Clinical trials: Trachea
Tracheitis, Tracheobronchitis
Evaluation of Effectiveness of the Treatment After Repeated Administration of Klacid®SR
This post-marketing observational study (PMOS) will be conducted in a prospective, single-arm, single-country, multicenter format.
- Conditions
- Tracheitis, Tracheobronchitis, Bronchitis, Chronic Bronchitis
- Trial name
- NCT01130883
- Where
- 135 sites in Czechia
- Volunteers
- 3,130 people
- Sponsor
- Abbott
Excessive Dynamic Airway Collapse, Tracheobronchomalacia
Symptomatic Treatment of Excessive Dynamic Airway Collapse Using Daytime Portable Continuous Positive Airway Pressure
The aim of this study is to assess the benefit of a portable ventilator generating positive end-expiratory pressure on exercise tolerance in patients with Excessive dynamic airway collapse (EDAC) and tracheobronchomalacia (TBM).
- Trial name
- EPOC (NCT02763631)
- Testing
- Experimental: Treatment, Experimental: Run In Phase
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Intubation Complication
Nasal Intubation：a Comparison of Different Endotracheal Tubes
Either uses two different endotracheal tubes to pass the nasal cavity and to compare the effects on the secretion and bleeding volume of patients during intubation to facilitate nasotracheal tube advancement.
- Trial name
- NCT05112783
- Testing
- Henan Tuoren Endotracheal Tube, Smiths Portex Tracheal Tubes
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Tracheal Stenosis
Investigation of the Effect of Systemic Steroids on Treatment and Prevention of Recurrent Tracheal Stenosis in Postoperative Patients
tracheal stenosis is the result of abnormal wound-healing processes leading to hypertrophic scar formation and obstruction of the airway lumen by excess granulation tissue.
- Trial name
- NCT02855502
- Testing
- Prednisolone
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- National Research Institute of Tuberculosis and Lung Disease, Iran
Diaphragmatic Hernia, Lung Disease
Fetal Tracheal Balloon Study in Diaphragmatic Hernia
The purpose of this phase 2 limited study is to examine whether prenatal intervention correct the lung underdevelopment associated with severe diaphragmatic hernia.
- Trial name
- NCT00966823
- Testing
- Fetal tracheal obstruction with detachable balloon (device)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Rhode Island Hospital
Anesthesia Intubation Complication, Tracheal Disease
The Effect of Prophylactic Ketorolac on Sore Throat After Thyroid Surgery
Sore throat is one of most frequent complaints related to general anesthesia with tracheal intubation. Although sore throat is regarded as a minor and short-lasting discomfort after surgery, its incidence and intensity in high…
- Trial name
- NCT02039427
- Testing
- Ketorolac, Dexamethasone
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Yeungnam University College of Medicine
Tracheo Esophageal Fistula, Congenital Diaphragmatic Hernia
Cerebral Blood Flow in Neonates During Thoracoscopic Surgeries
the aim of this study is to compare the effect of different modes of mechanical ventilation by using volume-controlled ventilation and pressure-controlled ventilation on cerebral blood flow monitored by cerebral oximetry during…
- Trial name
- NCT04507295
- Testing
- cerebral oximetry ( INVOS 5100 )
- Volunteers
- 30 people
- Sponsor
- Cairo University
Trachea Diseases, Tracheal Stenosis
Feasibility of Tracheobronchial Reconstruction Using Allogenic Aortic Patch in Children
Feasibility and safety of repairing tracheal and bronchial defects in infants and children using cryopreserved donor aortic patches.
- Conditions
- Trachea Diseases, Tracheal Stenosis, Tuberculosis; Tracheitis, Airway Disease
- Trial name
- NCT07240259
- Testing
- Cryopreserved aorta
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- National Taiwan University Hospital
Stenosis Trachea
Cryospray Therapy for Benign Airway Stenosis
This is a clinical evaluation to assess the effectiveness of cryospray therapy used in addition to current standard of care endoscopic therapies in preventing short term recurrent airway stenosis with a multicentric outcome…
- Trial name
- CRYOSTASIS (NCT06085209)
- Testing
- The truFreeze Spray Cryotherapy, Ballon dilation, Radial Incision
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Virginia Commonwealth University
Tracheoesophageal Fistula, Esophageal Atresia
Phenotypic and Genetic Assessment of Tracheal and Esophageal Birth Defects in Patients
The investigators propose a preliminary study performing exome sequencing on samples from patients and their biologically related family members with tracheal and esophageal birth defects (TED).
