Clinical trials: Turbinate
Chronic Sinusitis
Efficacy of ArchSinus, NasoPore & Propel to Prevent Post-Surgical MT Lateralization and Improve Symptomatic Outcomes
This is a multi-center, randomized, single-blinded comparative 3-arm clinical study. This clinical study is designed to compare the efficacy of the ArchSinus stent to the Propel stent (Intersect ENT), and to NasoPore (Stryker) in…
- Trial name
- NCT05156801
- Testing
- ArchSinus stent
- Volunteers
- 50 people
- Sponsor
- STS Medical
Nasal Polyps, Sinusitis
Study to Compare Resection Versus Preservation of the Middle Turbinate in Surgery for Nasal Polyps
Endoscopic sinus surgery (ESS) has become the standard of care for patients suffering of chronic rhinosinusitis with nasal polyposis (CRSwP) who have failed medical therapy.
- Trial name
- NCT02855931
- Testing
- Middle turbinate resection
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Nasal Surgery
Sterimar vs Saline Sprays in Nasal Surgical Aftercare - a Blinded, Randomised Trial
Patients undergoing nasal surgery commonly experience a variety of symptoms in the post-operative period including blockage, running, pain, bleeding and reduction in sense of smell.
- Trial name
- NCT00595608
- Testing
- Sterimar Spray, Generic homemade nasal saline spray (salt and water)
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- NHS Grampian
Nasal Septum; Deviation, Congenital
Prevalence of Variants of Nasal Cavity and Nasal Septum in Nepalese
A retrospective study was conducted on 343 patients. CT PNS and head of the patients were evaluated for variants of nasal septum and nasal cavity.
- Trial name
- NCT06434675
- Testing
- No intervention done
- Where
- Nepal
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Grande International Hospital, Nepal
Allergic Rhinitis
The Effect of Early Radiofrequency Turbinate Reduction on Persistent Allergic Rhinitis
The primary outcome of this study is to evaluate the effect of radiofrequency turbinate reduction as an initial treatment on clinical improvement (using visual analogue scale based on total nasal symptoms score, peak nasal…
- Trial name
- NCT05276336
- Testing
- Radiofrequency turbinate reduction, Pharmacology treatment
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Covid19
Optimal Length for Nasal Mid-turbinate and Nasopharyngeal Swabs
This study aim to explore the optimal swap insertion length for mid-turbinate and nasopharyngeal samples. Our clinical trial took place at a Covid-19 test center in Copenhagen.
- Trial name
- NCT04840082
- Testing
- Nasopharyngeal swab for COVID-19 testing
- Where
- Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sinus Disease, Rhinitis
Virtual Reality Induced Analgesia for Nasal Procedures
In-office nasal procedures can cause pain and discomfort to otolaryngology patients. While local anesthesia is the mainstay choice for main management, patients may have allergies or contraindications to the anesthetic agents…
- Conditions
- Sinus Disease, Rhinitis, Turbinate; Hypertrophy Mucous Membrane, Deviated Nasal Septum Acquired
- Trial name
- NCT06812676
- Testing
- Virtual Reality Goggles
- Where
- Saudi Arabia
- Volunteers
- 64 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Nasal Polyposis, Sinusitis
The Effect of RF Turbinoplasty in Polypoid Change of Middle Turbinates
The aim of this study is to evaluate the effect of middle turbinate Radio Frequency (RF) turbinoplasty with middle turbinate resection and medialization
- Trial name
- NCT01906697
- Testing
- middle turbinate Radio Frequency (RF) turbinoplasty, middle turbinate resection, middle turbinate medialization
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Tehran University of Medical Sciences
Sinus Endoscopic Surgery, Turbinate
Safety and Effectiveness of TurbAlign™ for Middle Turbinate Medialization After Functional Endoscopic Sinus Surgery
A study of a bioabsorbable implant to separate the middle turbinate from the lateral nasal wall associated with nasal/sinus surgery
- Trial name
- Gaia (NCT07027267)
- Testing
- Implantation of Spirair device into the middle turbinates, TurbAlign
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Spirair, Inc
COVID-19, Influenza A
Clinical Evaluation of the Panbio™ COVID-19/Flu A&B Rapid Panel Professional Use Product Using Mid-Turbinate Nasal Swabs
This study is designed as an international, prospective, multicentric, clinical study to investigate the performance of the Panbio™ COVID-19/Flu A\&B Rapid Panel for the qualitative detection of COVID-19 antigen, Influenza A…
- Conditions
- COVID-19, Influenza A, Influenza Type B
- Trial name
- NCT05630365
- Testing
- Panbio™
- Where
- United States
- Volunteers
- 1,129 people
- Sponsor
- Abbott Rapid Dx
Nasal Obstruction, Septal Deformity
Randomized Trial Comparing Partial Resection of Inferior Turbinate(PRIT) and Radiofrequency Ablation(RFA) for Inferior Turbinate Reduction
Turbinates are large structures in the nasal airway that help the nose to clean and humidify the air we breathe. Inferior turbinates can swell up and block the breathing passage, making it hard to breath.
