Clinical trials: Total Thyroidectomy
Total Thyroidectomy, Bilateral Neck Exploration for Primary Hyperparathyroidism
Intra-operative Infra-red Fluorescent Imaging in Thyroid and Parathyroid Surgery
Reliable identification of parathyroid glands is critical to the success of thyroid and parathyroid surgery. In thyroid surgery, inadvertent injury to parathyroid glands may cause temporary or permanent hypoparathyroidism (low…
- Trial name
- NCT02089542
- Testing
- MB and fluorescent imaging
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Postoperative Hypocalcemia, Postoperative Hypoparathyroidism
Ionized Calcium Changes for Predicting Postoperative Hypocalcemia After Total Thyroidectomy
This prospective observational study aims to evaluate whether changes in ionized calcium levels measured by blood gas analysis during the preoperative, intraoperative, and postoperative periods can predict postoperative…
- Conditions
- Postoperative Hypocalcemia, Postoperative Hypoparathyroidism, Total Thyroidectomy
- Trial name
- NCT07701824
- Testing
- Calcium
- Where
- Turkey (Türkiye)
- Volunteers
- 327 people
- Sponsor
- Emrecan Deniz
Thyroid, Cancer
Thyroid Cancer in United Arab Emirates
The main objective of the study is to assess the trend of clinicopathological features and treatment modalities in patients with thyroid cancer in the largest oncology center in the United Arab Emirates (UAE).
- Trial name
- NCT04763122
- Testing
- not applicable as it is a retrospective study
- Volunteers
- 762 people
- Sponsor
- Tawam Hospital
Hypocalcemia
Preoperative Vitamin D for Post-thyroidectomy Hypocalcemia
The purpose of this study is to determine if pre-operative vitamin D supplementation lowers the incidence of post-operative transient or permanent hypoparathyroidism in patients undergoing total thyroidectomy.
- Trial name
- NCT01609439
- Testing
- Vitamin D
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Thyroid Nodule
Intervention in Single Thyroid Nodule.
Thyroid nodules are common clinical problem. The incidence is 2-4 per 100,000 people per year, being more common in women and the elderly.
- Trial name
- NCT05658809
- Testing
- thyroidectomy
- Volunteers
- 40 people
- Sponsor
- Assiut University
Total Thyroidectomy
Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy
In this clinical trial, the investigators are seeking to learn if a course of voice therapy, including neck massage, stretches and pain science education in addition to voice exercise and scar massage will effectively treatment…
- Trial name
- Man Total Thy (NCT06383091)
- Testing
- Anterior Neck Manual Therapy, Pain Neuroscience Education, Neck Stretches
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Hypoparathyroidism
Perioperative Parathormone Measurement and Sodium Bicarbonate Infusion Test After Total Thyroidectomy
In the study will be included patients that have undergone total thyroidectomy and do not display obvious clinical or laboratory hypoparathyroidism.
- Trial name
- NCT00793689
- Where
- Greece
- Volunteers
- 127 people
- Sponsor
- Aristotle University Of Thessaloniki
Thyroid Swelling
the Use of Harmonic Scalpel Versus Knot Tying for Total Thyroidectomy
Consecutive patients treated for thyroid enlargement at our institution were evaluated for inclusion. Participants were randomly allocated to receive total thyroidectomy using harmonic scalpel HS or using ligature conventional…
- Trial name
- HS (NCT01189955)
- Testing
- HS total thyroidectomy, conventional total thyroidectomy
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Mansoura University
Thyroid Diseases, Postoperative Voice Change
Oxidized Regenerated Cellulose and Voice Quality After Total Thyroidectomy
This randomized controlled trial evaluated whether placement of oxidized regenerated cellulose (ORC) over the recurrent laryngeal nerves during total thyroidectomy affects early postoperative voice quality.
- Trial name
- NCT07681557
- Testing
- Oxidized Regenerated Cellulose
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara University
Hypocalcemia, Vitamin D Deficiency
The Impact of Vitamin D Deficiency on Hypocalcaemia Following Total Thyroidectomy
Post-operative hypocalcaemia following total thyroidectomy is a well-known complication and becoming a major area of research. Many factors are assumed to increase the incidence of post-thyroidectomy hypocalcaemia, but the impact…
- Trial name
- NCT03063060
- Testing
- vitamin D levels and Calcium levels examination
- Volunteers
- 60 people
- Sponsor
- Hillel Yaffe Medical Center
Thyroid Cancer, Distress
The Effects of T4 Versus T4/T3 on Psychological Distress After Total Thyroidectomy in Thyroid Cancer Patients
The goal of this research is to compare the effects on psychological distress between T4 mono replacement group and T4/T3 combination replacement group after total thyroidectomy in thyroid cancer patients. 1.
- Conditions
- Thyroid Cancer, Distress, Depression, Anxiety
- Trial name
- NCT03024151
- Testing
- Comthyroid, Synthroid
- Where
- 2 sites in South Korea
- Volunteers
- 150 people
- Sponsor
- Inje University
Voice Change, Hypocalcemia
The Use of Dexamethasone in Total Thyroidectomy to Improve Voice Outcome and Hypocalcaemia
Thyroidectomy is a standard procedure for benign and malignant pathologies of the thyroid gland. Each year, some 100 total thyroidectomies are performed in Kowloon East Cluster, Hospital Authority, Hong Kong.
- Trial name
- NCT05732883
- Testing
- Dexamethasone, Normal saline
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tseung Kwan O Hospital, Hong Kong
Patients With Thyroidectomy (Scheduled)
Clinical Trial to Evaluate the Efficacy and Safety of Adhesion Barrier Mediclore Versus no Treatment in Patients With Total Thyroidectomy
A randomized, single-blind, multi-center, Phase III clinical trial to evaluate the efficacy and safety of adhesion barrier Mediclore versus no treatment in patients with total thyroidectomy
- Trial name
- NCT02940210
- Testing
- Mediclore® (adhesion barrier)
- Where
- South Korea
- Volunteers
- 172 people
- Sponsor
- CGBio Inc.
Postoperative Hypoparathyroidism, Thyroid Disease
Assessing Benefits of NIRAF Detection for Identifying Parathyroid Glands During Total Thyroidectomy
This study describes a single center, randomized, single-blinded clinical trial to assess the clinical benefits of the use of near infrared autofluorescence (NIRAF) detection with an FDA-cleared device 'Parathyroid Eye (PTeye)'…
- Conditions
- Postoperative Hypoparathyroidism, Thyroid Disease, Thyroid Neoplasms, Thyroid Cancer
- Trial name
- NCT05579782
- Testing
- NIRAF Detection Technology
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Total Thyroidectomy, Parathyroid Function Low Adverse Event
Protective Effect of Indocyanine Green Fluorescence Imaging Technology on Parathyroid Glands During Total Thyroidectomy
Accurate identification and evaluation of the parathyroid glands (PGs) intraoperatively is critical to reduce the incidence of postoperative hypoparathyroidism after total thyroidectomy.
- Conditions
- Total Thyroidectomy, Parathyroid Function Low Adverse Event, Parathyroid Glands--Diseases, Indocyanine Green
- Trial name
- NCT06288750
- Testing
- Indocyanine Green, No indocyanine green
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shandong Linglong Yingcheng Hospital
Hypocalcemia, Total Thyroidectomy
Determination of Parathyroid Function by Fluorescence With Indocyanine Green (ICG) After Total Thyroidectomy
The intensity of parathyroid fluorescence that occurs after intravenous injection of indocyanine green during the performance of a total thyroidectomy correlates with postoperative parathyroid function and could be used as a…
- Conditions
- Hypocalcemia, Total Thyroidectomy, Hypoparathyroidism Postprocedural
- Trial name
- NCT04012476
- Testing
- Indocyanine Green
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Son Espases
Hashimoto's Disease
Hashimoto - a Surgical Disease. Total Thyroidectomy Makes Antibodies Disappear and Ameliorates Symptoms
The investigators have already proven that absolute total thyroidectomy gives elimination of anti-TPO antibodies. Our hypothesis is that this elimination also eliminates the typical Hashimoto symptoms, namely: Serious tiredness…
- Trial name
- NCT02319538
- Testing
- Total thyroidectomy performed
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Sykehuset Telemark
Basedow Disease
Clinical and Surgical Outcomes of Total Thyroidectomy in Basedow's Disease: the Effect of Lugol Solution
Preoperative preparation of patient with Basedow's disease is crucial to avoid severe thyrotoxicosis resulting from leakage of thyroid hormone into the circulation at the time of surgery.
- Trial name
- BALU (NCT05784792)
- Testing
- Lugol -
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Padova
Hypocalcemia, Parathyroid
Comparing PTeye-assisted Versus Conventional Total Thyroidectomy
This is a prospective, single-blinded, randomized controlled trial to evaluate whether PTeye™ can reduce post-operative hypoparathyroidism (PH).
- Conditions
- Hypocalcemia, Parathyroid, Hypoparathyroidism Post-surgical, Total Thyroidectomy
- Trial name
- NCT07416149
- Testing
- PTeye™ parathyroid detection system
- Where
- Hong Kong
- Volunteers
- 210 people
- Sponsor
- The University of Hong Kong
Surgical Stress Response, Total Thyroidectomy
The Association Between Bilateral Intermediate Cervical Plexus Block and Salivary Biomarkers of Surgical Stress Response Following Total Thyroidectomy
The aim of this study is to evaluate how an ultrasound-guided bilateral intermediate cervical plexus block affects the surgical stress response in individuals undergoing total thyroidectomy.
- Conditions
- Surgical Stress Response, Total Thyroidectomy, Saliva Collection, Cervical Plexus Block
- Trial name
- NCT07721818
- Testing
- Ultrasound guided bilateral intermediate cervical plexus block
- Volunteers
- 48 people
- Sponsor
- University Hospital Dubrava