Clinical trials: Type1diabetes
Type 1 Diabetes, type1diabetes
Reducing Innate Inflammation in New Onset Type 1 Diabetes
This study aims to determine whether Lactiplantibacillus plantarum 299v (Lp299v) supplementation will reduce systemic inflammation and prolong residual beta cell function in individuals newly diagnosed with Type 1 diabetes.
- Conditions
- Type 1 Diabetes, type1diabetes, Type 1 Diabetes Mellitus
- Trial name
- NCT04335656
- Testing
- Lactiplantibacillus plantarum
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Medical College of Wisconsin
Non-Nutritive Sweetener, Type 1 Diabetes
Cardiometabolic Effects of Non-Nutritive Sweeteners (NNS) in Type 1 Diabetes (T1D)
This project will apply a novel non-nutritive sweetener (NNS) dietary assessment tool with measurement of circulating NNS levels in a pediatric population, allowing correlation of NNS exposure to clinically meaningful…
- Conditions
- Non-Nutritive Sweetener, Type 1 Diabetes, type1diabetes, Type 1 Diabetes Mellitus
- Trial name
- NCT07434544
- Testing
- Cherry Sports Drink
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Type1diabetes
Teamwork, Targets, Technology, and Tight Control in Newly Diagnosed Pediatric T1D - 4T Study
The 4T program encompasses: Teamwork, Targets, Technology, and Tight Range. These methods will help patients better manage their condition of Type 1 Diabetes with improved patient-reported outcomes.
- Trial name
- NCT04336969
- Testing
- 4T Education and Care
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- Stanford University
Type1diabetes, Fatty Liver
Night Hyperglycemia and Fatty Liver in Type 1 Diabetes
This clinical trial aims to discover the relationship between hyperglycemia at night and early morning hours and the presence of fatty liver in patients with type 1 diabetes.
- Trial name
- NCT05933018
- Testing
- liver elastography
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- HaEmek Medical Center, Israel
Diabetes, Type1diabetes
Continuous Ketone Monitoring in People With Type 1 Diabetes Using SGLT2 Inhibitors
Type 1 diabetes is an autoimmune disease where the body attacks the insulin-producing cells in the pancreas. In the absence of insulin, the body is unable to effectively use glucose for energy, resulting in high blood sugar…
- Conditions
- Diabetes, Type1diabetes, T1D
- Trial name
- EmpaCKM (NCT06753994)
- Testing
- SGLT-2 inhibitor
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- McGill University
Type1diabetes
Safety and Effectiveness of A Novel Continuous Glucose and Ketone Monitoring System
The study is to evaluate the accuracy and safety of a novel real-time continuous glucose and ketone monitoring system among adult patients with type 1 diabetes mellitus (T1DM) with respect to Yellow Spring Instrument (YSI) and…
- Trial name
- NCT07139808
- Testing
- GK5 CGKM
- Where
- 2 sites in China
- Volunteers
- 12 people
- Sponsor
- Henan University of Science and Technology
Type1diabetes
Thrive With Type 1 Diabetes 2026
This study aims to learn whether a cognitive behavioral intervention can improve lifestyle and glucose targets for adults with type 1 diabetes.
- Trial name
- NCT07522866
- Testing
- TranS-C Intervention Arm, Attention Control Enhanced Usual Care (EUC) Arm
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Emory University
type1diabetes, CGM
Evaluation of the Accuracy and Safety of a Continuous Glucose Monitoring System
The study is to evaluate the accuracy and safety of a real-time CGM system among adult patients with type 1 diabetes with respect to reference venous plasma sample measurements.
- Conditions
- type1diabetes, CGM, T1D
- Trial name
- NCT07745244
- Testing
- GS3 CGM
- Where
- China
- Volunteers
- 36 people
- Sponsor
- SiBionics, Co, Ltd
type1diabetes, Obesity
Physiologic Markers of Cardiometabolic Risk in People With Type 1 Diabetes
More than 40% of young adults with type 1 diabetes (T1D) also have overweight or obesity. Each of these diagnoses increase the risk of adverse cardiovascular events.
- Trial name
- NCT06105931
- Testing
- Hyperinsulinemic-euglycemic clamp, High Fat Mixed Meal Tolerance Test
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yale University
Type1diabetes
Comparison of Low, Moderate and High Carbohydrate Diet on Insulin Requirements and Metabolic Control in Type 1 Diabetes
The scientific basis for dietary recommendations in type 1 diabetes is almost lacking, with the current recommendations being based on type 2 diabetes studies.
- Trial name
- DANCE (NCT03761186)
- Testing
- traditional diabetes diet, moderately low carbohydrate diet, strictly low carbohydrate diet
- Where
- Sweden
- Volunteers
- 103 people
- Sponsor
- Anneli Björklund
Type1diabetes
SGLT2i, Pioglitazone, and Ketone Production in T1D
Participants are being asked to be in a research study. Scientists do research to answer important questions which might help change or improve treatment of participants disease in the future.
- Trial name
- NCT07056699
- Testing
- Dapagliflozin 10mg Tab, Pioglitazone 15 MG and 30mg
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Type1diabetes, Hypoglycemia
Galactose - the Ideal Carbohydrate Supplement for Exercise in Type 1 Diabetes
In this study, 14 subjects with type 1 diabetes are studied in a randomized crossover study in which the subjects cycle at a fixed intensity at 60% of their maximum oxygen capacity (VO2 max) for 1 hour.
- Conditions
- Type1diabetes, Hypoglycemia, Hyperglycemia
- Trial name
- NCT05557227
- Testing
- 1-hour cycling
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- University of Aarhus
Type1diabetes
Morning Versus Afternoon Aerobic Exercise in Type 1 Diabetes
Aim. To determine whether the need for exogenous carbohydrate supplementation during exercise in type 1 diabetes is lower during morning exercise compared to afternoon exercise, and whether this is associated with greater lipid…
- Trial name
- NCT06115616
- Testing
- Morning exercise, Afternoon exercise
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Type1diabetes
Evaluation of the Accuracy and Safety of A Novel Real-Time Continuous Glucose Monitoring System
The study is to evaluate the accuracy and safety of a novel real-time CGM system among adult patients with type 1 diabetes mellitus with respect to YSI reference venous plasma sample measurements.
- Trial name
- NCT07092761
- Testing
- GS3 CGM
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Henan University of Science and Technology
Diabete Mellitus, Type2diabetes
CGM Experience, Preferences & Blood Glucose Parameters
This is an open-label, prospective, multicenter observational study designed to evaluate the perceived benefits, device experience, preference, and glucose-related parameters associated with the Instara-1 Continuous Glucose…
- Conditions
- Diabete Mellitus, Type2diabetes, type1diabetes, Gestational Diabetes
- Trial name
- NCT07607015
- Testing
- CGM
- Volunteers
- 75 people
- Sponsor
- Getz Pharma
Type1diabetes
Exercise Training and Endothelial Function in Type 1 Diabetes
Endothelial dysfunction and vasoreactivity disorders are early subclinical complications of type 1 diabetes (T1D). In a preventive setting, in T1D patients still free of complications, the research of non-pharmacological…
- Trial name
- EVaDia (NCT03528226)
- Testing
- Exercise Training Procedure, Normal life procedure
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Lille
type1diabetes, Renal Failure
Kidney Alone Versus Islet-After-Kidney in Type 1 Diabetic Kidney Transplant Recipient.
Islet transplantation is associated with a benefit on glycaemic control compared to optimized insulin therapy in recent clinical trials.
- Conditions
- type1diabetes, Renal Failure, End Stage Renal Disease
- Trial name
- KA-IAK (NCT05662267)
- Testing
- Pancreatic islet transplantation after kidney transplantation
- Where
- France
- Volunteers
- 327 people
- Sponsor
- University Hospital, Lille
type1diabetes
Remote Digital Care Effects in Adolescents With Type 1 Diabetes
Pilot study to evaluate effects of an experimental additional remote digital care (TELEDUC-DIAB) to adolescents with poorly controlled type 1 diabetes using digital monitoring platform and educative app
- Trial name
- TELEDUC-DIAB1 (NCT05421715)
- Testing
- TELEDUC-DIAB
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Toulouse
Type1diabetes, Insulitis
Pancreas Ultrasound Imaging in type1 Diabetes
The overall goal of this study is to develop and test a novel method involving ultrasound imaging, in order to detect the development of type 1 diabetes.
- Conditions
- Type1diabetes, Insulitis, Pancreas Inflamed
- Trial name
- NCT05482321
- Testing
- Definity Suspension for Injection
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Type1diabetes
Type 1 Diabetes Education and Support Study
Diabetes distress has been identified as one of the largest contributors to the racial disparity in glycemic control that disproportionately burdens Black patients ages 18-30 years with type 1 diabetes (T1D).
- Trial name
- T1DES (NCT05735340)
- Testing
- Diabetes Education, T1DES
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Kaiser Permanente