Clinical trials: Type 1 Diabetes Mellitis
Type 1 Diabetes Mellitis
Impact of Integrated Pet Care on Glycemic Control and Diabetes Responsibility
The goal of this clinical trial is to learn if incorporating the structured care of a pet fish into a family-based diabetes self-care routine combined with communication skills training works to improve glycemic control, blood…
- Trial name
- NCT06598345
- Testing
- Routine Pet Fish Care, Collaborative Communication
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Type 1 Diabetes Mellitis, Cognition
Glycemic Control, Brain Structure and Cognition in Youth With Type 1 Diabetes (T1DM)
LO5 study: The investigators are inviting a new group of youth (ages 7-16) who have been recently diagnosed with type 1 diabetes and their non-diabetic siblings.
- Trial name
- LO5/HY5 (NCT00879203)
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Diabetes Mellitis Type 2
A Study to Characterize the Pharmacokinetics/Pharmacodynamics and Effect of Food of DA-1229 in Healthy Male Subjects
This is a dose block-randomized, double-blind, placebo-controlled, single/multiple dosing, dose-escalation study. The study is designed to describe the relationship between multiple doses and pharmacokinetic/pharmacodynamic…
- Trial name
- NCT00961025
- Testing
- DA-1229
- Where
- South Korea
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Dong-A Pharmaceutical Co., Ltd.
Type 1 Diabetes Mellitis
Diathermy On Diabetes Glucose Monitoring Effectiveness
The goal of this observational study is to investigate if diathermy (a surgical tool that uses electrical energy to control bleeding) has any affect on the accuracy and functioning of continuous glucose monitoring systems in…
- Trial name
- DODGE (NCT07583238)
- Where
- United Kingdom
- Volunteers
- 126 people
- Sponsor
- University of Nottingham
Type 1 Diabetes Mellitis
Neurocognitive Impact of Hypoglycemia in Type 1 Diabetes
125 children with Type 1 Diabetes mellitis (T1DM) between 4 and 16 were recruited and 62 healthy siblings also enrolled in the study.
- Trial name
- HYPO (NCT00916838)
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Type 1 Diabetes Mellitus, T1D
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
This study is a Phase 1b/2a First-in-Human (FIH) clinical trial to assess the safety, tolerability, pharmacodynamics (PD), and efficacy of multiple ascending doses of CNP-103.
- Conditions
- Type 1 Diabetes Mellitus, T1D, T1DM, T1DM - Type 1 Diabetes Mellitus
- Trial name
- NCT06783309
- Testing
- CNP-103
- Where
- 45 sites in United States
- Volunteers
- 72 people
- Sponsor
- COUR Pharmaceutical Development Company, Inc.
Type 1 Diabetes Mellitis
Evaluation of Insulin Glulisine (GP40321) Compared to Insulin Glulisine (Apidra® SoloStar®) in Type 1 Diabetes Mellitus Patients
The goal of this clinical trial is to demonstrate the non-inferior immunogenicity of GP40321 compared to Apidra® SoloStar® at a concentration of 100 U/mL in type 1 diabetes mellitus patients.
- Trial name
- NCT07070752
- Testing
- GP40321, Apidra® SoloStar®, RinGlar®
- Where
- 17 sites in Russia
- Volunteers
- 224 people
- Sponsor
- Geropharm
Type 1 Diabetes Mellitis
Clamp Study to Estimate the Relative Potency of GZR33 Versus Insulin Degludec at Steady State
This trial intends to investigate the pharmacodynamics, pharmacokinetics, safety, and tolerability of insulin GZR33 (hereafter referred to as GZR33) and estimate its potency in comparison with insulin degludec.
- Trial name
- NCT07242664
- Testing
- GZR-33
- Where
- 2 sites in Germany
- Volunteers
- 12 people
- Sponsor
- Gan and Lee Pharmaceuticals, USA
Type 1 Diabetes Mellitis, Celiac Disease
Metabolic Control and Glycemic Variability in Type 1 Diabetes and Celiac Disease
This is an observational, retrospective study focused on differences of time-in-range and glycemic variability between a cohort of patients with both type 1 diabetes and celiac disease, and a cohort of patients with only type 1…
- Trial name
- NCT06717841
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Type 1 Diabetes Mellitis
Effectiveness of Artificial-Intelligence (AI) Bolus Priming Added to an Existing Fully Automated Control Algorithm (AIDANET)
Bolus Priming (BP) based on Artificial Intelligence (AI) learning of meal patterns, added to our established Automated insulin delivery as Adaptive Network (AIDANET) algorithm and running on iPhone Diabetes Assistant (iDiAs)…
- Trial name
- AIDANET AI (NCT07517770)
- Testing
- Hybrid Closed Loop (HCL) x 2 weeks, AIDANET x 2 weeks, AIDANET AI x 4 weeks
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Sue Brown
Type 1 Diabetes Mellitis, Type 1 Diabetes (T1D)
Faecal Autologous Capsule Transplantation for Type 1 Diabetes Mellitus
SUMMARY Rationale: The(small) intestinal microbiota composition has been implicated to play an important role in (human) metabolism, as well as autoimmune diseases such as type 1 diabetes mellitus.
- Conditions
- Type 1 Diabetes Mellitis, Type 1 Diabetes (T1D), Fecal Microbiota Therapy (FMT)
- Trial name
- FACT-T1D (NCT07083882)
- Testing
- freezedried autologous encapsulated fecal microbiota transplantation
- Where
- Netherlands
- Volunteers
- 110 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)