Clinical trials: Transcranial Magnetic Stimulation
Parkinson's Disease, Corticomotor Excitability
HF-rTMS Primed Balance Training on Corticomotor Excitability, Balance, and Gait in Parkinson's
This study aims to investigate the effects of repeated transcranial magnetic stimulation combined with modified otago exercise program balance training intervention on motor cortex excitability, balance, and gait performance in…
- Conditions
- Parkinson's Disease, Corticomotor Excitability, Balance Control, Gait Performance
- Trial name
- NCT07653256
- Testing
- high-frequency repetitive transcranial magnetic stimulation
- Volunteers
- 20 people
- Sponsor
- Chung Shan Medical University
Hemiparesis, Neonatal Stroke
Transcranial Magnetic Stimulation in Children With Stroke
This is a pilot study of repetitive transcranial magnetic stimulation (rTMS) to test tolerance and efficacy in children who have hemiparesis from acquired or presumed perinatal stroke.
- Conditions
- Hemiparesis, Neonatal Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- TMSCS (NCT01637129)
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Nationwide Children's Hospital
Spinal Cord Injuries, Depression
Dosing rTMS for Depression Post-SCI
Depression is a leading cause of disability worldwide and is more commonly seen in individual's post-spinal cord injury (SCI) than in the general population.
- Conditions
- Spinal Cord Injuries, Depression, Depressive Disorder, Major
- Trial name
- NCT05553353
- Testing
- repetitive transcranial magnetic stimulation--Active
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Major Depressive Disorder (MDD)
Electroencephalography-based Precise Repetitive Transcranial Magnetic Stimulation Treatment
This study will focus on the hypothesis that repetitive transcranial magnetic stimulation (TMS) based on EEG personalized modulation may be more effective in promoting symptomatic relief of major depressive disorder (MDD), and…
- Trial name
- NCT06385405
- Testing
- Individualized alpha frequency Transcranial Magnetic Stimulation (αTMS) Treatment, 10Hz-frequency TMS treatment over the left dorsolateral prefrontal cortex (DLPFC)
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Shanghai Mental Health Center
Major Depressive Disorder
Effects of Intravenous (IV) Citalopram Hydrochloride During Transcranial Magnetic Stimulation in Major Depressive Disorder (MDD)
This study will recruit 30 subjects diagnosed with Major Depressive Disorder (MDD). Subjects will be recieve one infusion treatment of citalopram or placebo and 10 treatments of a form of transcranial magnetic stimulation, theta…
- Trial name
- NCT04846829
- Testing
- intermittent theta burst stimulation, intravenous citalopram hydrochloride (CIT), continuous theta burst stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Los Angeles
Transcranial Magnetic Stimulation
Repetitive Transcranial Magnetic Stimulation as a Potential Tool to Reduce Sexual Arousal
Hyper- and hyposexuality occur frequently in a variety of psychiatric disorders and are difficult to treat. While there is meta-analytic evidence for the significant effect of non-invasive brain stimulation on drug and food…
- Trial name
- NCT04209309
- Testing
- repetitive transcranial magnetic stimulation
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Regensburg
Major Depressive Disorder
Prediction of the Response to a Course of Transcranial Magnetic Stimulation (rTMS) Based on Heart Rate Variability
Changes in heart rate variability following a single session of rTMS will be tested as a predictor of response to a course of 30 rTMS sessions in patients with major depressive disorder (MDD).
- Trial name
- DEP&MOD (NCT06451809)
- Testing
- repetitive transcranial magnetic stimulation
- Where
- 9 sites in France
- Volunteers
- 160 people
- Sponsor
- GCS CIPS
Aging
Neural Underpinnings of Turning
Older adults and stroke survivors often have difficulty performing complex walking tasks, due in part to changes in the brain. One task often overlooked is turning, which can lead to injury when performed poorly.
- Trial name
- NCT05475236
- Testing
- Experimental: Locomotor Learning
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke, Stroke, Ischemic
Cortico-cortical Stimulation and Robot-assisted Therapy for Upper Limb Recovery After Stroke (CCS&RAT)
The purpose of this study is to tested the effect of combination of a paired associative stimulation of two functional interconnected areas of the cerebral cortex (posterior-parietal cortex and primary motor cortex) with…
- Trial name
- CCS&RAT (NCT05478434)
- Testing
- Cortico-cortical stimulation plus robot-assisted therapy
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Parkinson's Disease
Study on the Effect of External Magnetic Stimulation on Patients With Parkinson's Disease
The purpose of this research study is to test the usefulness of external magnetic stimulation (EMS) for treating the motor, cognitive, and neuropsychiatric symptoms of Parkinson's disease (PD).
