Clinical trials: Type 2 Diabetes Mellitus (DM)
Diabetes Mellitus, Type 2, Insulin Resistance
KurCoSmart Effects on People With Type 2 DM
The investigators aim to evaluate the effect of curcumin and virgin coconut oil extract supplementation on people with type 2 DM, including blood glucose, HbA1c levels, inflammation, body weight and insulin resistance evaluation
- Conditions
- Diabetes Mellitus, Type 2, Insulin Resistance, Inflammation, Body Weight
- Trial name
- NCT05407467
- Testing
- Curcumin and virgin coconut oil extract (KurCo Smart)
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Sebelas Maret
Type 2 Diabetes Mellitus (DM)
Community-based, eHealth Supported Type 2 Diabetes Care by Lay Village Health Workers in Rural Lesotho
This cluster-randomized intervention is embedded in the ComBaCaL (Community-Based Chronic disease care Lesotho) cohort study (EKNZ ID AO_2022-00058, clinicaltrials.gov ID NCT05596773, Lesotho NH-REC ID 210-2022), a platform for…
- Trial name
- ComBaCaL DM (NCT05743387)
- Testing
- DM care package, Referral to the responsible health facility
- Where
- 2 sites in Lesotho, Switzerland
- Volunteers
- 252 people
- Sponsor
- University Hospital, Basel, Switzerland
Complications of Diabetes Mellitus, Diabetes Mellitus
Effect of Diacerein in the Metabolic Control of Patients With DM Type 2 and Secondary Failure to Metformin
Considering that, Diacerein is on the market for 16 years being used continuously in elderly patients with osteoarthritis without experience significant side effects, and considering the anti-hyperglycemic effect and the…
- Conditions
- Complications of Diabetes Mellitus, Diabetes Mellitus, Diabetes Mellitus, Type 2
- Trial name
- NCT03208309
- Testing
- Diacerein
- Where
- 3 sites in Brazil
- Volunteers
- 40 people
- Sponsor
- ANS Pharma
Diabetes Type 2, Diabetes
Study Evaluating the Metabolic Effects of pulsENDO Therapy in Adults With Type 2 Diabetes
This is a prospective, multicenter, randomized, double-blind, sham-controlled, adaptive study evaluating the pulsENDO system in individuals with type 2 diabetes (T2D) inadequately controlled on non-insulin glucose-lowering…
- Conditions
- Diabetes Type 2, Diabetes, Diabetes (DM), Weight Change
- Trial name
- pulsENDO (NCT07768631)
- Testing
- pulsENDO Therapy
- Volunteers
- 320 people
- Sponsor
- Endogenex, Inc.
Periodontitis, Diabetes Mellitus, Type 2
A Danish Nationwide Longitudinal Study on Prevalence of Periodontitis and Its Co-morbidities
The project (PlanPerioMed) is a register-based study evaluating the associations and patterns of health care delivery between periodontitis and medical diseases using data from the Danish dental record system Dentalsuite…
- Conditions
- Periodontitis, Diabetes Mellitus, Type 2, Cardiovascular Diseases, Rheumatoid Arthritis
- Trial name
- PlanPerioMed (NCT05574231)
- Testing
- Periodontal treatment
- Volunteers
- 4,000,000 people
- Sponsor
- University of Copenhagen
Type 2 Diabetes
Dynamic Responsiveness of Insulin Secretory Parameters To Sitagliptin and Glimeperide Administration in Type 2 DM
A multi-year clinical study to improve tools for measuring the function of insulin-producing beta cells in people with type 2 diabetes mellitus.
- Trial name
- NCT02443922
- Testing
- Glimepiride, Sitagliptin, Metformin
- Volunteers
- 100 people
- Sponsor
- Foundation for the National Institutes of Health
Atherosclerosis With Diabetes Mellitus and Fatty Liver
Relation Between Carotid Atheroscerosis With DM &Fatty Liver
To determine the risk of atherosclerosis in NAFLD patients who have T2DM by meauring Carotid intima media thickness (CIMT) using carotid doppler ultrasound.
- Trial name
- NCT05532553
- Testing
- Carotid Doppler U/S
- Volunteers
- 200 people
- Sponsor
- Assiut University
Chronic Kidney Disease(CKD), Type 2 DM
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)
IRIS-CKD is a two-program implementation study to improve guideline-recommended screening and treatment of chronic kidney disease (CKD) in individuals with type 2 diabetes (T2D) in the United States.
- Conditions
- Chronic Kidney Disease(CKD), Type 2 DM, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- IRIS-CKD (NCT06906640)
- Testing
- (IRIS-CKD Management Program): Education, (IRIS-CKD Management Program): GDMT
- Where
- 7 sites in United States
- Volunteers
- 212 people
- Sponsor
- Duke University
Type 2 Diabetes Mellitus (DM)
Mulligan Mobilization With Movement Versus Conventional Physiotherapy on Ankle Range of Motion, Mobility, Pain, and Quality of Life in Patients With Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus (T2DM) is a major global health concern associated with chronic hyperglycemia, oxidative stress, and accumulation of advanced glycation end-products, which impair connective tissue function and commonly…
- Trial name
- NCT07827625
- Testing
- Experimental, Control
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Ibadat International University, Islamabad
Type 2 Diabetes Mellitus, Hypertension
TAPESTRY With Health Connnectors for Diabetes Management
The TAPESTRY-HC-DM approach is designed to support self-management of chronic disease by strengthening connections between patients and the primary healthcare system through "health connectors" -both volunteers and technology…
- Trial name
- TAP-HC-DM (NCT02715791)
- Testing
- TAP-HC-DM, Usual Care
- Where
- 3 sites in Canada
- Volunteers
- 50 people
- Sponsor
- McMaster University
Vitamin D Deficiency, Diabetes
Vitamin D and Inflammatory Markers of Cardiovascular Disease in African Americans With Type 2 Diabetes
Recent clinical trials in non diabetics showed that vitamin D supplementation markedly reduced serum levels of C-reactive protein (CRP), interleukin-6, and tissue matrix metallo-proteinases.
- Trial name
- NCT01153243
- Testing
- Ergocalciferol
- Volunteers
- 117 people
- Sponsor
- Cook County Health
Blood Pressure
Lifestyle Changes in Patients With Type 2 Diabetes Mellitus and Hypertension
Data obtained in hypertensive patients without diabetes suggest that increased association of non-pharmacological treatment in patients with diabetes and hypertension may be associated with an improvement in blood pressure…
- Trial name
- NCT01461330
- Testing
- DASH diet plus exercise, ADA diet
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Type 2 Diabetes Mellitus, Diabetic Nephropathy
Study of FibroGen (FG)-3019 in Subjects With Type 2 Diabetes Mellitus and Kidney Disease on ACEi and/or ARB Therapy
The purpose of this study is to evaluate the effect of FG-3019 on diabetic kidney disease or diabetic nephropathy.
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Nephropathy, Diabetic Kidney Disease
- Trial name
- NCT00913393
- Testing
- FG-3019
- Where
- 28 sites in United States
- Volunteers
- 46 people
- Sponsor
- Kyntra Bio
Diabetes Mellitus, Type 2
DM-BOOST Para Latinx: a Diabetes Mellitus Program Using Behavioral Economics to Optimize Outreach and Self-management Support With Technology for Latinx Patients
The specific aims of this project are to culturally adapt the DM-BOOST intervention for Latinx patients, usability test 'DM-BOOST para Latinx' to optimize cultural appropriateness and patient engagement and conduct a feasibility…
- Trial name
- NCT05583877
- Testing
- Diabetes BOOST, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Daniel Amante
Appointments and Schedules, Diabetes Mellitus, Type 2
Using Mobile Phone Short Message Service (SMS) Reminders to Enhance Appointment Attendance in DM Patients
A randomized controlled trial of patients with type 2 diabetes mellitus with multiple appointments into short message service group and control group. The attendance rate of these two groups of patients will be compared.
- Trial name
- NCT03055702
- Testing
- Mobile phone text message reminder
- Where
- Hong Kong
- Volunteers
- 270 people
- Sponsor
- The University of Hong Kong
NAFLD, Diabetes Mellitus
Improving Detection and Evidence-based Care of NAFLD in Latinx and Black Patients With Type 2 Diabetes
The primary objective of this pilot study is to assess the feasibility and acceptability of an intervention for improved detection and evidence-based care of NAFLD in Latinx and Black patients with type 2 diabetes (T2D) in Duke…
- Trial name
- NAFLD-DM (NCT05844137)
- Testing
- NAFLD Education, diet/lifestyle support, T2D medication management
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Duke University
Obesity, Type 2 Diabetes
Maternal Adipose Tissue and Placental Dysfunction Programs the Fetus for Type 2 Diabetes (PlacentA-DM)
The purpose of this study is to discover the characteristics of pregnant women which increases risk for their babies to develop diabetes, later on in life.
- Trial name
- PlacentA-DM (NCT02211651)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Diabetes Mellitus, Type 2, Prediabetic State
PREDICT-DM: Community Pharmacy-Based Point-of-Care Testing for Undiagnosed T2DM
The goal of this observational study is to learn whether community pharmacy-based risk assessment and point-of-care HbA1c testing can help detect undiagnosed type 2 diabetes and prediabetes among adults in Irbid Governorate…
- Conditions
- Diabetes Mellitus, Type 2, Prediabetic State, Prediabetes / Type 2 Diabetes, T2DM
- Trial name
- PREDICT-DM (NCT07795918)
- Where
- Jordan
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Incretin Hormones Plasma Levels, Gastric Bypass Surgery
A Comparative Study Between Effect Of Mini-gastric Bypass and Single Anastmosis Sleeve Jujenal Bypass On Levels Of GLP-1, GIP, PYY, Insulin Resistance and Type II DM Resolution
The aim of this work is to compare the outcome of Single Anastomosis Sleeve Jejunal Bypass (SASJ) with One Anastomosis Gastric Bypass (OAGB) as regards effect on levels of GLP-1 mainly, PYY and GIP and subsequent effect on…
- Trial name
- NCT07475143
- Testing
- Single anastomosis sleeve jejunal bypass, One anastomosis gastric bypass
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Type 2 Diabetes, Obesity
The Effect of 3 Different Models of MNT on DM Control in Overweight Patients With T2DM
The American Diabetes Association (ADA), among other medical societies, is strongly recommending medical nutrition therapy (MNT) for prevention and management of type 2 diabetes.
- Trial name
- NCT02520050
- Testing
- Traditional MNT, Structured MNT, Structured MNT plus Weekly Support
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Joslin Diabetes Center