Clinical trials: Type 2 Diabetes Mellitus Remission
Type 2 Diabetes Mellitus
The Progress of Diabetes After Supaglutide Treatment in Type 2 Diabetes Patients
Glucagon like peptide-1 receptor agonist (GLP-1RA) can enhance insulin secretion and inhibit glucagon secretion in a glucose concentration dependent manner, delay gastric emptying, and reduce food intake through central appetite…
- Trial name
- NCT06605287
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Diabetes Mellitus, Type 2, Obesity
Effectiveness of a Weight Management Programme on Diabetes Remission in Obese Patients With Early Diabetes
The goal of this clinical trial is to determine the effectiveness of a weight management programme in primary care in achieving diabetes remission in obese patients with early diabetes.
- Trial name
- NCT05762120
- Testing
- Weight Management Programme
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- National Healthcare Group Polyclinics
Obesity, Diabetes Mellitus Type 2 in Obese
Deciphering the Role of Incretin Hormones in Weight Loss-induced Remission of Type 2 Diabetes (DIABeat)
The goal of this mechanistic study is to investigate the role of incretin hormones on weight loss-induced type 2 diabetes remission.
- Trial name
- DiabEATit (NCT06333132)
- Testing
- Weight loss-induced Diabetes Remission
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Diabetes Mellitus, Type 2
Mazdutide for Remission of Type 2 Diabetes: Multicentre, Double Blind, Randomised, Placebo Controlled Trial
The purpose of this study is to investigate and efficacy of Mastitide for diabetes remission in Chinese type 2 diabetic subjects with poor glycemic control on diet or exercise therapy alone or metformin/sodium-glucose…
- Trial name
- NCT07767552
- Testing
- Mazdutide
- Where
- China
- Volunteers
- 249 people
- Sponsor
- Yanbing Li
Type 2 Diabetes
Effect on Beta Cell Function and Glycaemic Control After Insulin and Exenatide Sequential Therapy
Whether GLP-1 receptor agonists sequential therapy in newly diagnosed type 2 diabetic patients can further improve glycemic control, diabetes remission rate and β-cell function after the short-term insulin intensive therapy.
- Trial name
- T2DMRS (NCT02129985)
- Testing
- Exenatide, Metformin
- Where
- China
- Volunteers
- 100 people
- Sponsor
- xiaolong zhao
Type 2 Diabetes Mellitus Remission
Type 2 Diabetes Remission
The study aims to establish a cohort of patients with type 2 diabetes (T2D) who have achieved remission through lifestyle intervention or bariatric surgery.
- Trial name
- NCT06177210
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Diabetes Mellitus Type 2
Effects on Remission of Type 2 Diabetes Mellitus Following Gastric Bypass Alone vs Gastric Bypass Combined With Truncal Vagotomy
This randomized, triple-blind clinical trial investigates whether adding truncal vagotomy to Roux-en-Y gastric bypass (RYGB) enhances remission of type 2 diabetes mellitus (T2DM) in patients with obesity.
- Trial name
- VagusSx (NCT07278115)
- Testing
- Roux-en-Y Gastric Bypass plus Truncal Vagotomy, Roux-en-Y Gastric Bypass
- Where
- 2 sites in Greece
- Volunteers
- 40 people
- Sponsor
- University Research Institute for the Study of Genetic & Malignant Disorders in Childhood
Diabetes Mellitus, Type 2
Effect of Liraglutide Combined With Short-term CSII on Long-term Glycemic Remission and β Cell Function
The purpose of this study is to investigate and evaluate the effects of liraglutide combined with short-term continuous subcutaneous insulin infusion(CSII) on long-term glycemic control and β-cell function in newly diagnosed type…
- Trial name
- NCT01790308
- Testing
- CSII, Liraglutide
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Type 2 Diabetes
Triple Hypoglycemic Regimens In Patients With Newly Diagnosed Type 2 Diabetes Mellitus
This study is a multicenter, randomized, controlled study. A sample size of 240 cases is proposed to be included. The inclusion criteria are: (1) patients with newly diagnosed type 2 diabetes; (2) age between 18 and 65 years old…
- Trial name
- TRED (NCT07374328)
- Testing
- Semaglutide (1 Mg Dose), Sitagliptin (DPP4 inhibitor)
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Obesity, Diabetes Mellitus, Type 2
Weight Management for the Remission of Type 2 Diabetes Using a Proprietary Meal Replacement System- Diabetes Remission Study (DRS)
A three month meal replacement dietary system which combines meal replacements and self-prepared meals which hypothetically will result in Diabetes remission in >30% of intervention subjects To assess the efficacy of which…
- Trial name
- DRS (NCT05397028)
- Testing
- Meal replacement system, Intensive lifestyle Intervention
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Loma Linda University
Type 2 Diabetes
DiEt ChoIce to Promote Type 2 Diabetes rEmission
Type 2 diabetes is typically viewed as a chronic, progressive, and lifelong condition. Patients and their healthcare providers "manage" type 2 diabetes through lifestyle modifications and various types of medications designed to…
- Trial name
- DECIDE (NCT05710900)
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Newly Diagnosed Type 2 Diabetes, Obese
Pathobiology of Remission of Type 2 Diabetes
We propose to investigate effects of HP and HC weight loss diets in Newly Diagnosed T2DM (NT2DM) women and men for 6 months for remission of Type 2 Diabetes.
- Trial name
- NCT03832725
- Testing
- High Protein (HP) weight loss diet, High carbohydrate (HC) weight loss diet
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Type 2 Diabetes
REMIssion of Type 2 Diabetes Between Intermittently Scanned Continuous Glucose Monitoring and Capillary Blood Glucose Monitoring When Added to Low-calorie Meal Replacement and Diabetes Self-management Education
The goal of the study is to evaluate the effectiveness of intermittently scanned continuous glucose monitoring compared to capillary blood glucose monitoring among people with type 2 diabetes initiating low calorie meal…
- Trial name
- REMIT2D isCGM (NCT07157384)
- Testing
- Low calorie meal replacement plan, Diabetes self management education, Intermittently scanned continuous glucose monitoring
- Where
- 6 sites in Canada
- Volunteers
- 176 people
- Sponsor
- LMC Diabetes & Endocrinology Ltd.
Diabetes Mellitus Type 2 in Obese, Hypertension
Vegetarian Ketogenic Diet VS Omnivore Ketogenic Diet - Protocol of a Keto-vege Diet for Remission of Type 2 Diabetes
Diabetes is one of the biggest public health challenges of the 21st century because of the costs associated with its management, which are estimated at more than three billion dollars per year in Quebec.
- Conditions
- Diabetes Mellitus Type 2 in Obese, Hypertension, Diabetes Mellitus Type 2 With Hyperglycemia, Inflammation
- Trial name
- DT2-OFF (NCT05579561)
- Testing
- Diet
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- BloomedIn
Diabetes Mellitus, Type 2
Digital, Blended Lifestyle Intervention for Type 2 Diabetes Remission
410 Dutch type 2 diabetes patients will be randomized using a 5:1 ratio to intervention group versus control, to a lifestyle intervention program given via a mobile application and digital platform.
- Trial name
- IBIDEM (NCT05346614)
- Testing
- Lifestyle intervention
- Where
- 4 sites in Netherlands
- Volunteers
- 410 people
- Sponsor
- Ancora Health B.V.
Diabetes Type 2, Obesity
Comparing High and Normal Protein Diets for the Dietary Remission of Type 2 Diabetes
The purpose of this study is to examine the impact of high protein (HP) vs. normal protein (NP) diets on weight loss, loss of fat free mass (FFM), and remission of type 2 diabetes (T2D) in individuals with T2D.
- Conditions
- Diabetes Type 2, Obesity, Diet Modification
- Trial name
- NCT03832933
- Testing
- High Protein Diet, Standard Protein Diet
- Where
- 2 sites in United States
- Volunteers
- 117 people
- Sponsor
- University of Alabama at Birmingham
Obesity & Overweight, Type 2 Diabetes
Effects of HIIT Following PTR Programme
Caloric restriction programmes are highly effective and safe interventions for inducing rapid weight loss and improvements in glycaemic control.
- Trial name
- HIITpostLCD (NCT07565935)
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Nottingham
Type 2 Diabetes Mellitus in Remission, Metabolic Associated Fatty Liver Disease
Prevalence of MAFLD in Patients With Type 2 Diabetes in Jiangsu Province of China
In 2019, the number of patients with diabetes was about 463 million in the world, accounting for 8.3% of the total population, and it is expected to rise to 578 million (9.2%) by 2030 and 700 million (9.6%) by 2045.
- Trial name
- NCT05597709
- Testing
- Ultrasound attenuation parameter measurement, fasting blood glucose and fasting insulin determination
- Where
- China
- Volunteers
- 2,900 people
- Sponsor
- Wuxi Hisky Medical Technology Co Ltd
Type 2 Diabetes
The eHealth Diabetes Remission Trial - Pilot Study
Ten study participants will consume a low-calorie total diet replacement for 12 weeks, have a 6-week food reintroduction phase (week 13-18) and continue with the weight loss maintenance phase until the end of the study (week…
- Trial name
- eDIT-pilot (NCT04805996)
- Testing
- Diabetes remission using total diet replacement and eHealth contact with the healthcare provider
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Julia Otten
Type 2 Diabetes Mellitus
Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Sitagliptin (REMIT-Sita)
The purpose of the study is to determine whether in patients with early type 2 diabetes,a short-term intensive metabolic intervention comprising of sitagliptin, metformin, basal insulin glargine and lifestyle approaches will be…
- Trial name
- NCT02623998
- Testing
- insulin glargine, sitagliptin/metformin, lifestyle therapy
- Where
- 6 sites in Canada
- Volunteers
- 102 people
- Sponsor
- Population Health Research Institute