Clinical trials: Trachomatous Trichiasis
Trachomatous Trichiasis
A Trial of Epilation Verses Surgery for Minor Trichiasis
Trachoma is the leading infectious cause of blindness worldwide. Recurrent infection by Chlamydia trachomatis causes a gradual scarring process of the inner surface of the eyelid (conjunctiva) leading to in-turning of the eyelids…
- Trial name
- NCT00522912
- Testing
- Trichiasis surgery, Epilation
- Where
- Ethiopia
- Volunteers
- 1,300 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Trichiasis, Surgery
Repeat Surgery for Patients With Post-operative Trachomatous Trichiasis Trial
The objective of this study is to determine if there is a significant difference in post-operative trichiasis at 12 months comparing a new procedure, the Bevel/rotate/advance procedure (BRAP), to the Trabut procedure among repeat…
- Trial name
- PTT (NCT03886519)
- Testing
- BRAP (Bevel/rotate/advance procedure), Trabut
- Where
- Ethiopia
- Volunteers
- 886 people
- Sponsor
- University of North Carolina, Chapel Hill
Trachomatous Trichiasis, Trachoma
A Trial of Non-absorbable Versus Absorbable Sutures for Trichiasis Surgery
Trachoma is the leading infectious cause of blindness worldwide. Recurrent infection by Chlamydia trachomatis causes in-turning of the eyelids / lashes (trichiasis), leading to corneal damage and blindness.
- Trial name
- NCT00522860
- Testing
- Trichiasis surgery with absorbable sutures, Trichiasis surgery with non-absorbable sutures
- Where
- Ethiopia
- Volunteers
- 1,300 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Trichiasis, Trachoma
Fluorometholone as Ancillary Therapy for TT Surgery
The investigators aim to evaluate a new potentially cost-effective approach to improving trichiasis surgery outcomes, perioperative topical anti-inflammatory therapy.
- Conditions
- Trichiasis, Trachoma, Bilamellar Tarsal Rotation
- Trial name
- NCT01949454
- Testing
- Fluorometholone 0.1% ophthalmic solution
- Where
- Ethiopia
- Volunteers
- 154 people
- Sponsor
- University of Pennsylvania
Trachomatous Trichiasis (TT), Eye Diseases
FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial
This study aims : To assess the efficacy of fluorometholone 0.1% one drop twice daily for four weeks in reducing the incidence of post-operative trachomatous trichiasis (TT) when given as adjunctive therapy with TT surgery in the…
- Conditions
- Trachomatous Trichiasis (TT), Eye Diseases, Eyelid Diseases, Trachomatous
- Trial name
- FLAME (NCT04149210)
- Testing
- Fluorometholone 0.1% Oph Susp, Artificial Tears
- Where
- Ethiopia
- Volunteers
- 2,410 people
- Sponsor
- Massachusetts Eye and Ear Infirmary