Clinical trials: Tumor of the Sellar Region
Pituitary Adenoma, Visual Impairment
Clinical Study of Structural and Functional Evaluation of the Visual Pathway
Sellar area tumors such as pituitary adenoma, craniopharyngioma and meningioma, etc, commonly lead to visual impairment symptoms.
- Conditions
- Pituitary Adenoma, Visual Impairment, Sellar Tumor, Neuroimaging
- Trial name
- NCT03591315
- Testing
- resting state fMRI, visual tasking state fMRI, diffusion tensor imaging
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Glioma, Glioneuronal Tumor
Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification
Every new classification depends on its prognostic power and on the type of treatment given. With the rapid evolution of diagnostic methods and the advance in new treatments, there is much less reliable information available on…
- Conditions
- Glioma, Glioneuronal Tumor, Choroid Plexus Tumor, Pineal Tumors
- Trial name
- NCT05259605
- Testing
- Observational
- Where
- 42 sites in Austria, Belgium and 10 more
- Volunteers
- 1,650 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Cystic Tumors of the Sellar/Parasellar Region
90Yttrium Colloid for the Treatment of Cystic Sellar/Parasellar Tumors
There is no consensus in the literature on the best way to treat cystic lesions of the pituitary area. Patients who are symptomatic from these tumours are rare.
- Trial name
- NCT02081768
- Testing
- 90yttrium colloid
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- David Clarke
Craniopharyngiomas, Pituitary Macroadenoma
Randomized Controlled Clinical Study on the Prophylactic Intraoperative Use of Desmopressin in Complex Sellar Region Tumors
Craniopharyngiomas and giant invasive pituitary adenomas, with lesions originating from the pituitary stalk, are frequently associated with intraoperative and postoperative diabetes insipidus (DI).
- Conditions
- Craniopharyngiomas, Pituitary Macroadenoma, Sellar and Suprasellar Masses
- Trial name
- RCT-PIDST (NCT07712328)
- Testing
- Desmopressin (DDAVP), Control
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Zhaoyun Zhang
Cavernous Sinus Meningioma, Pituitary Adenoma
Effect of Irradiation of the Cavernous Sinus and the Sellar Region on Autobiographical Memory
Several studies showed that radiotherapy as brain tumors treatment may affect cognition. It was observed that durable memory impairments could arise at irradiated patients if radiotherapy is applied on medial temporal lobes.
- Trial name
- ISOMAB (NCT02750371)
- Testing
- Evaluation of autobiographical memory
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Bordeaux
Csf Leakage
Chitosan Scaffold for Sellar Floor Repair in Endoscopic Endonasal Transsphenoidal Surgery
A 65 year old female participant , right handed, started with progressive bilateral visual loss in her temporal field, over 10 months, the participant underwent an MRI and it was found a sellar lesion that compressed the optic…
- Trial name
- NCT03280849
- Testing
- Implant of bilaminar chitosan scaffold
- Where
- Mexico
- Volunteers
- 1 people
- Sponsor
- University of Guadalajara
Sellar Tumor, Endonasal Surgery
Efficacy and Safety Evaluation of Absorbable and Moldable Skull Base Support Plates in Extended Endoscopic Endonasal Transsphenoidal Surgery: A Prospective, Randomized, Controlled Study
Primary objective: To evaluate the effect of absorbable and moldable skull base support plates used in extended endoscopic endonasal transsphenoidal surgery on the incidence of cerebrospinal fluid (CSF) rhinorrhea within 1 month…
- Conditions
- Sellar Tumor, Endonasal Surgery, Csf Leakage
- Trial name
- EEEA-AMSBP (NCT07539792)
- Testing
- Absorbable and moldable skull base support plate
- Where
- 8 sites in China
- Volunteers
- 126 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Optic Nerve Injuries, Sellar Tumor
Optic Nerve Stimulation To Prevent Visual Deficits After Endoscopic Cranial Approaches
Assessing the function of the optic nerve is paramount during various neurosurgical procedures. Effective optic nerve monitoring has remained elusive as Visual Evoked Potentials (the current existing tool) provides only diffuse…
- Conditions
- Optic Nerve Injuries, Sellar Tumor, Skull Base Neoplasms
- Trial name
- NCT06495580
- Testing
- Optic Nerve Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco