Clinical trials: Transgender Women
Transgender Women
Progesterone in Gender Affirming Hormone Therapy Study
This study aims to study the effects of Oral Progesterone in Transgender Women. The primary goal is to study the effect of progesterone on psychological distress and secondarily on sleep quality, breast size, quality of life and…
- Trial name
- NCT06807580
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Emory University
Gender Dysphoria, Adult, Blood Coagulation
Comparing the Effects of Sublingual Estradiol Treatment Versus Oral Estradiol With Cyproterone Acetate (CPA) Treatment on The Coagulation System in Transgender Women: A Prospective, Controlled Cohort Study
The goal of this clinical trial is to learn about the effects of different routes of estradiol administration on blood clotting in transgender women starting gender-affirming hormone therapy.
- Conditions
- Gender Dysphoria, Adult, Blood Coagulation, Coagulation Factors, Transgender Persons, M01.777.500
- Trial name
- NCT07145281
- Testing
- Estradiol (E2), Cyproterone Acetate (Androcur, BAY94-8367)
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Transgender Women, Voice Alteration
Gender-affirming Voice Training With Visual Feedback
The goal of this clinical trial is to learn if prototype software can be used to train vocal pitch and resonance in trans women.
- Trial name
- NCT07017595
- Testing
- Visual-acoustic biofeedback: experimental
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Cincinnati
Transgender Women, HIV/AIDS
Effects of Gender-Affirming Hormone Therapy Among Transgender Women
In this study, investigators plan to evaluate the cardiometabolic effects of initiating gender-affirming hormone therapy among transgender women with and without HIV.
- Conditions
- Transgender Women, HIV/AIDS, Cardiovascular Diseases, Metabolic Disease
- Trial name
- NCT04128488
- Testing
- Abdominal MR Imaging, Cardiac MRI/MRS, Oral Glucose Tolerance Testing
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Transgender Health, Gender Dysphoria
Evaluating Drug Interactions Between Doravirine With Estradiol and Spironolactone in Healthy Transgender Women
Transgender women living with Human Immunodeficiency Virus (HIV) may prioritize gender-affirming hormonal therapy over antiretroviral drug therapy.
- Conditions
- Transgender Health, Gender Dysphoria, Transgender Women, Human Immunodeficiency Virus
- Trial name
- IDENTIFY (NCT04283656)
- Testing
- Doravirine/Lamivudine/Tenofovir, Spironolactone 100mg, Estradiol 2mg
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Transgender Women, Substance Abuse
To Reach Unrestricted Services for Transgender Women
Florida has the fifth largest transgender population in the United States. Transgender women, particularly those of color, in the southern part of Florida are a marginalized population who are impacted by co-morbidities of…
- Conditions
- Transgender Women, Substance Abuse, Hiv
- Trial name
- TRUST (NCT03877497)
- Testing
- Adapted SBIRT-T for transgender women
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Transgender Women, Aids
Economic Navigation and Strengthening to Research Unrestricted Services for Transgender Women (ENTRUST)
The overall hypothesis is that stabilizing transgender women financially while providing them tailored counselling will increase their odds of them linking to substance use services, PrEP services if they do not have HIV, and…
- Conditions
- Transgender Women, Aids, Hiv
- Trial name
- NCT06202898
- Testing
- Baseline, ENTRUST, Control
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Central Florida
Men or Transgender Women Who Have Sex With Men
HIV Self-Testing AND Uptake and Retention of PrEP Among Older Adolescent MSM and TGW
This will be a prospective study that will enroll up to 600 older adolescent MSM and TGW from community-based clinics in Bangkok, Chonburi, Chiang Mai, and Songkhla.
- Trial name
- NCT03745495
- Where
- 7 sites in Thailand
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
HIV Infections, Transgender Women
Exploration of the Neo-Vagina Study
The current study will explore behavioral, surgical and biological neovaginal and rectal HIV transmission risks and feasibility of collection of blood and ano-genital samples (rectal, genital and neo-vaginal, including urine) for…
- Trial name
- NCT03049371
- Testing
- No Intervention for both groups
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Men Who Have Sex With Men and Transgender Women
Study to Evaluate the Feasibility of Integrating the Point-of-care Testing for Sexually Transmitted Infections and HIV Into Community-based Clinics for MSM and TGW in Thailand
This will be a prospective study that will enroll up to 2000 MSM and TG from community-based clinics in Bangkok, Chonburi, Chiang Mai, and Songkhla.
- Trial name
- NCT03580512
- Where
- 6 sites in Thailand
- Volunteers
- 2,000 people
- Sponsor
- Thai Red Cross AIDS Research Centre
HIV Prevention, Transgender Women
Long-acting Biomedical HIV Prevention in Transgender Women
Transgender women (TW) have unique challenges related to HIV prevention medication adherence. Left unaddressed, these challenges will prevent TW from accessing the promising long-acting HIV prevention tools in the development…
- Trial name
- NCT03856580
- Testing
- Alternative long-acting PrEP injection strategies, mHealth adherence app
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Transgender Women
Influences of Long Term Hormone Therapy on Physical Fitness and Vascular Function in Transgender Women
Transgender women who transitioned from male to female by hormone therapy demonstrate similar physical fitness and vascular function to males or females.
- Trial name
- NCT06116201
- Testing
- Estradiol, Estradiol and Anti-Androgen, No intervention
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
HIV, PrEP
Same-Day PrEP Initiation and Sexual Health for Transgender Women
Transgender women (trans women; assigned male sex at birth but identify as female) are at high risk for HIV infection, and are an important, under-researched population in sub-Saharan Africa.
- Conditions
- HIV, PrEP, Transgender Women, Sexually Transmitted Diseases, Bacterial
- Trial name
- NCT04491422
- Testing
- Integrated Next Steps Counseling with Real-Time Drug Level Feedback
- Where
- Uganda
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Makerere University
Speech Therapy, Transgender Women
Voice Feminisation in Transgender Women
The voice is a reflection of our identity. In the case of transgender women, there may be a gap between perceived male voice and female appearance.
- Conditions
- Speech Therapy, Transgender Women, Gender Dysphoria
- Trial name
- FemVoc (NCT03899896)
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Central Hospital, Nancy, France
HIV, Sexually Transmitted Infections
Peer-Delivered HIV Self-Testing, STI Self-Sampling and PrEP for Transgender Women in Uganda
Transgender women (TGW) are at high risk for HIV infection, and are an important, under-researched population in sub-Saharan Africa. Globally, HIV acquisition risk among TGW is 13 times higher than other adults aged 15-49 years.
- Conditions
- HIV, Sexually Transmitted Infections, PrEP, Transgender Women
- Trial name
- NCT04328025
- Testing
- Peer-delivered HIV self-testing, STI self-sampling and PrEP
- Where
- Uganda
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Makerere University