Clinical trials: Transcatheter Left Atrial Appendage Closure
Cardiovascular Diseases, Arrhythmia
The Safety and Efficacy of Radiofrequency Ablation After Left Atrial Appendage Occlusion.
Objective: To evaluate the safety and efficacy of transcatheter atrial fibrillation ablation 1 month after WATCHMAN FLX left atrial appendage closure in patients with nonvalvular atrial fibrillation.
- Trial name
- NCT06984731
- Testing
- left atrial appendage closure, radiofrequency ablation
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Affiliated Hospital of Nantong University
Atrial Fibrillation
Changes of Left Atrial Function and Quality of Life After Transcatheter Closure of Left Atrial Appendage in Patients With Atrial Fibrillation
A total of 105 (AF) patients with atrial fibrillation are scheduled to undergo surgery and will be divided into three groups. Left atrial appendage occlusion ((LAAC)), radiofrequency ablation guided by three-dimensional mapping…
- Trial name
- NCT04376606
- Testing
- Left atrial appendage closure, Radiofrequency ablation, LAAC combined with radiofrequency ablation group
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Ruiqin xie
Transcatheter Left Atrial Appendage Closure, Frailty
Frailty in Patient Undergoing Percutaneous Left Atrial Appendage Closure.
To assess the prevalence and severity of frailty in patients undergoing LAAC, as well as its association to peri-procedural and long-term outcomes and quality of life.
- Trial name
- Frail-LAAC (NCT05257954)
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Josep Rodes-Cabau
Left Atrial Appendage Incomplete Closure
Transcatheter Leak Closure With Detachable Coils Following Incomplete Left Atrial Appendage Closure Procedures
Although the clinical impact of left atrial appendage (LAA) leaks still requires confirmation, the open pouch with residual flow resulting from incomplete LAA closure may promote blood stagnation and thrombus formation, and…
- Trial name
- TREASURE (NCT03503253)
- Testing
- Interlock-35 Fibered IDC Occlusion System, Concerto Helix Detachable Coil System, Azur Peripheral Coil System
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Texas Cardiac Arrhythmia Research Foundation
Atrial Fibrillation, Stroke Prevention
Computational Simulation to Plan for Percutaneous Left Atrial Appendage Closure
To ensure a successful percutaneous left atrial appendage (LAA) closure, it is important to select the correct size of the closure device used for each patient.
- Trial name
- NCT04180605
- Testing
- Additional support for preoperative planning of LAA closure procedures, Left atrial appendage closure
- Where
- 12 sites in Belgium, Canada and 5 more
- Volunteers
- 200 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Aortic Valve Disorder
Combined Transcatheter Aortic Valve Implantation and Percutaneous Closure of the Left Atrial Appendage
Atrial fibrillation (AF) is a common comorbidity of patients candidates to transcatheter aortic valve implantation (TAVI). The management of chronic oral anticoagulation (OAC) for the prevention of ischemic stroke is very…
- Trial name
- TAVI-LAAC (NCT02678871)
- Testing
- Lotus or ACURATE neo Heart valve system (or subsequent CE marked iterations), WATCHMAN
- Where
- 6 sites in Germany, Italy and 2 more
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Acute Ischemic Stroke AIS, Stroke Treatment
CardioLogical Interventions and Acute strOke Treatment sTudy
The study aims to investigate characteristics and prognosis of ischemic stroke cases following cardiological interventions, focusing on the effectiveness and safety of acute ischemic stroke treatments.
- Conditions
- Acute Ischemic Stroke AIS, Stroke Treatment, PCI Patients, Aortic Valve Replacement
- Trial name
- CLOT (NCT07314476)
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University of L'Aquila