Clinical trials: Tramadol
Labor Pain
Outcome of Combined Tramadol and Paracetamol Versus Pentazocine as Labour Analgesia Among Parturients
Labour is a very painful experience and epidural analgesia is considered the gold standard for pain relief in labour. Epidural scarcity, cost and shortage of skilled personnel to administer it is a limitation to it's usage in…
- Trial name
- OCTAPPENALA (NCT05565274)
- Volunteers
- 166 people
- Sponsor
- Federal Medical Centre, Yenagoa
Postoperative Pain
Effectivness of Tramadol or Topic Lidocaine on Postoperative Analgesia in Laparoscopic Colorectal Resection.
Comparison of different postoperative analgesia after laparoscopic colorectal surgery
- Trial name
- NCT05831761
- Testing
- Comparison of analgesic efficacy protocol
- Volunteers
- 83 people
- Sponsor
- University Medical Centre Ljubljana
Aging, Pain
PK PD of the Enantiomers of Tramadol and O-desmethyltramadol in Elderly and Young Subjects
This study evaluates the pharmacokinetics and pharmacodynamics of the enantiomers of tramadol and O-desmethyltramadol (ODM) in generally healthy young and elderly adults.
- Trial name
- NCT02329561
- Testing
- Tramadol extended release 200 mg, CP/T
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
General Surgery
Inflammation and Postoperative Tramadol Analgesia
Patients will be admitted in the intensive care unit after major abdominal surgery. All patients will receive 100 mg of tramadol intravenously every 6 hours.
- Trial name
- NCT04330157
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Osijek University Hospital
Postoperative Pain, Hemidiaphragmatic Paresis
Combined Suprascapular and PECS I Blocks Versus Interscalene Block for Shoulder Arthroscopy
Shoulder arthroscopy can cause moderate to severe pain after surgery. An interscalene block is commonly used to reduce this pain, but it may temporarily weaken movement of the diaphragm on the treated side.
- Trial name
- NCT07852754
- Testing
- suprascapular nerve block, PECS I Block, Interscalene Brachial Plexus Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cansu Ofluoğlu
Tramadol for Labor Analgesia
Tramadol for Labor Analgesia: a Placebo Controlled Randomised Control Trial
Tramadol for labor analgesia: a low risk placebo controlled randomised control trial
- Trial name
- NCT02999594
- Testing
- Tramadol Hydrochloride, Distilled Water
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Maulana Azad Medical College
Chronic Pain
A Long-term Efficacy and Safety Study of Tramadol Hydrochloride Plus Acetaminophen (JNS013) in Japanese Participants With Chronic Pain
The purpose of this study is to evaluate the efficacy and safety of tramadol hydrochloride plus acetaminophen (JNS013) with long term administration in participants with chronic pain.
- Trial name
- NCT00736957
- Testing
- Tramadol Hydrochloride (HCL) plus Acetaminophen (JNS013)
- Where
- 25 sites in Japan
- Volunteers
- 219 people
- Sponsor
- Janssen Pharmaceutical K.K.
Healthy
A Dose Linearity Study of the Labopharm Formulation of Tramadol HCl/Contramid®, 100 mg, 200 mg and 300 mg After A Single Oral Administration In Fasting Condition, In Healthy Human Volunteers
The purposes of this study were: To evaluate the plasma pharmacokinetic profile of tramadol and its principal metabolite, the O-desmethyltramadol, after a single oral administration of 100, 200 and 300 mg of tramadol as the…
- Trial name
- NCT00834808
- Testing
- Tramadol HCl
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Labopharm Inc.
Labour Duration
Intravenous Paracetamol Versus Intramuscular Tramadol in Shortening the Duration of Labour.
It is a well established fact that the pain of labour can be excrutiating and ways to shorten the duration of labour has been sought after.
- Trial name
- NCT07394491
- Testing
- paracetamol, Tramadol hydrochloride
- Where
- Nigeria
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Federal Teaching Hospital Abakaliki
Acute Pain, Postoperative Pain
Efficacy and Safety of Etoricoxib-tramadol Tablet in Acute Postoperative Pain
The goal of the present phase IIb clinical trial was to compare the safety and efficacy of the fixed-dose combination etoricoxib-tramadol 120mg/100mg tablet (once a day, for three days) versus naproxen 220mg tablet plus tramadol…
- Trial name
- NCT05995912
- Testing
- etoricoxib-tramadol, Naproxen, Tramadol
- Where
- Mexico
- Volunteers
- 58 people
- Sponsor
- Laboratorios Liomont
Arthritis, Rheumatoid
ULTRACET (Tramadol Hydrochloride and Acetaminophen) for the Treatment of Rheumatoid Arthritis Pain.