- Conditions
- Tracheoesophageal Fistula, Esophageal Atresia, Laryngeal Cleft, Tracheal Stenosis
- Trial name
- TED (NCT03455881)
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Tracheal Stenosis, COVID-19
Relationship Between Post-Intubation Tracheal Stenosis and Covid-19
Tracheal stenosis (TS) is a serious complication that occurs in approximately 6-22% of patients due to prolonged endotracheal intubation.
- Conditions
- Tracheal Stenosis, COVID-19, Post-Intubation Subglottic Stenosis, Intensive Care Unit
- Trial name
- NCT05682651
- Testing
- tracheal stenosis follow-up file
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Ankara City Hospital Bilkent
Tracheal Stenosis
Observational Study for the Evaluation of Tracheal Stenosis in COVID-19 Patients
Define the actual incidence of tracheal stenosis in patients who underwent either prolonged intubation or tracheostomy and to compare incidence, clinical course and outcome between COVID-19 and non-COVID-19 patients.
- Trial name
- TS1 (NCT04686721)
- Testing
- Chest CT scan + baseline spirometry
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Clinico Humanitas
Uncuffed Endotracheal Intubation
Ultrasound and Paediatric Endotracheal Tube Size
The aim of the present study was to evaluate the role of ultrasound in paediatric patients to compare the correct size of an uncuffed endotracheal tube (ETT) with the minimal transverse tracheal diameter (MTTD) measured by…
- Trial name
- NCT01535300
- Testing
- Ultrasonography of the trachea
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Heidelberg University
Excessive Central Airways Collapse, Respiratory Disease
Portable Continuous Positive Airways Pressure (CPAP) in Excessive Central Airway Collapse (ECAC) Study
This study will investigate the role of a portable Continues Positive Airway Pressure device (pCPAP) in management of patients with symptomatic Excessive Central Airway Collapse (ECAC).
- Conditions
- Excessive Central Airways Collapse, Respiratory Disease, Tracheobronchomalacia, Excessive Dynamic Airway Collapse
- Trial name
- NCT06072872
- Testing
- Use of portable CPAP
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Malignant Airway Obstruction
A Trail of a Novel Tracheal Radioactive Stent for the Malignant Airway Obstruction
The aim of this study was to evaluate the safety and effectiveness of an radioactive airway stent loaded with 125I seeds compared to a conventional airway stent in patients with malignant airway obstruction caused by both primary…
- Trial name
- NCT02565927
- Testing
- Traditional airway stent, Iodine-125 seeds
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhongda Hospital
Infection
Coated Endotracheal Tube and Mucus Shaver to Prevent Hospital-Acquired Infections
This study, conducted at the San Gerardo Hospital in Milan, Italy, will examine whether a bacteriocidal-coated endotracheal tube (breathing tube) cleaned with a device called a Mucus Shaver is safe and effective in preventing…
- Trial name
- NCT00341354
- Testing
- Prolonged Mechanical Ventilation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Foreign Bodies, Tumor
The Effects of High-flow Nasal Oxygen on Oxygenation During Rigid Bronchoscopy Under General Anesthesia in Pediatric Patients
The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on maintenance of oxygenation and removal of carbon dioxide during apnoeic period in pediatric patients undergoing general…
- Conditions
- Foreign Bodies, Tumor, Stenosis of Trachea, Bronchus
- Trial name
- NCT03905733
- Testing
- Optiflow
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Thyroid Cancer
Patient-Customized Bioprinting Technology for Practical Regeneration of the Respiratory Tract (Trachea)
This clinical trial aims to assess the effectiveness and safety of a novel approach utilizing biopolymers, hydrogels, mucous membranes, and cartilage tissue regeneration cells integrated into 3D bioprinting technology for the…
- Trial name
- NCT06051747
- Testing
- Three-dimensional patient-specific bioprinting trachea implantation
- Where
- South Korea
- Volunteers
- 1 people
- Sponsor
- Ja Seong Bae, MD, phD
Tracheomalacia, Tracheobronchomalacia
Tracheal Mechanics During Bronchoscopy
The main purpose of this study is use a new type of measurement to help decide what kind of therapy would help people with a collapsing windpipe or tracheomalacia.
- Trial name
- NCT00536315
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Airway Disease
Characterisation of Large Airway Collapse During Exercise (LACE)
The large central airways (i.e. trachea and bronchi) act as a conduit to enable lower airway ventilation but also facilitate airway clearance during dynamic manoeuvres, such as coughing.
- Trial name
- LACE (NCT04264052)
- Testing
- CBE & MRI
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Imperial College London