- Conditions
- Nasal Obstruction, Septal Deformity, Turbinate Hypertrophy
- Trial name
- NCT00358267
- Testing
- Partial Resection of Inferior Turbinates (PRIT), Radiofrequency Ablation (RFA)
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Nasal Packing, Dexmedetomidine
Nasal Packing Versus Intravenous Dexmedetomidine in Turbinate Surgeries
Comparing of nasal packing DEX and IV DEX for controlling the intraoperative bleeding after turbinate surgery.
- Conditions
- Nasal Packing, Dexmedetomidine, Turbinate
- Trial name
- NCT05911776
- Testing
- Nasal packing Dexmedetomidine, Intravenous Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Inferior Turbinate Hypertrophy
Medial Flap Coblation Turbinoplasty Versus Submucous Resection
Both submucous resection and medial flap coblation turbinoplasty are equally effective and safe in relieving nasal obstruction and enabling optimal volume reduction with preservation of function of the inferior turbinate.
- Trial name
- NCT05738512
- Testing
- Medial Flap Coblation Turbinoplasty, Submucous Resection
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Sleep Apnea Syndromes, Nasal Obstruction
Randomized Clinical Trial of Nasal Turbinate Reduction to Improve Continuous Positive Airway Pressure (CPAP) Outcomes for Sleep Apnea
Obstructive sleep apnea occurs in 2-4% of middle age adults and results in significant morbidity and mortality. The first line therapy is provision of continuous positive airway pressure (CPAP) via a nasal mask chronically.
- Conditions
- Sleep Apnea Syndromes, Nasal Obstruction, Turbinate Hypertrophy
- Trial name
- TURBO (NCT00503802)
- Testing
- Radiofrequency Turbinate Reduction
- Where
- 3 sites in United States
- Volunteers
- 242 people
- Sponsor
- University of Washington
Allergic Rhinitis Due to House Dust Mite
Radiofrequency Ablation of Bilateral Inferior Turbinate Followed by Subcutaneous Immunotherapy Trial
Allergic rhinitis (AR) is a global health issue adversely impacting the quality of life (QoL) of affected individuals and exerting a huge public health burden.
- Trial name
- RABIT (NCT05510024)
- Testing
- Radiofrequency ablation of bilateral inferior turbinate followed by subcutaneous immunotherapy, SCIT
- Volunteers
- 392 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Inferior Nasal Turbinate Hypertrophy, Extraesophageal Reflux
Effect of Extraesophageal Reflux on Inferior Nasal Turbinates Hypertrophy
The study examines the severity of extraesophageal reflux using oropharyngeal pH monitoring in patients with varying degrees of lower turbinates hypertrophy.
- Trial name
- NCT04581174
- Testing
- 24-hour monitoring of oropharyngeal pH by Restech, RYAN scores upright and supine, and pH values <5.5 will be evaluated
- Where
- 3 sites in Czechia, Slovakia
- Volunteers
- 160 people
- Sponsor
- University Hospital Ostrava
Chronic Rhinosinusitis
Computed Tomography (CT) Score and Histopathology of the Middle Turbinate in Chronic Rhinosinusitis
In a previous study (Berger el al. Old and new aspects of middle turbinate histopathology. Otolaryngol Head Neck Surg. 2009;140:48-54), the investigators reported significant histopathologic changes in the middle turbinate mucosa…
- Trial name
- CT (NCT00899561)
- Where
- 2 sites in Israel
- Volunteers
- 45 people
- Sponsor
- Meir Medical Center
Sinusitis
Evaluation of the Middle Turbinate Implant for Affixing the Middle Turbinate to the Nasal Septum
The purpose of this study is to determine the functional performance of the Middle Turbinate Implant (MTI). The MTI will be used in all patients requiring endoscopic sinus surgery in which the Principal Investigator determines…
- Trial name
- MTI (NCT00896883)
- Testing
- Middle Turbinate Implant
- Where
- 4 sites in United States
- Volunteers
- 18 people
- Sponsor
- ENTrigue Surgical, Inc.
Sinusitis, Sinusitis Bacterial
Best Practice in the Management of Concha Bullosa in FESS Operation
Concha bullosa (CB) refers to the condition where the middle turbinate's interior is aerated (making the turbinate wide and thick). CB can narrow the middle meatus and the ostiomeatal complex.
- Conditions
- Sinusitis, Sinusitis Bacterial, Sinusitis Recurrent, Turbinate; Hypertrophy Mucous Membrane
- Trial name
- NCT06687629
- Testing
- Concha bullosa crushing, Concha bullosa resection
- Where
- Finland
- Volunteers
- 62 people
- Sponsor
- Helsinki University Central Hospital
Sleep Related Breathing Disorder, Upper Airway Resistance Syndrome
Inferior Turbinate Reduction in Pediatric Population Failing Surgery for Sleep Disordered Breathing
This study will examine whether treatment of inferior turbinates in patients with continued symptoms of obstructive sleep apnea, sleep related breathing disorder, snoring, disturbed sleeping, open mouth breathing, and upper…
- Conditions
- Sleep Related Breathing Disorder, Upper Airway Resistance Syndrome, Obstructive Sleep Apnea
- Trial name
- NCT00936494
- Testing
- Cold ablation inferior turbinate reduction
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia