Clinical trials: Type 2 Diabetes Mellitus Remission
Type 2 Diabetes
The Impact of Diabetes Remission on Aging
This study is a real-world, prospective clinical cohort study. It will enroll Chinese patients with type 2 diabetes. The aim is to assess the changes in aging biomarkers, primarily DunedinPACE, from baseline to post-remission…
- Trial name
- NCT07736040
- Testing
- Comprehensive Lifestyle Intervention
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Morbid Obesity, Type2 Diabetes
Elucidating the Mechanism of Remission of Type 2 Diabetes in Morbid Obese Patients After Bariatric Surgery
The main aim of this study is to elucidate the mechanism of the remission of type 2 diabetes in the morbid obese patients after laparoscopic sleeve gastrectomy.
- Trial name
- NCT03038373
- Testing
- Laparoscopic Sleeve Gastrectomy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Dasman Diabetes Institute
Diabetes Mellitus, Type 2, Bariatric Surgery
Comparisons of Metabolic Effect of Sleeve Gastrectomy With Duodenojejunal Bypass and Sleeve Gastrectomy (MEDUSA): A Multicenter Randomized Controlled Trial
In this study, the effects of SG with DJB and SG alone for the treatment of type 2 diabetes mellitus (T2DM) will be compared in patients other than the two groups at both extremes who are expected to show excellent effects of…
- Conditions
- Diabetes Mellitus, Type 2, Bariatric Surgery, Surgical Procedures, Operative, Asians
- Trial name
- NCT05211375
- Testing
- Duodenojejunal bypass, Sleeve gastrectomy
- Where
- South Korea
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Type 2 Diabetes
Pancreas Lipotoxicity in T2D: Edinburgh Diabetes Remission Study (EDRS)
This study aims to investigate how fat accumulation in the pancreas contributes to the development of type 2 diabetes (T2D), and how weight loss may reverse this process.
- Trial name
- EDRS (NCT07364045)
- Testing
- Total Diet Replacement (TDR) Program
- Where
- United Kingdom
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Diabetes Mellitus, Type 2
The eHealth Diabetes Remission Trial
Overweight patients with type 2 diabetes are offered a total diet replacement with the goal of weight loss and diabetes remission.
- Trial name
- eDIT (NCT05491005)
- Testing
- Total diet replacement, eHealth, Face-to-face
- Where
- 3 sites in Sweden
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Umeå University
Type2diabetes, Disordered Eating
ARIADNE: A Study of Weight Loss for Diabetes Treatment and Wellbeing
The NHS has started a trial-run of a weight loss programme replacing food with 800-calorie shakes and soups for 3 months, offered to people with newly diagnosed type 2 diabetes (T2D) to lose weight and put their diabetes into…
- Conditions
- Type2diabetes, Disordered Eating, Obesity, Overweight and Obesity
- Trial name
- NCT05744232
- Testing
- Low calorie total diet replacement, Usual care
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Diabetes Mellitus, Type 2, Obesity
Who Will Benefit From Bariatric Surgery for Diabetes?
A study investigating the influence of fat distribution, genetic susceptibility markers for type 2 diabetes (T2DM) and fat distribution, epigenetic and transcriptomic changes and gut hormone responses to a mixed meal on diabetes…
- Trial name
- NCT03842475
- Testing
- Roux-en-Y gastric bypass (RYGB)
- Where
- United Kingdom
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Newly Diagnosed Type 2 Diabetes, Obese
Pathobiology of Remission of Type 2 Diabetes
We propose to investigate effects of HP and HC weight loss diets in Newly Diagnosed T2DM (NT2DM) women and men for 6 months for remission of Type 2 Diabetes.
- Trial name
- NCT03832725
- Testing
- High Protein (HP) weight loss diet, High carbohydrate (HC) weight loss diet
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Diabetes Mellitus Type 2
Adipose Tissue Storage in the Rapid Remission of Hepatic and Cardiac Metabolic Dysfunction After Bariatric Surgery
The present protocol aims to understand and establish whether there is a causal link between adipose tissue metabolic remodeling and Type 2 Diabetes (T2D) remission after bariatric surgery.
- Trial name
- CB5 (NCT05934409)
- Testing
- Bariatric surgery, Nicotinic Acid
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Diabetes Mellitus, Type 2, Obesity
Microbiome and Health Indicators in People With Obesity, Prediabetes and Type 2 Diabetes Undergoing a Lifestyle Intervention
The incidence of type 2 diabetes worldwide is growing rapidly, being one of the fastest growing global health emergencies of the 21st century according to the International Diabetes Federation.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, PreDiabetes
- Trial name
- MicrobiAr (NCT05372445)
- Testing
- Non-intensive intervention, Intensive intervention
- Where
- Argentina
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- National Council of Scientific and Technical Research, Argentina