Clinical trials: Trichiasis
Trachoma, Eye Diseases
RESTORE: Comparing Two Approaches to Repeat TT Surgery Performed by Integrated Eye Care Workers (IECWs)
The primary objective of this randomized clinical trial is to determine whether repeat trichiasis surgery performed with Bevel-Rotate Advancement Procedure (B-RAP) improves surgical success compared to Bilamellar Tarsal Rotation…
- Conditions
- Trachoma, Eye Diseases, Trichiasis
- Trial name
- NCT07322302
- Testing
- B-RAP, BLTR
- Where
- 2 sites in United States, Tanzania
- Volunteers
- 1,000 people
- Sponsor
- University of North Carolina, Chapel Hill
Trachomatous Trichiasis (TT), Eye Diseases
FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial
This study aims : To assess the efficacy of fluorometholone 0.1% one drop twice daily for four weeks in reducing the incidence of post-operative trachomatous trichiasis (TT) when given as adjunctive therapy with TT surgery in the…
- Conditions
- Trachomatous Trichiasis (TT), Eye Diseases, Eyelid Diseases, Trachomatous
- Trial name
- FLAME (NCT04149210)
- Testing
- Fluorometholone 0.1% Oph Susp, Artificial Tears
- Where
- Ethiopia
- Volunteers
- 2,410 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Trichiasis, Surgery
Repeat Surgery for Patients With Post-operative Trachomatous Trichiasis Trial
The objective of this study is to determine if there is a significant difference in post-operative trichiasis at 12 months comparing a new procedure, the Bevel/rotate/advance procedure (BRAP), to the Trabut procedure among repeat…
- Trial name
- PTT (NCT03886519)
- Testing
- BRAP (Bevel/rotate/advance procedure), Trabut
- Where
- Ethiopia
- Volunteers
- 886 people
- Sponsor
- University of North Carolina, Chapel Hill
Trichiasis, Surgery
Maximizing Trichiasis Surgery Success
The purpose of this study is to determine whether the rate of post-operative trachomatous trichiasis differs significantly between bilamellar tarsal rotation surgery with an incision height of 3 mm, bilamellar tarsal rotation…
- Trial name
- MTSS (NCT03100747)
- Testing
- Bilamellar 3 mm, Bilamellar 5 mm, Trabut 3 mm
- Where
- Ethiopia
- Volunteers
- 4,914 people
- Sponsor
- University of North Carolina, Chapel Hill
Trichiasis
Histology Evaluation of Radiofrequency Ablation
Trichiasis is a disorder of misdirected eyelashes in which the lashes grow inward towards the eye. Trichiasis can occur as a result of chronic inflammation, infection, such as in herpes or trachoma, trauma, or rare diseases like…
- Trial name
- NCT03947723
- Testing
- Radiofrequency ablation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ochsner Health System
Cicatricial Trichiasis
Anterior Lamellar Recession vs Bilamellar Tarsal Rotation in Upper Lid Cicatricial Trichiasis
in recent years there has been a significant shift from this destructive procedure to a reconstructive procedure such as Anterior Lamellar Recession (ALR) and Bilamellar Tarsal Rotation (BLTR).
- Trial name
- NCT05634629
- Testing
- Anterior Lamellar Recession, Bilamellar Tarsal Rotation
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Al-Azhar University
Trichiasis
Identification of TT Cases by Community Treatment Assistants: An Assessment
To achieve the goal of trachoma control as mandated by the World Health Organization, countries must reduce the backlog of trichiasis surgery cases to less than 1/1,000 of their population.
- Trial name
- SIMBA (NCT01783743)
- Testing
- TT Training Program and TT Screening Card
- Where
- United States
- Volunteers
- 27,473 people
- Sponsor
- Johns Hopkins University
Trichiasis, Surgery
The Effect of Long-Term HEAD START Training on Surgical Skill Levels
The research group developed a surgical simulation device, the Human Eyelid Analogue Device for Surgical Training And skill Reinforcement in Trachoma (HEAD START), to bridge the gap between classroom and live-surgery training…
- Trial name
- NCT03135080
- Testing
- Long-Term HEAD START Training, Standard of Care
- Where
- 3 sites in Ethiopia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Trichiasis
Study of Azithromycin to Prevent Recurrent Trichiasis Following Surgery in Ethiopia
Trachoma, an ocular infection caused by C. trachomatis, is the second leading cause of blindness worldwide.Years of repeated infection with C.
- Trial name
- STAR (NCT00347776)
- Testing
- azithromycin, topical tetracycline
- Where
- United States
- Volunteers
- 1,452 people
- Sponsor
- Johns Hopkins University
Trachoma
Modified Instrumentation for Surgery to Correct Trichiasis
Trachoma, an ocular infection caused by C. trachomatis, is the second leading infectious cause of blindness worldwide. Years of repeated infection with C.
- Trial name
- NCT00886015
- Testing
- TT Clamp, Standard BLTR Technique
- Where
- United States
- Volunteers
- 1,927 people
- Sponsor
- Johns Hopkins University
Trichiasis, Trachoma
Fluorometholone as Ancillary Therapy for TT Surgery
The investigators aim to evaluate a new potentially cost-effective approach to improving trichiasis surgery outcomes, perioperative topical anti-inflammatory therapy.
- Conditions
- Trichiasis, Trachoma, Bilamellar Tarsal Rotation
- Trial name
- NCT01949454
- Testing
- Fluorometholone 0.1% ophthalmic solution
- Where
- Ethiopia
- Volunteers
- 154 people
- Sponsor
- University of Pennsylvania
Trachomatous Trichiasis, Trachoma
A Trial of Non-absorbable Versus Absorbable Sutures for Trichiasis Surgery
Trachoma is the leading infectious cause of blindness worldwide. Recurrent infection by Chlamydia trachomatis causes in-turning of the eyelids / lashes (trichiasis), leading to corneal damage and blindness.
- Trial name
- NCT00522860
- Testing
- Trichiasis surgery with absorbable sutures, Trichiasis surgery with non-absorbable sutures
- Where
- Ethiopia
- Volunteers
- 1,300 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Trachomatous Trichiasis
A Trial of Epilation Verses Surgery for Minor Trichiasis
Trachoma is the leading infectious cause of blindness worldwide. Recurrent infection by Chlamydia trachomatis causes a gradual scarring process of the inner surface of the eyelid (conjunctiva) leading to in-turning of the eyelids…
- Trial name
- NCT00522912
- Testing
- Trichiasis surgery, Epilation
- Where
- Ethiopia
- Volunteers
- 1,300 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Trichiasis
Comparison of Argon Laser and Radiofrequency in Trichiasis Treatment
In this clinical trial study,the investigators intend to compare two methods of trichiasis treatment.One by argon laser and the other by radiofrequency then compare the result of these procedures, especially, the investigators…
- Trial name
- NCT00776269
- Testing
- argon laser and radiofrequency
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences