Clinical trials: Twin Pregnancy With Antenatal Problem
Twin Pregnancy With Antenatal Problem
Vaginal Progesterone 400mg v.s 200mg for Prevention of Preterm Labor in Twin Pregnancies
It is already known that the risk of preterm labor in twin pregnancy before 37 week is 8-9 fold higher compared to singletons, and progesterone supplementation can decrease the incidence of preterm labor in singleton pregnancy.
- Trial name
- NCT04748562
- Testing
- Progesterone
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Preterm Birth, Twin Pregnancy With Antenatal Problem
Prophylactic Cerclage for Twin Pregnancy With Shortened Cervix
This randomized controlled trial is aimed to evaluate pregnancy and neonatal outcomes in twin pregnancies, in which a cervical cerclage is placed due to the shortening of the cervix with or without visible fetal membranes.
- Conditions
- Preterm Birth, Twin Pregnancy With Antenatal Problem, Cervical Shortening
- Trial name
- NCT05338164
- Testing
- cervical cerclage
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Twin Dichorionic Diamniotic Placenta, Twin Monochorionic Monoamniotic Placenta
Austrian Registry on the Outcome of Monochorionic Pregnancies
About one third of twin pregnancies are resulting from a single fertilized oocyte. Two third of these monozygotic twins share a common placenta and are therefore called monochorionic.
- Conditions
- Twin Dichorionic Diamniotic Placenta, Twin Monochorionic Monoamniotic Placenta, Twin-To-Twin Transfusion Syndrome, Twin Pregnancy With Antenatal Problem
- Trial name
- MonoReg (NCT03171909)
- Where
- 13 sites in Austria
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Twin Pregnancy With Antenatal Problem, Twin Diseases
Twin Pregnancy: a Challenge for Patients, Families and Health Professionals
Twin pregnancies represent 3-4% of all births and in the last two decades the rate of twin pregnancies has steadily increased, essentially due to the spread of assisted fertilization techniques, the use of drugs that stimulate…
- Conditions
- Twin Pregnancy With Antenatal Problem, Twin Diseases, Twin Placenta
- Trial name
- NCT05761769
- Testing
- no intervention
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Preterm Birth, Twin Pregnancy With Antenatal Problem
Progesterone and Cervical Pessary in Twins
The aim of this randomized control trial is to determine wheter cervical pessary plus vaginal progesterone (400mg) reduce preterm birth less than 34 weeks of gestacion and improve perinatal outcome, among women presenting…
- Trial name
- PRECEPET (NCT03058536)
- Testing
- Arabin Pessary, Vaginal Progesterone, Arabin Pessary and Progesterone
- Where
- Brazil
- Volunteers
- 312 people
- Sponsor
- Mario Henrique Burlacchini de Carvalho
Twin Pregnancy With Antenatal Problem
An Open Randomised Trial of the Arabin Pessary to Prevent Pre-term Birth in Twin Pregnancy
This study aims to determine whether the Arabin cervical pessary prevents preterm birth in women with a twin pregnancy and a short cervix.
- Trial name
- STOPPIT-2 (NCT02235181)
- Testing
- Arabin Cervical Pessary
- Where
- 57 sites in Belgium, United Kingdom
- Volunteers
- 2,228 people
- Sponsor
- University of Edinburgh
Prenatal Disorder, Premature Birth
Develop a Multi-disciplinary Approach for a Personalized Prenatal Diagnostics and Care for Twin Pregnancies
Different screening modalities evaluation to develop algorithms to predict pregnancy complications in twin pregnancies, and evaluation of serologic response to BNT162b2 Pfeizer/BioNTech vaccination.
- Conditions
- Prenatal Disorder, Premature Birth, Twin Pregnancy With Antenatal Problem, Twin; Pregnancy, Affecting Fetus or Newborn
- Trial name
- PRETWINSCREN (NCT04595214)
- Testing
- TTTS cases are treated by intra-uterine laser for separation.
- Where
- 7 sites in Belgium, Canada and 4 more
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Chromosome Abnormality, Twin Pregnancy With Antenatal Problem
Prenatal Screening, Diagnosis and Intrauterine Intervention of Fetal Abnormal Chromosome and Structure in Twins Pregnancy
The risk of abnormal chromosome and structure is much higher in twins than in singletons, and traditional early pregnancy screening strategy for single pregnancy is not suitable for twins.
- Trial name
- NCT02982356
- Testing
- Fetal Selective Reduction Technology, Potassium Chloride
- Volunteers
- 1,300 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Pregnant With Complication, Twin Pregnancy With Antenatal Problem
Twin Pregnancy Cohort
The investigators know that multiple factors are involved in the risk of obstetric complications. The twin pregnancy model appears to be an interesting model for a bio-statistical analysis of data collected in the context of a…
- Trial name
- COGEM (NCT05144321)
- Testing
- Impact of environment upon obstetrical, neonatal and maternal adverse outcome
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Twin Pregnancy With Antenatal Problem
Cerclage and Progesterone for Twin Pregnancies
Twin pregnancies face a high risk of complications, most notably preterm birth (delivery before 37 weeks), which is a major cause of infant death and illness globally.
- Trial name
- NCT07319715
- Testing
- McDonald Cervical Cerclage, Vaginal Progesterone Therapy (VPT)
- Where
- Egypt
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Benha University
Preterm Birth, Twin Pregnancy With Antenatal Problem
Emergency Cerclage in Twin Pregnancies at Imminent Risk of Preterm Birth: an Open-Label Randomised Controlled Trial
Twin pregnancies are at an increased risk of early delivery. One of the reasons for this may be due to a weakened neck of the womb (cervix). There are 2 main ways to manage a weakened cervix in pregnancy.
- Conditions
- Preterm Birth, Twin Pregnancy With Antenatal Problem, Twin to Twin Transfusion Syndrome
- Trial name
- ENCIRCLE (NCT03818867)
- Testing
- Insertion of cervical cerclage
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- St George's, University of London
Twin Pregnancy With Antenatal Problem
Diffusion Weighted Magnetic Resonance Imaging of Brain in Monochorionic Twin Pregnancies With Demise of One Fetus
Diffusion weighted imaging (DWI) can reflect the microstructure and pathological changes of tissue, and diffusion tensor imaging (DTI) can quantitatively evaluate the fine structure of white matter in brain.
- Trial name
- NCT04966039
- Testing
- No intervention.
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Twin Pregnancy With Antenatal Problem, Preterm Birth
Cerclage for Twins With Short Cervical Length ≤ 15mm
This is a multicenter randomized study designed to determine if ultrasound indicated cerclage reduces the incidence of spontaneous preterm birth <34 weeks in asymptomatic women with twin gestations and cervical length ≤15mm…
- Conditions
- Twin Pregnancy With Antenatal Problem, Preterm Birth, Short Cervix
- Trial name
- TWIN-UIC (NCT03340688)
- Testing
- Cervical cerclage
- Where
- 8 sites in United States, Egypt and 2 more
- Volunteers
- 200 people
- Sponsor
- Thomas Jefferson University
Twin Pregnancy With Antenatal Problem
External Cephalic Version (ECV) for Twins With Non-vertex Presenting Twin
In this study, women with a twin pregnancy with the presenting twin in a non-vertex(head) presenting twin undergo an external cephalic version.
- Trial name
- NCT05894785
- Testing
- External cephalic version
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Shaare Zedek Medical Center