NCT02674022
- Testing
- Prenatal supplement
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic