Clinical trials: Traumatic Disorder
Brain Injury, Coma
Brain Death and Organ Donation in Tunisian Intensive Care Units
The goal of this observational study was to identify factors associated with the progression to brain death in critically ill patients with severe brain injuries in Tunisian intensive care units (ICUs).
- Conditions
- Brain Injury, Coma, Organ Transplants
- Trial name
- BDOD-TN (NCT06948669)
- Where
- Tunisia
- Volunteers
- 104 people
- Sponsor
- Faculty of Medicine, Sousse
Urinary Tract Infection, Head Injury
Video Discharge Instructions (VDI) as Adjuncts to Written Discharge Instructions in the Emergency Department
Patients seen in the ED with either a laceration, minor head injury, or urinary tract infection will be randomized to one of two groups.
- Conditions
- Urinary Tract Infection, Head Injury, Laceration
- Trial name
- NCT02882256
- Testing
- Video discharge instructions
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- George Washington University
Spinal Cord Injuries and Disorders (SCI/D), Spinal Cord Injury
Motoneuron Recruitment and Motor Evoked Potential Up-Conditioning (MEP) in Spinal Cord Injury (SCI)
The purpose of this research study is to examine the effect of a brain stimulation training to improve the function of brain-spinal cord- muscle connections.
- Trial name
- NCT07179822
- Testing
- Motor Evoked Potential (MEP) Operant Conditioning
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medical University of South Carolina
Spinal Cord Injury
Autologous Mesenchymal Stem Cells Transplantation in Cervical Chronic and Complete Spinal Cord Injury
The purpose of this study is to analyze the safety and efficacy of autologous bone marrow mesenchymal stem cell transplantation in patients with cervical chronic and complete spinal cord injury.
- Trial name
- NCT02574572
- Testing
- Autologous mesenchymal cells transplantation
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Hospital Sao Rafael
Peripheral Nerve Injuries
Chronic Neuropathic Pain After Nerve Repair Hand Surgery
This study intends to compare the patients with pain with those who underwent same procedure without developing pain. The patients with pain and without pain will be further analyzed in respect to clinical differences, biomarkers…
- Trial name
- NCT03174665
- Testing
- No intervention
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Traumatic Brain Injury, Subarachnoid Hemorrhage
Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention
To show that the use of intravenous levetiracetam(LEV;Keppra)for seizure prevention in patients in the Neuroscience Intensive Care Unit will result in fewer side effects compared to the current standard of care anticonvulsant and…
- Trial name
- Keppra (NCT00618436)
- Testing
- Levetiracetam, Phenytoin
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Cincinnati
Concussion, Brain, Mild Traumatic Brain Injury
Risk Stratification in Children With Concussion
This project will measure concussion symptoms, biological markers, and academic and social factors across the first year postconcussion to develop a model that enables early identification of and symptom management for children…
- Trial name
- RSiCC (NCT05825027)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Duke University
Post-Traumatic Headache
Hypersensitivity to PACAP-38 in Post-Traumatic Headache
The aim is to investigate whether signaling molecule PACAP-38 induces headache with migraine-like features in people with persistent post-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI).
- Trial name
- NCT05378061
- Testing
- Pituitary adenylate cyclase activating polypeptide-38
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Danish Headache Center
Carpal Tunnel Syndrome
The Effect of Perineural Injection Therapy in Patients With Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT02809261
- Testing
- Ultrasound-guided perineural injection with 5% dextrose, Ultrasound-guided perineural injection with normal saline, Normal Saline
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Carpal Tunnel Syndrome, Dupuytren Contracture
Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery
This study is about pain control and medication following outpatient soft-tissue hand surgery. We hope to learn if ibuprofen and acetaminophen will achieve similar pain relief and satisfaction when compared with oxycodone alone.
- Conditions
- Carpal Tunnel Syndrome, Dupuytren Contracture, Trigger Digit, Ganglion Cysts
- Trial name
- NCT03111186
- Testing
- Oxycodone Hcl 5Mg, Ibuprofen 400 mg, Acetaminophen 650 mg
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Southern California
Concussion, Brain
The TRAIN Study: A Concussion Prevention Strategy in Middle Schools
Purpose: The purpose of this study is to evaluate the effectiveness of a theory-driven intervention (TRAIN concussion education) to improve parental concussion-related attitudes, beliefs, intentions, confidence in knowledge, and…
- Trial name
- NCT04841473
- Testing
- TRAIN Concussion Education, Standard Concussion Education
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cervical Carcinoma, Human Papillomavirus Infection
Evaluating the Human Papillomavirus Self-Collection Experience in Individuals Who Have Experienced Sexual Trauma
This study explores the human papillomavirus (HPV) self-collection experience among individuals with a history of sexual trauma.
- Trial name
- NCT05458869
- Testing
- HPV Self-Collection, Interview, Survey Administration
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Carpal Tunnel Syndrome
Corticosteroid and Repeated Dextrose Hydro-dissection for Carpal Tunnel Syndrome Patients
Carpal tunnel syndrome (CTS) is the most prevalent peripheral nerve entrapment of upper limb. Typical symptoms comprise pain, numbness or tingling of the thumb and index, middle or ring fingers.
- Trial name
- NCT04579783
- Testing
- Triamcinolone Acetonide, Dextrose 5% in water
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Moral Injury
Moral Injury Study Among Healthcare Professionals in Psychiatric Facilities in the PACA Region
Healthcare professionals working in psychiatric settings face demanding working conditions characterized by high rates of burnout and specific constraints, such as the deprivation of patients' liberty.
- Trial name
- MI-PSY (NCT07631741)
- Testing
- Self-Questionnaires for Healthcare Workers
- Where
- France
- Volunteers
- 2,688 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Spinal Cord Injury
Autologous Mesenchymal Stem Cells Transplantation for Spinal Cord Injury- A Phase I Clinical Study
The conventional treatment of spinal cord injury (SCI) includes physical therapy and rehabilitation and in some cases may require surgical intervention.
- Trial name
- NCT02482194
- Testing
- mesenchymal stem cells
- Where
- Pakistan
- Volunteers
- 9 people
- Sponsor
- National Institute of Blood and Marrow Transplant (NIBMT), Pakistan
Spinal Cord Injury, Acute
Investigating the Energy Expenditure of Acute Spinal Cord Injured Patients
It is recognised that weight gain is a common problem in patients with a spinal cord injury and can lead to an increased incidence of metabolic syndrome.
- Trial name
- NCT03661294
- Testing
- GE Healthcare Metabolic Oxygenator
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Traumatic Brain Injury
Evaluation and Diagnosis of Potential Research Subjects With Traumatic Brain Injury
Background: The Center for Neuroscience and Regenerative Medicine is working to improve physicians' understanding of brain injury.
- Trial name
- NCT01287156
- Where
- 4 sites in United States
- Volunteers
- 1,328 people
- Sponsor
- National Institute of Nursing Research (NINR)
Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD)
Study of Emotional Dysregulation in Complex Post-Traumatic Stress Disorder
This study aims to characterize emotional dysregulation in complex post-traumatic stress disorder (cPTSD) and to determine the extent to which it can promote the distinction with borderline personality disorder (BPD) and…
- Conditions
- Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD), Post-traumatic Stress Disorder (PTSD)
- Trial name
- TR-EMA (NCT06848127)
- Testing
- Self-questionnaires, Cognitive assessment, Momentary Ecological Assessment (EMA)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Cognitive Rehabilitation, Brain Injuries
Hypnosis in Working Memory Rehabilitation
Establishment of effective, efficient, and evidence-based interventions in rehabilitation of working memory (WM) deficits after acquired brain injury (ABI) is sorely needed.
- Conditions
- Cognitive Rehabilitation, Brain Injuries, Cognitive Impairment, Working Memory
- Trial name
- NCT05287542
- Testing
- Hypnotic suggestion, Mindfulness
- Where
- Norway
- Volunteers
- 90 people
- Sponsor
- Sunnaas Rehabilitation Hospital
PTSD
Open Label Study of MDMA-assisted Psychotherapy for Treatment of PTSD With Optional fMRI Sub-Study
The goal of this clinical trial is to learn if MDMA-assisted therapy is safe and effective in people diagnosed with at least severe PTSD.
- Trial name
- NCT04030169
- Testing
- Midomafetamine HCl
- Where
- 6 sites in Czechia, Germany and 3 more
- Volunteers
- 21 people
- Sponsor
- MAPS Europe B.V.