The purpose of this study is to assess the effectiveness of ULTRACET® (a combination analgesic) as add-on therapy in rheumatoid arthritis patients taking an NSAID (e.g.
- Trial name
- NCT00246168
- Testing
- tramadol hydrochloride + acetaminophen
- Volunteers
- 277 people
- Sponsor
- Janssen Korea, Ltd., Korea
Dental Pain and Sensation Disorder, Anesthesia, Local
Impact of Tramadol Addiction On Dental Anesthesia Success
The aim is to investigate and to find a correlation between tramadol addiction misuse among Algerian males and Dental Local Anesthesia success while performing dental care and oral surgeries.
- Conditions
- Dental Pain and Sensation Disorder, Anesthesia, Local, Addiction, Opioid
- Trial name
- NCT05908305
- Testing
- articaine@ (4% 1:100000 epinephrine) dental anesthesia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Algiers
Pharmacokinetics
Administration of Tramadol and Ketorolac Separately and Simultaneously to Assess a Potential Pharmacokinetic Interaction
Tramadol (Tradol) and ketorolac (Dolac) are marketed products to treat acute pain. This study was performed to determine if both medications can be given to a patient simultaneously without a change of the products'…
- Trial name
- NCT03767036
- Testing
- Tramadol hydrochloride 25 mg capsule, Ketorolac Tromethamine 10 mg tablet
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Shivering Caused by Spinal Anesthesia
COMPARISON OF INTRAVENOUS DEXMEDETOMEDINE AND TRAMADOL FOR POST OPERATIVE SHIVERING AFTER SPINAL ANESTHESIA FOR CAESAREAN SECTION
To compare the mean time of cessation of post-operative shivering after receiving intravenous dexmedetomidine versus tramadol in patients undergoing caesarean delivery under spinal anaesthesia.
- Trial name
- NCT07332572
- Testing
- Tramadol, Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
Post Operative Pain, Cesarean Section
The Effect of Intravenous Infusion of Tramadol-ondansetron on Recovery After Caesarean Section.
It will be a prospective observational cohort study. The investigators will compare post-cesarean section recovery in patients receiving intravenous infusion of tramadol-ondansetron versus epidural catheter with infusion of local…
- Conditions
- Post Operative Pain, Cesarean Section, Tramadol, Postoperative Recovery
- Trial name
- TRON (NCT05879536)
- Testing
- Tramadol-ondansetron continuous infusion, Ropivacaine via epidural catheter
- Where
- Spain
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe
Pain, Postoperative Pain
A Comparative Study of JNS013 in Participants With Post-Tooth-Extraction Pain
The purpose of this study is to evaluate the efficacy and safety of JNS013 with single oral dose administration in participants with pain after tooth-extraction of mandibular impacted wisdom tooth.
- Trial name
- NCT00737048
- Testing
- Tramadol Hydrochloride, Acetaminophen, Tramadol plus Acetaminophen
- Where
- 11 sites in Japan
- Volunteers
- 328 people
- Sponsor
- Janssen Pharmaceutical K.K.
Cancer Pain
Efficacy of Duloxetine in Conjunction With Tramadol for Chronic Cancer Pain
Cancer pain is one of the most common and problematic symptoms. Opioids are typically the most common drugs used in the treatment of cancer pain,they are limited due to their side effects.
- Trial name
- NCT05311774
- Testing
- Duloxetine 30 mg, Tramadol
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Assiut University
Trauma, Opioid Analgesic Adverse Reaction
Role of Prophylactic Metoclopramide With Tramadol in Trauma Patients
Tramadol is widely used as analgesic in trauma patients. However, it causes side effects, most notably nausea and vomiting. This study aim to determine the role of prophylactic metoclopramide in preventing tramadol induced nausea…
- Trial name
- NCT03383315
- Testing
- Tramadol, Metoclopramide
- Where
- Malaysia
- Volunteers
- 191 people
- Sponsor
- University of Malaya
Gastrointestinal Cancer
Effect of COX-2 Selective Inhibitors on Postoperative Insulin Resistance After Gastrointestinal Laparoscopic Surgery
It is well established that the resistance to the effects of insulin on glucose metabolism develops with a lot of stress hormone release after surgical trauma.
- Trial name
- NCT01930318
- Testing
- parecoxib
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Jinling Hospital, China
Tendon Injuries
Multimodal Analgesia Strategies After Major Shoulder Ambulatory Surgery
This study evaluates the addition of tramadol, or nefopam or opioid to paracetamol and ketoprofene in the treatment of pain in adults after shoulder ambulatory surgery.
- Trial name
- Shoulder1 (NCT04110665)
- Testing
- Tramadol, Nefopam 20 MG/ML, Morphine Sulfate
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes