Clinical trials: Trauma/Injury Problem, active
Trauma Injury
Retrospective Assessment of Referral of a Major Trauma Patient
The aim of this study is to find out whether major trauma patients from the Val d'Oise are referred to the appropriate trauma centre for their care and to assess the quality of triage within the Val d'Oise department.
- Trial name
- SAMU-TRAUMAS (NCT06551350)
- Testing
- Data Collection
- Where
- France
- Volunteers
- 461 people
- Sponsor
- Hôpital NOVO
Sepsis, Trauma Injury
Microbiome Dysfunction in Surgical Intensive Care Unit Survivors
Oral and gastrointestinal microbiome dysfunction has been demonstrated to be a culprit of various systemic dysfunctions in peripheries such as cardiovascular, nervous, endocrine and musculoskeletal systems.
- Trial name
- NCT05357170
- Testing
- Human feces collection
- Where
- United States
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- University of Florida
PTSD, Alcohol; Use, Problem
Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma
The U.S. Deaf community - a group of more than one million Americans who communicate using American Sign Language (ASL) - experiences nearly triple the rate of lifetime problem drinking and twice the rate of trauma exposure…
- Trial name
- NCT06278922
- Testing
- Seeking Safety + Signs of Safety toolkit, Treatment as usual
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Massachusetts, Worcester
Renal Disease, Liver Diseases
Outcomes of Children After Hospitalization in Intensive Care Unit
More than 10,000 children are hospitalized in an PICU every year in Canada. While most of them will survive their PICU hospitalization and their critical illness, some children will not recover to their pre-illness level.
- Conditions
- Renal Disease, Liver Diseases, Heart Diseases, Trauma Injury
- Trial name
- APCI (NCT06124092)
- Testing
- neurocognitive tests
- Where
- 8 sites in Canada
- Volunteers
- 690 people
- Sponsor
- St. Justine's Hospital
Trauma (Including Fractures), Trauma ICU Patients
Mortality of Trauma in the Intensive Care Unit.
In this study, it was planned to establish the factors associated with severe trauma discharged from the intensive care unit and mortality.
- Conditions
- Trauma (Including Fractures), Trauma ICU Patients, Trauma Injury, Trauma Patients in ICU
- Trial name
- MOTRAM-ICU-COL (NCT07208110)
- Testing
- Exposed to trauma, Not exposed
- Where
- Colombia
- Volunteers
- 500 people
- Sponsor
- Hospital Departamental de Villavicencio
Psychiatric Problem, Child Neglect
Implementing Dyadic Developmental Psychotherapy (DDP) - Evaluation Research
The objective of this study is to evaluate the implementation and use of Dyadic Developmental Psychotherapy (DDP) in three centra, with particular focus on its potential effects on the quality of the observable caregiver-child…
- Conditions
- Psychiatric Problem, Child Neglect, Maltreatment, Child Behavior Problem
- Trial name
- NCT04763720
- Testing
- Dyadic Developmental Psychotherapy
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Sykehuset Telemark
Brain Injuries, Traumatic, Wounds and Injury
Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children: An Efficacy Study
Trauma is the leading cause of death and disability in children in the United States. The objective of this study is to evaluate the benefits and harms of tranexamic acid (TXA; a drug that stops bleeding) in severely injured…
- Conditions
- Brain Injuries, Traumatic, Wounds and Injury, Hemorrhage, Trauma Injury
- Trial name
- TIC-TOC (NCT04387305)
- Testing
- Tranexamic acid injection
- Volunteers
- 2,000 people
- Sponsor
- Daniel Nishijima, MD, MAS
Trauma Injury, Trauma, Multiple
Effectiveness of a Self-management Program After Traumatic Injury
Traumatic injuries, defined as a physical injury with sudden onset, are a leading cause to disability and impaired health. Persons who sustain a traumatic injury often report problems in daily life activities and reduced quality…
- Conditions
- Trauma Injury, Trauma, Multiple, Polytrauma
- Trial name
- SEMPO (NCT06305819)
- Testing
- self-management support program, Control group
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- Oslo University Hospital
Sepsis, Trauma Injury
Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis
Adverse outcomes in surgical sepsis patients are secondary to dysregulated emergency myelopoiesis, and expansion of myeloid-derived suppressor cells.
- Trial name
- NCT05110937
- Testing
- Blood sampling
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Florida
Trauma Injury
Reducing Low-value Care for Trauma Admissions
In Canada, injury leads to more potential years of life lost and to greater costs than heart and stroke diseases combined. Furthermore, more than 50% of patients hospitalised following injury do not receive optimal care, 20% of…
- Trial name
- NCT05744154
- Testing
- Audit & feedback with educational outreach and facilitation, Simple audit & feedback (usual practice)
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- Laval University
Psychological Distress, PTSD
Boosting Refugee Integration Through Psychological Intervention
Refugees and asylum seekers (RAS) face numerous stressors and adversities which put them at risk for developing mental health problems. However, access to adequate mental health care in host countries is limited.
