Clinical trials: Total Knee Anthroplasty, active
Total Knee Anthroplasty, Epidural Analgesia
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Postoperative Analgesia After Total Knee Arthroplasty
The goal of this clinical trial is to compare two different epidural analgesia delivery methods for pain control after total knee arthroplasty in adults undergoing elective surgery.
- Trial name
- NCT07605208
- Testing
- Programmed intermittent epidural bolus 6 ml, continuous epidural infusion
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sakarya University
Osteo Arthritis of the Knee, Total Knee Anthroplasty
Dinalbuphine Sebacate in Postoperative Pain Control After TKA
To evaluate the effectiveness of Dinalbuphine Sebacate for controlling subacute pain after total knee arthroplasty
- Trial name
- Naldebain (NCT07140510)
- Testing
- Dinalbuphine Sebacate, Normal Saline
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Thammasat University
Knee Osteoarthristis, Total Knee Anthroplasty
Prospective, In-Vivo, Post-Market Safety and Efficacy Surveillance Registry of the MAXX Orthopedics, Freedom Total Knee® System
In an effort to satisfy regulatory requirements for post-market surveillance of product safety and efficacy, a representative sample of patients will be recruited for prospective monitoring.
- Trial name
- NCT06627699
- Testing
- Total Knee Arthroplasty
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Maxx Orthopedics Inc
Osteoarthritis (OA) of the Knee, Total Knee Anthroplasty
Comparison of Restricted Versus Unrestricted Kinematic Alignment in 1ry TKA
Knee osteoarthritis is a growing socioeconomic burden because of the ageing and obesity. By 2030, the majority of individuals undergoing knee arthroplasty in USA will be those younger than 65 years, with up to 1 million achieved…
- Trial name
- rKA-KA-TKA (NCT06726993)
- Testing
- Total knee arthroplasty
- Volunteers
- 80 people
- Sponsor
- Assiut University
Total Knee Anthroplasty
Smart Knee Evaluation of Exparel and Zynrelef in TKA Recovery
This study looks at how three different numbing injections affect how quickly patients recover after knee replacement surgery (total knee arthroplasty, or TKA).
- Trial name
- NCT07878507
- Testing
- Intra-articular injection of bupivacaine in the knee joint, intra-articular injection of Exparel in the knee joint, Zynrelef
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Foundation for Orthopaedic Research and Education
Total Knee Anthroplasty, Venous Insufficiency (Chronic)(Peripheral)
Impact of Chronic Venous Insufficiency on Outcomes After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is an effective treatment for end-stage knee osteoarthritis; however, postoperative complications-particularly wound healing problems-remain a significant concern.
- Conditions
- Total Knee Anthroplasty, Venous Insufficiency (Chronic)(Peripheral), Doppler Ultrasound Diagnosis
- Trial name
- VENOUS-TKA (NCT07577141)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- SB Istanbul Education and Research Hospital
Total Knee Anthroplasty
"The Effect of AI-Assisted Mobilization Education on Kinesiophobia and Readiness for Hospital Discharge in Patients Undergoing Total Knee Arthroplasty''
The aim of this study is to investigate the effect of artificial intelligence-assisted mobilization education provided to patients undergoing total knee arthroplasty on their level of kinesiophobia and readiness for hospital…
- Trial name
- NCT07694895
- Testing
- Artificial intelligence-assisted mobilization education video
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Kocaeli University
Total Knee Anthroplasty, Cryotherapy
Monocentric Randomised Controlled Trial Assessing Cryocompression Following Total Knee Replacement
Immediately following surgery, icepacks are commonly used to decrease inflammation and reduce pain and have demonstrated to decrease post-operative opioid consumption.
- Conditions
- Total Knee Anthroplasty, Cryotherapy, Compression
- Trial name
- CryoTKR (NCT07366736)
- Testing
- Cryotherapy, Game Ready
- Where
- France
- Volunteers
- 138 people
- Sponsor
- Clinique des Cèdres
Total Knee Anthroplasty
The Effect of Kinesio Taping on Mobility, Pain, Balance and Daily Activities in Total Knee Replacement Patients
Total knee arthroplasty (TKA) is a surgical procedure performed to relieve pain and functional limitations caused by advanced gonarthrosis that cannot be managed with conservative methods.
- Trial name
- NCT06911814
- Testing
- kinesio taping, THE EXERCİSE
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Total Knee Anthroplasty, Osteoarthritis(Primary)
COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty
Through a triple-blinded randomized control trial, the primary purpose of this pilot study is to assess the efficacy of administering peri-operative contralateral corticosteroid injection in patients undergoing TKA.
- Conditions
- Total Knee Anthroplasty, Osteoarthritis(Primary), Osteoarthritis (OA) of the Knee, Bilateral Knee Osteoarthritis
- Trial name
- COSTI (NCT06809998)
- Testing
- Corticosteroid Injection - 80mg methylprednisolone (total volume 2ml) with 6 mL of 1% Bupivacaine without epinephrine (Total Volume 8 mL)., Band-Aid
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Unity Health Toronto
Knee Osteoarthritis (OA), Total Knee Anthroplasty
Tourniquet Vs. No-Tourniquet Technique in Total Knee Arthroplasty at the University Hospital of the West Indies
The goal of this clinical trial is to determine whether performing total knee replacement surgery (total knee arthroplasty, TKA) without a tourniquet is clinically equivalent to performing the procedure with a tourniquet in…
- Trial name
- NCT07506434
- Testing
- pneumatic tourniquet
- Where
- Jamaica
- Volunteers
- 30 people
- Sponsor
- The University of The West Indies
Knee Osteoarthritis (Knee OA), Total Knee Anthroplasty
Drain Removal Before Versus After CPM in Primary Total Knee Arthroplasty
The aim of this prospective randomized controlled study was to determine whether the timing of drain removal in relation to continuous passive motion (CPM) application influences postoperative residual hematoma formation…
- Conditions
- Knee Osteoarthritis (Knee OA), Total Knee Anthroplasty, Postoperative Hematoma
- Trial name
- NCT07302724
- Testing
- Drain Removal Before CPM, Drain Removal After CPM
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Ankara Etlik City Hospital
Total Knee Anthroplasty, Total Knee Arthroplasty Recovery
The Effects of Mir Shakeel Teleintegrated Therapy Plan in Patients Undergoing Total Knee Arthroplasty
This randomized controlled trial aims to evaluate the effectiveness of a newly developed Modified Structured Telerehabilitation Intervention Protocol (MSTITP) compared with conventional in-person physical therapy in patients…
- Trial name
- RCT (NCT07239258)
- Testing
- Mir Shakeel Teleintegrated Therapy plan, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Lincoln University College Malaysia
Osteoarthritis (OA), Osteoarthritis (OA) of the Hip
Evaluation of Choose to Move Replacement Ready (CTM-RR)
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Osteoarthritis (OA), Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee, Total Knee Anthroplasty
- Trial name
- CTM-RR (NCT07696650)
- Testing
- Choose to Move Replacement Ready
- Where
- Canada
- Volunteers
- 210 people
- Sponsor
- University of British Columbia
Acupuncture Analgesia, Acupuncture
ACU_Knee: Role of Acupuncture in Knee Prosthetic Surgery
Post-operative analgesia after total knee arthroplasty (TKA) has always been a challenge in the anesthesiological setting, having to combine good pain control and the need for early mobilization, both factors that can affect the…
- Conditions
- Acupuncture Analgesia, Acupuncture, Acupuncture Therapy, Total Knee Anthroplasty
- Trial name
- ACU_Knee (NCT07123805)
- Testing
- Acupuncture group
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Joint Contractures, Total Knee Anthroplasty
Knee Flexionater to Avoid Motion Restoring Surgery
The goal of this clinical trial is to learn whether adding a stretching device to standard physical therapy can help people regain knee bending after total knee replacement surgery.
- Conditions
- Joint Contractures, Total Knee Anthroplasty, Knee Arthrofibrosis
- Trial name
- NCT07454356
- Testing
- Hydraulic high Intensity Stretch Device, Standard Physical Therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Ermi LLC
Pain Postoperative, Total Knee Anthroplasty
Comparative Analgesic Effect After Total Knee Arthroplasty Between Intraosseous and Peri-articular Injection
The goal of this RCT is to compare analgesic effect after total knee arthroplasty between intraosseous multimodal analgesic agent injection versus periarticular injection.
- Conditions
- Pain Postoperative, Total Knee Anthroplasty, Functional Outcomes
- Trial name
- NCT06800846
- Testing
- Intraosseous Morphine, Periarticular Injection
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Thammasat University Hospital
Total Knee Anthroplasty, Postoperative Pain
Proximal Spread in Adductor Canal Block(ACB)
This prospective, randomized clinical study is designed to evaluate the effects of two different injection levels of adductor canal block (ACB) on the proximal spread of local anesthetic and clinical outcomes in patients…
- Trial name
- ACB (NCT07595471)
- Testing
- Comparison of Proximal Adductor Canal Block, Comparison True Distal Adductor Canal Block.
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara Etlik City Hospital
Total Knee Anthroplasty
Effect of Combined Adductor Canal and AFCN Block on Postoperative Inflammation
The aim of this thesis is to evaluate the effects of adding an anterior femoral cutaneous nerve (AFCN) block to the adductor canal block used for postoperative analgesia after total knee arthroplasty on the postoperative…
- Trial name
- NCT07367009
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Total Knee Anthroplasty, Regional Anesthesia
The Sacral Erector Spinae Plane Block in Total Knee Arthroplasty
The goal of this observational study is to learn about the analgesic efficacy and postoperative recovery of two locoregional anesthesia combinations in patients > 18 years (ASA I-III), scheduled for unilateral TKA under spinal…
- Trial name
- sacral ESP (NCT07017400)
- Testing
- Local Anesthetic Injection
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- San Giovanni di Dio Hospital