Clinical trials: Total Knee Arthoplasty
Total Knee Arthoplasty
Antibiotic Loaded Cement After TKA
This study will provide us with clear information about the postoperative concentration of antibiotic reached in synovial fluid, thereby helping surgeons to determine if concentration could potentially prevent the growth and…
- Trial name
- NCT05429671
- Testing
- total knee arthroplasty, Tobramycin, Gentamicin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Knee Arthropathy, Postoperative Pain
IPACK Block After Total Knee Arthroplasty
Adductor canal block (ACB) is a peripheral nerve blockade technique that provides good pain control in patients undergoing total knee arthroplasty (TKA) which however does not relieve posterior knee pain.
- Trial name
- NCT04295421
- Testing
- adductor canal block, IPACK block
- Where
- Tunisia
- Volunteers
- 88 people
- Sponsor
- University Tunis El Manar
Total Knee Arthoplasty, Knee Pain
TENS in Post-operative Total Knee Arthroplasty Recovery and Intra-venous Analgesics Requirement
Total knee arthroplasty (TKA) is among the major advancements for the treatment of knee pain and improvement of physical function when conservative management fails to comply with.
- Trial name
- NCT05470244
- Testing
- Routine Physical Therapy and Intra-venous analgesic regimen, Transcutaneous Electrical Nerve Stimulation along with Routine Physical Therapy and Intra-venous analgesic regimen
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Postoperative Delirium (POD), Perioperative Neurocognitive Disorders
Ortopod CZ Pilot Study
ORTOPOD PILOT STUDY is a non-randomized, non-interventional clinical study that addresses the issue of perioperative neurocognitive disorder (deterioration of cognitive functions in the preoperative and perioperative period) and…
- Trial name
- ORTOPODCZ (NCT06869876)
- Where
- Czechia
- Volunteers
- 75 people
- Sponsor
- Tomas Bata Hospital, Czech Republic
Caregiver Burnout
Understanding Caregiver Burden for Hip and Knee Replacement Surgery Patients
Caregiver burden is the response to the emotional, financial, physical, psychological, and social stressors associated with having to care for another family member.
- Trial name
- NCT04838197
- Testing
- Questionnaires and Surveys
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Women's College Hospital
Total Knee Arthoplasty
Effects of a Perioperative Action Observation and Motor Imagery Training in Patients Undergoing Total Knee Arthroplasty
The study is aimed at investigating the effects of action observation and motor imagery training in patients undergoing total knee arthroplasty.
- Trial name
- NCT05459766
- Testing
- Action observation and motor imagery, Usual care
- Volunteers
- 50 people
- Sponsor
- Istituto Clinico Humanitas
Opioid Use, Opioid Use, Unspecified
Patient Utilization of Opioid Destruction Bags in the Post-op Period
This is a study on how patients use and store opioid pain medications at home after surgery and what happens to left over pills when patients are done taking them.
- Conditions
- Opioid Use, Opioid Use, Unspecified, Patient Empowerment, Total Knee Arthoplasty
- Trial name
- NCT05875857
- Testing
- Opioid destruction education
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- University of Nebraska
Knee Arthroplasty, Total
BLOCK-study: Better Local Orthopedic Pain Control After Knee Arthroplasty
The goal of this study is to compare the anesthetic combination iPACK with femoral triangle block versus surgical LIA for unilateral TKA.
- Trial name
- BLOCK (NCT06746168)
- Testing
- Locoregional anesthesia, Local Anesthetic Ropivacaine
- Where
- Belgium
- Volunteers
- 210 people
- Sponsor
- Jessa Hospital
Arthoplasty, Pain, Anxiety
Effect of Progressive Muscle Relaxation on Fear of Falling, Pain, and Anxiety in Arthroplasty Patients
The study will be conducted using a parallel-group randomized controlled experimental design to determine the effect of progressive muscle relaxation exercises on postoperative fear of falling, pain, and anxiety levels in…
- Trial name
- PMRE (NCT07098390)
- Testing
- Progressive Muscle Relaxation Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Gazi University
Total Knee Arthoplasty
Robotic-assisted Versus Conventional Total Knee Arthroplasty
This is a multicenter, prospective and randomized controlled pre-market clinical Trial. Study subjects will be randomized into one of two operative groups: 1) TKA assisted with ROSA® Knee System; 2) TKA with conventional surgical…
- Trial name
- NCT04982198
- Testing
- ROSA assisted TKA
- Where
- China
- Volunteers
- 99 people
- Sponsor
- Zimmer Biomet
Arthroplasty Complications, Total Knee Arthroplasty
Is Self-transfusion Safe After Total Knee Arthroplasty in Terms of Nephrotoxicity of Gentamicin From Bone Cement?
Considering that the high local concentration of antibiotic from bone cement is delivered intravenously through the self-transfusion process, systematic toxicity has never been evaluated.
- Trial name
- NCT04505748
- Testing
- Self-transfusion device
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University Hospital, Alexandroupolis
Telerehabilitation, Total Knee Arthoplasty
Telerehabilitation After Total Knee Arthroplasty
The aim of this study was to assess the function, pain intensity and walking distance in patients prior to and after total knee arthroplasty, who received therapy either in a clinic under direct supervision of a physical…
- Conditions
- Telerehabilitation, Total Knee Arthoplasty, Physiotherapy
- Trial name
- NCT04923373
- Testing
- telerehabilitation, standard physiotherapy
- Where
- Poland
- Volunteers
- 105 people
- Sponsor
- University of Rzeszow
Total Knee Arthroplasty
A Prospective, Randomized, Controlled Study Comparing Three Tibial Component Designs in Total Knee Arthoplasty
SUMMARY A prospective, randomized, single-blinded clinical trial is proposed to compare three tibial tray designs for patients undergoing total knee arthroplasty.
- Trial name
- NCT00589147
- Testing
- The Zimmer NexGen Legacy Knee System, modular cemented tibia, The Zimmer NexGen Legacy Knee System, non-modular cemented tibia., The Zimmer NexGen Legacy Knee System, non-modular uncemented tibia
- Where
- United States
- Volunteers
- 397 people
- Sponsor
- Mayo Clinic
Total Knee Arthroplasty Recovery
Effects of Progressive Restricted Blood Flow Exercises in Post Total Knee Arthroplasty
Total knee arthroplasty (TKA) is a commonly performed procedure for advanced knee osteoarthritis. Despite successful surgery, many patients experience postoperative impairments including pain, reduced range of motion (ROM)…
- Trial name
- TKA PBFR (NCT07601906)
- Testing
- Blood Flow Restriction Exercises and Conventional Physical Therapy, Conventional Physical Therapy alone
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Mild Cognitive Impairment (MCI), Opioid Use
Postsurgical Pain and Opioid Use in Older Adults: Effects of Mild Cognitive Impairment
Mild cognitive impairment (MCI) affects a substantial proportion of older adults undergoing major surgery and may alter pain processing, pain experience, and opioid use after surgery.
- Conditions
- Mild Cognitive Impairment (MCI), Opioid Use, Cognitive Dysfunction, Postoperative Pain
- Trial name
- NCT07885085
- Where
- United States
- Volunteers
- 552 people
- Sponsor
- Miklos Kertai