Clinical trials: Triglycerides
Bariatric Surgery
Fat Absorption and Metabolism After Roux-en-Y Gastric Bypass
Using intravenous and oral administration of stable isotope tracers, we will investigate the importance of altered fat absorption and altered whole body fat metabolism for the reduced postprandial systemic TAG concentrations in…
- Trial name
- FAT-BAR (NCT04859816)
- Testing
- Metabolic test, DXA-scan, MRS
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Waist, Hypertriglyceridemic
Dietary Incorporation of Lentils to Improve Metabolic Health
Approximately 40% of Americans are pre-diabetic or diabetic, mostly in the form of type 2 diabetes (T2D), which is heavily influenced by diet.
- Trial name
- NCT04448067
- Testing
- Dietary Lentil Intake, No Dietary Lentil CONTROL
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Montana State University
Metabolic Disease
Butyrate/Hexanoate in Metabolic Health
In this study, we aim to identify a well consumable butyrate/hexanoate-enriched oil that increases circulating SCFA concentrations and improves postprandial substrate metabolism, which could be further used for a long-term study.
- Trial name
- NCT04662411
- Testing
- butyrate and hexanoate amount 1, butyrate and hexanoate amount 2, butyrate and hexanoate amount 3
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity
The Effect of Rimonabant on Energy Expenditure, Fat Metabolism and Body Composition
This study will determine in obese subjects the direct effects of the weight loss drug rimonabant (ie independent of weight loss) on energy expenditure, fat metabolism and and body fat distribution.
- Trial name
- NCT00584389
- Testing
- rimonabant, Dietary intervention
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Obesity, Type 2 Diabetes
Role of Pancreatic Triglyceride Content in Beta-cell Function
The study evaluates if fat accumulates in the pancreas in individuals at risk of developing obesity-related diabetes. It also evaluates if the amount of fat in the pancreas can predict the residual functional capacity of the…
- Trial name
- NCT00602953
- Testing
- No intervention planned.
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Healthy
Study to Investigate the Effects of Krill Oil on Fasting Serum Triglycerides
The purpose of this study is to assess the effect of 12 weeks of daily supplementation with Superba(TM) Krill Oil on fasting serum triglyceride levels and omega-3 index in subjects whose habitual fatty fish and seafood intake is…
- Trial name
- NCT01415388
- Testing
- Krill Oil
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aker BioMarine Human Ingredients AS
Obesity
Maximal Fat Oxidation and Fuel Use During Exercise
Fat and carbohydrate are the two main energy stores available as fuel during exercise. It is well known that the exercise intensity and feeding status are the major factors determining the type of fuel used during exercise.
- Trial name
- NCT04678713
- Testing
- investigate the nutritional determinants of MFO in moderate to well-train individuals, Investigate the physiological determinants of MFO in moderate to well-train individuals
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dry Eye
Effect of Re-esterified Triglyceride (rTG) Form Omega-3 Supplements on Dry Eye Following Cataract Surgery
To evaluate the clinical outcomes of the systemic re-esterified triglyceride (rTG) form of omega-3 fatty acids in patients with dry eye symptoms after cataract surgery
- Trial name
- NCT04411615
- Testing
- Omega 3
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Healthy Adults
Comparative Study of Three Different Formulations of Omega-3 (EPA+DHA)
This pilot study aims at comparing the bioavailability of three different formulations of the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).
- Trial name
- NCT04159532
- Testing
- MAG-EPA/MAG-DHA, TG-EPA/TG-DHA, EE-EPA/EE-DHA
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- SCF Pharma
Carnitine Transporter Deficiency
Influence of OCTN2 Variants on Carnitine Status and Plasma Triglycerides
The current study is part of a large multi-investigator grant to look at the pharmacogenetics of a number of membrane transporters.
- Trial name
- NCT00187733
- Testing
- Fasting blood and urine collection
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Blood Glucose
The Effects of L-arabinose on Intestinal Sucrase Activity in Man
The purpose of this study is to investigate the effect of L-arabinose in a sugar-rich meal on intestinal sucrase activity in healthy volunteers by measuring postprandial blood glucose and insulin, and selected intestinal hormonal…
- Trial name
- NCT00302302
- Testing
- L-arabinose
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy
Multi-country Study- Effect of Dietary Fats on Fat Deposition
There is existing evidence to show that vegetable oils having unsaturated fatty acids in the sn-2 position with predominantly palmitic acid (C16:0) or stearic acid (C18:0) in the sn-1 and sn-3 positions of fat molecules do not…
- Trial name
- NCT02797483
- Testing
- Test Fat Blue, Test Fat Green, Test Fat Red
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Dyslipidemia, Diabetes
Meta-analyses of Fructose and Cardiometabolic Risk
Diabetes and heart associations continue to discourage high intakes of dietary fructose, a constituent part of the sucrose molecule that is found in fruits and vegetables as a natural sugar and in some processed foods and…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT01363791
- Testing
- Dietary fructose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Hyperlipidemias, Hypertension
The Effect of Farlong® NotoGinseng™ (Ginseng Plus®) on Cholesterol and Blood Pressure
In this randomized, placebo-controlled, double-blind parallel study in human participants with elevated LDL-C and elevated BP described here, the clinical benefits of Farlong NotoGinseng™ (Farlong Ginseng Plus® Panax Notoginseng…
- Trial name
- NCT04069715
- Testing
- Farlong NotoGinseng™ (Farlong Ginseng Plus® Panax Notoginseng extract)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- LongStar HealthPro, Inc. DBA Farlong Pharmaceutical
Insulin Resistance
Use of Novel High-protein Food Products To Reduce Insulin Resistance
This controlled weight loss trial in adults at cardiometabolic risk (elevated triglyceride/HDL ratio) followed a randomized, cross-over design and utilized novel, high-protein pasta and cereal to examine the physiological impact…
- Trial name
- NCT02851498
- Testing
- Food product: high-protein pasta and cereal
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Healthy Subjects, Bioavailability
Bioavailability of Oleanolic Acid Formulated as Functional Olive Oil
The oral bioavailability of Oleanolic acid (OA) when formulated as functional olive oil, and its mechanisms of systemic transport, will be approached by mean of randomized and controlled trial with 20 healthy volunteers.
- Trial name
- BIO-OLTRAD (NCT05529953)
- Testing
- Oleanolic acid (CAS no. 598-02-1; PubChem CID 10494), Control commercial olive oil
- Where
- Spain
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Spanish National Research Council
NAFLD
Understanding the Role of Dietary Fatty Acids on Liver Fat Metabolism in Humans
High levels of fatty substances in the blood increase the risk of developing heart disease. Investigators know a lot about one of these fatty substances, cholesterol.
- Trial name
- NCT01936779
- Testing
- Dietary supplement: fatty acid
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Hyperlipidemia
A Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Effects of JS401
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetcs and pharmacodynamics of single-dose of JS401 in healthy volunteers with normal or mildly elevated triglycerides.
- Trial name
- NCT06041165
- Testing
- JS401
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Shanghai Junshi Bioscience Co., Ltd.
Healthy Men, Raised Fasting Plasma Triacylglycerol Concentrations
Palmitic Acid in the Sn-2 Position of Triacylglycerols and Postprandial Lipemia
The purpose of this study is to determine whether high-fat meals rich in palmitic acid in the sn-2 position decrease lipaemia in men aged 40-70 y with higher than optimal fasting triacylglycerol concentrations.
- Trial name
- NCT01710280
- Testing
- High-fat meal containing native palm olein, High-fat meal containing interesterified palm olein
- Where
- United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- King's College London
Triglyceride Metabolism, Cardiovascular Function
Ability of Grape Seed Proanthocyanidins to Reduce Postprandial Triglycerides in Humans
Grape seed proanthocyanidins have been reported to possess a hypotriglyceridemic effect after an acute or chronic consumption in rodents.
- Trial name
- NCT01688154
- Testing
- 35 mg/Kg of grape seed proanthocyanidins extract (2 capsules), 2 empty capsules
- Where
- 2 sites in Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Technological Centre of Nutrition and Health, Spain