- Conditions
- Psychological Distress, PTSD, Trauma, Common Mental Health Problems
- Trial name
- BRIGHT (NCT06776523)
- Testing
- Problem Management Plus
- Where
- Switzerland
- Volunteers
- 1,200 people
- Sponsor
- University of Zurich
Trauma Injury, Modified Trauma Scoring Systems
FOUR Score-Modified Trauma Scores for Mortality Prediction
The goal of this multicenter prospective observational cohort study is to develop and validate FOUR Score-modified trauma scoring systems for mortality prediction in adult trauma patients.
- Conditions
- Trauma Injury, Modified Trauma Scoring Systems, FOUR Score
- Trial name
- FOUR-TRAUMA (NCT07819279)
- Where
- Iraq
- Volunteers
- 2,000 people
- Sponsor
- Al-Nahrain University
Wounds and Injuries, Burns
Clinical Registry Collecting Real World Evidence on Wound Care Treatments
The proposed registry Sponsor (Siddhey LLC) will collect data on various wound treatments in real life settings. Data collection will facilitate the analysis of the safety and efficacy of wound treatments.
- Conditions
- Wounds and Injuries, Burns, Mohs Surgery, Diabetic Foot Ulcer Mixed
- Trial name
- SIDDX (NCT06328010)
- Testing
- Various types of wound care treatments
- Where
- 12 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- Siddhey LLC
Pelvic Bone Injury, Pelvis Injury
RELIEVED (REgionaL anesthesIa PElVic fracturEs stuDy) Study. Regional Anesthesia (RA) Techniques for Pain Management in Pelvic Fractures: A Prospective, Monocentric, Pilot Cohort Study.
The goal of this observational clinical trial is to assess the impact of Regional Anesthesia (RA) techniques with the strongest anatomical and scientific support in controlling acute post-operative pain in pelvic/acetabular…
- Conditions
- Pelvic Bone Injury, Pelvis Injury, Acetabular Fractures, Acetabular Surgery
- Trial name
- RELIEVED (NCT07072286)
- Testing
- Regional Anesthesia, Multimodal analgesia
- Where
- Italy
- Volunteers
- 177 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Stroke, Multiple Sclerosis
Interest of a Musical Intervention on Stress Induced During Botulinum Toxin Injections in Spasticity (MUSIBOT)
Botulinum toxin (BT) injections are a painful treatment frequently used to treat spasticity following central neurological damage (stroke, multiple sclerosis, spinal cord injury, head trauma).
- Conditions
- Stroke, Multiple Sclerosis, Spinal Cord Injury, Head Trauma Injury
- Trial name
- MUSIBOT (NCT06920524)
- Testing
- Intervention group IM-IM
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Traumatic Brain Injury, Disruptive Behavior
Parent-Child Interaction Therapy (PCIT) for Children With Traumatic Brain Injury (TBI): A Stepped-Care Model
The purpose of this study is to understand how a stepped-care model of Parent-Child Interaction Therapy (Step-Up PCIT) addresses child behavioral problems among children between the ages of 2 and 7 with a traumatic brain injury…
- Trial name
- NCT06193382
- Testing
- PCIT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Stress-related Problem, Stress, Emotional
Effects of Parent-Adolescent Joint I-Interventions for Adolescents with Adverse Childhood Experiences
The study aims to examine the effectiveness of internet-based Parent-Adolescent Joint Interventions in improving the mental health outcomes of participants, specifically by reducing symptoms of depression, anxiety, and PTSD, as…
- Trial name
- EASY-PEP-i (NCT06650696)
- Testing
- PCE promotion, Psychoeducation, Emotiaonl skill enhancement
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University
Critical Illness, Heart Failure
Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress
Serious acute heart and lung illnesses like heart failure, severe COVID, and sepsis often leave survivors struggling not only physically, but also with lasting depression, anxiety, and stress.
- Conditions
- Critical Illness, Heart Failure, Sepsis, Ards
- Trial name
- Lift 3 (NCT07634419)
- Testing
- Lift mobile mindfulness, Enlighten Recovery education program
- Where
- 3 sites in United States
- Volunteers
- 450 people
- Sponsor
- Duke University
Depression, Anxiety, Trauma
Psychoeducation, Relaxation, PrOblem Solving, Activation, Cognitive Coping Therapy for Adolescents and Youth in HIV Care
The proposed PROACT study will test the effectiveness of a mental health intervention (psychotherapy) for multiple common mental health conditions (depressive, anxiety and trauma symptoms) among adolescents and youth with HIV in…
- Conditions
- Depression, Anxiety, Trauma, HIV-1-infection
- Trial name
- PROACT (NCT06247527)
- Testing
- Psychoeducation, Relaxation, PrOblem solving, Activation, Cognitive coping Therapy, Standard of care
- Where
- Kenya
- Volunteers
- 600 people
- Sponsor
- University of Nairobi
Trauma, Trauma Injury
Whole Blood in Trauma Patients With Hemorrhagic Shock
This study aims to evaluate among trauma patients with hemorrhagic shock the clinical impact of hemostatic resuscitation between whole blood vs.
- Conditions
- Trauma, Trauma Injury, Trauma, Multiple
- Trial name
- WEBSTER (NCT05634109)
- Testing
- Transfusion of blood products
- Where
- Colombia
- Volunteers
- 220 people
- Sponsor
- Fundacion Clinica Valle del Lili