- Trial name
- NCT00841464
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Parkinson's Disease Research, Education, and Clinical Center, Philadelphia
Bipolar Depression
Treatment of Bipolar Depression With H1-Coil Deep Brain rTMS: Clinical-Cognitive and Safety Evaluation
The treatment of bipolar disorders is always a challenge in daily practice. Mood stabilizers are partially effective in the treatment of depressive phase of the illness, although there are some reports relating to the…
- Trial name
- rTMSH1Coil (NCT01962350)
- Testing
- Deep Brain Transcranial Magnetic Stimulation
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Mild Cognitive Impairment (MCI), Insomnia
Treating Insomnia in Mild Cognitive Impairment
The goal of this study is to test a new way to improve sleep quality in persons living with mild cognitive impairment. The treatment combines a safe and gentle way to stimulate the brain, called transcranial magnetic stimulation…
- Trial name
- NCT06687161
- Testing
- Transcranial Magnetic Stimulation (TMS) therapy, Cognitive behavioral therapy for insomnia (CBT-I)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Beth Israel Deaconess Medical Center
Alzheimer&Amp;Amp;#39;s Disease, Alzheimer Disease
Large-coil Parietal Repetitive Transcranial Magnetic Stimulation (rTMS) for Alzheimer Disease (AD)
The goal of this clinical trial is to learn if using large-coil (or "deep") repetitive transcranial magnetic stimulation (rTMS) targeting the precuneus and surrounding areas is feasible, tolerable, and potentially efficacious for…
- Conditions
- Alzheimer&Amp;Amp;#39;s Disease, Alzheimer Disease, Dementia Alzheimer Type, Mild Alzheimer&Amp;Amp;#39;s Disease
- Trial name
- PROMIS-AD (NCT06597942)
- Testing
- TMS
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of California, Los Angeles
Vascular Parkinsonism
rTMS Treatment in Vascular Parkinsonism
Vascular parkinsonism (VP), parkinsonism resulting from ischemic cerebrovascular disease, was suggested in 1929. The main features are wide-based gait, postural instability, and falls, which make patients with VP frustrated.
- Trial name
- rTMS (NCT03720691)
- Testing
- Real rTMS Supplementary motor area
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Inje University
Smoking, Cigarette, Craving
QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt
Cigarette smoking constitutes the greatest preventable cause of mortality and morbidity in the US. The most critical period for long term success of smoking cessation appears to be in the first 7 days after the quit date.
- Conditions
- Smoking, Cigarette, Craving, Addiction, Nicotine
- Trial name
- NCT03576768
- Testing
- Real cTBS, Real iTBS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medical University of South Carolina
Spasmodic Dysphonia, Laryngeal Dystonia
rTMS in Spasmodic Dysphonia
Focal dystonia is a neurological movement disorder characterized by excessive involuntary muscle contractions of any body part. Spasmodic dysphonia (SD) is a type of focal dystonia characterized by excessive contraction of…
- Trial name
- NCT02957942
- Testing
- 1Hz repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Dystonia
Interactions Between Striatum and Cerebellum in ADCY5 and PRRT2 Dystonias
The investigators will study the relationship between the basal ganglia and the cerebellum in dystonia by associating cerebellar stimulations with functional magnetic resonance imaging analysis.
- Trial name
- AMEDYST (NCT03481491)
- Testing
- transcranial magnetic stimulation of the cerebellum
- Where
- France
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Spinal Cord Stimulation, Electric Stimulation Therapy
Evaluating Safety and Feasibility of Transcutaneous Spinal Cord Stimulation Following Traumatic and Non-Traumatic Spinal Cord Injury: A Pilot Study
The study will be a non-randomized, non-blinded pilot study to analyze the safety and feasibility of a non-significant risk device, transcutaneous spinal cord stimulation.
- Conditions
- Spinal Cord Stimulation, Electric Stimulation Therapy, Traumatic Spinal Cord Injury, Cervical Myelopathy
- Trial name
- STIM (NCT06520020)
- Testing
- Transcutaneous Spinal Cord Stimulation (Tc-SCS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Francis Farhadi
Treatment Resistant Depression
TBS in Major Depression
Background Major depression is associated with morbidity and increased mortality. Along with the psychological strain depression represents a high socioeconomic burden costing Europe more than €113 billion/year.
- Trial name
- NCT03257397
- Testing
- theta-burst stimulation (TBS) using a MagPro X1000
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Rupert Lanzenberger
Transcranial Magnetic Stimulation
Effect of Transcranial Magnetic Stimulation on Dynamic Cerebral Autoregulation in Healthy Adults
The purpose of this study is to determine the effect of transcranial magnetic stimulation with different stimulation modes ( 1Hz, 10Hz, sham stimulation ) on cerebral autoregulation.
- Trial name
- NCT05915923
- Testing
- 1 Hz Repetitive transcranial magnetic stimulation, 10 Hz Repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yi Yang