Clinical trials: Transgenderism
Transgenderism
Expectations and Beliefs of Transgender People Regarding Hormonal Treatment
Hormonal treatment of gender dysphoria can have repercussions on metabolism, cardiovascular system and fertility and represents à potential oncological risk. According to the recommendations of the Endocrine society.
- Trial name
- NCT05474768
- Testing
- no intervention
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Central Hospital, Nancy, France
Surgery, Larynx
Voice Outcome of Glottoplasty, Cricothyroid Approximation, Thyroplasty, and Chondrolaryngoplasty
The purpose of this study is to measure the short- and long-term voice outcome and outcome predictors of glottoplasty, cricothyroid approximation, thyroplasty, and chondrolaryngoplasty using a prospective non-randomized…
- Conditions
- Surgery, Larynx, Transgenderism, Gender Dysphoria
- Trial name
- NCT06439290
- Testing
- Phonosurgery, Mastectomy/breast augmentation
- Where
- 2 sites in Belgium
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University Ghent
Transgenderism
Prospective Imaging Assessment of Perineo-pelvic Static's Evolution After Sexual Reassignment Surgery in MtF Transgender Patient, by Peno-scrotal Inversion Vaginoplasty Technique (TRANSPELV)
The research consists of adding to the usual MtF transgender patient undergoing vaginoplasty care course, static and dynamic perineo-pelvic MRI before, and at 6 and 24 months.
- Trial name
- TRANSPELV (NCT06093724)
- Testing
- Static and dynamic perineo-pelvic MRI
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Limoges
Transsexualism
Sex Steroids and the Serotonin Transporter
The aim of this study is to prove the influence of the sex steroid hormones estrogen, progesterone and testosterone on the serotonin transporter (5-HTT) binding using positron emission tomography (PET) and the selective…
- Trial name
- NCT01065220
- Testing
- Testolactone undecanoate, Lynestrenol, Cyproterone Acetate
- Where
- Austria
- Volunteers
- 32 people
- Sponsor
- Medical University of Vienna
Transgenderism, Reproductive Issues
Androgen Effects on the Reproductive Neuroendocrine Axis
This research study investigates whether male-level exogenous androgens inhibit the reproductive neuroendocrine axis in otherwise healthy (non-PCOS) females.
- Trial name
- NCT06450405
- Testing
- Testosterone Cypionate 50 MG/ML Injectable Solution
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Transgenderism
Evaluation of an Adaptative, Multidisciplinary, Reach-out Program, Facilitating Pre Exposition HIV Prophylaxis (PrEP) Prescription and Retention in Care, in a Group of Trans Womens (TW) at High Risk of HIV Infection.
Evaluation of an adaptative, multidisciplinary, reach-out program, facilitating pre exposition HIV prophylaxis (PrEP) prescription and retention in care, in a group of trans womens (TW) at high risk of HIV infection.
- Trial name
- PrEP à porter (NCT05415930)
- Testing
- Psychosocial assistance, Medical care, Legal-Administrative Assistance
- Volunteers
- 100 people
- Sponsor
- Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
Transgenderism, Gender Dysphoria
Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth
To evaluate the effect of estradiol with or without a prior gonadotropin releasing hormone analogue on insulin sensitivity and vascular function in transgender females compared to cisgender controls.
- Conditions
- Transgenderism, Gender Dysphoria, Insulin Sensitivity
- Trial name
- PUBERTY (NCT04596592)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Colorado, Denver
Transgenderism
Transgender Men, Non-binary Persons and Testosterone Treatment BODY IDENTITY CLINIC
The aim of this study is to investigate transgender men and non-binary persons before and during testosterone treatment. The study will focus on: Cardiovascular status Muscle strenght and power Aggression and quality of life…
- Trial name
- NCT04254354
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Marianne Andersen
Transgenderism, Insulin Sensitivity/Resistance
Puberty Suppression and Cardiometabolic Health
This observational study will evaluate the effect of puberty suppression on insulin sensitivity, metabolic rate and vascular health among transgender female youth at baseline and 6 months after initiation of a gondoatropin…
- Conditions
- Transgenderism, Insulin Sensitivity/Resistance, Endothelial Dysfunction, Vascular Stiffness
- Trial name
- NCT04482374
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Denver
Transsexualism
First Australian National Trans Mental Health Study
This is an Internet-based survey of transgender and transsexual (trans) people aged 18 years and older living in Australia. This population has received limited attention from public health researchers, planners, and…
- Trial name
- NCT02119377
- Testing
- questionnaire
- Where
- Australia
- Volunteers
- 946 people, healthy volunteers welcome
- Sponsor
- Curtin University
Gender Dysphoria, Gender Identity Disorder
i2TransHealth: Interdisciplinary, Internet-based Trans Health Care
i2TransHealth is a randomized controlled trial that investigates the outcomes of an internet-based health care approach for transgender and gender diverse (TGD) people.
- Conditions
- Gender Dysphoria, Gender Identity Disorder, Transsexualism, Gender Identity
- Trial name
- NCT04290286
- Testing
- i2TransHealth
- Where
- Germany
- Volunteers
- 186 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Transgenderism, Erectile Dysfunction
Epithesis Versus Prosthesis in Post-phalloplasty Transgender Patients.
Transgender and gender diverse (TGD) individuals most often choose for phalloplasty as a means to create masculine external genitalia.
- Conditions
- Transgenderism, Erectile Dysfunction, Prosthesis Durability, Gender Dysphoria
- Trial name
- EROS (NCT05883553)
- Testing
- Usability and added value of device within sexual activity
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Acne, Transgenderism
Factors Associated With the Acne Severity Among Transmen Population: a Cross-sectional Study
The goal of this observational cross-sectional study is to identify factors associated with severity of acne in Thai transmen receiving masculinizing hormone therapy.
- Trial name
- NCT06149065
- Testing
- Testosterone
- Where
- Thailand
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Transsexualism
Testosterone and Its Metabolites in GID
The purposes of this study are: to determine the role of testosterone versus dihydrotestosterone with respect to the following physiological functions: bone metabolism, body composition, insulin resistance and lipid profile to…
- Trial name
- NCT00146146
- Testing
- testosterone undecanoate alone, testosterone undecanoate plus letrozole, testosterone undecanoate plus dutasteride
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Unita Complessa di Ostetricia e Ginecologia
Breast Cancer, Gynecomastia
Effect of Suture Material on Postoperative Nipple Areolar Complex Widening
This will be a single-blinded study where participants are blinded to the suture type but the surgeon will draw a random, unmarked envelope containing the designated suture type at the start of the surgery.
- Conditions
- Breast Cancer, Gynecomastia, Transgenderism, Breast Asymmetry
- Trial name
- NCT06070324
- Testing
- Breast surgery, Suturing of surgical incision
- Volunteers
- 180 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Stigmatization, Sex Work
An Education Initiative to Reduce Stigma Towards Sex Workers and Sexual Minorities Among Nursing Students
Background: Sex workers and sexual minorities (SWSM) often encounter barriers when accessing healthcare services due to social stigma and discrimination.
- Conditions
- Stigmatization, Sex Work, Homosexuality, Transgenderism
- Trial name
- NCT06434805
- Testing
- sex workers and sexual minorities education workshop
- Where
- Hong Kong
- Volunteers
- 32 people
- Sponsor
- Hong Kong Metropolitan University
Transgender, Transgenderism
Cardiometabolic Health in Transgender Males
Transgender individuals are those with a gender identity opposite the sex they were assigned at birth. Approximately 1% of the population is transgender, equating to ~60,000 transgender Wisconsinites.
- Trial name
- NCT04977765
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Transgenderism, Reproductive Issues
Androgen Effects on the Reproductive Neuroendocrine Axis, 2025 Version
This research study investigates whether male-level exogenous androgens inhibit the reproductive neuroendocrine axis in otherwise healthy (non-PCOS) females.
- Trial name
- NCT07092527
- Testing
- Testosterone Cypionate 50 milligrams per millileter (mg/mL) Injectable Solution
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Hiv, Transgenderism
Drug-Drug Interaction Study in Trans Women Living With HIV
Introduction: Transgender (trans) women have been found to be at higher risk of and to be disproportionally affected by HIV. Trans women with HIV have also been found to have low usage and adherence rates to antiretroviral…
- Trial name
- T-DDI (NCT05663892)
- Testing
- Biktarvy 50/200/25 Tab, Estradiol Tablets
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Maple Leaf Research
Transgenderism, Gender Identity
Quality of Life of Transgender People - Implementation and Monitoring of an Online Cohort (e-QoL-Trans)
Transgender people have an identity or an expression gender that differs from the sex assigned to them at the birth. Transgender people and their needs remain misunderstood, and more generally by society.
- Trial name
- e-QoL-Trans (NCT05761678)
- Testing
- Questionnaire quality of life
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche